cilostazol has been researched along with Rheumatoid Arthritis in 6 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| " Here, the effects of the phosphodiesterase (PDE) inhibitors vardenafil and cilostazol were examined against rheumatoid arthritis (RA)/diabetes mellitus (DM)-co-morbidity-induced endothelial dysfunction and vascular reactivity defects." | 7.91 | Vardenafil and cilostazol can improve vascular reactivity in rats with diabetes mellitus and rheumatoid arthritis co-morbidity. ( Abo-Saif, AA; El-Daly, ME; Messiha, BAS; Wahba, MGF, 2019) |
| "The present study assessed the effects of cilostazol on LPS-stimulated TLR4 signal pathways in synovial macrophages from patients with rheumatoid arthritis (RA)." | 7.79 | Suppression of PU.1-linked TLR4 expression by cilostazol with decrease of cytokine production in macrophages from patients with rheumatoid arthritis. ( Baek, SH; Hong, KW; Kim, CD; Lee, CW; Lee, SW; Lee, WS; Park, SY; Rhim, BY, 2013) |
| "This study aimed to assess the beneficial effects of the concurrent administration of cilostazol and methotrexate (MTX) on the synovial fibroblasts obtained from patients with rheumatoid arthritis (RA), and in a mouse model of collagen-induced arthritis (CIA)." | 7.78 | Efficacy of concurrent administration of cilostazol and methotrexate in rheumatoid arthritis: pharmacologic and clinical significance. ( Baek, SH; Hong, KW; Kim, CD; Kim, HY; Lee, CW; Lee, SW; Park, SY, 2012) |
| "To assess the effects of cilostazol in inhibiting proliferation and enhancing apoptosis in synovial cells from patients with rheumatoid arthritis (RA)." | 7.76 | Cilostazol enhances apoptosis of synovial cells from rheumatoid arthritis patients with inhibition of cytokine formation via Nrf2-linked heme oxygenase 1 induction. ( Chung, WT; Hong, KW; Kim, CD; Lee, SW; Lee, WS; Park, SY; Rhim, BY; Shin, HK, 2010) |
| " Here, the effects of the phosphodiesterase (PDE) inhibitors vardenafil and cilostazol were examined against rheumatoid arthritis (RA)/diabetes mellitus (DM)-co-morbidity-induced endothelial dysfunction and vascular reactivity defects." | 3.91 | Vardenafil and cilostazol can improve vascular reactivity in rats with diabetes mellitus and rheumatoid arthritis co-morbidity. ( Abo-Saif, AA; El-Daly, ME; Messiha, BAS; Wahba, MGF, 2019) |
| "The present study assessed the effects of cilostazol on LPS-stimulated TLR4 signal pathways in synovial macrophages from patients with rheumatoid arthritis (RA)." | 3.79 | Suppression of PU.1-linked TLR4 expression by cilostazol with decrease of cytokine production in macrophages from patients with rheumatoid arthritis. ( Baek, SH; Hong, KW; Kim, CD; Lee, CW; Lee, SW; Lee, WS; Park, SY; Rhim, BY, 2013) |
| "This study aimed to assess the beneficial effects of the concurrent administration of cilostazol and methotrexate (MTX) on the synovial fibroblasts obtained from patients with rheumatoid arthritis (RA), and in a mouse model of collagen-induced arthritis (CIA)." | 3.78 | Efficacy of concurrent administration of cilostazol and methotrexate in rheumatoid arthritis: pharmacologic and clinical significance. ( Baek, SH; Hong, KW; Kim, CD; Kim, HY; Lee, CW; Lee, SW; Park, SY, 2012) |
