lactic acid has been researched along with Rheumatoid Arthritis in 38 studies
Lactic Acid: A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed)
2-hydroxypropanoic acid : A 2-hydroxy monocarboxylic acid that is propanoic acid in which one of the alpha-hydrogens is replaced by a hydroxy group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Self-reinforcing polylevolactic acid (SR-PLLA) implants have been used in arthrodeses of patients with rheumatoid arthritis." | 7.71 | Long-term results of ankle and triple arthrodeses fixed with self-reinforced polylevolactic acid implants in patients with rheumatoid arthritis. ( Juutilainen, T; Partio, EK; Pätiälä, H; Rokkanen, P; Voutilainen, N, 2001) |
| "Methotrexate (MTX), as a disease modifying antirheumatic drug (DMARD), was first line drug to treat rheumatoid arthritis." | 3.88 | Dual-functional lipid polymeric hybrid pH-responsive nanoparticles decorated with cell penetrating peptide and folate for therapy against rheumatoid arthritis. ( Lee, RJ; Li, Y; Sun, F; Sun, X; Teng, L; Yu, C; Zhang, X; Zhao, J; Zhao, M; Zhou, Y, 2018) |
| "Self-reinforcing polylevolactic acid (SR-PLLA) implants have been used in arthrodeses of patients with rheumatoid arthritis." | 3.71 | Long-term results of ankle and triple arthrodeses fixed with self-reinforced polylevolactic acid implants in patients with rheumatoid arthritis. ( Juutilainen, T; Partio, EK; Pätiälä, H; Rokkanen, P; Voutilainen, N, 2001) |
| "Inflammation is involved in many disease processes." | 1.56 | Lactate Production Precedes Inflammatory Cell Recruitment in Arthritic Ankles: an Imaging Study. ( Beziere, N; Bouzin, C; Comment, A; Daniels, R; Fuchs, K; Kneilling, M; Neveu, MA; Pichler, BJ; Schmid, AM; Schwenck, J, 2020) |
| " In addition, proper siRNA dosing seems to be important for a positive therapeutic outcome in vivo." | 1.38 | MRI-assessed therapeutic effects of locally administered PLGA nanoparticles loaded with anti-inflammatory siRNA in a murine arthritis model. ( Colombo, S; Foged, C; Jensen, LB; Lammers, T; Nicolay, K; Nielsen, HM; Schiffelers, RM; Storm, G; Strijkers, GJ; te Boekhorst, BC; Varkouhi, AK, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (13.16) | 18.7374 |
| 1990's | 4 (10.53) | 18.2507 |
| 2000's | 6 (15.79) | 29.6817 |
| 2010's | 16 (42.11) | 24.3611 |
| 2020's | 7 (18.42) | 2.80 |
| Authors | Studies |
|---|---|
| Yi, O | 1 |
| Lin, Y | 1 |
| Hu, M | 1 |
| Hu, S | 1 |
| Su, Z | 1 |
| Liao, J | 1 |
| Liu, B | 1 |
| Liu, L | 1 |
| Cai, X | 1 |
| Wang, Q | 1 |
| Asenso, J | 1 |
| Xiao, N | 1 |
| Gao, J | 1 |
| Xiao, F | 1 |
| Kuai, J | 1 |
| Wei, W | 1 |
| Wang, C | 1 |
| Pucino, V | 2 |
| Nefla, M | 1 |
| Gauthier, V | 1 |
| Alsaleh, G | 1 |
| Clayton, SA | 1 |
| Marshall, J | 1 |
| Filer, A | 1 |
| Clark, AR | 1 |
| Raza, K | 1 |
| Buckley, CD | 1 |
