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carprofen and Rheumatoid Arthritis

carprofen has been researched along with Rheumatoid Arthritis in 15 studies

carprofen: RN given refers to cpd without isomeric designation
carprofen : Propanoic acid in which one of the methylene hydrogens is substituted by a 6-chloro-9H-carbazol-2-yl group. A non-steroidal anti-inflammatory drug, it is no longer used in human medicine but is still used for treatment of arthritis in elderly dogs.

Research Excerpts

ExcerptRelevanceReference
"Thirty-eight patients with active, definite, or classical rheumatoid arthritis were tested in a double-blind, 3-week-per-arm, multiple-crossover, randomized, block-design comparison of 100, 300, 600, and 800 mg/day carprofen given b."9.06Serum concentration and dose-response relationships for carprofen in rheumatoid arthritis. ( Caldwell, JR; Dromgoole, S; Enthoven, D; Furst, DE; Klugman, MP; Rittweger, K; Sarkissian, E; Scheer, R, 1988)
"Concentrations of carprofen in the serum and the synovial fluid were determined in 13 patients with classical or confirmed rheumatoid arthritis."7.66Concentration of carprofen in the serum and the synovial fluid in rheumatoid arthritis patients. ( Heizmann, P; Jalava, S; Kylmämaa, T, 1983)
"Thirty-eight patients with active, definite, or classical rheumatoid arthritis were tested in a double-blind, 3-week-per-arm, multiple-crossover, randomized, block-design comparison of 100, 300, 600, and 800 mg/day carprofen given b."5.06Serum concentration and dose-response relationships for carprofen in rheumatoid arthritis. ( Caldwell, JR; Dromgoole, S; Enthoven, D; Furst, DE; Klugman, MP; Rittweger, K; Sarkissian, E; Scheer, R, 1988)
"Concentrations of carprofen in the serum and the synovial fluid were determined in 13 patients with classical or confirmed rheumatoid arthritis."3.66Concentration of carprofen in the serum and the synovial fluid in rheumatoid arthritis patients. ( Heizmann, P; Jalava, S; Kylmämaa, T, 1983)
"Prednisone-treated dogs were more likely to develop polyuria, polydipsia, and polyphagia than were cyclosporine-treated dogs."2.82Comparison of the efficacy of prednisone and cyclosporine for treatment of dogs with primary immune-mediated polyarthritis. ( Herrera, MA; Kass, PH; Rhoades, AC; Sykes, JE; Vernau, W, 2016)
" For most of the efficacy variables studied, the carprofen high dosage regimen at weeks 5 and 6 was shown statistically superior or at least not different from the indomethacin group; both of these were superior to the carprofen low dosage regimen."2.65Comparative evaluation of carprofen and indomethacin in rheumatoid patients. ( Caron, M; Lussier, A; Rouleau, L; Tétreault, L, 1980)

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-199014 (93.33)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (6.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Rhoades, AC1
Vernau, W1
Kass, PH1
Herrera, MA1
Sykes, JE1
Ceuppens, JL2
Rodriguez, MA1
Goodwin, JS3
Jalava, S2
Hoting, E1
Schulz, KH1
Heizmann, P1
Kylmämaa, T1
Kaufmann, S1
Isomäki, H2
Martio, J1
Kaarela, K1
Kajander, A1
Koota, K1
Lehtinen, K1
Luukkainen, R1
Martio, T1
Nissilä, M2
Nuotio, P2
Schlumpf, U1
Standel, W1
Lussier, A1
Rouleau, L1
Caron, M1
Tétreault, L1
Furst, DE1
Caldwell, JR1
Klugman, MP1
Enthoven, D1
Rittweger, K1
Scheer, R1
Sarkissian, E1
Dromgoole, S1
Seppälä, E1
Nykänen, E1
Laitinen, O1
Vapaatalo, H1

Reviews

3 reviews available for carprofen and Rheumatoid Arthritis

ArticleYear
Effect of nonsteroidal antiinflammatory drugs on immune function.
    Seminars in arthritis and rheumatism, 1983, Volume: 13, Issue:1 Suppl 1

    Topics: Adult; Aged; Animals; Anti-Inflammatory Agents; Antibody Formation; Arthritis, Rheumatoid; Carbazole

