hydroxyurea has been researched along with Rheumatoid Arthritis in 18 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| " Since Zileuton, also an inhibitor of 5-LOX, attenuates asthma but with an undesirable side effect, we investigated whether dietary GLA would suppress biosynthesis of PMN-LTB4 isolated from asthma patients and attenuate asthma." | 9.11 | Suppression of leukotriene B4 generation by ex-vivo neutrophils isolated from asthma patients on dietary supplementation with gammalinolenic acid-containing borage oil: possible implication in asthma. ( Gershwin, ME; Morrissey, BM; Naguwa, S; Vang, K; Watnik, M; Wineinger, J; Ziboh, VA, 2004) |
| "To obtain preliminary evidence on the safety and efficacy of low dose hydroxyurea as a treatment for rheumatoid arthritis (RA)." | 9.08 | A preliminary evaluation of hydroxyurea for the treatment of rheumatoid arthritis. ( Albert, DA; Ehrlich, LS; Thalji, K; Whitman, K, 1995) |
| "The effects of zileuton, a new 5-lipoxygenase inhibitor, on leukotriene generation and clinical response in rheumatoid arthritis (RA) was studied in a 4-week randomized double blind placebo controlled study at 2 academic rheumatology centers." | 9.07 | Zileuton, a 5-lipoxygenase inhibitor in rheumatoid arthritis. ( Coblyn, JS; Helfgott, S; Henson, B; Kremer, JM; Maier, AL; Petrillo, G; Rubin, P; Sperling, R; Weinblatt, ME, 1992) |
| " Since Zileuton, also an inhibitor of 5-LOX, attenuates asthma but with an undesirable side effect, we investigated whether dietary GLA would suppress biosynthesis of PMN-LTB4 isolated from asthma patients and attenuate asthma." | 5.11 | Suppression of leukotriene B4 generation by ex-vivo neutrophils isolated from asthma patients on dietary supplementation with gammalinolenic acid-containing borage oil: possible implication in asthma. ( Gershwin, ME; Morrissey, BM; Naguwa, S; Vang, K; Watnik, M; Wineinger, J; Ziboh, VA, 2004) |
| "The pharmacokinetics of zileuton, a novel selective 5-lipoxygenase inhibitor, were studied in 37 patients with rheumatoid arthritis after administration of 200 mg, 400 mg, and 600 mg, zileuton for 4 weeks." | 5.08 | Population pharmacokinetics of zileution, a selective 5-lipoxygenase inhibitor, in patients with rheumatoid arthritis. ( Awni, WM; Brandwein, SR; Dube, LM; Granneman, GR; Locke, CS, 1995) |
| "To obtain preliminary evidence on the safety and efficacy of low dose hydroxyurea as a treatment for rheumatoid arthritis (RA)." | 5.08 | A preliminary evaluation of hydroxyurea for the treatment of rheumatoid arthritis. ( Albert, DA; Ehrlich, LS; Thalji, K; Whitman, K, 1995) |
| "The effects of zileuton, a new 5-lipoxygenase inhibitor, on leukotriene generation and clinical response in rheumatoid arthritis (RA) was studied in a 4-week randomized double blind placebo controlled study at 2 academic rheumatology centers." | 5.07 | Zileuton, a 5-lipoxygenase inhibitor in rheumatoid arthritis. ( Coblyn, JS; Helfgott, S; Henson, B; Kremer, JM; Maier, AL; Petrillo, G; Rubin, P; Sperling, R; Weinblatt, ME, 1992) |