| Rodríguez-Muguruza, S | 1 |
| Altuna-Coy, A | 1 |
| Arreaza-Gil, V | 1 |
| Mendieta-Homs, M | 1 |
| Castro-Oreiro, S | 1 |
| Poveda-Elices, MJ | 1 |
| Del Castillo-Piñol, N | 1 |
| Fontova-Garrofé, R | 1 |
| Chacón, MR | 1 |
| Mueller, C | 1 |
| Lin, JC | 1 |
| Thannickal, HH | 1 |
| Daredia, A | 1 |
| Denney, TS | 1 |
| Beyers, R | 1 |
| Younger, JW | 1 |
| Souto-Carneiro, M | 1 |
| Tóth, L | 1 |
| Behnisch, R | 1 |
| Urbach, K | 1 |
| Klika, KD | 1 |
| Carvalho, RA | 1 |
| Lorenz, HM | 1 |
| Neveu, MA | 1 |
| Beziere, N | 1 |
| Daniels, R | 1 |
| Bouzin, C | 1 |
| Comment, A | 1 |
| Schwenck, J | 1 |
| Fuchs, K | 1 |
| Kneilling, M | 1 |
| Pichler, BJ | 1 |
| Schmid, AM | 1 |
| Zhao, J | 1 |
| Zhang, X | 2 |
| Sun, X | 1 |
| Zhao, M | 1 |
| Yu, C | 1 |
| Lee, RJ | 1 |
| Sun, F | 1 |
| Zhou, Y | 1 |
| Li, Y | 1 |
| Teng, L | 1 |
| Yang, Z | 1 |
| Matteson, EL | 1 |
| Goronzy, JJ | 1 |
| Weyand, CM | 1 |
| Yang, XY | 1 |
| Zheng, KD | 1 |
| Lin, K | 1 |
| Zheng, G | 1 |
| Zou, H | 1 |
| Wang, JM | 1 |
| Lin, YY | 1 |
| Chuka, CM | 1 |
| Ge, RS | 1 |
| Zhai, W | 1 |
| Wang, JG | 1 |
| Haas, R | 1 |
| Smith, J | 1 |
| Rocher-Ros, V | 1 |
| Nadkarni, S | 1 |
| Montero-Melendez, T | 1 |
| D'Acquisto, F | 1 |
| Bland, EJ | 1 |
| Bombardieri, M | 2 |
| Pitzalis, C | 2 |
| Perretti, M | 1 |
| Marelli-Berg, FM | 1 |
| Mauro, C | 2 |
| He, J | 1 |
| Li, H | 1 |
| Liu, C | 1 |
| Wang, G | 1 |
| Ge, L | 1 |
| Ma, S | 1 |
| Huang, L | 1 |
| Yan, S | 1 |
| Xu, X | 1 |
| Fujii, W | 1 |
| Kawahito, Y | 1 |
| Nagahara, H | 1 |
| Kukida, Y | 1 |
| Seno, T | 1 |
| Yamamoto, A | 1 |
| Kohno, M | 1 |
| Oda, R | 1 |
| Taniguchi, D | 1 |
| Fujiwara, H | 1 |
| Ejima, A | 1 |
| Kishida, T | 1 |
| Mazda, O | 1 |
| Ashihara, E | 1 |
| Biniecka, M | 1 |
| Canavan, M | 1 |
| McGarry, T | 1 |
| Gao, W | 1 |
| McCormick, J | 1 |
| Cregan, S | 1 |
| Gallagher, L | 1 |
| Smith, T | 1 |
| Phelan, JJ | 1 |
| Ryan, J | 1 |
| O'Sullivan, J | 1 |
| Ng, CT | 1 |
| Veale, DJ | 1 |
| Fearon, U | 1 |
| Sonomoto, K | 1 |
| Yamaoka, K | 1 |
| Kaneko, H | 1 |
| Yamagata, K | 1 |
| Sakata, K | 1 |
| Kondo, M | 1 |
| Zenke, Y | 1 |
| Sabanai, K | 1 |
| Nakayamada, S | 1 |
| Sakai, A | 1 |
| Tanaka, Y | 1 |
| Tang, Q | 1 |
| Cui, J | 1 |
| Tian, Z | 1 |
| Sun, J | 1 |
| Wang, Z | 1 |
| Chang, S | 1 |
| Zhu, S | 1 |
| Belova, SV | 1 |
| Kariakina, EV | 1 |
| Hitchon, CA | 1 |
| El-Gabalawy, HS | 1 |
| Bezabeh, T | 1 |
| Chang, X | 1 |
| Wei, C | 1 |
| Scheinman, RI | 1 |
| Trivedi, R | 1 |
| Vermillion, S | 1 |
| Kompella, UB | 1 |
| Tiihonen, RP | 1 |
| Skyttä, ET | 2 |
| Kaarela, K | 1 |
| Ikävalko, M | 2 |
| Belt, EA | 2 |
| te Boekhorst, BC | 1 |
| Jensen, LB | 1 |
| Colombo, S | 1 |
| Varkouhi, AK | 1 |
| Schiffelers, RM | 1 |
| Lammers, T | 1 |
| Storm, G | 1 |
| Nielsen, HM | 1 |
| Strijkers, GJ | 1 |
| Foged, C | 1 |
