Page last updated: 2024-11-02

oxaprozin and Rheumatoid Arthritis

oxaprozin has been researched along with Rheumatoid Arthritis in 12 studies

Oxaprozin: An oxazole-propionic acid derivative, cyclooxygenase inhibitor, and non-steroidal anti-inflammatory drug that is used in the treatment of pain and inflammation associated with of OSTEOARTHRITIS; RHEUMATOID ARTHRITIS; and ARTHRITIS, JUVENILE.
oxaprozin : A monocarboxylic acid that is a propionic acid derivative having a 4,5-diphenyl-1,3-oxazol-2-yl substituent at position 3. It is non-steroidal anti-inflammatory drug commonly used to relieve the pain and inflammatory responses associated with osteoarthritis and rheumatoid arthritis.

Research Excerpts

ExcerptRelevanceReference
"The efficacy and safety of leflunomide (LEF) in the treatment of rheumatoid arthritis (RA) were evaluated and the comparison with methotrexate's (MTX's) was performed in a 12-week, single-blind, randomized, parallel trial for treating 81 patients with RA."9.09A randomized, controlled, single-blind trial of leflunomide in the treatment of rheumatoid arthritis. ( Hu, Y; Liu, P; Tu, S, 2001)
"Oxaprozin, an anti-inflammatory agent with a half-life of 50 hours, was compared in regard to efficacy and tolerance with sulindac in a 12-week double-blind parallel treatment trial of rheumatoid arthritis."9.05Oxaprozin and sulindac in rheumatoid arthritis: a double-blind comparative trial. ( Fraser, KM; Hall, SM; Mackinnon, MJ; Palmer, DG; Zuccollo, R, 1983)
"We describe a case of Stevens-Johnson syndrome (SJS) associated with oxaprozin ("Daypro"), a relatively new nonsteroidal antiinflammatory drug (NSAID) of the propionic acid group."7.70A case of Stevens-Johnson syndrome associated with oxaprozin therapy. ( Bell, MJ; Bishara, LD, 1998)
"The efficacy and safety of leflunomide (LEF) in the treatment of rheumatoid arthritis (RA) were evaluated and the comparison with methotrexate's (MTX's) was performed in a 12-week, single-blind, randomized, parallel trial for treating 81 patients with RA."5.09A randomized, controlled, single-blind trial of leflunomide in the treatment of rheumatoid arthritis. ( Hu, Y; Liu, P; Tu, S, 2001)
"The incidence of potentially serious drug-related elevations of BUN or serum creatinine was examined among 1468 patients with rheumatoid arthritis or osteoarthritis who took daily therapeutic doses of aspirin, ibuprofen, or oxaprozin, an investigational nonsteroidal antiinflammatory drug (NSAID), in multicenter clinical trials."5.06Renal safety of two analgesics used over the counter: ibuprofen and aspirin. ( Bonney, SL; Hedrich, DA; Northington, RS; Walker, BR, 1986)
"Oxaprozin, an anti-inflammatory agent with a half-life of 50 hours, was compared in regard to efficacy and tolerance with sulindac in a 12-week double-blind parallel treatment trial of rheumatoid arthritis."5.05Oxaprozin and sulindac in rheumatoid arthritis: a double-blind comparative trial. ( Fraser, KM; Hall, SM; Mackinnon, MJ; Palmer, DG; Zuccollo, R, 1983)
"We describe a case of Stevens-Johnson syndrome (SJS) associated with oxaprozin ("Daypro"), a relatively new nonsteroidal antiinflammatory drug (NSAID) of the propionic acid group."3.70A case of Stevens-Johnson syndrome associated with oxaprozin therapy. ( Bell, MJ; Bishara, LD, 1998)
"Oxaprozin is a nonsteroidal anti-inflammatory drug characterised by a propionic acid-based structure."2.43A review of the emerging profile of the anti-inflammatory drug oxaprozin. ( Bertolotto, M; Dallegri, F; Ottonello, L, 2005)
"Oxaprozin is an effective, long-acting anti-inflammatory analgesic, but its comparative advantages remain undefined."2.39A review of selected newer nonsteroidal anti-inflammatory drugs. ( Amadio, P; Cummings, DM, 1994)
"Oxaprozin (Wy-21743) is a novel and unique compound among NSAIDs: it bears an aliphatic propionic acid function as a side chain in contrast to the large group of acetic acids and profens."1.28The transsynovial distribution of oxaprozin. ( Kurowski, M; Thabe, H, 1989)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19904 (33.33)18.7374
1990's5 (41.67)18.2507
2000's3 (25.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Shi, W1
Wang, YM1
Cheng, NN1
Chen, BY1
Li, D1
Dallegri, F1
Bertolotto, M1
Ottonello, L1
Zuccollo, R1
Mackinnon, MJ1
Fraser, KM1
Hall, SM1
Palmer, DG1
Schorn, D1
Cummings, DM1
Amadio, P1
Bell, MJ1
Bishara, LD1
Bellamy, N1
Campbell, J1
Syrotuik, J1
Hu, Y1
Tu, S1
Liu, P1
al-Faks, MA1
Pugh, MC1
Kurowski, M1
Thabe, H1
Bonney, SL1
Northington, RS1
Hedrich, DA1
Walker, BR1