| "An electronic search encompassing MEDLINE, PubMed, Cochrane Library, and Scopus was completed using the following search terms: rheumatoid arthritis; systemic sclerosis; systemic lupus erythematosus; antineutrophil cytoplasmic antibody-associated vasculitis; mixed connective tissue disease; antiphospholipid syndrome; pyoderma gangrenosum; thromboangiitis obliterans; cryoglobulinemia; hydroxyurea; sickle cell; atrophie blanche; livedoid vasculitis; cholesterol emboli; calciphylaxis; antiphospholipid antibodies; prothrombotic; combined with the terms: chronic wound and leg ulcer." | 4.95 | Vasculitic and autoimmune wounds. ( Angra, D; McNish, S; Rahimi, H; Shanmugam, VK, 2017) |
| " Eosinophilic esophagitis and pharyngitis were diagnosed, and the patient was administered corticosteroids and hydroxyurea, following which her symptoms resolved." | 3.78 | Eosinophilic esophagitis and pharyngitis presenting as mass lesion in a patient with inactive rheumatoid arthritis. ( Danda, D; Kurian, S; Mathew, J; Ramakrishna, BS; Sandhya, P, 2012) |
| " After their base-line blood levels had been assessed, 3 patients with classical rheumatoid arthritis (according to ARA criteria; American Rheumatism Association) received 500 mg of d-2-(6'-methoxy-2'-naphthyl)-propionic acid (naproxen) daily (in capsules)." | 3.65 | [Effect of naproxen on DNA synthesis and DNA repair of human lymphocytes in in vivo experiments]. ( Tausch, G, 1975) |
| "Rheumatoid arthritis was considered for centuries to be a nuisance condition, limiting in its effects on an individual's range of motion and the source of considerable distress, but not a life-threatening disease." | 2.40 | Emerging treatments for rheumatoid arthritis. ( Schiff, M, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (11.11) | 18.7374 |
| 1990's | 9 (50.00) | 18.2507 |
| 2000's | 3 (16.67) | 29.6817 |
| 2010's | 4 (22.22) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Shallis, RM | 1 |
| Xu, ML | 1 |
| Curtis, SA | 1 |
| Medoff, E | 1 |
| Mixon, R | 1 |
| Folkers, A | 1 |
| Zeidan, AM | 1 |
| Shanmugam, VK | 1 |
| Angra, D | 1 |
| Rahimi, H | 1 |
| McNish, S | 1 |
| Anderson, GD | 1 |
| Keys, KL | 1 |
| De Ciechi, PA | 1 |
| Masferrer, JL | 1 |
| Ayvaz, OC | 1 |
| Yavasoglu, I | 1 |
| Kadikoylu, G | 1 |
| Bozkurt, G | 1 |
| Bolaman, Z | 1 |
| Sandhya, P | 1 |
| Danda, D | 1 |
| Mathew, J | 1 |
| Kurian, S | 1 |
| Ramakrishna, BS | 1 |
| Ziboh, VA | 1 |
| Naguwa, S | 1 |
| Vang, K | 1 |
| Wineinger, J | 1 |
| Morrissey, BM | 1 |
| Watnik, M | 1 |
| Gershwin, ME | 1 |
| Michel, M | 1 |
| Habibi, A | 1 |
| Godeau, B | 1 |
| Bachir, D | 1 |
| Lahary, A | 1 |
| Galacteros, F | 1 |
| Fifi-Mah, A | 1 |
| Arfi, S | 1 |
| Awni, WM | 1 |
| Granneman, GR | 1 |
| Locke, CS | 1 |
| Brandwein, SR | 1 |
| Dube, LM | 1 |
| Ehrlich, LS | 1 |
| Thalji, K | 1 |
| Whitman, K | 1 |
| Albert, DA | 1 |
| McGill, KA | 1 |
| Busse, WW | 1 |
| Morris, AJ | 1 |
| Russell, AS | 1 |
| Ramos-Remus, C | 1 |
| Schiff, M | 1 |
| Santais, MC | 1 |
| Callens, E | 1 |
| Djebbar, R | 1 |
| Ruff, F | 1 |
| Navarra, P | 1 |
| Preziosi, P | 1 |
| Brzezińska, B | 1 |
| Graff-Wróblewska, T | 1 |
| Juszczyk, T | 1 |
| Tausch, G | 1 |
| Weinblatt, ME | 1 |
| Kremer, JM | 1 |
| Coblyn, JS | 1 |
| Helfgott, S | 1 |
| Maier, AL | 1 |
| Petrillo, G | 1 |
| Henson, B | 1 |
| Rubin, P | 1 |
| Sperling, R | 1 |
6 reviews available for hydroxyurea and Rheumatoid Arthritis
| Article | Year |
|---|---|
Conviction in the face of affliction: a case series of Jehovah's Witnesses with myeloid malignancies.