| Nicolay, K | 1 |
| Park, JS | 2 |
| Yang, HN | 1 |
| Jeon, SY | 1 |
| Woo, DG | 1 |
| Kim, MS | 1 |
| Park, KH | 1 |
| Présumey, J | 1 |
| Salzano, G | 1 |
| Courties, G | 1 |
| Shires, M | 1 |
| Ponchel, F | 1 |
| Jorgensen, C | 1 |
| Apparailly, F | 1 |
| De Rosa, G | 1 |
| KALLIOMAKI, JL | 1 |
| PULKKINEN, M | 1 |
| SAVOLA, P | 1 |
| Mavridis, AK | 1 |
| Drosos, AA | 1 |
| Tsolas, O | 1 |
| Moutsopoulos, HM | 1 |
| Gobelet, C | 1 |
| Gerster, JC | 1 |
| Brothers, GB | 1 |
| Hadler, NM | 1 |
| Naughton, D | 1 |
| Whelan, M | 1 |
| Smith, EC | 1 |
| Williams, R | 1 |
| Blake, DR | 1 |
| Grootveld, M | 1 |
| Voche, P | 1 |
| Merle, M | 1 |
| Membre, H | 1 |
| Fockens, W | 1 |
| D'Souza, M | 1 |
| DeSouza, P | 1 |
| Meshitsuka, S | 1 |
| Yamazaki, E | 1 |
| Inoue, M | 1 |
| Hagino, H | 1 |
| Teshima, R | 1 |
| Yamamoto, K | 1 |
| Voutilainen, N | 1 |
| Pätiälä, H | 1 |
| Juutilainen, T | 1 |
| Partio, EK | 1 |
| Rokkanen, P | 1 |
| Adcocks, C | 1 |
| Collin, P | 1 |
| Buttle, DJ | 1 |
| Kim, WU | 1 |
| Lee, WK | 1 |
| Ryoo, JW | 1 |
| Kim, SH | 1 |
| Kim, J | 1 |
| Youn, J | 1 |
| Min, SY | 1 |
| Bae, EY | 1 |
| Hwang, SY | 1 |
| Park, SH | 1 |
| Cho, CS | 1 |
| Kim, HY | 1 |
| Evanchick, CE | 1 |
| Davis, DE | 1 |
| Harrington, TM | 1 |
5 reviews available for lactic acid and Rheumatoid Arthritis
| Article | Year |
|---|---|
Lactate metabolism in rheumatoid arthritis: Pathogenic mechanisms and therapeutic intervention with natural compounds.
Topics: Arthritis, Rheumatoid; Fibroblasts; Humans; Inflammation; Lactic Acid; Synovial Membrane | 2022 |
Lactic Acid Regulation: A Potential Therapeutic Option in Rheumatoid Arthritis.
Topics: Animals; Arthritis, Rheumatoid; Interleukins; Joints; Lactic Acid; Synoviocytes | 2022 |
T-cell metabolism in autoimmune disease.
Topics: Adenosine Triphosphate; Arthritis, Rheumatoid; Autoimmune Diseases; Humans; Lactic Acid; Lupus Eryth | 2015 |
Lactate at the crossroads of metabolism, inflammation, and autoimmunity.
Topics: Animals; Arthritis, Rheumatoid; Autoimmune Diseases; Autoimmunity; Energy Metabolism; Humans; Immune | 2017 |
Glycolysis and rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Autoantigens; Cell Differentiation; Cell Proliferation; Fructose-Bisphosphate | 2011 |
1 trial available for lactic acid and Rheumatoid Arthritis
| Article | Year |
|---|---|
Reconstruction of the trapeziometacarpal joint in inflammatory joint disease using interposition of autologous tendon or poly-L-D-lactic acid implants: a prospective clinical trial.
Topics: Absorbable Implants; Adult; Aged; Arthritis, Rheumatoid; Arthroplasty; Bioprosthesis; Carpometacarpa | 2012 |
32 other studies available for lactic acid and Rheumatoid Arthritis
| Article | Year |
|---|---|
Differential effect of lactate on synovial fibroblast and macrophage effector functions.
