oxyphenbutazone has been researched along with Rheumatoid Arthritis in 73 studies
Oxyphenbutazone: A non-steroidal anti-inflammatory drug. Oxyphenbutazone eyedrops have been used abroad in the management of postoperative ocular inflammation, superficial eye injuries, and episcleritis. (From AMA, Drug Evaluations Annual, 1994, p2000) It had been used by mouth in rheumatic disorders such as ankylosing spondylitis, osteoarthritis, and rheumatoid arthritis but such use is no longer considered justified owing to the risk of severe hematological adverse effects. (From Martindale, The Extra Pharmacopoeia, 30th ed, p27)
oxyphenbutazone : A metabolite of phenylbutazone obtained by hydroxylation at position 4 of one of the phenyl rings. Commonly used (as its hydrate) to treat pain, swelling and stiffness associated with arthritis and gout, it was withdrawn from the market 1984 following association with blood dyscrasis and Stevens-Johnson syndrome.
Excerpt | Relevance | Reference |
---|---|---|
"The antirheumatic effect of pirfenidone was compared with a positive control drug, oxyphenbutazone which is used in patients suffering from rheumatoid arthritis, in a double blind clinical trial in humans." | 5.11 | Antirheumatic effect of pirfenidone in a double blind clinical pilot trial in humans. ( Giri, SN; Margolin, SB; Pesce, E; Struma, E, 2004) |
" She subsequently developed agranulocytosis and cholestatic hepatitis as an adverse reaction to these drugs, later identified as oxyphenbutazone and diazepam." | 3.67 | Agranulocytosis and hepatitis as a result of Mexican drug therapy. ( Jacknowitz, AI; Walker, BK, 1984) |
" Salicylates are preferred to adrenocortical steroids in the treatment of the ordinary patient with acute rheumatic fever." | 3.64 | NONSPECIFIC ANTI-INFLAMMATORY AGENTS. SOME NOTES ON THEIR PRACTICAL APPLICATION, ESPECIALLY IN RHEUMATIC DISORDERS. ( BOLAND, EW, 1964) |
"Treatment of rheumatoid arthritis is often frustrating for patient and physician alike because of its chronic nature and our lack of knowledge about precise cause." | 2.35 | Treatment of rheumatoid arthritis: a review including newer and experimental anti-inflammatory agents. ( Kaye, RL; Pemberton, RE, 1976) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 72 (98.63) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 1 (1.37) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
GJERDSJO, A | 1 |
MEANOCK, RI | 1 |
LEWIS-FANING, E | 1 |
JARLOV, NV | 1 |
SMYTH, CJ | 2 |
CONCONI, F | 1 |
MATTIOLI, G | 1 |
VIRKKUNEN, M | 1 |
ONEL, D | 1 |
IMRE, I | 1 |
JOHANSEN, PE | 1 |
ROSENBAUM, ER | 1 |
SCHWARZ, GR | 1 |
GOTTI, D | 1 |
SANTOPADRE, I | 1 |
SPERLING, IL | 2 |
YANO, Y | 1 |
TOKIEDA, M | 1 |
MASON, RM | 2 |
BOLAND, EW | 1 |
HART, FD | 3 |
BOARDMAN, PL | 1 |
SVANTESSON, H | 1 |
CASTAGNA, AN | 1 |
ROTHERMICH, NO | 1 |
FORD, DK | 1 |
