n(g),n(g')-dimethyl-l-arginine has been researched along with Rheumatoid Arthritis in 27 studies
N,N-dimethylarginine: asymmetric dimethylarginine; do not confuse with N,N'-dimethylarginine
| Excerpt | Relevance | Reference |
|---|---|---|
| "The relationship between plasma arginine metabolites influencing vascular homeostasis and peripheral vasodilatory capacity in rheumatoid arthritis (RA) patients is not known." | 7.96 | Comprehensive arginine metabolomics and peripheral vasodilatory capacity in rheumatoid arthritis: A monocentric cross-sectional study. ( Bassu, S; Carru, C; Castagna, F; Erre, GL; Mangoni, AA; Passiu, G; Piga, M; Sotgia, S; Zinellu, A, 2020) |
| "Eighteen rheumatoid arthritis patients who had not taken prednisolone for >6 months (non-glucocorticoid (GC) users), 18 rheumatoid arthritis patients taking continuous oral prednisolone (6." | 7.85 | Opposing effects of rheumatoid arthritis and low dose prednisolone on arginine metabolomics. ( Burt, MG; Drake, SM; Mangelsdorf, BL; Mangoni, AA; Radhakutty, A; Rowland, A; Smith, MD; Thompson, CH, 2017) |
| "The aim of our study was to determine whether asymmetric dimethylarginine (ADMA) levels are associated with homocysteine (Hcy) and methylenetetrahydrofolate reductase (MTHFR) C677T (rs1801133) gene variants in patients with rheumatoid arthritis (RA)." | 7.83 | Associations between asymmetric dimethylarginine, homocysteine, and the methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism (rs1801133) in rheumatoid arthritis. ( Dimitroulas, T; Douglas, KM; Hodson, J; Kitas, GD; Sandoo, A; Smith, J, 2016) |
| "The aim of our study was to determine whether Dimethylarginine Dimethylaminohydrolase (DDAH) 1 and 2 gene polymorphisms - the main enzyme involved in ADMA degradation - are associated with high Asymmetric Dimethylarginine (ADMA) levels in Rheumatoid Arthritis (RA)." | 7.80 | Relationship between dimethylarginine dimethylaminohydrolase gene variants and asymmetric dimethylarginine in patients with rheumatoid arthritis. ( Dimitroulas, T; Hodson, J; Kitas, GD; Panoulas, VF; Sandoo, A; Smith, J, 2014) |
| "To determine whether demographic, inflammatory, and metabolic factors predict elevated asymmetric dimethylarginine (ADMA) levels in rheumatoid arthritis (RA)." | 7.79 | Predictors of asymmetric dimethylarginine levels in patients with rheumatoid arthritis: the role of insulin resistance. ( Dimitroulas, T; Hodson, J; Kitas, GD; Metsios, GS; Sandoo, A; Smith, JP; Stavropoulos-Kalinoglou, A; Veldhuijzen van Zanten, JJ, 2013) |
| "Global L-arginine bioavailability was diminished, whereas plasma arginase activity, ADMA, and SDMA levels were elevated, in patients with RA compared with healthy control subjects." | 5.48 | Elevated levels of plasma symmetric dimethylarginine and increased arginase activity as potential indicators of cardiovascular comorbidity in rheumatoid arthritis. ( Chandrasekharan, UM; Elaine Husni, M; Hazen, SL; Wang, S; Wang, Z; Wilson Tang, WH; Wu, Y, 2018) |
