bupivacaine has been researched along with Rheumatoid Arthritis in 16 studies
Bupivacaine: A widely used local anesthetic agent.
1-butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide : A piperidinecarboxamide obtained by formal condensation of the carboxy group of N-butylpipecolic acid with the amino group of 2,6-dimethylaniline.
bupivacaine : A racemate composed of equimolar amounts of dextrobupivacaine and levobupivacaine. Used (in the form of its hydrochloride hydrate) as a local anaesthetic.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The action of adrenaline on the pharmacokinetics of bupivacaine has been tested during two successive interscalene brachial plexus blocks in 10 patients with rheumatoid arthritis." | 7.67 | Bupivacaine with and without adrenaline in interscalene brachial plexus blockade. Studies in patients with rheumatoid arthritis. ( Lindberg, RL; Pihlajamäki, KK, 1987) |
| "We aim to evaluate the efficacy of intraarticular triamcinolone injection of the AAJ on neck pain and disability." | 5.30 | Efficacy of Atlantoaxial Joint Glucocorticoid Injection in Patients with Rheumatoid Arthritis: A Randomized Trial. ( Aljohi, AS; Elawamy, AM; Hasan, RA; Hassanein, MM; Hetta, DF; Mohammed, NAA; Seifeldein, GS, 2019) |
| "The pain relief provided by intra-articular injection of morphine plus bupivacaine after total knee arthroplasty (TKA) plus partial synovectomy in patients with rheumatoid arthritis was compared with pain relief after TKA alone in patients with osteoarthritis." | 3.71 | The efficacy of intra-articular analgesia after total knee arthroplasty in patients with rheumatoid arthritis and in patients with osteoarthritis. ( Hirose, K; Ishii, S; Sakahashi, H; Sato, E; Tanaka, N, 2001) |
| "Thirty-five adult patients with rheumatoid arthritis received for 36 interscalene brachial plexus blocks a standard dose of bupivacaine 200 mg, regardless of the weight (range 39." | 3.68 | Inverse correlation between the peak venous serum concentration of bupivacaine and the weight of the patient during interscalene brachial plexus block. ( Pihlajamäki, KK, 1991) |
| "The action of adrenaline on the pharmacokinetics of bupivacaine has been tested during two successive interscalene brachial plexus blocks in 10 patients with rheumatoid arthritis." | 3.67 | Bupivacaine with and without adrenaline in interscalene brachial plexus blockade. Studies in patients with rheumatoid arthritis. ( Lindberg, RL; Pihlajamäki, KK, 1987) |
| " We hypothesized that BMI-related inverse dosing of plain bupivacaine according to low, normal, and high BMI would result in no difference in block extent." | 1.37 | The effect of body mass index on the spread of spinal block in patients with rheumatoid arthritis. ( Kuusniemi, KS; Leino, KA; Pälve, HK; Tiusanen, HT; Tuppurainen, TT, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (25.00) | 18.7374 |
| 1990's | 3 (18.75) | 18.2507 |
| 2000's | 5 (31.25) | 29.6817 |
| 2010's | 4 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hetta, DF | 1 |
| Elawamy, AM | 1 |
| Hassanein, MM | 1 |
| Aljohi, AS | 1 |
| Hasan, RA | 1 |
| Mohammed, NAA | 1 |
| Seifeldein, GS | 1 |
| Leino, KA | 2 |
| Kuusniemi, KS | 2 |
| Pälve, HK | 2 |
| Korpelainen, JT | 1 |
| Tiusanen, HT | 2 |
| Tuppurainen, TT | 2 |
| Dobie, I | 1 |
| Bennett, D | 1 |
| Spence, DJ | 1 |
| Murray, JM | 1 |
| Beverland, DE | 1 |
| Shanahan, EM | 1 |
| Ahern, M | 1 |
| Smith, M | 1 |
| Wetherall, M | 1 |
| Bresnihan, B | 1 |
| FitzGerald, O | 1 |
| Avery, JK | 1 |
| Alfa, JA | 1 |
| Bamgbade, OA | 1 |
| Lindberg, RL | 2 |
| Pihlajamäki, KK | 3 |
| Gado, K | 1 |
| Emery, P | 2 |
| Kirkham, B | 1 |
| Portek, I | 1 |
