1-(5-isoquinolinesulfonyl)-2-methylpiperazine has been researched along with Rheumatoid Arthritis in 4 studies
1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine: A specific protein kinase C inhibitor, which inhibits superoxide release from human neutrophils (PMN) stimulated with phorbol myristate acetate or synthetic diacylglycerol.
1-(5-isoquinolinesulfonyl)-2-methylpiperazine : A member of the class of N-sulfonylpiperazines that is 2-methylpiperazine substituted at position 1 by a 5-isoquinolinesulfonyl group.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Pernis, AB | 1 |
| Ricker, E | 1 |
| Weng, CH | 1 |
| Rozo, C | 1 |
| Yi, W | 1 |
| He, Y | 1 |
| Xu, H | 1 |
| Liang, L | 1 |
| Zhan, Z | 1 |
| Yang, X | 1 |
| Yu, X | 1 |
| Ye, Y | 1 |
| Sun, L | 1 |
| Okamoto, H | 1 |
| Yoshio, T | 1 |
| Kaneko, H | 1 |
| Yamanaka, H | 1 |
| Migita, K | 1 |
| Eguchi, K | 1 |
| Tsukada, T | 1 |
| Kawabe, Y | 1 |
| Aoyagi, T | 1 |
| Nagataki, S | 1 |
1 review available for 1-(5-isoquinolinesulfonyl)-2-methylpiperazine and Rheumatoid Arthritis
| Article | Year |
|---|---|
Rho Kinases in Autoimmune Diseases.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Amides; Animals; Arthritis, Rheumatoid; Autoimmune Di | 2016 |
3 other studies available for 1-(5-isoquinolinesulfonyl)-2-methylpiperazine and Rheumatoid Arthritis
| Article | Year |
|---|---|
Antiinflammatory effect of Rho kinase blockade via inhibition of NF-kappaB activation in rheumatoid arthritis.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Aged; Amides; Animals; Arthritis, Experimental; Arthr | 2008 |
Inhibition of NF-kappaB signaling by fasudil as a potential therapeutic strategy for rheumatoid arthritis.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Arthritis, Experimental; Arthritis, Rheumato | 2010 |
The role of protein kinase in human synovial fibroblast growth.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Arthritis, Rheumatoid; Benzoquinones; Calcium-Calmodu | 1995 |