acetylcysteine has been researched along with Rheumatoid Arthritis in 27 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (18.52) | 18.7374 |
| 1990's | 4 (14.81) | 18.2507 |
| 2000's | 5 (18.52) | 29.6817 |
| 2010's | 8 (29.63) | 24.3611 |
| 2020's | 5 (18.52) | 2.80 |
| Authors | Studies |
|---|---|
| Ahmadzadeh, A; Jamali, F; Sahraei, Z; Salamzadeh, J | 1 |
| Esalatmanesh, K; Esalatmanesh, R; Jamali, A; Khabbazi, A; Malek Mahdavi, A; Soleimani, Z | 1 |
| Mikuteit, M; Tsikas, D | 1 |
| Chan, JTW; Chen, C; Chen, R; Chung, SK; Huang, B; Law, BYK; Li, Z; Luo, W; Mok, SWF; Ng, JPL; Qu, L; Qu, Y; Su, L; Wang, L; Wang, X; Wang, Y; Wong, VKW; Xu, X; Yang, J; Yang, L; Yun, X; Zeng, Y; Zhang, W | 1 |
| Endo, N; Kanai, T; Kawashima, H; Kijima, Y; Kondo, N; Ogose, A; Okada, M; Okumura, G; Sano, H | 1 |
| Ataei, S; Basiri, Z; Batooei, M; Eshraghi, A; Mehrpooya, M; Shahdoust, M; Tahamoli-Roudsari, A; Yasrebifar, F | 1 |
| Ataei, S; Basiri, Z; Hashemi, G; Kheiripour, N; Mehrpooya, M; Mirjalili, M; Ranjbar, A; Shahdoust, M; Tahamoli-Roudsari, A | 1 |
| Guo, L; Jin, J; Li, J; Sheng, X; Wu, M; Xia, Y; Xu, T; Zhang, C; Zhao, L | 1 |
| Chen, H; Liao, QM; Pan, J; Wang, JD; Xia, XR | 1 |
| Huang, M; Liang, L; Qiu, Q; Shi, M; Xiao, Y; Xu, H; Yang, X; Zeng, S; Zou, Y | 1 |
| Shang, CH; Zhang, QQ; Zhou, JH | 1 |
| Huang, M; Liang, L; Qiu, Q; Shi, M; Xiao, Y; Xu, H; Yang, X; Zeng, S; Zhan, Z; Zou, Y | 1 |
| Kim, BM; Kim, HR; Kim, KW; Lee, KA; Lee, SH | 1 |
| Boehncke, WH; Elliott, PJ; Zollner, TM | 1 |
| Barnes, S; Grizzle, WE; Kimberly, RP; Koopman, WJ; Liu, C; Mountz, JD; Wang, J; Yang, X; Yu, S; Zhang, HG; Zhang, S | 1 |
| Deutsch, M; Herman, S; Zurgil, N | 1 |
| Arsenault, L; Banquerigo, ML; Boyle, DL; Brahn, E; Cheng, TP; Cruz, TF; Firestein, GS; Oliver, SJ | 1 |
| Fischbein, L; Taylor, PW | 1 |
| Ida, N; Maeda, K; Miyazaki, T; Murata, Y; Nagaya, T; Sato, M; Seo, H | 1 |
| Kato, T; Okamoto, T; Sakurada, S | 1 |
| Blake, DR; Grootveld, M; Lynch, EJ; Patel, IY; Silwood, CJ | 1 |
| Koch, AE; Morel, JC; Park, CC; Woods, JM | 1 |
| Swaak, AJ; Vreugdenhil, G | 1 |
| Christophidis, N; Drummer, OH; Horowitz, JD; Louis, WJ | 1 |
| Csuka, ME; Hansen, RM; McCarty, DJ; Saryan, LA | 1 |
| Leibowitz, HM; Messner, K | 1 |
| Absolon, MJ; Brown, CA | 1 |
2 review(s) available for acetylcysteine and Rheumatoid Arthritis
| Article | Year |
|---|---|
N-Acetyl-L-cysteine in human rheumatoid arthritis and its effects on nitric oxide (NO) and malondialdehyde (MDA): analytical and clinical considerations.
Topics: Acetylcysteine; Arthritis, Rheumatoid; Biomarkers; Humans; Malondialdehyde; Nitric Oxide; Oxidative Stress | 2022 |
Proteasome inhibition: a new anti-inflammatory strategy.
