cysteine has been researched along with Rheumatoid Arthritis in 140 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 25 (17.86) | 18.7374 |
1990's | 40 (28.57) | 18.2507 |
2000's | 43 (30.71) | 29.6817 |
2010's | 28 (20.00) | 24.3611 |
2020's | 4 (2.86) | 2.80 |
Authors | Studies |
---|---|
Frank, M | 1 |
Li, CY; Li, Q; Wang, B; Yang, CM; Zhang, H; Zhang, Q | 1 |
Dulubova, I; Eken, Y; Ferguson, DA; Hotema, M; Jiang, X; Lee, CI; Liu, L; McCauley, L; Reisman, SA; Trevino, I; Visnick, M; Wigley, WC; Wilson, AK | 1 |
Bian, X; Hu, W; Liao, J; Wang, Z; Wu, J; Yu, Y; Zhu, YZ | 1 |
Ali, L; Aspberg, A; Björkman, LI; Flowers, SA; Jin, C; Kalamajski, S; Karlsson, NG; Raj, JR | 1 |
Castiglioni, L; Colazzo, F; Gelosa, P; Sironi, L; Tremoli, E | 1 |
Fonović, M; Turk, B; Vizovišek, M | 1 |
Hase, I; Ishii, Y; Kurasawa, K; Sakuma, H; Takizawa, H; Yamaguchi, B | 1 |
Fukada, A; Nozue, T; Suda, T; Toyoshima, M | 2 |
Kalemci, S; Sarıhan, A; Şimşek, A; Zeybek, A | 1 |
Mitani, Y | 1 |
Tanaka, E; Yamanaka, H | 1 |
Amano, K; Kameda, H; Kishimoto, M; Kurasawa, T; Nagasawa, H; Takeuchi, T | 1 |
Tamada, Y; Watanabe, D; Yanagishita, T | 1 |
Abe, C; Funahashi, K; Katayama, K; Kondo, M; Matsubara, T; Matsuno, H; Okada, M; Sagawa, A; Sakai, Y; Yamasaki, K | 1 |
Ito, S | 2 |
Jia, WW; Liu, L; Liu, XH; Pan, LL; Shen, XY; Wu, WJ; Yang, D; Zhang, QY; Zhu, YZ | 1 |
Arima, N; Endo, T; Ibaraki, H; Kanazawa, T; Seta, Y; Takashima, Y | 1 |
Ideguchi, H; Ishigatsubo, Y; Nagaoka, S; Ohono, S; Soga, T; Suda, A | 1 |
Hagihara, M; Hayashi, K; Miyasaka, N; Ogasawara, H; Tohda, S; Toi, H; Tojo, N | 1 |
Arimitsu, J; Hagihara, K; Hirano, T; Kawai, M; Kawase, I; Kuwahara, Y; Nakanishi, K; Narazaki, M; Ogata, A; Shima, Y; Tanaka, T; Terabe, F | 1 |
Hirohata, S; Tomita, T; Yanagida, T; Yoshikawa, H | 1 |
Yamanaka, H | 1 |
Mimori, T; Yukawa, N | 1 |
Aono, H; Kageyama, M; Ohashi, K; Oki, K; Sasano, M; Tsuji, F | 1 |
Abe, M; Kinoshita, M; Nakajima, M; Ohara, H; Ueda, N | 1 |
Iwatani, M; Kobashigawa, T; Kotake, S; Nanke, Y; Yago, T; Yamanaka, H | 1 |
Causey, CP; Cook, PF; Knuckley, B; Pellechia, PJ; Thompson, PR | 1 |
Aono, H; Katsuta, O; Okamoto, M; Setoguchi, C; Tsuji, F | 1 |
Komase, Y; Sakaida, H; Takemura, T | 1 |
Amasaki, Y; Fujisaku, A; Ichikawa, K; Mukai, M; Ohnishi, K; Ohsaki, H; Sagawa, A; Shimizu, M; Yasuda, I | 1 |
