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mefenamic acid and Rheumatoid Arthritis

mefenamic acid has been researched along with Rheumatoid Arthritis in 40 studies

Mefenamic Acid: A non-steroidal anti-inflammatory agent with analgesic, anti-inflammatory, and antipyretic properties. It is an inhibitor of cyclooxygenase.
mefenamic acid : An aminobenzoic acid that is anthranilic acid in which one of the hydrogens attached to the nitrogen is replaced by a 2,3-dimethylphenyl group. Although classed as a non-steroidal anti-inflammatory drug, its anti-inflammatory properties are considered to be minor. It is used to relieve mild to moderate pain, including headaches, dental pain, osteoarthritis and rheumatoid arthritis.

Research Excerpts

ExcerptRelevanceReference
"A randomized double-blind within-patient study of mefenamic acid compared with ibuprofen was performed on forty patients with rheumatoid arthritis."9.04Mefenamic acid compared with ibuprofen in the treatment of rheumatoid arthritis. ( Leslie, RD, 1977)
"This paper reports a double-blind crossover trial comparing mefenamic acid (1500 mg/day) with ibuprofen (1200 mg/day) in the treatment of patients with rheumatoid arthritis receiving maintenance salicylate therapy."9.04Comparison of effectiveness of mefenamic acid and ibuprofen in treatment of rheumatoid arthritis. ( Muirden, KD; Stockman, A; Varigos, GA, 1976)
"A double-blind crossover study was carried out in 18 patients with classical rheumatoid arthritis to assess the effectiveness of mefenamic acid (500 mg t."5.04Mefenamic acid: an under-rated antirheumatic? ( Buchanan, WW; Hernandez, LA; MacLeod, M; Mavrikakis, ME; Rennie, JA, 1977)
"A randomized double-blind within-patient study of mefenamic acid compared with ibuprofen was performed on forty patients with rheumatoid arthritis."5.04Mefenamic acid compared with ibuprofen in the treatment of rheumatoid arthritis. ( Leslie, RD, 1977)
"This paper reports a double-blind crossover trial comparing mefenamic acid (1500 mg/day) with ibuprofen (1200 mg/day) in the treatment of patients with rheumatoid arthritis receiving maintenance salicylate therapy."5.04Comparison of effectiveness of mefenamic acid and ibuprofen in treatment of rheumatoid arthritis. ( Muirden, KD; Stockman, A; Varigos, GA, 1976)
"Three patients developed autoimmune haemolytic anaemia while being treated with mefenamic acid."1.25Autoimmune haemolytic anaemia and mefenamic acid therapy. ( Bacon, PA; Myles, AB; Scott, GL, 1968)

Research

Studies (40)

TimeframeStudies, this research(%)All Research%
pre-199038 (95.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (5.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chen, YR1
Hsieh, FI1
Chang, CC1
Chi, NF1
Wu, HC1
Chiou, HY1
Patel, P1
Madan, P1
Lin, S1
CAHILL, WJ1
HILL, RD1
JESSOP, J1
KENDALL, PH1
Mason, RM1
Barnardo, DE1
Fox, WR1
Weatherall, M2
Simon, LS1
Mills, JA1
Lee, P2
Anderson, JA2
Miller, J2
Webb, J2
Buchanan, WW6
Huskisson, EC1
Leynadier, F1
Perrault, M1
Mavrikakis, ME2
Madkour, MM1
MacLeod, M1
Hernandez, LA1
Rennie, JA1
Leslie, RD1
Reinicke, C1
Stephens, WH1
El-Ghobarey, AF1
Macleod, MM1
Trinus, FP1
Mokhort, NA1
Farquet, JJ1
Dayer, JM1
Miescher, PA1
Dormidontov, EN1
Korshunov, NI1
Baranova, EIa1
Stockman, A1
Varigos, GA1
Muirden, KD1
Wax, J1
Tessman, DK1
Winder, CV1
Stephens, MD1
Juby, LD1
Axon, AT1
Wright, V1
Winstanley, P1
Rothwell, J1
Myles, AB2
Bacon, PA2
Williams, KA1
Cosh, JA1
Martel, RR1
Klicius, J1
Herr, F1
Wawrzyńska-Pagowska, J1
Jeremy, R1
Cardoe, N1
Dick, WC1
Porro, A1
Schmied, P1
Van Rossum, P1
Fallet, GH1
Rau, R1
Camus, JP1
Jackson, JM1
Quinlan, J1
Goatcher, P1
Böni, A1
Lockie, LM1
Kater, RM1
Scott, GL1