| "The relationship between plasma arginine metabolites influencing vascular homeostasis and peripheral vasodilatory capacity in rheumatoid arthritis (RA) patients is not known." | 3.96 | Comprehensive arginine metabolomics and peripheral vasodilatory capacity in rheumatoid arthritis: A monocentric cross-sectional study. ( Bassu, S; Carru, C; Castagna, F; Erre, GL; Mangoni, AA; Passiu, G; Piga, M; Sotgia, S; Zinellu, A, 2020) |
| "Eighteen rheumatoid arthritis patients who had not taken prednisolone for >6 months (non-glucocorticoid (GC) users), 18 rheumatoid arthritis patients taking continuous oral prednisolone (6." | 3.85 | Opposing effects of rheumatoid arthritis and low dose prednisolone on arginine metabolomics. ( Burt, MG; Drake, SM; Mangelsdorf, BL; Mangoni, AA; Radhakutty, A; Rowland, A; Smith, MD; Thompson, CH, 2017) |
| "The aim of our study was to determine whether asymmetric dimethylarginine (ADMA) levels are associated with homocysteine (Hcy) and methylenetetrahydrofolate reductase (MTHFR) C677T (rs1801133) gene variants in patients with rheumatoid arthritis (RA)." | 3.83 | Associations between asymmetric dimethylarginine, homocysteine, and the methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism (rs1801133) in rheumatoid arthritis. ( Dimitroulas, T; Douglas, KM; Hodson, J; Kitas, GD; Sandoo, A; Smith, J, 2016) |
| "The aim of our study was to determine whether Dimethylarginine Dimethylaminohydrolase (DDAH) 1 and 2 gene polymorphisms - the main enzyme involved in ADMA degradation - are associated with high Asymmetric Dimethylarginine (ADMA) levels in Rheumatoid Arthritis (RA)." | 3.80 | Relationship between dimethylarginine dimethylaminohydrolase gene variants and asymmetric dimethylarginine in patients with rheumatoid arthritis. ( Dimitroulas, T; Hodson, J; Kitas, GD; Panoulas, VF; Sandoo, A; Smith, J, 2014) |
| "To determine whether demographic, inflammatory, and metabolic factors predict elevated asymmetric dimethylarginine (ADMA) levels in rheumatoid arthritis (RA)." | 3.79 | Predictors of asymmetric dimethylarginine levels in patients with rheumatoid arthritis: the role of insulin resistance. ( Dimitroulas, T; Hodson, J; Kitas, GD; Metsios, GS; Sandoo, A; Smith, JP; Stavropoulos-Kalinoglou, A; Veldhuijzen van Zanten, JJ, 2013) |
| "For AS patients, the Bath Ankylosing Spondylitis Disease Activity Index (BASDAI), back pain VAS and patient's global activity of disease were calculated." | 2.78 | Disparate effects of anti-TNF-α therapies on measures of disease activity and mediators of endothelial damage in ankylosing spondylitis. ( Gąsowski, J; Grodzicki, T; Jeka, S; Korkosz, M; Leszczyński, P; Pawlak-Buś, K; Siedlar, M; Surdacki, A, 2013) |
| "Global L-arginine bioavailability was diminished, whereas plasma arginase activity, ADMA, and SDMA levels were elevated, in patients with RA compared with healthy control subjects." | 1.48 | Elevated levels of plasma symmetric dimethylarginine and increased arginase activity as potential indicators of cardiovascular comorbidity in rheumatoid arthritis. ( Chandrasekharan, UM; Elaine Husni, M; Hazen, SL; Wang, S; Wang, Z; Wilson Tang, WH; Wu, Y, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (7.41) | 29.6817 |
| 2010's | 23 (85.19) | 24.3611 |