Bhabak, KP; Bhuyan, BJ; Mugesh, G | 1 |
Kawai, S; Miyasaka, N; Takeuchi, T; Tanaka, Y; Yamamoto, K | 1 |
Koyama, Y; Ohta, T; Shiraishi, H; Uchino, A | 1 |
Amano, H; Kageyama, M; Kempe, K; Kusaoi, M; Matsudaira, R; Matsushita, M; Morimoto, S; Nawata, M; Ogasawara, M; Onuma, S; Sekiya, F; Tada, K; Takasaki, Y; Tamura, N; Toyama, S; Yamaji, K | 1 |
Hirotoshi, K; Ikeda, K; Kawashima, H; Kobayashi, Y; Nakagomi, D; Nakajima, H; Suto, A | 1 |
Ichikawa, N; Yamanaka, H | 1 |
Kageyama, M; Kempe, K; Kon, T; Kusaoi, M; Matsudaira, R; Matsushita, M; Ogasawara, M; Onuma, S; Sekiya, F; Sugimoto, K; Tada, K; Takasaki, Y; Tamura, N; Yamaji, K | 1 |
Tamura, N | 1 |
Waring, RH; Wilkinson, LJ | 1 |
Kumagai, N; Ono, K; Sakai, Y; Wakamatsu, S | 1 |
FEDERICO, OM; HEIMER, R | 1 |
Frick, B; Fuchs, D; Herold, M; Kaser, S; Ledochowski, M; Mur, E; Schroecksnadel, K; Wirleitner, B | 1 |
Harada, T; Obayashi, M; Takahara, K; Uzu, T; Yamato, M; Yamauchi, A | 1 |
Urata, Y | 1 |
Hashimoto, S; Iwata, M; Nagai, C; Shimizu, Y; Takeda, T; Takeuchi, M; Uchiyama, S | 1 |
Gomita, Y; Kawasaki, Y; Moriyama, M; Shibata, K | 1 |
Kawabata, D; Mimori, T | 1 |
Aoyama, M; Asai, K; Fukuoka, M; Kobayashi, M; Kusabe, T; Otsuka, T; Tanikawa, T; Waguri-Nagaya, Y | 1 |
Asada, H; Izumi, A; Katsumi, S; Kobayashi, N; Miyagawa, S; Niizeki, H | 1 |
Amano, K; Kameda, H; Sekiguchi, N; Takeuchi, T | 1 |
Hara, S; Hoshino, J; Katori, H; Sawa, N; Suwabe, T; Tagami, T; Takaichi, K; Takemoto, F; Ubara, Y | 1 |
Hur, JW; Lee, CW; Yoo, DH | 1 |
Hokonohara, D; Kajiya, T; Kuroda, A; Tei, C | 1 |
Yamamoto, T; Yokozeki, H | 1 |
Hara, M; Inoue, E; Iwatani, M; Kamatani, N; Nakajima, A; Nakamura, T; Tomatsu, T; Yamanaka, H | 1 |
Nakamura, K; Nakashima, T; Ochi, S; Oda, H; Suematsu, A; Tajiri, Y; Taka, J; Takayanagi, H; Tanaka, S | 1 |
Itou, K; Kanazawa, T; Kuga, Y; Morishita, M; Tanida, K; Yokota, N | 1 |
Matsuda, T; Ohtsubo, H | 1 |
Abe, S; Azuma, A; Fukuda, Y; Kudoh, S; Nakayama, T; Nei, T; Saito, Y; Usuki, J | 1 |
Fukushima, K; Gono, T; Ikeda, S; Katoh, N; Matsuda, M; Mitsuhashi, S; Takei, Y | 1 |
Fujimura, M; Kasahara, K; Nakao, S; Nakatsumi, Y; Tambo, Y; Yasui, M | 1 |
Makino, F; Mochizuki, H; Morioka, T; Ogiwara, Y; Sugihara, T; Takahashi, H | 1 |
Emery, P; Huston, G; Idle, JR; Mitchell, SC; Panayi, GS; Shah, RR; Smith, RL; Waring, RH; Welsh, KI | 1 |