| Lee, CS | 1 |
| Stavros, B | 1 |
| Lenarczyk, A | 1 |
| Lassere, M | 1 |
| Edmonds, J | 1 |
| Tanaka, N | 1 |
| Sakahashi, H | 1 |
| Sato, E | 1 |
| Hirose, K | 1 |
| Ishii, S | 1 |
| DeWeese, FT | 1 |
| Akbari, Z | 1 |
| Carline, E | 1 |
| Bowman, S | 1 |
| Wedderburn, L | 1 |
| Grahame, R | 1 |
| Wulf, H | 1 |
| Winckler, K | 1 |
| Denzer, D | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Ultrasound-guided Pericapsular Nerve Group (PENG) Block vs. Intraoperative Local Anesthetic Infiltration (ILAI) for Total Hip Arthroplasty (THA): a Single Center, Non-inferiority Randomized Control Trial.[NCT05898581] | 40 participants (Anticipated) | Interventional | 2024-01-01 | Not yet recruiting | |||
| Suprascapular Nerve Block Versus Intraarticular Steroid Injection in Hemiplegic Shoulder Pain: A Randomized Double Blinded Control Trial[NCT04128605] | 86 participants (Anticipated) | Interventional | 2019-07-11 | Recruiting | |||
| Comparison of Efficacy and Safety of Two Different Ultrasound-Guided Suprascapular Nerve Block Techniques in Chronic Shoulder Pain: A Prospective Double-Blinded Randomized Controlled Study[NCT04938037] | 80 participants (Anticipated) | Interventional | 2021-06-01 | Recruiting | |||
| The Role of Intra-Operative Intracapsular Blocks in Post-Operative Pain Management Following Total Knee Arthroplasty: A Double-Blinded Randomized Controlled Trial[NCT00620828] | Phase 4 | 67 participants (Actual) | Interventional | 2007-05-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Ambulation distance walked by participants 24-hours post-operatively (NCT00620828)
Timeframe: 24 hours post-op
| Intervention | Feet (Median) |
|---|---|
| Block Group | 38.4 |
| Control Group | 26.4 |
Participants were asked to rate their pain on a scale of 0 to 10 at all time intervals up to 24 hours post-injection. Scores were organized into the following categories: 3 or less (mild pain), 4 to 6 (moderate pain), 7 or higher (severe pain). (NCT00620828)
Timeframe: Post-anesthesia care unit (PACU), 4 hours, 8 hours, 12 hours and 24 hours post-injection
| Intervention | units on a scale (Mean) | ||||
|---|---|---|---|---|---|
| PACU | 4 hours | 8 hours | 12 hours | 24 hours | |
| Block Group | 0.67 | 2.5 | 3.8 | 3.2 | 3.9 |
| Control Group | 1.6 | 3.6 | 4.9 | 3.9 | 4.9 |
Straight Leg Raise (SLR): number of people that can perform a SLR at designated intervals (NCT00620828)
Timeframe: 4 hours, 8 hours, 12 hours and 24 hours post-op
| Intervention | participants (Number) | |||
|---|---|---|---|---|
| SLR 4 hrs | SLR 8 hrs | SLR 12 hrs | SLR 24 hrs | |
| Block Group | 4 | 13 | 12 | 13 |
| Control Group | 5 | 5 | 5 | 6 |
Knee extension and knee flexion measured at 24-hours post-operatively for patient cohort (NCT00620828)
Timeframe: 24 hours post-op
| Intervention | degrees (Mean) | |
|---|---|---|
| Knee extension | Knee flexion | |
| Block Group | 7.8 | 71.5 |
| Control Group | 7.0 | 69.6 |
The PCA total dose at the 4-hour, 8-hour, 12-hour and 24-hour post-operative time points. (NCT00620828)
Timeframe: 4 hours to 24 hours post-op
| Intervention | micrograms (Mean) | |||
|---|---|---|---|---|
| 4 hours | 8 hours | 12 hours | 24 hours | |
| Block Group | 22.4 | 95.6 | 173.4 | 418.5 |
| Control Group | 43.7 | 126.6 | 205.6 | 292.2 |
5 trials available for bupivacaine and Rheumatoid Arthritis
| Article | Year |
|---|---|
Efficacy of Atlantoaxial Joint Glucocorticoid Injection in Patients with Rheumatoid Arthritis: A Randomized Trial.
Topics: Adult; Arthritis, Rheumatoid; Atlanto-Axial Joint; Bupivacaine; Female; Glucocorticoids; Humans; Inj | 2019 |
Periarticular local anesthesia does not improve pain or mobility after THA.
