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gamma-aminobutyric acid and Rheumatoid Arthritis

gamma-aminobutyric acid has been researched along with Rheumatoid Arthritis in 12 studies

gamma-Aminobutyric Acid: The most common inhibitory neurotransmitter in the central nervous system.
gamma-aminobutyric acid : A gamma-amino acid that is butanoic acid with the amino substituent located at C-4.

Research Excerpts

ExcerptRelevanceReference
"This study indicated that the Glutamine-Glutamate/GABA cycle played essential regulation roles in protective effect of THHE on rat RA following adjuvant-induced damage, and GLUD2 as an attractive target also provides great potential for development of therapy agents for rheumatoid arthritis and autoimmune diseases with less unfavorable tolerability profile."8.02Role of Glutamine-Glutamate/GABA cycle and potential target GLUD2 in alleviation of rheumatoid arthritis by Tripterygium hypoglaucum (levl.) Hutch based on metabolomics and molecular pharmacology. ( Guo, Y; Huang, S; Long, C; Qiao, X; Wang, Y; Yang, D; Yang, Y; Zhang, L; Zhang, X, 2021)
"This study indicated that the Glutamine-Glutamate/GABA cycle played essential regulation roles in protective effect of THHE on rat RA following adjuvant-induced damage, and GLUD2 as an attractive target also provides great potential for development of therapy agents for rheumatoid arthritis and autoimmune diseases with less unfavorable tolerability profile."4.02Role of Glutamine-Glutamate/GABA cycle and potential target GLUD2 in alleviation of rheumatoid arthritis by Tripterygium hypoglaucum (levl.) Hutch based on metabolomics and molecular pharmacology. ( Guo, Y; Huang, S; Long, C; Qiao, X; Wang, Y; Yang, D; Yang, Y; Zhang, L; Zhang, X, 2021)
"Current treatments for rheumatoid arthritis (RA) have long-term side effects such that new treatments are needed that can safely help manage the disease."1.37Oral GABA treatment downregulates inflammatory responses in a mouse model of rheumatoid arthritis. ( Dang, H; Kaufman, DL; Tian, J; Yong, J, 2011)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (25.00)29.6817
2010's6 (50.00)24.3611
2020's3 (25.00)2.80

Authors

AuthorsStudies
Won, W1
Choi, HJ1
Yoo, JY1
Kim, D1
Kim, TY1
Ju, Y1
Park, KD1
Lee, H1
Jung, SY1
Lee, CJ1
Shan, Y1
Zhao, J1
Zheng, Y1
Guo, S1
Schrodi, SJ1
He, D1
Peña, J1
Casas-Ferreira, AM1
Morales-Tenorio, M1
Moreno-Cordero, B1
Pérez-Pavón, JL1
Long, C1
Yang, Y2
Wang, Y1
Zhang, X1
Zhang, L1
Huang, S1
Yang, D1
Qiao, X1
Guo, Y1
Regan, DW1
Kashiwagi, D1
Dougan, B1
Sundsted, K1
Mauck, K1
Kurmann, PT1
Van Linthoudt, D1
So, AK1
Christianson, CA1
Corr, M1
Firestein, GS1
Mobargha, A1
Yaksh, TL1
Svensson, CI1
Tian, J1
Yong, J1
Dang, H1
Kaufman, DL1
Lantos, PM1
Jin, Z1
Mendu, SK1
Birnir, B1
Dani, K1
Ramachandran, R1
Capell, HA1
Madhok, R1
Kelley, JM1
Hughes, LB1
Bridges, SL1

Reviews

4 reviews available for gamma-aminobutyric acid and Rheumatoid Arthritis

ArticleYear
Understanding the function of the GABAergic system and its potential role in rheumatoid arthritis.
    Frontiers in immunology, 2023, Volume: 14

    Topics: Arthritis, Rheumatoid; GABA Plasma Membrane Transport Proteins; gamma-Aminobutyric Acid; Humans; Inf

2023
Update in perioperative medicine: practice changing evidence published in 2016.
    Hospital practice (1995), 2017, Volume: 45, Issue:4

    Topics: Amines; Analgesics; Anticoagulants; Antipsychotic Agents; Arthritis, Rheumatoid; Blood Transfusion;

2017
GABA is an effective immunomodulatory molecule.
    Amino acids, 2013, Volume: 45, Issue:1

    Topics: Animals; Arthritis, Rheumatoid; Diabetes Mellitus, Type 1; gamma-Aminobutyric Acid; Humans; Mice; Mu

2013
Does gamma-aminobutyric acid (GABA) influence the development of chronic inflammation in rheumatoid arthritis?
    Journal of neuroinflammation, 2008, Jan-03, Volume: 5

    Topics: Animals; Arthritis, Rheumatoid; gamma-Aminobutyric Acid; Humans; Interleukin-1; Interleukin-6; Matri

2008

Other Studies

8 other studies available for gamma-aminobutyric acid and Rheumatoid Arthritis

ArticleYear
Inhibiting peripheral and central MAO-B ameliorates joint inflammation and cognitive impairment in rheumatoid arthritis.
    Experimental & molecular medicine, 2022, Volume: 54, Issue:8

    Topics: Animals; Arthritis, Rheumatoid; Cells, Cultured; Cognitive Dysfunction; Fibroblasts; gamma-Aminobuty

2022
Determination of polyamines and related compounds in saliva via in situ derivatization and microextraction by packed sorbents coupled to GC-MS.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2019, Oct-15, Volume: 1129

    Topics: Arthritis, Rheumatoid; Biosensing Techniques; Female; gamma-Aminobutyric Acid; Gas Chromatography-Ma

2019
Role of Glutamine-Glutamate/GABA cycle and potential target GLUD2 in alleviation of rheumatoid arthritis by Tripterygium hypoglaucum (levl.) Hutch based on metabolomics and molecular pharmacology.
    Journal of ethnopharmacology, 2021, Dec-05, Volume: 281

    Topics: Animals; Arthritis, Rheumatoid; Female; gamma-Aminobutyric Acid; Gene Expression Regulation; Glutami

2021
Miller-Fisher syndrome in a patient with rheumatoid arthritis treated with adalimumab.
    Clinical rheumatology, 2009, Volume: 28, Issue:1

    Topics: Adalimumab; Aged; Amines; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antirheumatic A

2009
Characterization of the acute and persistent pain state present in K/BxN serum transfer arthritis.
    Pain, 2010, Volume: 151, Issue:2

    Topics: Activating Transcription Factor 3; Amines; Analgesics; Analysis of Variance; Animals; Arthritis, Rhe

2010
Oral GABA treatment downregulates inflammatory responses in a mouse model of rheumatoid arthritis.
    Autoimmunity, 2011, Volume: 44, Issue:6

    Topics: Animals; Arthritis, Experimental; Arthritis, Rheumatoid; Collagen; gamma-Aminobutyric Acid; Immunogl

2011
Chronic Lyme disease: the controversies and the science.
    Expert review of anti-infective therapy, 2011, Volume: 9, Issue:7

    Topics: Amines; Analgesics; Anti-Bacterial Agents; Arthritis, Rheumatoid; Borrelia burgdorferi; Chronic Dise

2011
Neuropathies in the rheumatoid patient: a case of the heavy hand.
    Scottish medical journal, 2005, Volume: 50, Issue:3

    Topics: Amines; Arthritis, Rheumatoid; Cyclohexanecarboxylic Acids; Electromyography; Female; Follow-Up Stud

2005