Johnson, S; Kaung, C; Roboz, J; Yu, TF | 1 |
Ament, HJ; Henrichs, AM; Muijsers, AO; van de Stadt, RJ; van der Korst, JK | 2 |
Butler, M; Carruthers, G; Freeman, D; Harth, M; Rothwell, R; Weir, D | 1 |
Ishizaki, C; Kohsokabe, S; Nishida, H; Sueki, H | 1 |
Brooks, P; Conaghan, PG | 1 |
Ando, J; Hiramatsu, K; Inokuma, S; Matsuzaki, Y; Miyakuni, Y; Shiratori, K | 1 |
Brooks, P; Conaghan, PG; Girgis, L | 1 |
Rafter, GW | 1 |
Hashimoto, M; Hiramatsu, K; Hosaka, M; Iwabuchi, H; Kaga, S; Kanemitsu, H; Kasama, T; Matsuda, A; Negishi, M; Yamazaki, J | 1 |
Ichibangase, Y; Ohtsuka, E; Oribe, M; Sakai, K; Shiokawa, S; Takahashi, H; Wada, T; Yamamoto, M; Yasuda, M; Yoshioka, K | 1 |
Kitano, T; Matsuno, H; Matsushita, I; Ochiai, H; Tsuji, H | 1 |
Fukumoto, M; Okamoto, M; Suda, H | 1 |
Ando, J; Inokuma, S; Ito, K; Kiyosawa, H; Kobayashi, S; Nozawa, F; Sakata, M | 1 |
Hirohata, S; Inoue, T; Ito, K; Iwamoto, S; Kawashima, C; Kisaki, T; Nishioka, Y; Sawada, T; Shinohara, S; Tohma, S | 1 |
Doyle, DV; Ensor, M; Foster, OJ; Perrett, D; Scott, DL | 1 |
In, H; Ito, S; Kikuchi, M; Nakano, M; Ozawa, T; Saeki, T; Saito, T; Sato, T; Suzuki, S; Ueno, M | 1 |
Hashimoto, K; Lipsky, PE | 1 |
Nobunaga, M; Yasuda, M | 1 |
Hirohata, S; Lipsky, PE | 1 |
Hayakawa, M; Ikoma, T; Inokuma, S; Inoue, S; Negishi, M; Satou, T; Sayama, T; Shimizu, H; Ueda, A; Urano, Y | 1 |
Inokuma, S; Kiyosawa, H; Sakata, M; Shiratori, K; Yoshida, A | 1 |
Arakawa, M; Hasegawa, H; Nakano, M; Nishi, S; Saito, T; Ueno, M | 1 |
Furukawa, H; Hashimoto, S; Inoue, T; Ito, K; Sawada, T; Tohma, S | 1 |
Kim, HA; Song, YW | 1 |
Hashimoto, H; Hirohata, S; Nakamura, H; Ochi, T; Tomita, T; Yanagida, T; Yoshino, S | 1 |
Houki, N; Ichibangase, Y; Nobunaga, M; Yamamoto, M; Yasuda, M | 1 |
Kawada, A; Kimura, M | 1 |
Kubo, T; Matsuno, H; Matsuura, K; Muraguchi, A; Nezuka, T; Sugiyama, E; Tsuji, H | 1 |
De Miguel, E; Hernanz, A; Martín-Mola, E; Plaza, A | 1 |
Hara, S; Hideyuki, K; Mikami, A; Mori, T; Nakase, K; Sawa, N; Tachibana, S; Tagami, T; Takemoto, F; Ubara, Y; Yamada, A; Yokoyama, K | 1 |
Blake, DR; Grootveld, M; Lynch, EJ; Patel, IY; Silwood, CJ | 1 |
Kumagai, S; Morinobu, A; Wang, Z | 1 |
Hirata, D; Iwamoto, M; Kamimura, T; Kano, S; Masuyama, JI; Mimori, A; Minota, S; Okazaki, H; Sato, H; Yoshio, T | 1 |
Hefferton, D; Rahman, P; Robb, D | 1 |
