aminopterin has been researched along with Rheumatoid Arthritis in 16 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (37.50) | 18.7374 |
| 1990's | 4 (25.00) | 18.2507 |
| 2000's | 2 (12.50) | 29.6817 |
| 2010's | 3 (18.75) | 24.3611 |
| 2020's | 1 (6.25) | 2.80 |
| Authors | Studies |
|---|---|
| Andresen, TL; Bondebjerg, J; Clausen, MH; Hansen, AE; Hansen, CA; Peiró Cadahía, J; Previtali, V | 1 |
| Clausen, MH; Peiró Cadahía, J; Petrovic, K; Previtali, V; Troelsen, NS | 1 |
| Haile, WH; McGuire, JJ | 1 |
| Bajpai, M | 1 |
| Hewitt, LA; Keystone, EC; Pedder, S; Shirinsky, VS; Simon, LS | 1 |
| COTE, L; GUBNER, R; HUGHES, J; OLESON, JJ; RUEGSEGGER, JM; WILLIAMS, JH | 1 |
| AUGUST, S; GINSBERG, V; GUBNER, R | 1 |
| Castaneda, O; Nair, MG | 1 |
| Colwell, WT; Crase, J; DeGraw, JI; Piper, JR; Sirotnak, FM; Smith, RL; Waud, WR | 1 |
| Colwell, WT; DeGraw, JI; Johnson, CA; Piper, JR; Sirotnak, FM; Smith, RL; Waud, WR | 1 |
| Gubner, RS | 1 |
| Alarcón, GS; Castañeda, O; Ferrándiz, M; Koopman, WJ; Krumdieck, CL | 1 |
| Alarcón, GS; Castañeda, O; Ferrándiz, M; Koopman, WJ; Krumdieck, CL; Nair, MG | 1 |
| Ward, JR | 1 |
| Currey, HL | 2 |
3 review(s) available for aminopterin and Rheumatoid Arthritis
| Article | Year |
|---|---|
CH-1504, a metabolically inert antifolate for the potential treatment of rheumatoid arthritis.
Topics: Aminopterin; Animals; Antirheumatic Agents; Arthritis, Rheumatoid; Folic Acid Antagonists; Humans | 2010 |
Immunosuppressive drugs in rheumatoid arthritis.
Topics: Adrenocorticotropic Hormone; Aminopterin; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Autoimmune Diseases; Azathioprine; Chlorambucil; Clinical Trials as Topic; Cyclophosphamide; Humans; Immunosuppressive Agents; Mercaptopurine; Methotrexate; Nitrogen Mustard Compounds; Penicillamine | 1971 |
Treatment of rheumatoid arthritis with cytotoxic and antimetabolic drugs.
Topics: Alopecia; Aminopterin; Antimetabolites; Antineoplastic Agents; Arthritis, Rheumatoid; Azathioprine; Bone Marrow Diseases; Chlorambucil; Clinical Trials as Topic; Cyclophosphamide; Cystitis; Female; Herpes Zoster; Humans; Jaundice; Mechlorethamine; Mercaptopurine; Methotrexate | 1970 |
7 trial(s) available for aminopterin and Rheumatoid Arthritis
| Article | Year |
|---|---|
Efficacy and safety of CH-1504, a metabolically stable antifolate, in patients with active rheumatoid arthritis: results of a phase II multicenter randomized study.
Topics: Adult; Aged; Aged, 80 and over; Aminopterin; Antirheumatic Agents; Arthritis, Rheumatoid; Female; Folic Acid Antagonists; Humans; Male; Methotrexate; Middle Aged; Treatment Outcome; Young Adult | 2011 |
Controlled trial of methotrexate versus CH-1504 in the treatment of rheumatoid arthritis.
Topics: Adult; Aged; Aminopterin; Antirheumatic Agents; Arthritis, Rheumatoid; Female; Folic Acid Antagonists; Gastrointestinal Tract; Humans; Liver; Liver Function Tests; Male; Methotrexate; Middle Aged | 2006 |
Efficacy and safety of 10-deazaaminopterin in the treatment of rheumatoid arthritis. A one-year continuation, double-blind study.
Topics: Adult; Alkaline Phosphatase; Aminopterin; Arthritis, Rheumatoid; Aspartate Aminotransferases; Double-Blind Method; Female; Folic Acid; Humans; Male; Methotrexate; Middle Aged | 1992 |
Controlled trial of methotrexate versus 10-deazaaminopterin in the treatment of rheumatoid arthritis.
Topics: Aminopterin; Arthritis, Rheumatoid; Double-Blind Method; Folic Acid Antagonists; Humans; Methotrexate; Middle Aged; Treatment Outcome | 1992 |
Historical perspective on the use of methotrexate for the treatment of rheumatoid arthritis.