FORMAN, O | 1 |
Pesce, E | 1 |
Struma, E | 1 |
Giri, SN | 1 |
Margolin, SB | 1 |
Jacknowitz, AI | 1 |
Walker, BK | 1 |
Loizzi, P | 1 |
Pipitone, V | 1 |
Bignamini, AA | 1 |
Fasching, U | 1 |
Eberl, R | 2 |
Ring, EF | 1 |
Fowler, PD | 1 |
Faragher, EB | 1 |
Franke, M | 1 |
Manz, G | 1 |
Kaye, RL | 1 |
Pemberton, RE | 1 |
Maibach, E | 1 |
Roberts, ME | 1 |
Wright, V | 1 |
Hill, AG | 1 |
Mehra, AC | 1 |
Klein, G | 1 |
Wottawa, A | 1 |
Mason, DI | 1 |
Brooks, PM | 1 |
Buchanan, WW | 1 |
Binns, TB | 1 |
Vidal Ferrandis, J | 1 |
Menchón Galiana, M | 1 |
López Dasí, JL | 1 |
López Prats, JL | 1 |
Barth, WF | 1 |
Mizushima, Y | 1 |
Healey, LA | 1 |
Cosh, JA | 1 |
Watson, PG | 1 |
Lobascher, D | 1 |
Stenlake, JB | 2 |
Williams, WD | 2 |
Davidson, AG | 2 |
Downie, W | 1 |
Whaley, K | 1 |
Downie, WW | 1 |
Ehrlich, GE | 1 |
Siegmeth, W | 1 |
Herkner, W | 1 |
Sariols, M | 1 |
Tausch, G | 1 |
Tuschl, P | 1 |
Dunky, A | 1 |
Sell, G | 1 |
Widhammer, M | 1 |
Frenger, W | 1 |
Medenica, R | 1 |
Abele, I | 1 |
Dobryk, R | 1 |
Kuzmanovic, I | 1 |
Junet, R | 1 |
Mikkelsen, OA | 1 |
Shiokawa, Y | 1 |
Matsumoto, J | 2 |
Mathies, H | 3 |
Riedel, R | 1 |
Schoetensack, W | 1 |
Pérez Gil, L | 1 |
Beltrán Gutiérrez, J | 1 |
Fernández del Vallado, P | 1 |
Gijón Baños, J | 1 |
Abe, T | 1 |
Gomi, J | 1 |
Honma, M | 1 |
Kageyama, T | 1 |
Katsu, M | 1 |
Schmied, P | 1 |
Van Rossum, P | 1 |
Fallet, GH | 1 |
Tagiaferro, E | 1 |
Pilewski, RM | 1 |
Ellis, LD | 1 |
Sapira, JD | 1 |
Mark, R | 1 |
Bossa, G | 1 |
Giordano, M | 1 |
David-Chaussé, J | 1 |
David-Chaussé, F | 1 |
Picot, C | 1 |
Laporte, G | 1 |
Lagoarde, J | 1 |
Dehais, J | 1 |
Husmann, F | 1 |
Deller, DJ | 1 |
Urban, E | 1 |
Ibbotson, RN | 1 |
Horwood, J | 1 |
Milazzo, S | 1 |
Robson, HN | 1 |
Vitaus, M | 1 |
Jiménez Roldán, A | 1 |
De Usobiaga, JL | 1 |
Borrachero, J | 1 |
Carrasco, J | 1 |
Ibarra, J | 1 |
4 reviews available for oxyphenbutazone and Rheumatoid Arthritis
Article | Year |
---|---|
Thermography and rheumatic diseases.
Topics: Adrenocorticotropic Hormone; Arthritis; Arthritis, Juvenile; Arthritis, Rheumatoid; Body Temperature | 1975 |
Treatment of rheumatoid arthritis: a review including newer and experimental anti-inflammatory agents.
Topics: Activities of Daily Living; Adrenal Cortex Hormones; Anti-Inflammatory Agents; Antimalarials; Arthri | 1976 |
Therapy of rheumatoid arthritis. A pyramidal plan.
Topics: Arthritis, Rheumatoid; Chloroquine; Cyclophosphamide; Glucocorticoids; Gold; Hospitalization; Hot Te | 1972 |
[The conservative treatment of chronic inflammatory rheumatism].
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Analgesics; Anti-Inflammatory Agents; Antimalarials; Art | 1969 |
12 trials available for oxyphenbutazone and Rheumatoid Arthritis
Article | Year |
---|---|
Antirheumatic effect of pirfenidone in a double blind clinical pilot trial in humans.
