Page last updated: 2024-09-04

cox 189 and Rheumatoid Arthritis

cox 189 has been researched along with Rheumatoid Arthritis in 15 studies

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's14 (93.33)29.6817
2010's1 (6.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bartzatt, R1
Huff, JP; Kalbag, J; Looby, M; Milosavljev, S; Reynolds, C; Rordorf, C; Ruff, DA; Scott, G; Weaver, M1
Gimona, A; Hawkey, C; Kivitz, AJ; Nayiager, S; Schimansky, T; Thurston, HJ1
Branson, JM; Chales, GH; Hartmann, SN; Juvin, RR; Lafforgue, P; Le Parc, JM; Meyer, OC; Milosavljev, S; Rordorf, CM; Tavernier, CG1
Curran, MP; Lyseng-Williamson, KA1
Alten, R; Geusens, P; Kralidis, G; Krammer, G; Richardson, P; Rovensky, J; Sloan, VS1
Doggrell, SA1
Gitton, X; Jayawardene, S; Schnitzer, TJ; Sloan, VS1
Bannwarth, B; Berenbaum, F1
Hochberg, MC1
Ehrsam, E; Garaud, JJ; Gitton, X; Hoexter, G; Krammer, G; Matchaba, P; Mellein, B; Olson, M; Orloff, J; Sloan, VS1
Choi, L; Mangold, JB; Marshall, P; Rordorf, CM1
Gitton, X; Hawkey, CJ; Hoexter, G; Richard, D; Weinstein, WM1
Baraf, HS1
Klotz, U; Shi, S1

Reviews

8 review(s) available for cox 189 and Rheumatoid Arthritis

ArticleYear
The safety of lumiracoxib when used in the treatment of arthritis.
    Expert opinion on pharmacotherapy, 2005, Volume: 6, Issue:2

    Topics: Arthritis, Rheumatoid; Cardiovascular Diseases; Cyclooxygenase 2 Inhibitors; Diclofenac; Humans; Organic Chemicals; Stomach Ulcer

2005
Clinical pharmacology of lumiracoxib, a second-generation cyclooxygenase 2 selective inhibitor.
    Expert opinion on investigational drugs, 2005, Volume: 14, Issue:4

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Cyclooxygenase 2 Inhibitors; Diclofenac; Dysmenorrhea; Female; Gastrointestinal Hemorrhage; Humans; Osteoarthritis; Pain, Postoperative; Randomized Controlled Trials as Topic

2005
COX-2 selective inhibitors in the treatment of arthritis: a rheumatologist perspective.
    Current topics in medicinal chemistry, 2005, Volume: 5, Issue:5

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Celecoxib; Cost-Benefit Analysis; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Diclofenac; Etoricoxib; Humans; Isoxazoles; Lactones; Membrane Proteins; Organic Chemicals; Osteoarthritis; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Pyridines; Randomized Controlled Trials as Topic; Rheumatology; Sulfonamides; Sulfones; Treatment Outcome

2005
Cardiovascular safety of lumiracoxib: a meta-analysis of all randomized controlled trials > or =1 week and up to 1 year in duration of patients with osteoarthritis and rheumatoid arthritis.
    Clinical therapeutics, 2005, Volume: 27, Issue:8

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Cardiovascular Diseases; Cyclooxygenase 2 Inhibitors; Databases, Factual; Diclofenac; Female; Humans; Male; Middle Aged; Organic Chemicals; Osteoarthritis; Randomized Controlled Trials as Topic

2005
Clinical pharmacology of lumiracoxib: a selective cyclo-oxygenase-2 inhibitor.
    Clinical pharmacokinetics, 2005, Volume: 44, Issue:12

    Topics: Arthritis, Rheumatoid; Clinical Trials as Topic; Cyclooxygenase 2 Inhibitors; Diclofenac; Humans; Kidney Diseases; Liver Diseases; Organic Chemicals; Osteoarthritis

2005
Gastrointestinal tolerability of lumiracoxib in patients with osteoarthritis and rheumatoid arthritis.
    Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 2006, Volume: 4, Issue:1

    Topics: Aged; Arthritis, Rheumatoid; Cyclooxygenase 2 Inhibitors; Diclofenac; Female; Gastrointestinal Diseases; Humans; Male; Middle Aged; Organic Chemicals; Osteoarthritis; Randomized Controlled Trials as Topic

2006
Efficacy of the newest COX-2 selective inhibitors in rheumatic disease.
    Current pharmaceutical design, 2007, Volume: 13, Issue:22

