pyrilamine has been researched along with Rheumatoid Arthritis in 3 studies
Pyrilamine: A histamine H1 antagonist. It has mild hypnotic properties and some local anesthetic action and is used for allergies (including skin eruptions) both parenterally and locally. It is a common ingredient of cold remedies.
mepyramine : An ethylenediamine derivative that is ethylenediamine in which one of the amino nitrogens is substituted by two methyl groups and the remaining amino nitrogen is substituted by a 4-methoxybenzyl and a pyridin-2-yl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Histamine H1 receptors have been demonstrated on adherent rheumatoid synovial cells using biochemical and radioligand binding assays in vitro." | 1.27 | Histamine H1 receptors on adherent rheumatoid synovial cells in culture: demonstration by radioligand binding and inhibition of histamine-stimulated prostaglandin E production by histamine H1 antagonists. ( Taylor, DJ; Woolley, DE, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Permin, H | 1 |
| Skov, PS | 1 |
| Norn, S | 1 |
| Geisler, A | 1 |
| Klysner, R | 1 |
| Andersen, V | 1 |
| Wiik, A | 1 |
| Manthorpe, R | 1 |
| Nielsen, H | 1 |
| Petersen, J | 1 |
| Taylor, DJ | 2 |
| Woolley, DE | 2 |
3 other studies available for pyrilamine and Rheumatoid Arthritis
| Article | Year |
|---|---|
Possible role of histamine in rheumatoid arthritis. Treatment with cimetidine and mepyramine.
Topics: Adolescent; Adult; Aminopyridines; Arthritis, Rheumatoid; Cimetidine; Drug Therapy, Combination; Fem | 1981 |
Evidence for both histamine H1 and H2 receptors on human articular chondrocytes.
Topics: Arthritis, Rheumatoid; Cartilage, Articular; Cells, Cultured; Chlorpheniramine; Cyclic AMP; Histamin | 1987 |
Histamine H1 receptors on adherent rheumatoid synovial cells in culture: demonstration by radioligand binding and inhibition of histamine-stimulated prostaglandin E production by histamine H1 antagonists.
Topics: Arthritis, Rheumatoid; Binding, Competitive; Cells, Cultured; Chlorpheniramine; Histamine; Histamine | 1987 |