cimetidine has been researched along with Rheumatoid Arthritis in 17 studies
Cimetidine: A histamine congener, it competitively inhibits HISTAMINE binding to HISTAMINE H2 RECEPTORS. Cimetidine has a range of pharmacological actions. It inhibits GASTRIC ACID secretion, as well as PEPSIN and GASTRIN output.
cimetidine : A member of the class of guanidines that consists of guanidine carrying a methyl substituent at position 1, a cyano group at position 2 and a 2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl group at position 3. It is a H2-receptor antagonist that inhibits the production of acid in stomach.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Eighty-six rheumatoid arthritis (RA) patients affected by endoscopically proven DU (n = 44) or GU (n = 42), and on chronic NSAID therapy which was not suspended during anti-ulcer therapy, were randomized to cimetidine (400 mg t." | 9.08 | Peptic ulcer therapy with cimetidine versus tripotassium dicitrato bismuthate in rheumatoid arthritis patients undergoing chronic NSAID treatment. ( Ardizzone, S; Bianchi Porro, G; Caruso, I; Lazzaroni, M; Manzionna, G; Montrone, F; Petrillo, M, 1998) |
| "110 patients with benign gastric ulcer and concomitant joint diseases (rheumatoid arthritis, osteoarthrosis) were treated in a comparative short-term clinical trial to assess the relative efficacy of calcitonin (daily 100 MRC of salmon calcitonin intramuscularly), cimetidine (daily 1000 mg orally) and colloidal bismuth subcitrate (De-Nol-four times a day in doses of 5 ml diluted with 15 ml of water)." | 9.06 | Calcitonin versus cimetidine or De-Nol in gastric ulcer treatment. An endoscopically controlled trial. ( Badurski, J; Janke, A; Namiot, Z; Sajewicz, I; Stasiewicz, J, 1988) |
| "The interaction between sulphasalazine and cimetidine has been studied, a drug combination which is quite likely in view of the higher incidence of peptic ulceration in patients with RA." | 7.68 | Lack of interaction between sulphasalazine and cimetidine in patients with rheumatoid arthritis. ( Breckenridge, AM; Bucknall, RC; Coleman, MD; Galvani, D; Park, BK; Pirmohamed, M, 1993) |
| "Eighty-six rheumatoid arthritis (RA) patients affected by endoscopically proven DU (n = 44) or GU (n = 42), and on chronic NSAID therapy which was not suspended during anti-ulcer therapy, were randomized to cimetidine (400 mg t." | 5.08 | Peptic ulcer therapy with cimetidine versus tripotassium dicitrato bismuthate in rheumatoid arthritis patients undergoing chronic NSAID treatment. ( Ardizzone, S; Bianchi Porro, G; Caruso, I; Lazzaroni, M; Manzionna, G; Montrone, F; Petrillo, M, 1998) |
| "110 patients with benign gastric ulcer and concomitant joint diseases (rheumatoid arthritis, osteoarthrosis) were treated in a comparative short-term clinical trial to assess the relative efficacy of calcitonin (daily 100 MRC of salmon calcitonin intramuscularly), cimetidine (daily 1000 mg orally) and colloidal bismuth subcitrate (De-Nol-four times a day in doses of 5 ml diluted with 15 ml of water)." | 5.06 | Calcitonin versus cimetidine or De-Nol in gastric ulcer treatment. An endoscopically controlled trial. ( Badurski, J; Janke, A; Namiot, Z; Sajewicz, I; Stasiewicz, J, 1988) |