Topics: Acetylcysteine; Animals; Anti-Inflammatory Agents; Antineoplastic Agents; Arthritis, Rheumatoid; Asthma; Boronic Acids; Bortezomib; Clinical Trials as Topic; Cysteine Endopeptidases; Disease Models, Animal; Humans; Inflammation; Lysine; Models, Biological; Models, Chemical; Multienzyme Complexes; Multiple Sclerosis; Neoplasms; NF-kappa B; Peptides; Protease Inhibitors; Proteasome Endopeptidase Complex; Psoriasis; Pyrazines; Reperfusion Injury | 2003 |
4 trial(s) available for acetylcysteine and Rheumatoid Arthritis
| Article | Year |
|---|---|
Study of the Effects of N-acetylcysteine on Inflammatory Biomarkers and Disease Activity Score in Patients with Rheumatoid Arthritis.
Topics: Acetylcysteine; Administration, Oral; Arthritis, Rheumatoid; Biomarkers; Blood Sedimentation; C-Reactive Protein; Cytokines; Disease Management; Disease Susceptibility; Humans; Inflammation Mediators; Severity of Illness Index; Treatment Outcome | 2021 |
Effects of N-acetylcysteine supplementation on disease activity, oxidative stress, and inflammatory and metabolic parameters in rheumatoid arthritis patients: a randomized double-blind placebo-controlled trial.
Topics: Acetylcysteine; Antioxidants; Arthritis, Rheumatoid; Biomarkers; C-Reactive Protein; Dietary Supplements; Double-Blind Method; Humans; Oxidative Stress | 2022 |
Evaluating the Effect of Oral N-acetylcysteine as an Adjuvant Treatment on Clinical Outcomes of Patients with Rheumatoid Arthritis: A Randomized, Double Blind Clinical Trial.
Topics: Acetylcysteine; Administration, Oral; Adult; Aged; Antirheumatic Agents; Arthritis, Rheumatoid; Double-Blind Method; Drug Therapy, Combination; Female; Free Radical Scavengers; Humans; Male; Middle Aged; Treatment Outcome | 2018 |
A Pilot Study to Evaluate the Effects of Oral N-Acetyl Cysteine on Inflammatory and Oxidative Stress Biomarkers in Rheumatoid Arthritis.
Topics: Acetylcysteine; Administration, Oral; Adult; Aged; Anti-Inflammatory Agents; Antioxidants; Antirheumatic Agents; Arthritis, Rheumatoid; Biomarkers; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Inflammation; Male; Middle Aged; Oxidative Stress; Pilot Projects | 2019 |
21 other study(ies) available for acetylcysteine and Rheumatoid Arthritis
| Article | Year |
|---|---|
Topics: Acetylcysteine; Aldehydes; Animals; Arthritis, Rheumatoid; Humans; Leukocytes, Mononuclear; Rats | 2023 |
The JNK pathway represents a novel target in the treatment of rheumatoid arthritis through the suppression of MMP-3.
Topics: Acetylcysteine; Adult; Aged, 80 and over; Antioxidants; Arthritis, Rheumatoid; Cell Survival; Cells, Cultured; Drug Delivery Systems; Female; Humans; MAP Kinase Signaling System; Matrix Metalloproteinase 3; Middle Aged; Synoviocytes; Treatment Outcome | 2020 |
α-Mangostin promotes apoptosis of human rheumatoid arthritis fibroblast-like synoviocytes by reactive oxygen species-dependent activation of ERK1/2 mitogen-activated protein kinase.
Topics: Acetylcysteine; Aged; Apoptosis; Arthritis, Rheumatoid; Benzamides; Caspase 3; Caspase 9; Cell Survival; Cytochromes c; Female; Humans; MAP Kinase Signaling System; Membrane Potential, Mitochondrial; Middle Aged; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Protein Kinase Inhibitors; Reactive Oxygen Species; Sulfonamides; Synoviocytes; Xanthones | 2019 |
Suberoylanilide Hydroxamic Acid, an Inhibitor of Histone Deacetylase, Induces Apoptosis in Rheumatoid Arthritis Fibroblast-Like Synoviocytes.
Topics: Acetylcysteine; Apoptosis; Arthritis, Rheumatoid; bcl-X Protein; Caspase 3; Cell Survival; Cells, Cultured; Fibroblasts; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Myeloid Cell Leukemia Sequence 1 Protein; NF-KappaB Inhibitor alpha; Reactive Oxygen Species; Synovial Membrane; Transcription Factor RelA; Vorinostat | 2016 |
Niclosamide induces apoptosis in human rheumatoid arthritis fibroblast-like synoviocytes.