Topics: Aged; Anemia, Macrocytic; Antimetabolites, Antineoplastic; Arthritis, Rheumatoid; Azacitidine; Blood | 2018 |
Vasculitic and autoimmune wounds.
Topics: Anemia, Sickle Cell; Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis; Antiphospholipid Sy | 2017 |
Zileuton.
Topics: Arthritis, Rheumatoid; Asthma; Humans; Hydroxyurea; Lipoxygenase Inhibitors | 1996 |
Emerging treatments for rheumatoid arthritis.
Topics: Adrenal Cortex Hormones; Anti-Inflammatory Agents, Non-Steroidal; Antibodies; Antirheumatic Agents; | 1997 |
[Potential importance of antileukotrienes in the treatment of asthma and other inflammatory diseases: apropos of a new pharmacological class].
Topics: Acetophenones; Adult; Animals; Anti-Asthmatic Agents; Anti-Inflammatory Agents, Non-Steroidal; Arthr | 1998 |
Hydroxyurea: new insights on an old drug.
Topics: Arthritis, Rheumatoid; Hematologic Diseases; Humans; Hydroxyurea; Neoplasms; Ribonucleotide Reductas | 1999 |
4 trials available for hydroxyurea and Rheumatoid Arthritis
| Article | Year |
|---|---|
Suppression of leukotriene B4 generation by ex-vivo neutrophils isolated from asthma patients on dietary supplementation with gammalinolenic acid-containing borage oil: possible implication in asthma.
Topics: Adult; Aged; Arthritis, Rheumatoid; Asthma; Dietary Supplements; Double-Blind Method; Fatty Acids; F | 2004 |
Population pharmacokinetics of zileution, a selective 5-lipoxygenase inhibitor, in patients with rheumatoid arthritis.
Topics: Administration, Oral; Adolescent; Adult; Aged; Arthritis, Rheumatoid; Female; Humans; Hydroxyurea; K | 1995 |
A preliminary evaluation of hydroxyurea for the treatment of rheumatoid arthritis.
Topics: Adult; Aged; Antirheumatic Agents; Arthritis, Rheumatoid; Humans; Hydroxyurea; Middle Aged; Pilot Pr | 1995 |
Zileuton, a 5-lipoxygenase inhibitor in rheumatoid arthritis.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Double-Blind Method; Fe | 1992 |
8 other studies available for hydroxyurea and Rheumatoid Arthritis
| Article | Year |
|---|---|
Combination therapies that inhibit cyclooxygenase-2 and leukotriene synthesis prevent disease in murine collagen induced arthritis.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arachidonate 5-Lipoxygenase; Arthritis, Experiment | 2009 |
Thrombocytosis in rheumatoid arthritis: JAK2V617F-positive essential thrombocythemia.
Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Aspirin; Comorbidity; Humans; Hydroxyurea; Janus Kinase | 2012 |
Eosinophilic esophagitis and pharyngitis presenting as mass lesion in a patient with inactive rheumatoid arthritis.
Topics: Adult; Arthritis, Rheumatoid; Deglutition Disorders; Drug Therapy, Combination; Eosinophilic Esophag | 2012 |
Characteristics and outcome of connective tissue diseases in patients with sickle-cell disease: report of 30 cases.
Topics: Adult; Anemia, Sickle Cell; Antisickling Agents; Arthritis, Rheumatoid; Blood Transfusion; Drug Ther | 2008 |
Combination drug therapy in rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Drug Therapy, Combination; Humans; Hydroxyurea | 1996 |
Combination drug therapy in rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Chelation Therapy; Drug Therapy, Combination; Humans; Hydroxyurea | 1997 |
[Evaluation of therapeutic value of hydroxycarbamid "Polfa" (hydroxyurea) in rheumatoid arthritis].
Topics: Aged; Arthritis, Rheumatoid; Drug Evaluation; Drug Industry; Female; Humans; Hydroxyurea; Male; Midd | 1978 |
[Effect of naproxen on DNA synthesis and DNA repair of human lymphocytes in in vivo experiments].
Topics: Arthritis, Rheumatoid; Chronic Disease; Cobalt Radioisotopes; DNA; DNA Repair; Humans; Hydroxyurea; | 1975 |