Topics: Adrenergic Agonists; Aged; Analgesics, Opioid; Anesthetics, Local; Arthritis, Rheumatoid; Arthroplas | 2012 |
Suprascapular nerve block (using bupivacaine and methylprednisolone acetate) in chronic shoulder pain.
Topics: Adult; Aged; Aged, 80 and over; Anesthetics, Local; Anti-Inflammatory Agents; Arthritis, Rheumatoid; | 2003 |
Suprascapular nerve block (using bupivacaine and methylprednisolone acetate) in chronic shoulder pain.
Topics: Adult; Aged; Aged, 80 and over; Anesthetics, Local; Anti-Inflammatory Agents; Arthritis, Rheumatoid; | 2003 |
Suprascapular nerve block (using bupivacaine and methylprednisolone acetate) in chronic shoulder pain.
Topics: Adult; Aged; Aged, 80 and over; Anesthetics, Local; Anti-Inflammatory Agents; Arthritis, Rheumatoid; | 2003 |
Suprascapular nerve block (using bupivacaine and methylprednisolone acetate) in chronic shoulder pain.
Topics: Adult; Aged; Aged, 80 and over; Anesthetics, Local; Anti-Inflammatory Agents; Arthritis, Rheumatoid; | 2003 |
Modified suprascapular nerve block with bupivacaine alone effectively controls chronic shoulder pain in patients with rheumatoid arthritis.
Topics: Adult; Aged; Arthritis, Rheumatoid; Bupivacaine; Chronic Disease; Double-Blind Method; Female; Human | 1993 |
Suprascapular nerve block for chronic shoulder pain in rheumatoid arthritis.
Topics: Aged; Aged, 80 and over; Arthritis, Rheumatoid; Bupivacaine; Female; Humans; Lidocaine; Male; Methyl | 1989 |
11 other studies available for bupivacaine and Rheumatoid Arthritis
| Article | Year |
|---|---|
Spread of spinal block in patients with rheumatoid arthritis.
Topics: Anesthesia, Spinal; Anesthetics, Local; Arthritis, Rheumatoid; Body Mass Index; Bupivacaine; Cerebro | 2010 |
The effect of body mass index on the spread of spinal block in patients with rheumatoid arthritis.
Topics: Adult; Aged; Anesthesia, Spinal; Arthritis, Rheumatoid; Body Mass Index; Bupivacaine; Female; Humans | 2011 |
Technique in question.
Topics: Adjuvants, Anesthesia; Anesthesiology; Anesthetics, Intravenous; Anesthetics, Local; Arthritis, Rheu | 2006 |
Acute myoclonus following spinal anaesthesia.
Topics: Acute Disease; Analgesics, Opioid; Anesthesia Recovery Period; Anesthesia, Spinal; Anesthetics, Intr | 2008 |
High-performance liquid chromatographic determination of bupivacaine in human serum.
Topics: Adult; Aged; Anesthesia, Epidural; Anesthesia, Spinal; Arthritis, Rheumatoid; Bupivacaine; Chromatog | 1984 |
Intraarticular variability of synovial membrane histology, immunohistology, and cytokine mRNA expression in patients with rheumatoid arthritis.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anesthetics, Local; Antirheumatic Agents; Arthritis, Rhe | 1999 |
The efficacy of intra-articular analgesia after total knee arthroplasty in patients with rheumatoid arthritis and in patients with osteoarthritis.
Topics: Analgesia; Analgesics, Opioid; Anesthetics, Local; Arthritis, Rheumatoid; Arthroplasty, Replacement, | 2001 |
Pain control after knee arthroplasty: intraarticular versus epidural anesthesia.
Topics: Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Anesthesia, Epidural; Anesthetics, Lo | 2001 |
Inverse correlation between the peak venous serum concentration of bupivacaine and the weight of the patient during interscalene brachial plexus block.
Topics: Adult; Aged; Aged, 80 and over; Arthritis, Rheumatoid; Body Weight; Brachial Plexus; Bupivacaine; Fe | 1991 |
Plasma concentrations of alpha-1-acid glycoprotein following operations and its effect on the plasma protein binding of bupivacaine.
Topics: Arthritis, Rheumatoid; Bupivacaine; Hip Prosthesis; Humans; Middle Aged; Orosomucoid; Osteoarthritis | 1989 |
Bupivacaine with and without adrenaline in interscalene brachial plexus blockade. Studies in patients with rheumatoid arthritis.
Topics: Adult; Aged; Arthritis, Rheumatoid; Brachial Plexus; Bupivacaine; Epinephrine; Female; Hemodynamics; | 1987 |