Reviews

4 reviews available for oxaprozin and Rheumatoid Arthritis

ArticleYear
[Meta-analysis on the effect and adverse reaction on patients with osteoarthritis and rheumatoid arthritis treated with non-steroidal anti-inflammatory drugs].
    Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi, 2003, Volume: 24, Issue:11

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Butanones; China; Diclofenac; Humans

2003
A review of the emerging profile of the anti-inflammatory drug oxaprozin.
    Expert opinion on pharmacotherapy, 2005, Volume: 6, Issue:5

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Drug Industry; Humans; Oxap

2005
A review of selected newer nonsteroidal anti-inflammatory drugs.
    American family physician, 1994, Volume: 49, Issue:5

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Butanones; Clinical Trials as Topic;

1994
Oxaprozin: a new NSAID.
    Orthopaedic review, 1992, Volume: 21, Issue:5

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Double-Blind Method; Half-Life; Huma

1992

Trials

4 trials available for oxaprozin and Rheumatoid Arthritis

ArticleYear
Oxaprozin and sulindac in rheumatoid arthritis: a double-blind comparative trial.
    Current medical research and opinion, 1983, Volume: 8, Issue:5

    Topics: Adult; Aged; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Clinical Trials as Topic; Double-Blind

1983
A comparison between oxaprozin and naproxen in rheumatoid arthritis.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1981, Nov-14, Volume: 60, Issue:20

    Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Clinical Trials as Topic; Double-Blind Method; Fema

1981
A randomized, controlled, single-blind trial of leflunomide in the treatment of rheumatoid arthritis.
    Journal of Tongji Medical University = Tong ji yi ke da xue xue bao, 2001, Volume: 21, Issue:1

    Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Female; Hum

2001
Renal safety of two analgesics used over the counter: ibuprofen and aspirin.
    Clinical pharmacology and therapeutics, 1986, Volume: 40, Issue:4

    Topics: Adult; Aged; Arthritis, Rheumatoid; Aspirin; Blood Urea Nitrogen; Clinical Trials as Topic; Creatini

1986

Other Studies

4 other studies available for oxaprozin and Rheumatoid Arthritis

ArticleYear
Oxaprozin for arthritis.
    The Medical letter on drugs and therapeutics, 1993, Feb-19, Volume: 35, Issue:890

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Humans; Osteoarthritis; Oxaprozin; P

1993
A case of Stevens-Johnson syndrome associated with oxaprozin therapy.
    The Journal of rheumatology, 1998, Volume: 25, Issue:10

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Female; Humans; Middle Aged; Oxaproz

1998
Comparative study of self-rating pain scales in rheumatoid arthritis patients.
    Current medical research and opinion, 1999, Volume: 15, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Eval

1999
The transsynovial distribution of oxaprozin.
    Agents and actions, 1989, Volume: 27, Issue:3-4

    Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Female; Humans; Male; M

1989