Topics: Adult; Antirheumatic Agents; Arthritis, Rheumatoid; Chi-Square Distribution; Double-Blind Method; Fe | 2004 |
Double-blind clinical trial of protacine versus oxyphenbutazone in rheumatic disorders.
Topics: Adult; Aged; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoi | 1980 |
[Sulindac: Clinical test of a new antiinflammatory agent in rheumatoid arthritis (author's transl)].
Topics: Adult; Aged; Alopecia; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Benzylidene Compoun | 1976 |
Comparison of fenoprofen and oxyphenbutazone in patients with rheumatoid arthritis.
Topics: Adult; Aged; Alkaline Phosphatase; Arthritis, Rheumatoid; Blood Sedimentation; Clinical Trials as To | 1977 |
European experiences with tolmetin in the treatment of rheumatic diseases.
Topics: Aged; Arthritis, Rheumatoid; Clinical Trials as Topic; Female; Humans; Indomethacin; Male; Middle Ag | 1976 |
The diagnosis and management of episcleritis and scleritis.
Topics: Arteritis; Arthritis, Rheumatoid; Behcet Syndrome; Clinical Trials as Topic; Deafness; Eczema; Epine | 1965 |
[Experiences with a new combination drug (Realin) in the treatment of acute rheumatic conditions].
Topics: Acute Disease; Adult; Aged; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Drug Combinations; Drug | 1974 |
[Double-blind clinical study with placebo versus bumadizone-Ca in 113 patients with rheumatism].
Topics: Adult; Aged; Animals; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Blood Sedimentation; Body Tem | 1973 |
Tanderil in surgery of rheumatic diseases. A double blind trial at dorsal synovectomy of the wrist joint.
Topics: Adolescent; Adult; Aged; Arthritis, Rheumatoid; Child; Clinical Trials as Topic; Edema; Female; Huma | 1972 |
[Clinical test of B64114 for rheumatoid arthritis].
Topics: Arthritis, Rheumatoid; Clinical Trials as Topic; Evaluation Studies as Topic; Female; Humans; Male; | 1972 |
[Double-blind study using flufenamic acid (F.I. 440) and oxyphenylbutazone in rheumatoid arthritis and ankylosing spine].
Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Clinical Trials as Topic; Flufenamic Acid; Fluorine | 1968 |
[Clinical evaluation of the drug in chronic articular rheumatism--multi-organization cooperative studies of oxyphenbutazone based on the 7-day variability study].
Topics: Arthritis, Rheumatoid; Chronic Disease; Clinical Trials as Topic; Evaluation Studies as Topic; Human | 1971 |
57 other studies available for oxyphenbutazone and Rheumatoid Arthritis
Article | Year |
---|---|
[Clinical experience with hydroxyphenylbutazone].
Topics: Arthritis; Arthritis, Rheumatoid; Humans; Oxyphenbutazone; Phenylbutazone | 1961 |
A controlled trial of phenylbutazone, oxyphenbutazone, and a placebo in the treatment of rheumatoid arthritis.
Topics: Arthritis; Arthritis, Rheumatoid; Oxyphenbutazone; Phenylbutazone | 1961 |
Tanderil (G 27202) in the treatment of the rheumatic diseases.
Topics: Arthritis; Arthritis, Rheumatoid; Oxyphenbutazone; Phenylbutazone; Rheumatic Diseases | 1960 |
A method of drug evaluation in rheumatoid arthritis: results with phenylbutazone, oxyphenylbutazone, cortisone, and prednisone.
Topics: Arthritis, Rheumatoid; Cortisone; Drug Evaluation; Oxyphenbutazone; Phenylbutazone; Prednisone | 1960 |
[Stability of the serum glutamic oxalacetic and glutamic pyruvic transaminases in the course of treatment with oxyphenylbutazone].
Topics: Alanine Transaminase; Arthritis; Arthritis, Rheumatoid; Humans; Oxyphenbutazone; Phenylbutazone; Tra | 1962 |
[p-Hydroxyphenylbutazone in the treatment of rheumatoid arthritis].