Reviews

8 reviews available for mefenamic acid and Rheumatoid Arthritis

ArticleYear
Nonsteroidal antiinflammatory drugs (second of two parts).
    The New England journal of medicine, 1980, May-29, Volume: 302, Issue:22

    Topics: Anti-Inflammatory Agents; Arthritis; Arthritis, Rheumatoid; Fenoprofen; Humans; Ibuprofen; Mefenamic

1980
Antiinflammatory drugs.
    Seminars in arthritis and rheumatism, 1977, Volume: 7, Issue:1

    Topics: Adult; Anti-Inflammatory Agents; Apazone; Arthritis, Rheumatoid; Aspirin; Benzylidene Compounds; Chi

1977
[Nonsteroid antirheumatic agents].
    Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1977, Jul-15, Volume: 32, Issue:14

    Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Fenoprofen; Flufenamic Acid; Humans; Indomethacin;

1977
[Pharmacological and clinical aspects of mefenamic acid--nonsteroid anti-inflammatory drug (review of the literature)].
    Vrachebnoe delo, 1979, Issue:3

    Topics: Animals; Arthritis, Rheumatoid; Humans; Hypersensitivity; Mefenamic Acid; Myocarditis; Rheumatic Dis

1979
[Clinical use of non-steroid anti-inflammatory agents].
    Reumatologia, 1974, Volume: 12, Issue:1

    Topics: Animals; Anti-Inflammatory Agents; Antigen-Antibody Complex; Arthritis, Rheumatoid; Aspirin; Cell Mi

1974
A critical appraisal of therapy in rheumatoid arthritis.
    The Medical journal of Australia, 1968, May-11, Volume: 1, Issue:19

    Topics: Anti-Inflammatory Agents; Antimalarials; Antimetabolites; Arthritis, Rheumatoid; Aspirin; Flufenamic

1968
Advances in the treatment of rheumatic disorders.
    The Practitioner, 1971, Volume: 207, Issue:240

    Topics: Acetaminophen; Analgesics; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Chloroquine; Female; Flu

1971
[The conservative treatment of chronic inflammatory rheumatism].
    Schweizerische medizinische Wochenschrift, 1969, Jun-28, Volume: 99, Issue:26

    Topics: Adolescent; Adrenal Cortex Hormones; Adult; Analgesics; Anti-Inflammatory Agents; Antimalarials; Art

1969

Trials

12 trials available for mefenamic acid and Rheumatoid Arthritis

ArticleYear
Evaluation of analgesic action and efficacy of antirheumatic drugs. Study of 10 drugs in 684 patients with rheumatoid arthritis.
    The Journal of rheumatology, 1976, Volume: 3, Issue:3

    Topics: Acetaminophen; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Aspirin; Clinical Tri

1976
Mefenamic acid: an under-rated antirheumatic?
    Current medical research and opinion, 1977, Volume: 4, Issue:8

    Topics: Adult; Arthritis, Rheumatoid; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Indomet

1977
Mefenamic acid compared with ibuprofen in the treatment of rheumatoid arthritis.
    The Journal of international medical research, 1977, Volume: 5, Issue:3

    Topics: Arthritis, Rheumatoid; Clinical Trials as Topic; Dose-Response Relationship, Drug; Female; Humans; I

1977
A double-blind, crossover trial of mefenamic acid, sulindac and flurbiprofen in rheumatoid arthritis.
    Current medical research and opinion, 1979, Volume: 5, Issue:10

