Page last updated: 2024-10-20

pyridoxal phosphate and Rheumatoid Arthritis

pyridoxal phosphate has been researched along with Rheumatoid Arthritis in 11 studies

Pyridoxal Phosphate: This is the active form of VITAMIN B 6 serving as a coenzyme for synthesis of amino acids, neurotransmitters (serotonin, norepinephrine), sphingolipids, aminolevulinic acid. During transamination of amino acids, pyridoxal phosphate is transiently converted into pyridoxamine phosphate (PYRIDOXAMINE).
pyridoxal 5'-phosphate : The monophosphate ester obtained by condensation of phosphoric acid with the primary hydroxy group of pyridoxal.

Research Excerpts

ExcerptRelevanceReference
"The purpose of this study was to determine if nonsupplementing older women (aged >or=55 years) with rheumatoid arthritis had higher plasma homocysteine and lower B-vitamin status compared to healthy controls."7.74Elevated plasma homocysteine and low vitamin B-6 status in nonsupplementing older women with rheumatoid arthritis. ( Manore, MM; Woolf, K, 2008)
"The purpose of this study was to determine if nonsupplementing older women (aged >or=55 years) with rheumatoid arthritis had higher plasma homocysteine and lower B-vitamin status compared to healthy controls."3.74Elevated plasma homocysteine and low vitamin B-6 status in nonsupplementing older women with rheumatoid arthritis. ( Manore, MM; Woolf, K, 2008)
"Patients with rheumatoid arthritis were found to have low plasma pyridoxal phosphate."3.65Vitamin B6 levels in rheumatoid arthritis: effect of treatment. ( Bernhart, FW; György, P; Schumacher, HR, 1975)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19903 (27.27)18.7374
1990's1 (9.09)18.2507
2000's3 (27.27)29.6817
2010's4 (36.36)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Sande, JS1
Ulvik, A1
Midttun, Ø1
Ueland, PM1
Hammer, HB1
Valen, M1
Apalset, EM1
Gjesdal, CG1
Chang, HY1
Tang, FY1
Chen, DY1
Chih, HM1
Huang, ST1
Cheng, HD1
Lan, JL1
Chiang, EP2
Huang, SC2
Wei, JC2
Wu, DJ2
Huang, YC2
Lin, PT1
Bekpinar, S1
Koçak, H1
Unlüçerçi, Y1
Genç, S1
Akdağ-Köse, A1
Göğüş, F1
Bagley, PJ1
Roubenoff, R2
Nadeau, M1
Selhub, J2
Woolf, K1
Manore, MM1
Roubenoff, RA1
Nadeau, MR1
Cannon, JG1
Freeman, LM1
Dinarello, CA1
Rosenberg, IH1
Schumacher, HR1
Bernhart, FW1
György, P1
Bruckner, FE1
Smith, HG1
Lakatos, C1
Chamberlain, MA1
Anderson, BB1
Peart, MB1
Fulford-Jones, CE1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
[NCT00944866]30 participants (Anticipated)Observational2008-03-31Active, not recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

3 trials available for pyridoxal phosphate and Rheumatoid Arthritis

ArticleYear
Clinical use of cyclooxygenase inhibitors impairs vitamin B-6 metabolism.
    The American journal of clinical nutrition, 2013, Volume: 98, Issue:6

    Topics: Animals; Arthritis, Rheumatoid; Celecoxib; Cricetinae; Cross-Sectional Studies; Cyclooxygenase Inhib

2013
Vitamin B(6) supplementation improves pro-inflammatory responses in patients with rheumatoid arthritis.
    European journal of clinical nutrition, 2010, Volume: 64, Issue:9

    Topics: Arthritis, Rheumatoid; B-Lymphocytes; Biomarkers; C-Reactive Protein; Cytokines; Dietary Supplements

2010
The evaluation of C-reactive protein, homocysteine and vitamin B6 concentrations in Behçet and rheumatoid arthritis disease.
    Clinica chimica acta; international journal of clinical chemistry, 2003, Volume: 329, Issue:1-2

    Topics: Adult; Arthritis, Rheumatoid; Behcet Syndrome; C-Reactive Protein; Female; Homocysteine; Humans; Mal

2003

Other Studies

8 other studies available for pyridoxal phosphate and Rheumatoid Arthritis

ArticleYear
Vitamin B-6 Status Correlates with Disease Activity in Rheumatoid Arthritis Patients During Treatment with TNFα Inhibitors.
    The Journal of nutrition, 2019, 05-01, Volume: 149, Issue:5

    Topics: Adult; Arthritis, Rheumatoid; Biomarkers; C-Reactive Protein; Female; Humans; Kynurenine; Longitudin

2019
Plasma pyridoxal 5'-phosphate is not associated with inflammatory and immune responses after adjusting for serum albumin in patients with rheumatoid arthritis: a preliminary study.
    Annals of nutrition & metabolism, 2012, Volume: 60, Issue:2

    Topics: Algorithms; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthralgia; Arthritis, Rh

2012
Plasma pyridoxal 5'-phosphate concentration is correlated with functional vitamin B-6 indices in patients with rheumatoid arthritis and marginal vitamin B-6 status.
    The Journal of nutrition, 2003, Volume: 133, Issue:4

    Topics: Adult; Arthritis, Rheumatoid; Aspartate Aminotransferases; Case-Control Studies; Cross-Sectional Stu

2003
Elevated plasma homocysteine and low vitamin B-6 status in nonsupplementing older women with rheumatoid arthritis.
    Journal of the American Dietetic Association, 2008, Volume: 108, Issue:3

    Topics: Aged; Arthritis, Rheumatoid; C-Reactive Protein; Cardiovascular Diseases; Case-Control Studies; Cros

2008
Abnormal vitamin B6 status in rheumatoid cachexia. Association with spontaneous tumor necrosis factor alpha production and markers of inflammation.
    Arthritis and rheumatism, 1995, Volume: 38, Issue:1

    Topics: Adult; Aged; Arthritis, Rheumatoid; Cachexia; Cross-Sectional Studies; Diet; Endotoxins; Female; Fol

1995
Vitamin B6 levels in rheumatoid arthritis: effect of treatment.
    The American journal of clinical nutrition, 1975, Volume: 28, Issue:11

    Topics: Adult; Aged; Arthritis, Rheumatoid; Blood Sedimentation; Dose-Response Relationship, Drug; Female; H

1975
Tryptophan metabolism in rheumatoid neuropathies.
    Annals of the rheumatic diseases, 1972, Volume: 31, Issue:4

    Topics: Adolescent; Adrenal Cortex Hormones; Adult; Aged; Arthritis, Rheumatoid; Aspirin; Child; Child, Pres

1972
The measurement of serum pyridoxal by a microbiological assay using Lactobacillus casei.
    Journal of clinical pathology, 1970, Volume: 23, Issue:3

    Topics: Adolescent; Adult; Age Factors; Aged; Anemia, Sideroblastic; Arthritis, Rheumatoid; Biological Assay

1970