Topics: Arthritis, Rheumatoid; Fibroblasts; Humans; Inflammation; Interleukin-6; Lactic Acid | 2023 |
A serum metabolic biomarker panel for early rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Biomarkers; Glyceric Acids; Humans; Lactic Acid | 2023 |
No evidence of abnormal metabolic or inflammatory activity in the brains of patients with rheumatoid arthritis: results from a preliminary study using whole-brain magnetic resonance spectroscopic imaging (MRSI).
Topics: Adult; Arthritis, Rheumatoid; Brain; Case-Control Studies; Choline; Female; Humans; Inositol; Lactic | 2020 |
Differences in the serum metabolome and lipidome identify potential biomarkers for seronegative rheumatoid arthritis versus psoriatic arthritis.
Topics: Acetates; Adult; Aged; Aged, 80 and over; Alanine; Amino Acids; Arthritis, Psoriatic; Arthritis, Rhe | 2020 |
Lactate Production Precedes Inflammatory Cell Recruitment in Arthritic Ankles: an Imaging Study.
Topics: Animals; Ankle; Arthritis, Rheumatoid; Carbon Isotopes; Female; Fluorine; Inflammation; Joints; Lact | 2020 |
Dual-functional lipid polymeric hybrid pH-responsive nanoparticles decorated with cell penetrating peptide and folate for therapy against rheumatoid arthritis.
Topics: Animals; Antirheumatic Agents; Arginine; Arthritis, Experimental; Arthritis, Rheumatoid; Cell-Penetr | 2018 |
Energy Metabolism Disorder as a Contributing Factor of Rheumatoid Arthritis: A Comparative Proteomic and Metabolomic Study.
Topics: Adult; Arthritis, Rheumatoid; Biomarkers; Energy Metabolism; Female; Glucose; Humans; Knee Joint; La | 2015 |
Lactate Regulates Metabolic and Pro-inflammatory Circuits in Control of T Cell Migration and Effector Functions.
Topics: Animals; Arthritis, Rheumatoid; CD4-Positive T-Lymphocytes; Cell Movement; Chemokines; Female; Glyco | 2015 |
Formulation and evaluation of poly(lactic-co-glycolic acid) microspheres loaded with an altered collagen type II peptide for the treatment of rheumatoid arthritis.
Topics: Animals; Arthritis, Rheumatoid; Chromatography, High Pressure Liquid; Collagen Type II; Drug Deliver | 2015 |
Monocarboxylate transporter 4, associated with the acidification of synovial fluid, is a novel therapeutic target for inflammatory arthritis.
Topics: Aged; Animals; Apoptosis; Arthritis, Experimental; Arthritis, Rheumatoid; Cartilage, Articular; Fema | 2015 |
Dysregulated bioenergetics: a key regulator of joint inflammation.
Topics: Amino Acids, Dicarboxylic; Arthritis, Rheumatoid; Cell Movement; Cells, Cultured; Cytokines; DNA, Mi | 2016 |
Spontaneous Differentiation of Human Mesenchymal Stem Cells on Poly-Lactic-Co-Glycolic Acid Nano-Fiber Scaffold.
Topics: Arthritis, Rheumatoid; Biocompatible Materials; Blotting, Western; Case-Control Studies; Cell Differ | 2016 |
Oxygen and indocyanine green loaded phase-transition nanoparticle-mediated photo-sonodynamic cytotoxic effects on rheumatoid arthritis fibroblast-like synoviocytes.
Topics: Apoptosis; Arthritis, Rheumatoid; Biocompatible Materials; Cell Survival; Drug Delivery Systems; Fib | 2017 |
[Condition of oxidation homeostasis and possibility of its correction in experimental rheumatoid arthritis].
Topics: Animals; Arthritis, Experimental; Arthritis, Rheumatoid; Ceruloplasmin; Homeostasis; Hydrogen Peroxi | 2008 |
Characterization of synovial tissue from arthritis patients: a proton magnetic resonance spectroscopic investigation.
Topics: Adult; Aged; Aged, 80 and over; Arthritis, Rheumatoid; Case-Control Studies; Choline; Creatine; Fuco | 2009 |
Functionalized STAT1 siRNA nanoparticles regress rheumatoid arthritis in a mouse model.
Topics: Animals; Arthritis, Rheumatoid; Disease Models, Animal; Drug Carriers; Drug Delivery Systems; Drug S | 2011 |
MRI-assessed therapeutic effects of locally administered PLGA nanoparticles loaded with anti-inflammatory siRNA in a murine arthritis model.