    Topics: Adult; Aged; Arthritis, Rheumatoid; Clinical Trials as Topic; Double-Blind Method; Female; Flurbipro

1979
Comparison of effectiveness of mefenamic acid and ibuprofen in treatment of rheumatoid arthritis.
    The Medical journal of Australia, 1976, Nov-27, Volume: 2, Issue:22

    Topics: Arthritis, Rheumatoid; Clinical Trials as Topic; Female; Humans; Ibuprofen; Male; Mefenamic Acid; Ph

1976
[Comparative evaluation of the therapeutic efficiency of flurbiprofene in rheumatoid polyarthritis].
    Revue du rhumatisme et des maladies osteo-articulaires, 1975, Volume: 42, Issue:6

    Topics: Acetaminophen; Arthritis, Rheumatoid; Aspirin; Biphenyl Compounds; Chemical Phenomena; Chemistry; Cl

1975
Mefenamic acid in rheumatoid arthritis.
    Annals of the rheumatic diseases, 1967, Volume: 26, Issue:6

    Topics: Adrenocorticotropic Hormone; Adult; Aged; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin;

1967
Clinical trials of the fenamates. The value of computers in analysing clinical trials.
    Annals of physical medicine, 1966, Volume: Suppl

    Topics: Analysis of Variance; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Clinical Trials as Topic; Com

1966
A clinical trial of flufenamic acid in the treatment of rheumatoid arthritis.
    Annals of physical medicine, 1966, Volume: Suppl

    Topics: Abdomen, Acute; Acetaminophen; Aluminum; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspartate

1966
[Antipyretic activity of mefenamic acid. Double-blind clinical studies in comparison with amidopyrine and a placebo].
    Minerva medica, 1971, Oct-20, Volume: 62, Issue:79

    Topics: Adolescent; Aminopyrine; Analgesics; Arthritis, Rheumatoid; Clinical Trials as Topic; Drug Tolerance

1971
Mefenamic acid.
    British medical journal, 1966, Dec-17, Volume: 2, Issue:5528

    Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Clinical Trials as Topic; Female; Humans; Mefenamic

1966
Double-blind evaluation of the analgesic and toxic effects of flufenamic acid and mefenamic acid in patients with chronic pain.
    The Medical journal of Australia, 1968, May-18, Volume: 1, Issue:20

    Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Flufenamic Acid; Fluorine; Humans; Mefenamic Acid;

1968

Other Studies

20 other studies available for mefenamic acid and Rheumatoid Arthritis

ArticleYear
Effect on Risk of Stroke and Acute Myocardial Infarction of Nonselective Nonsteroidal Anti-Inflammatory Drugs in Patients With Rheumatoid Arthritis.
    The American journal of cardiology, 2018, 05-15, Volume: 121, Issue:10

    Topics: Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Celecoxib;

2018
Formulation and evaluation of time-controlled triple-concentric mefenamic acid tablets for rheumatoid arthritis.
    Pharmaceutical development and technology, 2014, Volume: 19, Issue:3

    Topics: Acrylic Resins; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Delayed-Action Prepa

2014
TRIAL OF MEFENAMIC ACID.
    Annals of physical medicine, 1965, Volume: 8

    Topics: Analgesics; Analgesics, Non-Narcotic; Antipyretics; Arthritis; Arthritis, Rheumatoid; Bone Neoplasms

1965
Discussion on the pharmacology of the fenamates.
    Annals of physical medicine, 1966, Volume: Suppl

    Topics: Abnormalities, Drug-Induced; Analgesia; Animals; Anti-Inflammatory Agents; Arthritis, Rheumatoid; As

1966
Assessment of drugs in out-patients with rheumatoid arthritis. Evaluation of methods and a comparison of mefenamic and flufenamic acids with phenylbutazone and aspirin.
    Annals of the rheumatic diseases, 1967, Volume: 26, Issue:5

    Topics: Acetaminophen; Adult; Agglutination Tests; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin;

