deferoxamine has been researched along with Rheumatoid Arthritis in 19 studies
Deferoxamine: Natural product isolated from Streptomyces pilosus. It forms iron complexes and is used as a chelating agent, particularly in the mesylate form.
desferrioxamine B : An acyclic desferrioxamine that is butanedioic acid in which one of the carboxy groups undergoes formal condensation with the primary amino group of N-(5-aminopentyl)-N-hydroxyacetamide and the second carboxy group undergoes formal condensation with the hydroxyamino group of N(1)-(5-aminopentyl)-N(1)-hydroxy-N(4)-[5-(hydroxyamino)pentyl]butanediamide. It is a siderophore native to Streptomyces pilosus biosynthesised by the DesABCD enzyme cluster as a high affinity Fe(III) chelator.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Eleven patients with rheumatoid arthritis (RA) were treated with intraarticular deferoxamine or placebo to test the hypothesis that iron chelation decreased hydroxyl radical mediated lipid peroxidation in RA." | 9.06 | Deferoxamine induced decreases of lipid peroxides in rheumatoid arthritis. ( Fox, IH; Fudman, EJ; Till, GO, 1987) |
| "Eleven patients with rheumatoid arthritis (RA) were treated with intraarticular deferoxamine or placebo to test the hypothesis that iron chelation decreased hydroxyl radical mediated lipid peroxidation in RA." | 5.06 | Deferoxamine induced decreases of lipid peroxides in rheumatoid arthritis. ( Fox, IH; Fudman, EJ; Till, GO, 1987) |
| " In the present study, we evaluated RAc1 nano particle effects on hyperalgesia and liver hepcidin and serum IL-1β and TNF-α expression levels during acute and chronic phases of adjuvant-induced inflammation in male rats and compared its effects with Deferoxamine." | 3.91 | Anti-hyperalgesia effect of nanchelating based nano particle, RAc1, can be mediated via liver hepcidin expression modulation during persistent inflammation. ( Houshmandi, E; Kalanaky, S; Manaheji, H; Mirjafai, S; Mohammadi, M; Nazemian, V; Zaringhalam, J, 2019) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (57.89) | 18.7374 |
| 1990's | 4 (21.05) | 18.2507 |
| 2000's | 2 (10.53) | 29.6817 |
| 2010's | 2 (10.53) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Nazemian, V | 1 |
| Kalanaky, S | 1 |
| Manaheji, H | 1 |
| Houshmandi, E | 1 |
| Mohammadi, M | 1 |
| Zaringhalam, J | 1 |
| Mirjafai, S | 1 |
| Akiyama, M | 1 |
| Kaneko, Y | 1 |
| Hanaoka, H | 1 |
| Kuwana, M | 1 |
| Takeuchi, T | 1 |
| Kinderlerer, AR | 1 |
| Steinberg, R | 1 |
| Johns, M | 1 |
| Harten, SK | 1 |
| Lidington, EA | 1 |
| Haskard, DO | 1 |
| Maxwell, PH | 1 |
| Mason, JC | 1 |
| Lawson, AA | 1 |
| Owen, ET | 1 |
| Mowat, AG | 1 |
| Giordano, N | 2 |
| Fioravanti, A | 1 |
| Sancasciani, S | 1 |
| Marcolongo, R | 2 |
| Borghi, C | 1 |
| Maddali Bongi, S | 1 |
| Palermo, C | 1 |
| Bianucci, G | 1 |
| Salvarani, C | 1 |
| Baricchi, R | 1 |
| Lasagni, D | 1 |
| Boiardi, L | 1 |
| Piccinini, R | 1 |
| Brunati, C | 1 |
| Macchioni, P | 1 |
| Portioli, I | 1 |
| Hisakawa, N | 1 |
| Nishiya, K | 1 |
| Tahara, K | 1 |
| Matsumori, A | 1 |
| Hashimoto, K | 1 |
| Beren, J | 1 |
| Hill, SL | 1 |
| Diener-West, M | 1 |
| Rose, NR | 1 |
| Sorokina, LP | 1 |
| Di Lollo, F | 1 |
| Morini, PL | 1 |
| Fazzini, G | 1 |
| Niosi, L | 1 |
| Parkes, HG | 1 |
| Allen, RE | 1 |
| Furst, A | 1 |
| Blake, DR | 1 |
| Grootveld, MC | 1 |
| Magarò, M | 1 |
| Zoli, A | 1 |
| Altomonte, L | 1 |
| Mirone, L | 1 |
| Corvino, G | 1 |
| Storti, S | 1 |
| Marra, R | 1 |
| Ricerca, BM | 1 |
| Pagano, L | 1 |
| Di Cesare, L | 1 |
| Halliwell, B | 1 |
| Gutteridge, JM | 1 |
| Blake, D | 1 |
| Fudman, EJ | 1 |
| Till, GO | 1 |
| Fox, IH | 1 |
| Calabria, AA | 1 |
| Lalumera, M | 1 |
| Mazzullo, G | 1 |
| Cavallo, G | 1 |
| Morozzi, G | 1 |
| Polson, RJ | 2 |
| Jawad, AS | 1 |
| Bomford, A | 2 |
| Berry, H | 2 |
| Williams, R | 2 |
| Jawed, A | 1 |
| Karlsson, B | 1 |
| Lagercrantz, R | 1 |
| Brann, I | 1 |
| Strandberg, O | 1 |
| Reizenstein, P | 1 |
1 review available for deferoxamine and Rheumatoid Arthritis
| Article | Year |
|---|---|
Acute kidney injury due to renal sarcoidosis during etanercept therapy: a case report and literature review.