Topics: Adult; Aged; Aminopterin; Arthritis, Rheumatoid; Chemical and Drug Induced Liver Injury; Clinical Trials as Topic; Double-Blind Method; Female; History, 20th Century; Humans; Male; Methotrexate; Pneumonia; Psoriasis; Random Allocation | 1985 |
Immunosuppressive drugs in rheumatoid arthritis.
Topics: Adrenocorticotropic Hormone; Aminopterin; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Autoimmune Diseases; Azathioprine; Chlorambucil; Clinical Trials as Topic; Cyclophosphamide; Humans; Immunosuppressive Agents; Mercaptopurine; Methotrexate; Nitrogen Mustard Compounds; Penicillamine | 1971 |
Treatment of rheumatoid arthritis with cytotoxic and antimetabolic drugs.
Topics: Alopecia; Aminopterin; Antimetabolites; Antineoplastic Agents; Arthritis, Rheumatoid; Azathioprine; Bone Marrow Diseases; Chlorambucil; Clinical Trials as Topic; Cyclophosphamide; Cystitis; Female; Herpes Zoster; Humans; Jaundice; Mechlorethamine; Mercaptopurine; Methotrexate | 1970 |
8 other study(ies) available for aminopterin and Rheumatoid Arthritis
| Article | Year |
|---|---|
Synthesis and Evaluation of Hydrogen Peroxide Sensitive Prodrugs of Methotrexate and Aminopterin for the Treatment of Rheumatoid Arthritis.
Topics: Aminopterin; Animals; Antirheumatic Agents; Arthritis, Experimental; Arthritis, Rheumatoid; Boronic Acids; Collagen Type II; Humans; Hydrogen Peroxide; Male; MCF-7 Cells; Methotrexate; Mice, Inbred DBA; Microsomes, Liver; Prodrugs; Solubility | 2018 |
Auxiliary in vitro and in vivo biological evaluation of hydrogen peroxide sensitive prodrugs of methotrexate and aminopterin for the treatment of rheumatoid arthritis.
Topics: Aminopterin; Animals; Antirheumatic Agents; Apoptosis; Arthritis, Experimental; Arthritis, Rheumatoid; Cell Proliferation; Cell Survival; Disease Models, Animal; Dose-Response Relationship, Drug; Hydrogen Peroxide; Injections, Intraperitoneal; Methotrexate; Molecular Structure; Prodrugs; Rats; Reactive Oxygen Species; Structure-Activity Relationship | 2020 |
Metabolism-blocked antifolates as potential anti-rheumatoid arthritis agents: 4-amino-4-deoxy-5,8,10-trideazapteroyl-d,l-4'-methyleneglutamic acid (CH-1504) and its analogs.
Topics: Aminopterin; Animals; Antirheumatic Agents; Arthritis, Rheumatoid; Cell Line, Tumor; Folic Acid Antagonists; Humans; Insecta; Metabolic Networks and Pathways; Rabbits | 2009 |
Comparative effects of aminopterin, cortisone and ACTH in experimental formaldehyde arthritis and psoriatic arthritis.
Topics: Adrenocorticotropic Hormone; Aminopterin; Arthritis; Arthritis, Psoriatic; Arthritis, Rheumatoid; Cortisone; Folic Acid Antagonists; Formaldehyde; Humans | 1952 |
Therapeutic suppression of tissue reactivity. II. Effect of aminopterin in rheumatoid arthritis and psoriasis.
Topics: Aminopterin; Arthritis; Arthritis, Rheumatoid; Folic Acid Antagonists; Humans; Psoriasis | 1951 |
Analogues of methotrexate in rheumatoid arthritis. 1. Effects of 10-deazaaminopterin analogues on type II collagen-induced arthritis in mice.
Topics: Aminopterin; Animals; Antirheumatic Agents; Arthritis, Rheumatoid; Cell Line; Cell Survival; Collagen; Humans; Magnetic Resonance Spectroscopy; Mass Spectrometry; Methotrexate; Mice; Molecular Structure; Tumor Cells, Cultured | 1997 |
Analogues of methotrexate in rheumatoid arthritis. 2. Effects of 5-deazaaminopterin, 5,10-dideazaaminopterin, and analogues on type II collagen-induced arthritis in mice.
Topics: Aminopterin; Animals; Antirheumatic Agents; Arthritis, Rheumatoid; Cell Survival; Collagen; Magnetic Resonance Spectroscopy; Mass Spectrometry; Methotrexate; Mice; Mice, Inbred DBA; Molecular Structure; Tumor Cells, Cultured | 1997 |
Introduction of antifolics in psoriasis. A twenty-five year retrospect of antineoplastic agents in nonmalignant disease.
Topics: Adult; Aminopterin; Arthritis, Rheumatoid; Humans; Immunosuppressive Agents; Male; Mechlorethamine; Methotrexate; Psoriasis; Retrospective Studies; Rheumatic Heart Disease | 1979 |