1967
[Anti-inflammatory agents in current therapeutics].
    La Revue du praticien, 1975, Jan-21, Volume: 25, Issue:5

    Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Anti-Inflammatory Agents; Arthritis, Rheumatoi

1975
The place of mefenamic acid in the treatment of rheumatoid arthritis.
    Scottish medical journal, 1978, Volume: 23, Issue:2

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Flufenamic Acid; Humans; Mefenamic A

1978
[Autoimmune hemolytic anemia induced by mefenamic acid].
    Schweizerische medizinische Wochenschrift, 1978, Sep-30, Volume: 108, Issue:39

    Topics: Anemia, Hemolytic, Autoimmune; Antibodies; Arthritis, Rheumatoid; Erythrocytes; Humans; Immunoglobul

1978
[Antirheumatic non-steroid drugs in the treatment of rheumatoid arthritis].
    Terapevticheskii arkhiv, 1978, Volume: 50, Issue:9

    Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Drug Evaluation; Humans; Ibuprofen; Indome

1978
A sensitive method for the comparative bioassay of nonsteroidal anti-inflammatory compounds in adjuvant-induced primary inflammation in the rat.
    The Journal of pharmacology and experimental therapeutics, 1975, Volume: 192, Issue:1

    Topics: Aminopyrine; Analysis of Variance; Animals; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin

1975
Intestinal permeability and inflammation in rheumatoid arthritis.
    British journal of rheumatology, 1986, Volume: 25, Issue:2

    Topics: Arthritis, Rheumatoid; Humans; Intestine, Small; Mefenamic Acid; Permeability

1986
Anti-inflammatory drugs in rheumatic diseases.
    The Practitioner, 1974, Volume: 213, Issue:1276 SPEC

    Topics: Adrenocorticotropic Hormone; Anti-Inflammatory Agents; Antimalarials; Arthritis, Rheumatoid; Aspirin

1974
Determination of the therapeutic mean effective doses of several anti-inflammatory agents in adjuvant arthritic rats.
    Canadian journal of physiology and pharmacology, 1974, Volume: 52, Issue:4

    Topics: Aminopyrine; Animals; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Dose-Response Relati

1974
[Drug therapy of progressive chronic polyarthritis].
    Therapeutische Umschau. Revue therapeutique, 1972, Volume: 29, Issue:8

    Topics: Alkylating Agents; Analgesics; Anti-Bacterial Agents; Anti-Inflammatory Agents; Antimalarials; Antim

1972
[The new anti-inflammatory acids. Niflumic acid in rheumatology].
    La Presse medicale, 1968, May-04, Volume: 76, Issue:22

    Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Flufenamic Acid; Fluorine; Humans; Mefenamic Acid;

1968
Discussion on clinical trials of the fenamates.
    Annals of physical medicine, 1966, Volume: Suppl

    Topics: Analgesia; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspirin; Central Nervous System; Flufena

1966
Mefanamic acid-induced haemolytic anaemia.
    British medical journal, 1970, May-02, Volume: 2, Issue:5704

    Topics: Adult; Anemia, Hemolytic, Autoimmune; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Humans; Male;

1970
[Therapy of progressive chronic polyarthritis].
    Deutsche medizinische Wochenschrift (1946), 1970, Apr-10, Volume: 95, Issue:15

    Topics: Arthritis, Rheumatoid; Chronic Disease; Cortisone; Flufenamic Acid; Gold; Humans; Indoles; Mefenamic

1970
Current evaluation of drugs for treating arthritis.
    Postgraduate medicine, 1971, Volume: 49, Issue:4

    Topics: Acetaminophen; Adrenal Cortex Hormones; Arthritis; Arthritis, Rheumatoid; Aspirin; Chloroquine; Code

1971
Autoimmune haemolytic anaemia and mefenamic acid therapy.
    British medical journal, 1968, Aug-31, Volume: 3, Issue:5617

    Topics: Anemia, Hemolytic, Autoimmune; Anti-Inflammatory Agents; Antibody Formation; Arthritis, Rheumatoid;

1968