rhenium(v)dimercaptosuccinic acid profile

rhenium(V)dimercaptosuccinic acid: a possible tumor radiotherapy agent; RN given is for unlabeled cpd; a beta-emitting radiopharmaceutical [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

ID Source	ID
PubMed CID	19690448
SCHEMBL ID	8721139
MeSH ID	M0189909

Synonym
rhenium(v)dimercaptosuccinic acid
133466-85-0
SCHEMBL8721139
2,2-bis(sulfanyl)butanedioic acid;rhenium
DTXSID90928123
2,2-bis(sulfanyl)butanedioic acid--rhenium (1/1)

Timeframe	Studies, This Drug (%)	All Drugs %
pre-1990	0 (0.00)	18.7374
1990's	6 (54.55)	18.2507
2000's	4 (36.36)	29.6817
2010's	1 (9.09)	24.3611
2020's	0 (0.00)	2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Publication Type	This drug (%)	All Drugs (%)
Trials	0 (0.00%)	5.53%
Reviews	1 (9.09%)	6.00%
Case Studies	1 (9.09%)	4.05%
Observational	0 (0.00%)	0.25%
Other	9 (81.82%)	84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Substance	Relationship Strength	Studies	Classes	Roles
lactic acid Lactic Acid: A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed). 2-hydroxypropanoic acid : A 2-hydroxy monocarboxylic acid that is propanoic acid in which one of the alpha-hydrogens is replaced by a hydroxy group.	2.02	1	2-hydroxy monocarboxylic acid	algal metabolite; Daphnia magna metabolite
rhenium Rhenium: A metal, atomic number 75, atomic weight 186.207, symbol Re.	4.8	10	manganese group element atom
perrhenate perrhenate: RN given refers to cpd with MF of O4-Re	2	1	monovalent inorganic anion; rhenium oxoanion
succimer Succimer: A mercaptodicarboxylic acid used as an antidote to heavy metal poisoning because it forms strong chelates with them.. succimer : A sulfur-containing carboxylic acid that is succinic acid bearing two mercapto substituents at positions 2 and 3. A lead chelator used as an antedote to lead poisoning.	4.89	11	dicarboxylic acid; dithiol; sulfur-containing carboxylic acid	chelator
tin [no description available]	1.99	1	carbon group element atom; elemental tin; metal atom	micronutrient
technetium tc 99m dimercaptosuccinic acid Technetium Tc 99m Dimercaptosuccinic Acid: A nontoxic radiopharmaceutical that is used in the diagnostic imaging of the renal cortex.	2.41	2

Condition	Relationship Strength	Studies
Rheumatoid Arthritis [description not available]	2.99	1
Bone Cancer [description not available]	3.34	2
Coronary Heart Disease [description not available]	2.99	1
Hepatocellular Carcinoma [description not available]	2.99	1
Cancer of Liver [description not available]	2.99	1
Benign Neoplasms [description not available]	3.33	2
Cancer of Skin [description not available]	2.99	1
Arthritis, Rheumatoid A chronic systemic disease, primarily of the joints, marked by inflammatory changes in the synovial membranes and articular structures, widespread fibrinoid degeneration of the collagen fibers in mesenchymal tissues, and by atrophy and rarefaction of bony structures. Etiology is unknown, but autoimmune mechanisms have been implicated.	2.99	1
Bone Neoplasms Tumors or cancer located in bone tissue or specific BONES.	3.34	2
Coronary Disease An imbalance between myocardial functional requirements and the capacity of the CORONARY VESSELS to supply sufficient blood flow. It is a form of MYOCARDIAL ISCHEMIA (insufficient blood supply to the heart muscle) caused by a decreased capacity of the coronary vessels.	2.99	1
Carcinoma, Hepatocellular A primary malignant neoplasm of epithelial liver cells. It ranges from a well-differentiated tumor with EPITHELIAL CELLS indistinguishable from normal HEPATOCYTES to a poorly differentiated neoplasm. The cells may be uniform or markedly pleomorphic, or form GIANT CELLS. Several classification schemes have been suggested.	2.99	1
Liver Neoplasms Tumors or cancer of the LIVER.	2.99	1
Neoplasms New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.	3.33	2
Skin Neoplasms Tumors or cancer of the SKIN.	2.99	1
Musculoskeletal Pain Discomfort stemming from muscles, LIGAMENTS, tendons, and bones.	2.99	1
Pheochromocytoma, Extra-Adrenal [description not available]	2.03	1
Pheochromocytoma A usually benign, well-encapsulated, lobular, vascular tumor of chromaffin tissue of the ADRENAL MEDULLA or sympathetic paraganglia. The cardinal symptom, reflecting the increased secretion of EPINEPHRINE and NOREPINEPHRINE, is HYPERTENSION, which may be persistent or intermittent. During severe attacks, there may be HEADACHE; SWEATING, palpitation, apprehension, TREMOR; PALLOR or FLUSHING of the face, NAUSEA and VOMITING, pain in the CHEST and ABDOMEN, and paresthesias of the extremities. The incidence of malignancy is as low as 5% but the pathologic distinction between benign and malignant pheochromocytomas is not clear. (Dorland, 27th ed; DeVita Jr et al., Cancer: Principles & Practice of Oncology, 3d ed, p1298)	2.03	1
Aging The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.	1.99	1
Cancer of Lung [description not available]	1.99	1
Cancer of Prostate [description not available]	1.99	1
Lung Neoplasms Tumors or cancer of the LUNG.	1.99	1
Prostatic Neoplasms Tumors or cancer of the PROSTATE.	1.99	1
Carcinoma, Ehrlich Tumor A transplantable, poorly differentiated malignant tumor which appeared originally as a spontaneous breast carcinoma in a mouse. It grows in both solid and ascitic forms.	2	1
Cancer of Cervix [description not available]	2	1
Uterine Cervical Neoplasms Tumors or cancer of the UTERINE CERVIX.	2	1

rhenium(v)dimercaptosuccinic acid

Description

Cross-References

Synonyms (6)

Research

Studies (11)

Market Indicators

Research Demand Index: 11.71

Study Types