Topics: Arthritis; Arthritis, Rheumatoid; Humans; Oxyphenbutazone; Phenylbutazone | 1962 |
[On Tanderil and the results of its clinical use].
Topics: Arthritis, Rheumatoid; Humans; Joint Diseases; Osteoarthritis; Oxyphenbutazone; Phenylbutazone; Spon | 1962 |
[A case of agranulocytosis during Tanderil treatment].
Topics: Agranulocytosis; Analgesics; Analgesics, Non-Narcotic; Antipyretics; Arthritis; Arthritis, Rheumatoi | 1962 |
Long-term evaluation of oxyphenbutazone in rheumatic disorders.
Topics: Arthritis; Arthritis, Rheumatoid; Bursitis; Humans; Oxyphenbutazone; Phenylbutazone; Rheumatic Disea | 1962 |
[CLINICAL DATA ON THE USE OF A NEW SYNTHETIC ANTI-DYSREACTIVE AGENT IN THE PEDIATRIC FIELD].
Topics: Arthritis; Arthritis, Rheumatoid; Asthma; Bronchitis; Bronchopneumonia; Child; Encephalitis; Erythem | 1963 |
3 YEARS' EXPERIENCE WITH OXYPHENBUTAZONE IN THE TREATMENT OF RHEUMATIC DISORDERS.
Topics: Adolescent; Arthritis; Arthritis, Rheumatoid; Geriatrics; Gout; Osteoarthritis; Oxyphenbutazone; Pso | 1964 |
[CLINICAL TRIAL OF THE PYRAZOLE DERIVATIVE TANDERIL WITH RHEUMATIC AND OTHER DISEASES].
Topics: Adolescent; Aminosalicylic Acid; Aminosalicylic Acids; Arthritis; Arthritis, Rheumatoid; Biomedical | 1964 |
USE OF DRUGS IN THE TREATMENT OF RHEUMATOID ARTHRITIS.
Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Arthritis; Arthritis, Rheumatoid; Aspirin; Chl | 1964 |
NONSPECIFIC ANTI-INFLAMMATORY AGENTS. SOME NOTES ON THEIR PRACTICAL APPLICATION, ESPECIALLY IN RHEUMATIC DISORDERS.
Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents; Arthritis; Arthritis, Rheumatoid; Betamethasone; | 1964 |
TRIAL OF NIFENAZONE ("THYLIN").
Topics: Analgesics; Analgesics, Non-Narcotic; Antipyretics; Antipyrine; Arthritis; Arthritis, Rheumatoid; Ni | 1964 |
[2 CASES OF TANDERIL SIDE-EFFECTS IN CHILDREN].
Topics: Agranulocytosis; Arthritis; Arthritis, Rheumatoid; Blood Cell Count; Child; Humans; Leukopenia; Oxyp | 1964 |
[CONTRIBUTION TO THE STUDY OF INFLAMMATORY DISEASES OF THE LOCOMOTOR APPARATUS].
Topics: Antidepressive Agents; Arthritis; Arthritis, Rheumatoid; Drug Therapy; Fibromyalgia; Humans; Opipram | 1964 |
SPONDYLITIS.
Topics: Arthritis; Arthritis, Reactive; Arthritis, Rheumatoid; Diagnosis, Differential; Genetics, Medical; H | 1964 |
CORTICOSTEROID THERAPY IN RHEUMATOID ARTHRITIS. CRITERIA AND RESULTS.
Topics: Arthritis; Arthritis, Rheumatoid; Corticosterone; Dosage Forms; Drug Therapy; Fractures, Bone; Geria | 1964 |
NON-STEROID ANTIRHEUMATIC DRUGS.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Arthritis, Rheumatoid; Aspirin; Biomedical Resea | 1964 |
[INTERMITTENT HYDRARTHROSIS TREATED WITH OXYPHENBUTAZONE].