| 2020's | 2 (7.41) | 2.80 |
| Authors | Studies |
|---|---|
| Erre, GL | 2 |
| Mangoni, AA | 3 |
| Passiu, G | 1 |
| Bassu, S | 1 |
| Castagna, F | 1 |
| Carru, C | 2 |
| Piga, M | 2 |
| Zinellu, A | 2 |
| Sotgia, S | 2 |
| Tommasi, S | 1 |
| Paliogiannis, P | 1 |
| Cauli, A | 1 |
| Pintus, G | 1 |
| Dimitroulas, T | 8 |
| Hodson, J | 6 |
| Panoulas, VF | 2 |
| Sandoo, A | 7 |
| Smith, J | 3 |
| Kitas, G | 1 |
| Radhakutty, A | 1 |
| Mangelsdorf, BL | 1 |
| Drake, SM | 1 |
| Rowland, A | 1 |
| Smith, MD | 1 |
| Thompson, CH | 1 |
| Burt, MG | 1 |
| Di Franco, M | 4 |
| Lucchino, B | 2 |
| Conti, F | 2 |
| Valesini, G | 4 |
| Spinelli, FR | 4 |
| Chandrasekharan, UM | 1 |
| Wang, Z | 1 |
| Wu, Y | 1 |
| Wilson Tang, WH | 1 |
| Hazen, SL | 1 |
| Wang, S | 1 |
| Elaine Husni, M | 1 |
| Zhao, CN | 1 |
| Wu, Q | 1 |
| Mao, YM | 1 |
| Liu, LN | 1 |
| Dan, YL | 1 |
| Li, XM | 1 |
| Wang, DG | 1 |
| Pan, HF | 1 |
| Kitas, GD | 7 |
| Chen, XM | 1 |
| Xia, J | 1 |
| Zhou, T | 1 |
| Yuan, Q | 1 |
| Zhang, WF | 1 |
| Hu, CP | 1 |
| Li, YJ | 1 |
| Jiang, JL | 1 |
| Korkosz, M | 3 |
| Gąsowski, J | 1 |
| Surdacki, A | 4 |
| Leszczyński, P | 1 |
| Pawlak-Buś, K | 1 |
| Jeka, S | 1 |
| Siedlar, M | 1 |
| Grodzicki, T | 1 |
| Metere, A | 3 |
| Barbati, C | 1 |
| Pierdominici, M | 1 |
| Iannuccelli, C | 3 |
| Ciciarello, F | 2 |
| Agati, L | 3 |
| Smith, JP | 4 |
| Klimek, E | 1 |
| Skalska, A | 1 |
| Kwaśny-Krochin, B | 1 |
| Sulicka, J | 2 |
| Fedak, D | 1 |
| Kierzkowska, I | 1 |
| Wizner, B | 1 |
| Grodzicki, TK | 1 |
| Kayacelebi, AA | 2 |
| Pham, VV | 2 |
| Willers, J | 2 |
| Hahn, A | 2 |
| Stichtenoth, DO | 1 |
| Jordan, J | 1 |
| Tsikas, D | 2 |
| Douglas, KM | 2 |
| Schneider, JY | 1 |
| Rothmann, S | 1 |
| Frölich, JC | 1 |
| Turiel, M | 2 |
| Atzeni, F | 2 |
| Tomasoni, L | 2 |
| de Portu, S | 1 |
| Delfino, L | 1 |
| Bodini, BD | 1 |
| Longhi, M | 2 |
| Sitia, S | 2 |
| Bianchi, M | 1 |
| Ferrario, P | 1 |
| Doria, A | 1 |
| De Gennaro Colonna, V | 2 |
| Sarzi-Puttini, P | 2 |
| Cicala, S | 1 |
| Gianturco, L | 1 |
| Ricci, C | 1 |
| Toms, TE | 1 |
| Veldhuijzen van Zanten, JJ | 2 |
| Gerardi, MC | 1 |
| Conti, V | 1 |
| Boccalini, F | 1 |
| Angel, K | 1 |
| Provan, SA | 1 |
| Mowinckel, P | 1 |
| Seljeflot, I | 1 |
| Kvien, TK | 1 |
| Atar, D | 1 |
| Metsios, GS | 1 |
| Stavropoulos-Kalinoglou, A | 1 |
| Martens-Lobenhoffer, J | 1 |
| Wloch, A | 1 |
| Marewicz, E | 1 |
| Rakowski, T | 1 |
| Wieczorek-Surdacka, E | 1 |
| Dubiel, JS | 1 |
| Pryjma, J | 1 |
| Bode-Böger, SM | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Evaluation of a New Score Incorporating Endothelial Dysfunction for the Assessment of Coronary Heart Disease Risk in Patients With Rheumatoid Arthritis: a 3-year Prospective Study.[NCT02341066] | 3,000 participants (Anticipated) | Observational | 2015-07-31 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 reviews available for n(g),n(g')-dimethyl-l-arginine and Rheumatoid Arthritis
| Article | Year |
|---|---|
Asymmetric Dimethylarginine: a Key Player in the Pathophysiology of Endothelial Dysfunction, Vascular Inflammation and Atherosclerosis in Rheumatoid Arthritis?