Topics: Acetylcysteine; Apoptosis; Arthritis, Rheumatoid; bcl-2-Associated X Protein; Caspase 3; Caspase 9; Cells, Cultured; Fibroblasts; Gene Expression Regulation; Humans; Niclosamide; Oncogene Protein v-akt; Proto-Oncogene Proteins c-bcl-2; Reactive Oxygen Species; Synovial Membrane | 2016 |
Oridonin Inhibits Cell Proliferation and Induces Apoptosis in Rheumatoid Arthritis Fibroblast-Like Synoviocytes.
Topics: Acetylcysteine; Amino Acid Chloromethyl Ketones; Apoptosis; Arthritis, Rheumatoid; Caspase 3; Caspase 9; Cell Line; Cell Proliferation; Cell Survival; Cytochromes c; Diterpenes, Kaurane; Extracellular Signal-Regulated MAP Kinases; Fibroblasts; Humans; Interleukin-1beta; JNK Mitogen-Activated Protein Kinases; Membrane Potential, Mitochondrial; Mitochondria; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Poly(ADP-ribose) Polymerases; Reactive Oxygen Species; Synoviocytes | 2016 |
Piperlongumine Suppresses Dendritic Cell Maturation by Reducing Production of Reactive Oxygen Species and Has Therapeutic Potential for Rheumatoid Arthritis.
Topics: Acetylcysteine; Alcohol Oxidoreductases; Animals; Arthritis, Experimental; Arthritis, Rheumatoid; B7-1 Antigen; B7-2 Antigen; CD4-Positive T-Lymphocytes; Cell Differentiation; Cell Proliferation; Collagen; Cytokines; Dendritic Cells; Dioxolanes; Disease Models, Animal; Glutathione S-Transferase pi; Interferon-gamma; Interleukin-12; Interleukin-6; Mice; Reactive Oxygen Species; Signal Transduction | 2016 |
N-acetyl-l-cysteine controls osteoclastogenesis through regulating Th17 differentiation and RANKL production in rheumatoid arthritis.
Topics: Acetylcysteine; Adult; Aged; Arthritis, Rheumatoid; Cell Differentiation; Fibroblasts; Humans; In Vitro Techniques; Interleukin-17; Middle Aged; Osteogenesis; RANK Ligand; Signal Transduction; Synovial Membrane; Th17 Cells | 2019 |
Cleavage of p53-vimentin complex enhances tumor necrosis factor-related apoptosis-inducing ligand-mediated apoptosis of rheumatoid arthritis synovial fibroblasts.
Topics: Acetylcysteine; Antibodies; Apoptosis; Apoptosis Regulatory Proteins; Arthritis, Rheumatoid; Biological Transport; Caspase Inhibitors; Caspases; Cell Nucleus; Cells, Cultured; Cytoplasm; Cytosol; Enzyme Activation; Fibroblasts; Humans; Membrane Glycoproteins; Proteasome Endopeptidase Complex; Receptors, TNF-Related Apoptosis-Inducing Ligand; Receptors, Tumor Necrosis Factor; Signal Transduction; Synovial Membrane; Tissue Distribution; TNF-Related Apoptosis-Inducing Ligand; Tumor Necrosis Factor-alpha; Tumor Suppressor Protein p53; Ubiquitin; Vimentin | 2005 |
Low dose methotrexate induces apoptosis with reactive oxygen species involvement in T lymphocytic cell lines to a greater extent than in monocytic lines.
Topics: Acetylcysteine; Annexin A5; Anti-Inflammatory Agents; Antimetabolites, Antineoplastic; Antioxidants; Apoptosis; Arthritis, Rheumatoid; Biological Assay; Cell Line, Tumor; Cell Proliferation; Cell Survival; Enzyme Inhibitors; Fluorescein-5-isothiocyanate; Fluorescent Dyes; Humans; Immunosuppressive Agents; Jurkat Cells; Leukocytes; Methotrexate; Monocytes; Oxidative Stress; Propidium; Reactive Oxygen Species; T-Lymphocytes; Tetrazolium Salts; Thiazoles; Time Factors; U937 Cells | 2005 |
Vanadate, an inhibitor of stromelysin and collagenase expression, suppresses collagen induced arthritis.
