riligustilide: isolated from Angelica sinensis; structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
| Flora | Rank | Flora Definition | Family | Family Definition |
|---|---|---|---|---|
| Angelica | genus | A plant genus of the family Apiaceae.[MeSH] | Apiaceae | A large plant family in the order Apiales, also known as Umbelliferae. Most are aromatic herbs with alternate, feather-divided leaves that are sheathed at the base. The flowers often form a conspicuous flat-topped umbel. Each small individual flower is usually bisexual, with five sepals, five petals, and an enlarged disk at the base of the style. The fruits are ridged and are composed of two parts that split open at maturity.[MeSH] |
| ID Source | ID |
|---|---|
| PubMed CID | 6442656 |
| CHEMBL ID | 2047346 |
| SCHEMBL ID | 6110806 |
| MeSH ID | M0507698 |
| Synonym |
|---|
| 89354-45-0 |
| 6gb38t262b , |
| unii-6gb38t262b |
| z-6.8',7.3'-diligustilide |
| riligustilide |
| (3s,3'z,5'ar,6's,7'as)-3'-butylidene-6'-propylspiro[4,5-dihydro-2-benzofuran-3,7'-5,5a,6,7a-tetrahydro-4h-cyclobuta[g][2]benzofuran]-1,1'-dione |
| CHEMBL2047346 |
| SCHEMBL6110806 |
| FS-8523 |
| DTXSID101337087 |
| (3z,3z)-6,8:7,3-diligustilide |
| spiro(cyclobut(e)isobenzofuran-7(1h),1(3h)-isobenzofuran)-1,3-dione, 3-butylidene-3,4,5,5a,6,6,7,7a-octahydro-6-propyl-, (3z,5a.alpha.,6.beta.,7.beta.,7a.alpha.)-(-)- |
| spiro(cyclobut(e)isobenzofuran-7(1h),1(3h)-isobenzofuran)-1,3-dione, 3-butylidene-3,4,5,5a,6,6,7,7a-octahydro-6-propyl-, (1r,3z,5as,6r,7ar)-rel-(-)- |
| (3z,3z)-6.8,7.3-diligustilide |
| rel-(-)-(1s,3z,5ar,6s,7as)-3-butylidene-3,4,5,5a,6,6,7,7a-octahydro-6-propylspiro(cyclobut(e)isobenzofuran-7(1h),1(3h)-isobenzofuran)-1,3-dione |
| spiro(cyclobut(e)isobenzofuran-7(1h),1(3h)-isobenzofuran)-1,3-dione, 3-butylidene-3,4,5,5a,6,6,7,7a-octahydro-6-propyl-, (1s,3z,5ar,6s,7as)-rel-(-)- |
| z-6,8,7,3-diligustilide |
| (-)-riligustilide |
| AKOS040762951 |
| Assay ID | Title | Year | Journal | Article |
|---|---|---|---|---|
| AID671223 | Cytotoxicity against human K562 cells assessed as growth inhibition after 48 hrs by SRB assay | 2012 | Journal of natural products, May-25, Volume: 75, Issue:5 | Enantiomeric derivatives of tokinolide B: absolute configuration and biological properties. |
| AID671225 | Cytotoxicity against human SKLU1 cells assessed as growth inhibition after 48 hrs by SRB assay | 2012 | Journal of natural products, May-25, Volume: 75, Issue:5 | Enantiomeric derivatives of tokinolide B: absolute configuration and biological properties. |
| AID671224 | Cytotoxicity against human HCT15 cells assessed as growth inhibition after 48 hrs by SRB assay | 2012 | Journal of natural products, May-25, Volume: 75, Issue:5 | Enantiomeric derivatives of tokinolide B: absolute configuration and biological properties. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||||
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 6 (75.00) | 24.3611 |
| 2020's | 2 (25.00) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.
| This Compound (12.25) All Compounds (24.57) |
| Publication Type | This drug (%) | All Drugs (%) |
|---|---|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 1 (11.11%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 8 (88.89%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||