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Gouty; Arthritis, Rheumatoid; Cardiovascular Diseases; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Diclofenac; Etoricoxib; Gastrointestinal Hemorrhage; Humans; Membrane Proteins; Osteoarthritis; Patient Selection; Pyridines; Rheumatic Diseases; Risk Assessment; Risk Factors; Spondylitis, Ankylosing; Sulfones

2007
Clinical use and pharmacological properties of selective COX-2 inhibitors.
    European journal of clinical pharmacology, 2008, Volume: 64, Issue:3

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Celecoxib; Cyclooxygenase 2 Inhibitors; Diclofenac; Drug Monitoring; Etoricoxib; Humans; Osteoarthritis; Pain; Pyrazoles; Pyridines; Sulfonamides; Sulfones

2008

Trials

5 trial(s) available for cox 189 and Rheumatoid Arthritis

ArticleYear
Pharmacokinetics of lumiracoxib in plasma and synovial fluid.
    Clinical pharmacokinetics, 2004, Volume: 43, Issue:7

    Topics: Administration, Oral; Adult; Aged; Area Under Curve; Arthritis, Rheumatoid; Cyclooxygenase Inhibitors; Diclofenac; Female; Half-Life; Humans; Male; Metabolic Clearance Rate; Middle Aged; Organic Chemicals; Synovial Fluid; Tissue Distribution

2004
Reduced incidence of gastroduodenal ulcers associated with lumiracoxib compared with ibuprofen in patients with rheumatoid arthritis.
    Alimentary pharmacology & therapeutics, 2004, Jun-01, Volume: 19, Issue:11

    Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Cyclooxygenase Inhibitors; Diclofenac; Double-Blind Method; Humans; Ibuprofen; Middle Aged; Organic Chemicals; Peptic Ulcer; Treatment Outcome

2004
Lumiracoxib does not affect methotrexate pharmacokinetics in rheumatoid arthritis patients.
    The Annals of pharmacotherapy, 2004, Volume: 38, Issue:10

    Topics: Adolescent; Adult; Aged; Antirheumatic Agents; Arthritis, Rheumatoid; Cross-Over Studies; Cyclooxygenase 2; Diclofenac; Dose-Response Relationship, Drug; Double-Blind Method; Drug Interactions; Female; Humans; Isoenzymes; Male; Membrane Proteins; Methotrexate; Middle Aged; Organic Chemicals; Prostaglandin-Endoperoxide Synthases

2004
Lumiracoxib.
    Drugs, 2004, Volume: 64, Issue:19

    Topics: Administration, Oral; Arthritis, Rheumatoid; Celecoxib; Cyclooxygenase Inhibitors; Diclofenac; Double-Blind Method; Drug Administration Schedule; Drug Evaluation, Preclinical; Female; Half-Life; Humans; Male; Molecular Structure; New Zealand; Organic Chemicals; Osteoarthritis; Oxycodone; Pain; Pyrazoles; Sulfonamides; Terminology as Topic; World Health Organization

2004
Efficacy, safety and tolerability of lumiracoxib in patients with rheumatoid arthritis.
    International journal of clinical practice, 2004, Volume: 58, Issue:11

    Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis, Rheumatoid; Diclofenac; Double-Blind Method; Female; Humans; Male; Middle Aged; Naproxen; Organic Chemicals; Pain Measurement; Treatment Outcome

2004

Other Studies

2 other study(ies) available for cox 189 and Rheumatoid Arthritis

ArticleYear
Drug analogs of COX-2 selective inhibitors lumiracoxib and valdecoxib derived from in silico search and optimization.
    Anti-inflammatory & anti-allergy agents in medicinal chemistry, 2014, Volume: 13, Issue:1

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Computer Simulation; Cyclooxygenase 2 Inhibitors; Diclofenac; Drug Design; Humans; Isoxazoles; Models, Molecular; Neoplasms; Pain; Sulfonamides

2014
Lumiracoxib in the treatment of osteoarthritis, rheumatoid arthritis and acute postoperative dental pain: results of three dose-response studies.
    Current medical research and opinion, 2005, Volume: 21, Issue:1

    Topics: Adolescent; Adult; Aged; Analysis of Variance; Arthritis, Rheumatoid; Clinical Trials, Phase II as Topic; Cyclooxygenase Inhibitors; Diclofenac; Dose-Response Relationship, Drug; Female; Humans; Logistic Models; Male; Middle Aged; Multicenter Studies as Topic; Organic Chemicals; Osteoarthritis; Pain, Postoperative; Randomized Controlled Trials as Topic; Tooth Extraction; Treatment Outcome

2005