Compounds > technetium tc 99m n-(methylamino)methylene diphosphonate
Page last updated: 2024-12-08

technetium tc 99m n-(methylamino)methylene diphosphonate

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

technetium Tc 99m N-(methylamino)methylene diphosphonate: structure given in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID163112
MeSH IDM0118494

Synonyms (7)

Synonym
MOLI000614
technetium tc 99m n-(methylamino)methylene diphosphonate
66225-82-9
tc-99m-nmmdp
phosphonic acid, ((methylamino)methylene)bis-, technetium-99tc salt
technetium n-(methylamino)methylene diphosphonate
[methylamino(phosphono)methyl]phosphonic acid;technetium-99
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (13)

TimeframeStudies, This Drug (%)All Drugs %
pre-19906 (46.15)18.7374
1990's7 (53.85)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 11.84

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index11.84 (24.57)
Research Supply Index2.64 (2.92)
Research Growth Index4.48 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (11.84)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews1 (7.69%)6.00%
Case Studies2 (15.38%)4.05%
Observational0 (0.00%)0.25%
Other10 (76.92%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
etidronate
Etidronic Acid: A diphosphonate which affects calcium metabolism. It inhibits ectopic calcification and slows down bone resorption and bone turnover.. etidronic acid : A 1,1-bis(phosphonic acid) that is (ethane-1,1-diyl)bis(phosphonic acid) having a hydroxy substituent at the 1-position. It inhibits the formation, growth, and dissolution of hydroxyapatite crystals by chemisorption to calcium phosphate surfaces.		1.96101,1-bis(phosphonic acid)antineoplastic agent;
bone density conservation agent;
chelator
technetium
Technetium: The first artificially produced element and a radioactive fission product of URANIUM. Technetium has the atomic symbol Tc, and atomic number 43. All technetium isotopes are radioactive. Technetium 99m (m=metastable) which is the decay product of Molybdenum 99, has a half-life of about 6 hours and is used diagnostically as a radioactive imaging agent. Technetium 99 which is a decay product of technetium 99m, has a half-life of 210,000 years.		1.9610manganese group element atom
hydroxymethanediphosphonic acid
hydroxymethanediphosphonic acid: RN given refers to parent cpd		1.96101,1-bis(phosphonic acid)
technetium tc 99m etidronate
[no description available]		1.9610
pyrophosphate
Diphosphates: Inorganic salts of phosphoric acid that contain two phosphate groups.		1.9610diphosphate ion
indium
Indium: A metallic element, atomic number 49, atomic weight 114.818, symbol In. It is named from its blue line in the spectrum.. indium atom : A metallic element first identified and named from the brilliant indigo (Latin indicum) blue line in its flame spectrum.		3.0610boron group element atom
strontium radioisotopes
Strontium Radioisotopes: Unstable isotopes of strontium that decay or disintegrate spontaneously emitting radiation. Sr 80-83, 85, and 89-95 are radioactive strontium isotopes.		1.9610
technetium tc 99m medronate
Technetium Tc 99m Medronate: A gamma-emitting radionuclide imaging agent used primarily in skeletal scintigraphy. Because of its absorption by a variety of tumors, it is useful for the detection of neoplasms.		5.02130
ConditionIndicatedRelationship StrengthStudiesTrials
Urinary Calculi
Low-density crystals or stones in any part of the URINARY TRACT. Their chemical compositions often include CALCIUM OXALATE, magnesium ammonium phosphate (struvite), CYSTINE, or URIC ACID.		01.9810
Bone Cancer
[description not available]		02.3820
Bone Neoplasms
Tumors or cancer located in bone tissue or specific BONES.		02.3820
Aseptic Necrosis of Bone
[description not available]		02.3920
Prosthesis Durability
[description not available]		01.9910
Osteonecrosis
Death of a bone or part of a bone, either atraumatic or posttraumatic.		02.3920
Cancer of Colon
[description not available]		01.9810
Cancer of Rectum
[description not available]		01.9810
Local Neoplasm Recurrence
[description not available]		01.9810
Colonic Neoplasms
Tumors or cancer of the COLON.		01.9810
Rectal Neoplasms
Tumors or cancer of the RECTUM.		01.9810
Arteriosclerosis, Coronary
[description not available]		01.9810
Coronary Artery Disease
Pathological processes of CORONARY ARTERIES that may derive from a congenital abnormality, atherosclerotic, or non-atherosclerotic cause.		01.9810
Disease Models, Animal
Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases.		01.9710
Coxa Plana
[description not available]		01.9710
Canine Diseases
[description not available]		01.9710
Cancer of Lung
[description not available]		01.9710
Lymph Node Metastasis
[description not available]		01.9710
Osteogenic Sarcoma
[description not available]		01.9710
Chondrosarcoma
A slowly growing malignant neoplasm derived from cartilage cells, occurring most frequently in pelvic bones or near the ends of long bones, in middle-aged and old people. Most chondrosarcomas arise de novo, but some may develop in a preexisting benign cartilaginous lesion or in patients with ENCHONDROMATOSIS. (Stedman, 25th ed)		01.9710
Fibrosarcoma
A sarcoma derived from deep fibrous tissue, characterized by bundles of immature proliferating fibroblasts with variable collagen formation, which tends to invade locally and metastasize by the bloodstream. (Stedman, 25th ed)		01.9710
Lung Neoplasms
Tumors or cancer of the LUNG.		01.9710
Osteosarcoma
A sarcoma originating in bone-forming cells, affecting the ends of long bones. It is the most common and most malignant of sarcomas of the bones, and occurs chiefly among 10- to 25-year-old youths. (From Stedman, 25th ed)		01.9710
Rheumatoid Arthritis
[description not available]		01.9710
Plica Syndrome
[description not available]		01.9710
Arthritis, Rheumatoid
A chronic systemic disease, primarily of the joints, marked by inflammatory changes in the synovial membranes and articular structures, widespread fibrinoid degeneration of the collagen fibers in mesenchymal tissues, and by atrophy and rarefaction of bony structures. Etiology is unknown, but autoimmune mechanisms have been implicated.		01.9710
Synovitis
Inflammation of the SYNOVIAL MEMBRANE.		01.9710
Asymmetric Diabetic Proximal Motor Neuropathy
[description not available]		02.8810
Arthropathies
[description not available]		02.8810
Diabetic Neuropathies
Peripheral, autonomic, and cranial nerve disorders that are associated with DIABETES MELLITUS. These conditions usually result from diabetic microvascular injury involving small blood vessels that supply nerves (VASA NERVORUM). Relatively common conditions which may be associated with diabetic neuropathy include third nerve palsy (see OCULOMOTOR NERVE DISEASES); MONONEUROPATHY; mononeuropathy multiplex; diabetic amyotrophy; a painful POLYNEUROPATHY; autonomic neuropathy; and thoracoabdominal neuropathy. (From Adams et al., Principles of Neurology, 6th ed, p1325)		02.8810
Joint Diseases
Diseases involving the JOINTS.		02.8810
Osteomyelitis
INFLAMMATION of the bone as a result of infection. It may be caused by a variety of infectious agents, especially pyogenic (PUS - producing) BACTERIA.		02.8810
Femur Neck Fractures
[description not available]		01.9710
Fractures, Ununited
A fracture in which union fails to occur, the ends of the bone becoming rounded and eburnated, and a false joint occurs. (Stedman, 25th ed)		01.9710
Femoral Neck Fractures
Fractures of the short, constricted portion of the thigh bone between the femur head and the trochanters. It excludes intertrochanteric fractures which are HIP FRACTURES.		01.9710