Topics: Acute Kidney Injury; Aged, 80 and over; Antirheumatic Agents; Arthritis, Rheumatoid; Deferoxamine; D | 2015 |
1 trial available for deferoxamine and Rheumatoid Arthritis
| Article | Year |
|---|---|
Deferoxamine induced decreases of lipid peroxides in rheumatoid arthritis.
Topics: Adult; Arthritis, Rheumatoid; Deferoxamine; Double-Blind Method; Female; Ferritins; Humans; Hydroxid | 1987 |
17 other studies available for deferoxamine and Rheumatoid Arthritis
| Article | Year |
|---|---|
Anti-hyperalgesia effect of nanchelating based nano particle, RAc1, can be mediated via liver hepcidin expression modulation during persistent inflammation.
Topics: Animals; Arthritis, Experimental; Arthritis, Rheumatoid; Deferoxamine; Hepcidins; Humans; Hyperalges | 2019 |
Statin-induced expression of CD59 on vascular endothelium in hypoxia: a potential mechanism for the anti-inflammatory actions of statins in rheumatoid arthritis.
Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Atorvastatin; CD55 Antigens; CD59 Antigens; Cells, | 2006 |
Nature of anaemia in rheumatoid arthritis. VII. Storage of iron in rheumatoid disease.
Topics: Adult; Anemia; Arthritis, Rheumatoid; Deferoxamine; Female; Hemoglobinometry; Humans; Iron; Male; Mi | 1967 |
Increased storage of iron and anaemia in rheumatoid arthritis: usefulness of desferrioxamine.
Topics: Adult; Aged; Anemia; Arthritis, Rheumatoid; Deferoxamine; Female; Ferritins; Humans; Iron; Male; Mid | 1984 |
[Sideropenic anemia in rheumatoid arthritis: diagnostic usefulness of serum ferritin, unsaturated transferrin and induced urinary siderosis].
Topics: Anemia, Hypochromic; Arthritis, Rheumatoid; Deferoxamine; Ferritins; Humans; Iron; Transferrin | 1983 |
Effects of desferrioxamine therapy on chronic disease anemia associated with rheumatoid arthritis.
Topics: Anemia; Arthritis, Rheumatoid; Chronic Disease; Deferoxamine; Dose-Response Relationship, Drug; Enzy | 1996 |
Down regulation by iron of prostaglandin E2 production by human synovial fibroblasts.
Topics: Aged; Arthritis, Rheumatoid; Cells, Cultured; Citric Acid; Deferoxamine; Depression, Chemical; Dinop | 1998 |
Effect of pre-loading oral glucosamine HCl/chondroitin sulfate/manganese ascorbate combination on experimental arthritis in rats.
Topics: Animals; Arthritis, Rheumatoid; Ascorbic Acid; Autoantibodies; Chondroitin Sulfates; Collagen; Defer | 2001 |
[Despheral test in diagnosis of iron stores in patients with rheumatoid polyarthritis].
Topics: Arthritis, Rheumatoid; Deferoxamine; Humans; Iron | 1975 |
[Desferrioxamine in the diagnosis of hypo-, normo-, and hypersiderotic hyposideremia].
Topics: Adult; Aged; Anemia, Hypochromic; Arthritis, Rheumatoid; Breast Neoplasms; Deferoxamine; Duodenal Ul | 1977 |
Speciation of non-transferrin-bound iron ions in synovial fluid from patients with rheumatoid arthritis by proton nuclear magnetic resonance spectroscopy.
Topics: Arthritis, Rheumatoid; Deferoxamine; Ferritins; Humans; Iron; Magnetic Resonance Spectroscopy; Synov | 1991 |
Iron chelation in rheumatoid arthritis: clinical and laboratory evaluation.
Topics: Adult; Arthritis, Rheumatoid; beta 2-Microglobulin; Deferoxamine; Drug Evaluation; Female; Ferritins | 1990 |
Metal ions and oxygen radical reactions in human inflammatory joint disease.
Topics: Arthritis, Rheumatoid; Bleomycin; Blood Bactericidal Activity; Deferoxamine; Ferritins; Free Radical | 1985 |
[In vitro study on the possible inflammatory mechanism of ferrous ions: effect on the production of oxygen free radicals].
Topics: Arthritis, Rheumatoid; Deferoxamine; Ferric Compounds; Ferrous Compounds; Humans; Hydroxides; Hydrox | 1985 |
Treatment of rheumatoid arthritis with desferrioxamine.
Topics: Adult; Aged; Arthritis, Rheumatoid; Deferoxamine; Drug Evaluation; Female; Humans; Infusions, Parent | 1986 |
Treatment of rheumatoid arthritis with desferrioxamine: relation between stores of iron before treatment and side effects.
Topics: Adult; Aged; Arthritis, Rheumatoid; Deferoxamine; Female; Humans; Iron; Male; Middle Aged | 1985 |
[The use of desferrioxamine in iron poisoning and hemosiderosis].
Topics: Arthritis, Rheumatoid; Child, Preschool; Deferoxamine; Hematopoietic System; Hemosiderosis; Humans; | 1965 |