| "Agranulocytosis and septicaemia developing in a patient with rheumatoid arthritis after 3 years' intermittent treatment with diclofenac, cimetidine and flucloxacillin for staphylococcal osteomyelitis is described." | 3.69 | Agranulocytosis in rheumatoid arthritis associated with long-term flucloxacillin for staphylococcal osteomyelitis. ( Burton, IE; Moussa, KM; Sanders, PA, 1995) |
| "The interaction between sulphasalazine and cimetidine has been studied, a drug combination which is quite likely in view of the higher incidence of peptic ulceration in patients with RA." | 3.68 | Lack of interaction between sulphasalazine and cimetidine in patients with rheumatoid arthritis. ( Breckenridge, AM; Bucknall, RC; Coleman, MD; Galvani, D; Park, BK; Pirmohamed, M, 1993) |
| "A 41-year-old man with rheumatoid arthritis developed severe acute hepatitis 3 days after starting cimetidine for duodenal ulcer." | 3.68 | [Cimetidine hepatitis]. ( Cohen, N; Golik, A; Zaidenstein, R, 1992) |
| "In a pilot study, 26 rheumatoid arthritic patients taking continuous, stable dosage regimens of nonsteroidal anti-inflammatory drugs and with developed gastric and duodenal lesions were administered sucralfate 1 g four times per day (14 patients) or cimetidine 400 mg twice daily (12 patients) in a single-blind regimen for six weeks." | 2.66 | Effect of sucralfate and cimetidine on rheumatoid patients with active gastroduodenal lesions who are taking nonsteroidal anti-inflammatory drugs. A pilot study. ( Cox, N; Fine, D; Hillier, K; Jewell, R; Shepherd, HA, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (64.71) | 18.7374 |
| 1990's | 5 (29.41) | 18.2507 |
| 2000's | 1 (5.88) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kimberly, RP | 1 |
| Weinberg, H | 1 |
| Rudd, E | 1 |
| Permin, H | 2 |
| Norn, S | 2 |
| Skov, PS | 2 |
| Geisler, A | 1 |
| Klysner, R | 1 |
| Andersen, V | 1 |
| Wiik, A | 1 |
| Manthorpe, R | 1 |
| Nielsen, H | 1 |
| Petersen, J | 1 |
| Mitchell, WS | 1 |
| Sturrock, RD | 1 |
| Gow, PJ | 1 |
| Stewart, JT | 1 |
| O'Laughlin, JC | 1 |
| Silvoso, GR | 1 |
| Ivey, KJ | 1 |
| Pirmohamed, M | 1 |
| Coleman, MD | 1 |
| Galvani, D | 1 |
| Bucknall, RC | 1 |
| Breckenridge, AM | 1 |
| Park, BK | 1 |
| Burton, IE | 1 |
| Moussa, KM | 1 |
| Sanders, PA | 1 |
| Bianchi Porro, G | 1 |
| Lazzaroni, M | 1 |
| Petrillo, M | 1 |
| Ardizzone, S | 1 |
| Manzionna, G | 1 |
| Caruso, I | 1 |
| Montrone, F | 1 |
| Stanislavchuk, MA | 1 |
| Sugiyama, T | 1 |
| Tanaka, H | 1 |
| Kawai, S | 1 |
| Zaidenstein, R | 1 |
| Cohen, N | 1 |
| Golik, A | 1 |
| Shepherd, HA | 1 |
| Fine, D | 1 |
| Hillier, K | 1 |
| Jewell, R | 1 |
| Cox, N | 1 |
| Janke, A | 1 |
| Badurski, J | 1 |
| Stasiewicz, J | 1 |
| Sajewicz, I | 1 |
| Namiot, Z | 1 |
| Roth, SH | 1 |
| Bennett, RE | 1 |
| Mitchell, CS | 1 |
| Hartman, RJ | 1 |
| Dijkmans, BA | 1 |
| van der Voet, GB | 1 |
| Cats, A | 1 |
| de Wolff, FA | 1 |
| Meretey, K | 1 |
| Bohm, U | 1 |
| Falus, A | 1 |
6 trials available for cimetidine and Rheumatoid Arthritis
| Article | Year |
|---|---|
Peptic ulcer therapy with cimetidine versus tripotassium dicitrato bismuthate in rheumatoid arthritis patients undergoing chronic NSAID treatment.