Topics: Acetylcysteine; Animals; Ankle Joint; Arthritis, Experimental; Arthritis, Rheumatoid; Collagenases; Disease Models, Animal; Drug Evaluation, Preclinical; Enzyme Inhibitors; Female; Injections, Subcutaneous; Interleukin-1; Matrix Metalloproteinase 3; Pyrones; Random Allocation; Rats; Vanadates | 2007 |
Hematologic reactions to chrysotherapy treated with iv N-acetylcysteine.
Topics: Acetylcysteine; Adult; Arthritis, Rheumatoid; Drug Hypersensitivity; Female; Gold Sodium Thiomalate; Hematologic Diseases; Humans | 1984 |
Antioxidants inhibit tumor necrosis factor-alpha mediated stimulation of interleukin-8, monocyte chemoattractant protein-1, and collagenase expression in cultured human synovial cells.
Topics: Acetylcysteine; Antioxidants; Arthritis, Rheumatoid; Cells, Cultured; Chemokine CCL2; Collagenases; Free Radical Scavengers; Gene Expression Regulation, Enzymologic; Humans; Hydrogen Peroxide; Interleukin-8; NF-kappa B; Pyrrolidonecarboxylic Acid; RNA, Messenger; Synovial Membrane; Thiazoles; Thiazolidines; Transcription, Genetic; Tumor Necrosis Factor-alpha | 1996 |
Induction of cytokines and ICAM-1 by proinflammatory cytokines in primary rheumatoid synovial fibroblasts and inhibition by N-acetyl-L-cysteine and aspirin.
Topics: Acetylcysteine; Arthritis, Rheumatoid; Aspirin; Cells, Cultured; Cytokines; Fibroblasts; Humans; Intercellular Adhesion Molecule-1; Interleukin-1; NF-kappa B; Synovial Membrane; Tumor Necrosis Factor-alpha | 1996 |
The role of N-acetylcysteine in protecting synovial fluid biomolecules against radiolytically-mediated oxidative damage: a high field proton NMR study.
Topics: Acetylcysteine; Arthritis, Rheumatoid; Cysteine; Free Radicals; Gamma Rays; Humans; Knee Joint; Magnetic Resonance Spectroscopy; Oxidative Stress; Protons; Sulfhydryl Compounds; Synovial Fluid | 1999 |
A novel role for interleukin-18 in adhesion molecule induction through NF kappa B and phosphatidylinositol (PI) 3-kinase-dependent signal transduction pathways.
Topics: Acetylcysteine; Antibodies, Monoclonal; Antioxidants; Arthritis, Rheumatoid; Cell Adhesion; E-Selectin; Endothelium, Vascular; Fibroblasts; HL-60 Cells; Humans; Intercellular Adhesion Molecule-1; Interleukin-18; NF-kappa B; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Pyrrolidines; Signal Transduction; Synovial Fluid; Thiocarbamates; Vascular Cell Adhesion Molecule-1 | 2001 |
Effects of oral N-acetylcysteine on gold levels in rheumatoid arthritis.
Topics: Acetylcysteine; Aged; Arthritis, Rheumatoid; Female; Gold; Humans; Male; Middle Aged | 1990 |
Measurement of penicillamine and N-acetylcysteine in human blood by high-performance liquid chromatography and electrochemical detection.
Topics: Acetylcysteine; Arthritis, Rheumatoid; Chromatography, High Pressure Liquid; Drug Stability; Electrochemistry; Humans; Kinetics; Penicillamine; Sulfhydryl Compounds | 1986 |
Gold induced aplastic anemia. Complete response to corticosteroids, plasmapheresis, and N-acetylcysteine infusion.
Topics: Acetylcysteine; Anemia, Aplastic; Arthritis, Rheumatoid; Bone Marrow; Female; Gold; Humans; Middle Aged; Plasmapheresis; Prednisone | 1985 |
Acetylcysteine treatment of keratitis sicca.
Topics: Acetylcysteine; Aged; Arthritis, Rheumatoid; Chronic Disease; Contact Lenses, Hydrophilic; Eyelid Diseases; Female; Humans; Keratoconjunctivitis; Lubrication; Ophthalmic Solutions; Spasm; Visual Acuity | 1971 |
Acetylcysteine in kerato-conjunctivitis sicca.
Topics: Acetylcysteine; Adolescent; Adult; Aged; Arthritis, Rheumatoid; Child; Child, Preschool; Cornea; Female; Humans; Keratoconjunctivitis; Lacrimal Apparatus; Male; Methylcellulose; Middle Aged; Mucus; Salivary Glands; Sarcoidosis; Tears; Xerostomia | 1968 |