Page last updated: 2024-12-08

acetyl 4-aminosalicylic acid

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Cross-References

ID SourceID
PubMed CID147034
SCHEMBL ID4737527
MeSH IDM0229971

Synonyms (15)

Synonym
brn 3285180
acetyl p-aminosalicylic acid
acetyl-pas-saeure [german]
salicylic acid, 4-amino-, acetate
acetyl 4-aminosalicylic acid
2-acetyloxy-4-aminobenzoic acid
102338-89-6
4-14-00-01972 (beilstein handbook reference)
acetyl-pas-saeure
2-acetoxy4-aminobenzoic acid
OGBZOXBEULJKHF-UHFFFAOYSA-N
SCHEMBL4737527
DTXSID80144916
acetyl-p-aminosalicylic acid
2-acetoxy-4-aminobenzoic acid

Research Excerpts

Pharmacokinetics

ExcerptReferenceRelevance
"(a) Single-dose pharmacokinetic study in healthy volunteers; (b) Day-1 and day-8 pharmacokinetic comparison in patients with multidrug-resistant tuberculosis (MDR-TB)."( Pharmacokinetic evaluation of para-aminosalicylic acid granules.
Berning, SE; Henshaw, TL; Huitt, GA; James, GT; Nitta, AT; Peloquin, CA,
)
0.13

Bioavailability

ExcerptReferenceRelevance
"To determine the bioavailability and renal elimination of para-aminosalicylic acid (PAS) and its inactive metabolite acetyl-para-aminosalicylic acid (AcPAS) from a new PAS formulation."( Pharmacokinetic evaluation of para-aminosalicylic acid granules.
Berning, SE; Henshaw, TL; Huitt, GA; James, GT; Nitta, AT; Peloquin, CA,
)
0.13

Dosage Studied

ExcerptRelevanceReference
" This study was designed to investigate the pharmacokinetics of PAS and its distribution in brain to help better design the dosing regimen for clinical trials."( Brain regional pharmacokinetics of p-aminosalicylic acid and its N-acetylated metabolite: effectiveness in chelating brain manganese.
Hong, L; Jiang, W; Jiang, Y; Pan, H; Zeng, S; Zheng, W, 2011
)
0.37
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (15)

TimeframeStudies, This Drug (%)All Drugs %
pre-19901 (6.67)18.7374
1990's1 (6.67)18.2507
2000's0 (0.00)29.6817
2010's4 (26.67)24.3611
2020's9 (60.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 12.03

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index12.03 (24.57)
Research Supply Index2.94 (2.92)
Research Growth Index4.97 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (12.03)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials1 (5.88%)5.53%
Reviews1 (5.88%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other15 (88.24%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]