Topics: Arginine; Arthritis, Rheumatoid; Atherosclerosis; Endothelial Cells; Endothelium, Vascular; Humans; | 2021 |
Asymmetric Dimethyl Arginine as a Biomarker of Atherosclerosis in Rheumatoid Arthritis.
Topics: Animals; Arginine; Arthritis, Rheumatoid; Atherosclerosis; Biomarkers; Humans | 2018 |
Elevated circulating asymmetric dimethylarginine levels in rheumatoid arthritis: a systematic review and meta-analysis.
Topics: Arginine; Arthritis, Rheumatoid; Biomarkers; Case-Control Studies; Humans; Risk Factors | 2019 |
Genetic regulation of dimethylarginines and endothelial dysfunction in rheumatoid arthritis.
Topics: Arginine; Arthritis, Rheumatoid; Atherosclerosis; Biomarkers; Cardiovascular Diseases; Endothelium, | 2019 |
5 trials available for n(g),n(g')-dimethyl-l-arginine and Rheumatoid Arthritis
| Article | Year |
|---|---|
Genetic variations in the alanine-glyoxylate aminotransferase 2 (AGXT2) gene and dimethylarginines levels in rheumatoid arthritis.
Topics: Aged; Arginine; Arthritis, Rheumatoid; Female; Humans; Male; Middle Aged; Polymorphism, Single Nucle | 2017 |
Disparate effects of anti-TNF-α therapies on measures of disease activity and mediators of endothelial damage in ankylosing spondylitis.
Topics: Adalimumab; Adult; Antibodies, Monoclonal, Humanized; Antirheumatic Agents; Arginine; Arthritis, Rhe | 2013 |
Decrease of asymmetric dimethyl arginine after anti-TNF therapy in patients with rheumatoid arthritis.
Topics: Adalimumab; Adult; Antibodies, Monoclonal, Humanized; Antirheumatic Agents; Arginine; Arthritis, Rhe | 2014 |
Plasma homoarginine, arginine, asymmetric dimethylarginine and total homocysteine interrelationships in rheumatoid arthritis, coronary artery disease and peripheral artery occlusion disease.
Topics: Aged; Arginine; Arthritis, Rheumatoid; Coronary Artery Disease; Female; Homoarginine; Homocysteine; | 2015 |
Serum levels of asymmetric dimethylarginine and apelin as potential markers of vascular endothelial dysfunction in early rheumatoid arthritis.
Topics: Adult; Aged; Antirheumatic Agents; Apelin; Arginine; Arthritis, Rheumatoid; Endothelium, Vascular; F | 2012 |
18 other studies available for n(g),n(g')-dimethyl-l-arginine and Rheumatoid Arthritis
| Article | Year |
|---|---|
Comprehensive arginine metabolomics and peripheral vasodilatory capacity in rheumatoid arthritis: A monocentric cross-sectional study.
Topics: Aged; Aged, 80 and over; Arginine; Arthritis, Rheumatoid; Biomarkers; Case-Control Studies; Citrulli | 2020 |
Opposing effects of rheumatoid arthritis and low dose prednisolone on arginine metabolomics.
Topics: Administration, Oral; Aged; Arginine; Arthritis, Rheumatoid; Biomarkers; Case-Control Studies; Chrom | 2017 |
Elevated levels of plasma symmetric dimethylarginine and increased arginase activity as potential indicators of cardiovascular comorbidity in rheumatoid arthritis.
Topics: Aged; Arginase; Arginine; Arthritis, Rheumatoid; Biomarkers; Cardiovascular Diseases; Comorbidity; F | 2018 |
Involvement of DDAH/ADMA pathway in the pathogenesis of rheumatoid arthritis in rats.
Topics: Amidohydrolases; Animals; Ankle Joint; Arginine; Arthritis, Experimental; Arthritis, Rheumatoid; Cyt | 2013 |
Effect of therapeutic inhibition of TNF on circulating endothelial progenitor cells in patients with rheumatoid arthritis.