Topics: Animals; Arthritis, Experimental; Arthritis, Rheumatoid; Bone Marrow; Cell Line; Drug Carriers; Fatt | 2012 |
The use of anti-COX2 siRNA coated onto PLGA nanoparticles loading dexamethasone in the treatment of rheumatoid arthritis.
Topics: Apoptosis; Arthritis, Rheumatoid; Caspase 3; Cell Line; Cell Survival; Cyclooxygenase 2; Dexamethaso | 2012 |
PLGA microspheres encapsulating siRNA anti-TNFalpha: efficient RNAi-mediated treatment of arthritic joints.
Topics: Animals; Arthritis, Experimental; Arthritis, Rheumatoid; Cell Line; Drug Design; Lactic Acid; Mice; | 2012 |
Lactic acid response to muscular exercise in rheumatoid arthritis.
Topics: Arthritis; Arthritis, Rheumatoid; Exercise; Humans; Lactic Acid; Muscles | 1957 |
One-year results of use of poly-L/D-lactic acid joint scaffolds and bone packing in revision metacarpophalangeal arthroplasty.
Topics: Absorbable Implants; Adult; Aged; Arthritis, Juvenile; Arthritis, Psoriatic; Arthritis, Rheumatoid; | 2007 |
Lactate levels in Brucella arthritis.
Topics: Arthritis; Arthritis, Infectious; Arthritis, Rheumatoid; Brucellosis; Gout; Humans; Lactates; Lactic | 1984 |
Synovial fluid lactate levels in septic and non-septic arthritides.
Topics: Arthritis; Arthritis, Infectious; Arthritis, Reactive; Arthritis, Rheumatoid; Gonorrhea; Hemarthrosi | 1984 |
Diurnal variations in rheumatoid synovial effusions.
Topics: Adult; Arthritis, Rheumatoid; Circadian Rhythm; Female; Glucose; Humans; Hydrogen-Ion Concentration; | 1983 |
An investigation of the abnormal metabolic status of synovial fluid from patients with rheumatoid arthritis by high field proton nuclear magnetic resonance spectroscopy.
Topics: 3-Hydroxybutyric Acid; Adult; Aged; Arthritis, Rheumatoid; Blood Glucose; Chylomicrons; Glucose; Hum | 1993 |
Bioabsorbable rods and pins for fixation of metacarpophalangeal arthrodesis of the thumb.
Topics: Adolescent; Adult; Aged; Animals; Arthritis, Rheumatoid; Arthrodesis; Female; Femur; Follow-Up Studi | 1995 |
Preparation and testing of cyclosporine microsphere and solution formulations in the treatment of polyarthritis in rats.
Topics: Animals; Arthritis, Rheumatoid; Cell Division; Cells, Cultured; Chemistry, Pharmaceutical; Cyclospor | 1998 |
Nuclear magnetic resonance studies of synovial fluids from patients with rheumatoid arthritis and osteoarthritis.
Topics: Alanine; Arthritis, Rheumatoid; Biomarkers; Diagnosis, Differential; Female; Humans; Lactic Acid; Ma | 1999 |
Long-term results of ankle and triple arthrodeses fixed with self-reinforced polylevolactic acid implants in patients with rheumatoid arthritis.
Topics: Absorbable Implants; Adult; Aged; Ankle Joint; Arthritis, Rheumatoid; Arthrodesis; Biocompatible Mat | 2001 |
Catechins from green tea (Camellia sinensis) inhibit bovine and human cartilage proteoglycan and type II collagen degradation in vitro.
Topics: Animals; Arthritis, Rheumatoid; Cartilage; Cartilage, Articular; Catechin; Cattle; Collagen Type II; | 2002 |
Suppression of collagen-induced arthritis by single administration of poly(lactic-co-glycolic acid) nanoparticles entrapping type II collagen: a novel treatment strategy for induction of oral tolerance.
Topics: Animals; Arthritis, Experimental; Arthritis, Rheumatoid; Autoimmunity; Biocompatible Materials; Catt | 2002 |
Septic arthritis. Clinical approach to the 'hot joint'.
Topics: Adolescent; Adult; Anti-Bacterial Agents; Arthritis, Infectious; Arthritis, Rheumatoid; Child; Diagn | 1986 |