Topics: Administration, Oral; Adult; Anti-Inflammatory Agents, Non-Steroidal; Anti-Ulcer Agents; Arthritis, | 1998 |
[The effect of combined therapy on the ortofen concentration of the blood plasma and synovial fluid in patients with rheumatoid arthritis].
Topics: Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Cimetidine | 1999 |
Improvement of periarticular osteoporosis in postmenopausal women with rheumatoid arthritis by beta-alanyl-L-histidinato zinc: a pilot study.
Topics: Alkaline Phosphatase; Anti-Ulcer Agents; Arthritis, Rheumatoid; Bone and Bones; Bone Density; Carnos | 2000 |
Effect of sucralfate and cimetidine on rheumatoid patients with active gastroduodenal lesions who are taking nonsteroidal anti-inflammatory drugs. A pilot study.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Cimetidine; Duodenum; Female; | 1989 |
Calcitonin versus cimetidine or De-Nol in gastric ulcer treatment. An endoscopically controlled trial.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Anti-Ulcer Agents; Arthritis, Rheumatoid; Calc | 1988 |
Cimetidine therapy in nonsteroidal anti-inflammatory drug gastropathy. Double-blind long-term evaluation.
Topics: Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Cimetidine; Clinical Tri | 1987 |
11 other studies available for cimetidine and Rheumatoid Arthritis
| Article | Year |
|---|---|
Great reduction in renal function associated with cimetidine.
Topics: Arthritis, Rheumatoid; Cimetidine; Creatinine; Female; Guanidines; Histamine H2 Antagonists; Humans; | 1980 |
[H2-antihistamines (cimetidine) in allergic-inflammatory reactions].
Topics: Arthritis, Rheumatoid; Cimetidine; Guanidines; Histamine H1 Antagonists; Humans; Receptors, Histamin | 1980 |
Possible role of histamine in rheumatoid arthritis. Treatment with cimetidine and mepyramine.
Topics: Adolescent; Adult; Aminopyridines; Arthritis, Rheumatoid; Cimetidine; Drug Therapy, Combination; Fem | 1981 |
Ulcers and anti-inflammatory agents.
Topics: Adult; Aged; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Cimetidine; Duodenal Ulcer; Female; Gu | 1982 |
The arthritic ulcer: a retrospective study of peptic ulceration in patients with rheumatoid arthritis.
Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Cimetidine; Drug Therapy, Combination; Duodenal Ulc | 1982 |
Healing of aspirin-associated peptic ulcer disease despite continued salicylate ingestion.
Topics: Adolescent; Adult; Aged; Antacids; Arthritis, Rheumatoid; Aspirin; Cimetidine; Duodenal Ulcer; Femal | 1981 |
Lack of interaction between sulphasalazine and cimetidine in patients with rheumatoid arthritis.
Topics: Adult; Aged; Arthritis, Rheumatoid; Cimetidine; Dose-Response Relationship, Drug; Drug Interactions; | 1993 |
Agranulocytosis in rheumatoid arthritis associated with long-term flucloxacillin for staphylococcal osteomyelitis.
Topics: Aged; Agranulocytosis; Arthritis, Rheumatoid; Cimetidine; Female; Floxacillin; Fluorescent Antibody | 1995 |
[Cimetidine hepatitis].
Topics: Acute Disease; Adult; Arthritis, Rheumatoid; Chemical and Drug Induced Liver Injury; Cimetidine; Duo | 1992 |
Serum aluminium concentrations in patients with rheumatoid arthritis.
Topics: Aluminum; Antacids; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Cimetidine; Fema | 1987 |
Action of histamine on PHA chemiluminescence response of blood mononuclear cells in autoimmune patients.
Topics: Arthritis, Rheumatoid; Autoimmune Diseases; Cimetidine; Histamine; Humans; Luminescent Measurements; | 1986 |