Topics: Adalimumab; Adult; Aged; Antibodies, Monoclonal, Humanized; Antigens, CD34; Arginine; Arthritis, Rhe | 2013 |
Asymmetric dimethylarginine is not associated with subendocardial viability ratio in Rheumatoid Arthritis.
Topics: Aged; Arginine; Arthritis, Rheumatoid; Cardiovascular Diseases; Endocardium; Female; Humans; Male; M | 2014 |
Differential associations of inflammatory and endothelial biomarkers with disease activity in rheumatoid arthritis of short duration.
Topics: Adult; Arginine; Arthritis, Rheumatoid; Biomarkers; C-Reactive Protein; E-Selectin; Female; Humans; | 2014 |
Plasma homoarginine (hArg) and asymmetric dimethylarginine (ADMA) in patients with rheumatoid arthritis: is homoarginine a cardiovascular corrective in rheumatoid arthritis, an anti-ADMA?
Topics: Arginine; Arthritis, Rheumatoid; Biomarkers; Female; Homoarginine; Humans; Male | 2014 |
Cumulative inflammation associates with asymmetric dimethylarginine in rheumatoid arthritis: a 6 year follow-up study.
Topics: Aged; Arginine; Arthritis, Rheumatoid; Biomarkers; Blood Sedimentation; C-Reactive Protein; Cardiova | 2015 |
Relationship between dimethylarginine dimethylaminohydrolase gene variants and asymmetric dimethylarginine in patients with rheumatoid arthritis.
Topics: Aged; Amidohydrolases; Analysis of Variance; Arginine; Arthritis, Rheumatoid; Female; Genetic Variat | 2014 |
Associations between asymmetric dimethylarginine, homocysteine, and the methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism (rs1801133) in rheumatoid arthritis.
Topics: Aged; Analysis of Variance; Arginine; Arthritis, Rheumatoid; Cohort Studies; Female; Genotype; Homoc | 2016 |
Non-invasive assessment of coronary flow reserve and ADMA levels: a case-control study of early rheumatoid arthritis patients.
Topics: Adult; Aged; Arginine; Arthritis, Rheumatoid; Biomarkers; Carotid Artery, Common; Case-Control Studi | 2009 |
Effects of long-term disease-modifying antirheumatic drugs on endothelial function in patients with early rheumatoid arthritis.
Topics: Adalimumab; Adult; Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antirheumatic Ag | 2010 |
Dimethylated L-arginine analogues versus autoantibodies in early rheumatoid arthritis.
Topics: Adult; Arginine; Arthritis, Rheumatoid; Autoantibodies; Enzyme-Linked Immunosorbent Assay; Female; H | 2012 |
Clinical remission following treatment with tumour necrosis factor-alpha antagonists is not accompanied by changes in asymmetric dimethylarginine in patients with rheumatoid arthritis.
Topics: Adult; Aged; Antirheumatic Agents; Arginine; Arthritis, Rheumatoid; Biomarkers; Female; Humans; Long | 2012 |
The L-arginine/asymmetric dimethylarginine ratio is improved by anti-tumor necrosis factor-α therapy in inflammatory arthropathies. Associations with aortic stiffness.
Topics: Adult; Antirheumatic Agents; Aorta; Arginine; Arthritis, Psoriatic; Arthritis, Rheumatoid; Blood Pre | 2012 |
Predictors of asymmetric dimethylarginine levels in patients with rheumatoid arthritis: the role of insulin resistance.
Topics: Adult; Aged; Arginine; Arthritis, Rheumatoid; Female; Homeostasis; Humans; Insulin Resistance; Male; | 2013 |
Elevated plasma asymmetric dimethyl-L-arginine levels are linked to endothelial progenitor cell depletion and carotid atherosclerosis in rheumatoid arthritis.
Topics: Adult; Arginine; Arthritis, Rheumatoid; Carotid Arteries; Carotid Artery Diseases; Case-Control Stud | 2007 |