Topics: Arthritis, Rheumatoid; Drug Therapy; Hydrarthrosis; Oxyphenbutazone | 1964 |
Agranulocytosis and hepatitis as a result of Mexican drug therapy.
Topics: Adult; Agranulocytosis; Arthritis, Rheumatoid; Chemical and Drug Induced Liver Injury; Diazepam; Dru | 1984 |
Drug and non-drug factors influencing adverse reaction to pyrazoles.
Topics: Adult; Aged; Anemia; Arthritis, Rheumatoid; Dyspepsia; Female; Gastrointestinal Hemorrhage; Humans; | 1977 |
Psoriatic arthritis. Follow-up study.
Topics: Adult; Age Factors; Aged; Agglutination Tests; Arthritis; Arthritis, Rheumatoid; Female; Follow-Up S | 1976 |
[Effect of antirheumatic agents on DNA-systems and DNA repair of various cell systems].
Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; DNA; DNA Repair; Flufenamic Acid; Humans; In Vitro | 1976 |
Sensible prescribing. The treatment of rheumatoid arthritis.
Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Arthroplast | 1975 |
Inflammatory disease and its control in rheumatic disorders.
Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Female; Gout; Hum | 1975 |
[Clinical experience with tandearil-prednisolone].
Topics: Adult; Aged; Arthritis, Rheumatoid; Drug Evaluation; Drug Therapy, Combination; Female; Humans; Male | 1975 |
Adverse reactions with long-term use of phenylbutazone and oxyphenbutazone.
Topics: Adolescent; Adult; Aged; Arthritis, Rheumatoid; Child; Digestive System; Edema; Female; Fibromyalgia | 1969 |
Gout.
Topics: Allopurinol; Arthritis, Rheumatoid; Chondrocalcinosis; Colchicine; Diagnosis, Differential; Gout; Hu | 1973 |
Method of treatment of rheumatoid arthritis in different countries.
Topics: Adrenocorticotropic Hormone; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Chloroquine; | 1966 |
Hazards of drugs for rheumatoid arthritis.
Topics: 17-Hydroxycorticosteroids; Adrenocorticotropic Hormone; Analgesics; Arthritis, Rheumatoid; Aspirin; | 1967 |
Anti-inflammatory drugs in rheumatic diseases.
Topics: Adrenocorticotropic Hormone; Anti-Inflammatory Agents; Antimalarials; Arthritis, Rheumatoid; Aspirin | 1974 |
The effect of anti-inflammatory drugs on the protein-binding of 11-hydroxysteroids in human plasma in vitro.
Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Anti-Inflammatory Agents; Arthritis, Rheumatoi | 1969 |
The effects of anti-inflammatory drugs on the protein-binding of [1,2-3H] cortisol in human plasma in vitro.
Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Blood Proteins; Humans; Hydrocortisone; In | 1971 |
Treatment of rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Chronic Disease; Gold; Hot Temperature; Humans; Hydrocortisone; Indomethacin; | 1974 |
[Study of the efficacy and tolerance of oxyphenylbutazone-prednisone combination suppositories in rheumatology].
Topics: Arthritis, Rheumatoid; Drug Combinations; Drug Evaluation; Female; Humans; Male; Oxyphenbutazone; Pr | 1974 |
[In vivo investigation of the effect of antirheumatic drugs on DNA synthesis and DNA repair in patients with chronic rheumatoid arthritis (author's transl)].
Topics: Adult; Aged; Arthritis, Rheumatoid; Chronic Disease; Dimethylamines; DNA; DNA Repair; Female; Flufen | 1974 |
Analgesics and non-steroid anti-inflammatory agents in rheumatic disease.
Topics: Analgesics; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Bone Neoplasms; Gout; Humans; | 1972 |
[Which orthopedic indications are promising a successful therapy using Realin?].
Topics: Adolescent; Adult; Aged; Arthritis, Rheumatoid; Female; Humans; Male; Middle Aged; Oxyphenbutazone; | 1972 |
[Efficacy and compatibility of bumadizone-Ca in rheumatoid diseases. A comparison with oxyphenbutazone].
Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Brachial Plexus Neuritis; Dose-Response Relationshi | 1973 |
[Therapy of chronic polyarthritis. 2].
Topics: Adrenal Cortex Hormones; Arthritis, Rheumatoid; Aspirin; Betamethasone; Dexamethasone; Flufenamic Ac | 1972 |
[Pharmacology of butylmalonic acidmono-(1,2-diphenylhydrazide)-calcium (bumadizone-calcium)].
Topics: Analgesics; Animals; Anti-Inflammatory Agents; Arrhythmias, Cardiac; Arthritis, Rheumatoid; Blood Pr | 1973 |
[Evaluation of the oxyphenylbutazone prednisolone combination in patients with progressive chronic polyarthritis].
Topics: Adolescent; Adult; Aged; Arthritis, Rheumatoid; Capsules; Child; Drug Combinations; Evaluation Studi | 1974 |
[Clinical studies of a new antirheumatic-analgesic drug combination].
Topics: Adolescent; Adult; Aged; Analgesics; Aniline Compounds; Anti-Inflammatory Agents; Arthritis, Rheumat | 1972 |
Oxyphenbutazone and aplastic anemia.
Topics: Adult; Anemia, Aplastic; Arthritis, Rheumatoid; Humans; Male; Oxyphenbutazone | 1972 |
[Use of indomethacin in combination with other antirheumatic drugs in the therapy of chronic inflammatory rheumatism].
Topics: Arthritis, Rheumatoid; Aspirin; Chronic Disease; Dexamethasone; Drug Synergism; Flufenamic Acid; Gol | 1972 |
[Evaluation of a practical use of synthetic antimalarials in the treatment of rheumatoid polyarthritis].
Topics: Aged; Antimalarials; Arthritis, Rheumatoid; Aspirin; Chloroquine; Eye Diseases; Female; Follow-Up St | 1971 |
[The steroid-saving effect of indomethacin].
Topics: Arthritis, Rheumatoid; Chronic Disease; Drug Combinations; Drug Synergism; Glucocorticoids; Humans; | 1971 |
[Drug therapy of rheumatoid arthritis].
Topics: Arthritis, Rheumatoid; Aspirin; Chloroquine; Glucocorticoids; Humans; Oxyphenbutazone; Phenylbutazon | 1970 |
[Studies on the steroid-saving effect of oxyphenbutazone].
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Arthritis, Rheumatoid; Cortisone; Humans; Hydrocortisone | 1971 |
Folic-acid deficiency in rheumatoid arthritis: relation of levels of serum folic-acid activity to treatment with phenylbutazone.
Topics: Anemia, Macrocytic; Arthritis, Rheumatoid; Blood; Female; Folic Acid; Folic Acid Deficiency; Humans; | 1966 |
[Our 1st experiences with tanderil in the treatment of rheumatic diseases].
Topics: Adult; Aged; Arthritis, Rheumatoid; Female; Humans; Male; Middle Aged; Oxyphenbutazone; Rheumatic Fe | 1966 |
[Drug therapy of chronic polyarthritis].
Topics: Analgesics; Arthritis, Rheumatoid; Aspirin; Chloroquine; Disability Evaluation; Glucocorticoids; Gol | 1966 |
[Tanderil in the treatment of chronic evolutive polyarthritis].
Topics: Arthritis, Rheumatoid; Female; Humans; Oxyphenbutazone | 1966 |
[Clinical evaluation of oxyphenbutazone in chronic evolutive polyarthritis].
Topics: Arthritis, Rheumatoid; Female; Humans; Male; Oxyphenbutazone | 1966 |
[Study of renal function in patients with chronic inflammatory rheumatism under treatment with Tandearil].
Topics: Arthritis, Rheumatoid; Chronic Disease; Humans; Kidney; Kidney Function Tests; Oxyphenbutazone | 1966 |