1983
Mechanism of action of nonsteroidal anti-inflammatory agents.
    The American journal of medicine, 1984, Jul-13, Volume: 77, Issue:1A

    Topics: Animals; Anti-Inflammatory Agents; Arachidonic Acid; Arachidonic Acids; Arthritis, Rheumatoid; Carba

1984
[The introduction of non-steroidal antirheumatics: is there a rational therapy].
    Schweizerische medizinische Wochenschrift, 1982, Aug-28, Volume: 112, Issue:35

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Carbazoles; Chronic Disease; Diclofe

1982

Trials

6 trials available for carprofen and Rheumatoid Arthritis

ArticleYear
Comparison of the efficacy of prednisone and cyclosporine for treatment of dogs with primary immune-mediated polyarthritis.
    Journal of the American Veterinary Medical Association, 2016, Feb-15, Volume: 248, Issue:4

    Topics: Administration, Oral; Analgesics, Opioid; Animals; Anti-Inflammatory Agents; Anti-Inflammatory Agent

2016
A double blind crossover study of carprofen and indomethacin in patients with rheumatoid arthritis.
    Scandinavian journal of rheumatology. Supplement, 1983, Volume: 48

    Topics: Adult; Arthritis, Rheumatoid; Carbazoles; Clinical Trials as Topic; Double-Blind Method; Female; Hum

1983
Comparison of the analgesic effect of ten nonsteroidal anti-inflammatory drugs.
    British journal of rheumatology, 1984, Volume: 23, Issue:1

    Topics: Adult; Aged; Analgesics; Anti-Inflammatory Agents; Apazone; Arthritis, Rheumatoid; Aspirin; Carbazol

1984
Clinical trials in rheumatoid arthritis.
    European journal of rheumatology and inflammation, 1982, Volume: 5, Issue:4

    Topics: Adult; Aged; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Carbazoles; Clinical Trials as Topic;

1982
Comparative evaluation of carprofen and indomethacin in rheumatoid patients.
    International journal of clinical pharmacology, therapy, and toxicology, 1980, Volume: 18, Issue:11

    Topics: Anti-Arrhythmia Agents; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Carbazoles; Clinical Trials

1980
Serum concentration and dose-response relationships for carprofen in rheumatoid arthritis.
    Clinical pharmacology and therapeutics, 1988, Volume: 44, Issue:2

    Topics: Adult; Aged; Analysis of Variance; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; C

1988

Other Studies

6 other studies available for carprofen and Rheumatoid Arthritis

ArticleYear
Non-steroidal anti-inflammatory agent inhibit the synthesis of IgM rheumatoid factor in vitro.
    Lancet (London, England), 1982, Mar-06, Volume: 1, Issue:8271

    Topics: Adult; Aged; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Carbazoles; Cells, Cultured; Depressio

1982
[Photoallergic reaction to carprofen].
    Dermatosen in Beruf und Umwelt. Occupation and environment, 1984, Volume: 32, Issue:6

    Topics: Aged; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Carbazoles; Drug Hypersensitivity; Female; Hu

1984
Concentration of carprofen in the serum and the synovial fluid in rheumatoid arthritis patients.
    Scandinavian journal of rheumatology. Supplement, 1983, Volume: 48

    Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Carbazoles; Humans; Synovial Fluid

1983
[Clinical experiences with the antirheumatism agent carprofen].
    Die Medizinische Welt, 1983, Dec-02, Volume: 34, Issue:48

    Topics: Arthritis, Rheumatoid; Carbazoles; Female; Humans; Male; Middle Aged; Osteoarthritis; Spondylitis, A

1983
Special symposium on mechanisms in rheumatoid inflammation.
    European journal of rheumatology and inflammation, 1982, Volume: 5, Issue:4

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Carbazoles; Humans; Inflammation

1982
Comparison of the effects of different anti-inflammatory drugs on synovial fluid prostanoid concentrations in patients with rheumatoid arthritis.
    Clinical rheumatology, 1985, Volume: 4, Issue:3

    Topics: 6-Ketoprostaglandin F1 alpha; Acetaminophen; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Aspiri

1985