| "To assess the effects of cilostazol in inhibiting proliferation and enhancing apoptosis in synovial cells from patients with rheumatoid arthritis (RA)." | 3.76 | Cilostazol enhances apoptosis of synovial cells from rheumatoid arthritis patients with inhibition of cytokine formation via Nrf2-linked heme oxygenase 1 induction. ( Chung, WT; Hong, KW; Kim, CD; Lee, SW; Lee, WS; Park, SY; Rhim, BY; Shin, HK, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 6 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wahba, MGF | 1 |
| Messiha, BAS | 1 |
| El-Daly, ME | 1 |
| Abo-Saif, AA | 1 |
| Park, SY | 5 |
| Lee, SW | 5 |
| Lee, WS | 4 |
| Rhim, BY | 4 |
| Lee, SJ | 1 |
| Kwon, SM | 1 |
| Hong, KW | 5 |
| Kim, CD | 5 |
| Kim, HY | 2 |
| Lee, HR | 1 |
| Shin, HK | 1 |
| Chung, WT | 1 |
| Baek, SH | 2 |
| Lee, CW | 2 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Phosphodiesterase 3 Inhibitor Cilostazol as Adjunct to Methotrexate in Patients With Rheumatoid Arthritis[NCT05594680] | Phase 3 | 70 participants (Anticipated) | Interventional | 2022-10-01 | Recruiting | ||
| Evaluation of the Effect of Cilostazol on the Clinical Outcomes of Rheumatoid Arthritis Patients[NCT05671497] | Phase 2/Phase 3 | 70 participants (Anticipated) | Interventional | 2022-11-01 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
6 other studies available for cilostazol and Rheumatoid Arthritis
| Article | Year |
|---|---|
Vardenafil and cilostazol can improve vascular reactivity in rats with diabetes mellitus and rheumatoid arthritis co-morbidity.
Topics: Animals; Arthritis, Experimental; Arthritis, Rheumatoid; Cardiovascular Diseases; Cilostazol; Comorb | 2019 |
RhoA/ROCK-dependent pathway is required for TLR2-mediated IL-23 production in human synovial macrophages: suppression by cilostazol.
Topics: ADP Ribose Transferases; Amides; Animals; Arthritis, Rheumatoid; Botulinum Toxins; Case-Control Stud | 2013 |
Inhibition of HMGB1-induced angiogenesis by cilostazol via SIRT1 activation in synovial fibroblasts from rheumatoid arthritis.
Topics: Angiogenesis Inhibitors; Animals; Arthritis, Rheumatoid; Cells, Cultured; Cilostazol; Fibroblasts; H | 2014 |
Cilostazol enhances apoptosis of synovial cells from rheumatoid arthritis patients with inhibition of cytokine formation via Nrf2-linked heme oxygenase 1 induction.
Topics: Animals; Anti-Inflammatory Agents; Apoptosis; Arthritis, Experimental; Arthritis, Rheumatoid; Blotti | 2010 |
Efficacy of concurrent administration of cilostazol and methotrexate in rheumatoid arthritis: pharmacologic and clinical significance.
Topics: Animals; Antirheumatic Agents; Apoptosis; Arthritis, Rheumatoid; Base Sequence; Cell Proliferation; | 2012 |
Efficacy of concurrent administration of cilostazol and methotrexate in rheumatoid arthritis: pharmacologic and clinical significance.
Topics: Animals; Antirheumatic Agents; Apoptosis; Arthritis, Rheumatoid; Base Sequence; Cell Proliferation; | 2012 |
Efficacy of concurrent administration of cilostazol and methotrexate in rheumatoid arthritis: pharmacologic and clinical significance.
Topics: Animals; Antirheumatic Agents; Apoptosis; Arthritis, Rheumatoid; Base Sequence; Cell Proliferation; | 2012 |
Efficacy of concurrent administration of cilostazol and methotrexate in rheumatoid arthritis: pharmacologic and clinical significance.
Topics: Animals; Antirheumatic Agents; Apoptosis; Arthritis, Rheumatoid; Base Sequence; Cell Proliferation; | 2012 |
Suppression of PU.1-linked TLR4 expression by cilostazol with decrease of cytokine production in macrophages from patients with rheumatoid arthritis.
Topics: Animals; Antirheumatic Agents; Arthritis, Rheumatoid; Cells, Cultured; Cilostazol; Cytokines; Diseas | 2013 |