Asano, G; Nagashima, M; Yoshino, S | 1 |
Aono, H; Hirano, D; Ishigami, S; Nagashima, M; Sasano, M; Takai, M; Wauke, K; Yoshino, S | 1 |
Kanazawa, M; Kawabata, Y; Matsushima, H; Motegi, M; Sakamoto, T; Sugita, Y; Takayanagi, N; Ubukata, M; Yanagisawa, T | 1 |
Hla, T; Inoue , K; Kawahito, Y; Kohno, M; Sano, H; Tsubouchi, Y | 1 |
Ji, JD; Kang, KH; Kim, HK; Kim, YR; Lee, JH; Lee, YH; Shim, JJ; Song, GG | 1 |
Hara, M; Hara, S; Matsushita, H; Nagahama, K; Ubara, Y; Yamada, A | 1 |
Hanaoka, R; Hanyuda, M; Ide, H; Kaga, S; Kasama, T; Miwa, Y; Negishi, M; Shiozawa, F | 1 |
Fujii, K; Kishimoto, N | 1 |
Maini, RN; Roffe, L; Room, G | 1 |
Kretzschmar, R; Worstmann, W | 1 |
Goto, K; Nakahara, K; Tanaka, H | 1 |
Fujinami, T; Koyama, K; Morozumi, K; Oikawa, T; Takeda, A; Yoshida, A | 1 |
Arai, T; Fujigaki, Y; Hishida, A; Ikegaya, N; Isozaki, T; Kaneko, E; Kimura, M | 1 |
Eguchi, K; Fukuda, T; Ida, H; Ishimaru, T; Kawakami, A; Nakashima, M; Sakai, M; Shimada, H; Terada, K; Yamashita, I | 1 |
Emery, P; Waring, RH | 1 |
Fukushima, T; Hashimoto, M; Ide, H; Kaga, S; Kasama, T; Kobayashi, K; Negishi, M; Tabata, M; Takahashi, T; Yamagata, N | 1 |
Fujinami, T; Ikeda, M; Koyama, K; Morozumi, K; Oikawa, T; Suganuma, T; Sugito, K; Takeda, A; Yoshida, A | 1 |
Arimori, S; Ichikawa, Y; Shimizu, H | 1 |
Amasaki, Y; Atsumi, T; Fujisaku, A; Jodo, S; Kobayashi, H; Mukai, M; Nakabayashi, T; Nakagawa, S; Sagawa, A; Watanabe, I | 1 |
Baba, N; Nomura, T; Sakemi, T; Uchida, M; Watanabe, T | 1 |
Baggott, JE; Morgan, SL; Refsum, H; Ueland, PM | 1 |
Iwainaka, Y; Kawano, M; Koni, I; Nakashima, A; Nomura, H; Takeda, R; Tofuku, Y | 1 |
Goto, M; Nishioka, K; Sasano, M | 1 |
Hidano, A; Oryu, F; Yamaguchi, R | 1 |
Bird, HA; Dixon, JS; Martin, MF; McKenna, F; Wright, V | 1 |
Ishikawa, K; Sakaguchi, M | 1 |
Baker, LR; Greenwood, RN; Matthey, F; Perrett, D | 1 |
Beyer, J; Boesen, PD; Helin, P; Hørslev-Petersen, K | 1 |
Bird, H; Dixon, J; Hickling, P; McKenna, F | 1 |
Danielewicz, H; Kosowska, E | 1 |
Dancewicz, AM; Sopata, I | 1 |
Roszkowski-Sliz, W; Ryzewski, J | 1 |
Markiewicz, L; Michalak, E; Ryźewski, J | 1 |
Calick, A; Fabianek, J; Herp, A; Pigman, W | 1 |
Kosaka, S | 2 |
Krzymien, H | 1 |
Brown, JH; Mackey, HK | 1 |
Anderson, AJ | 1 |
21 review(s) available for cysteine and Rheumatoid Arthritis
Article | Year |
---|---|
Cysteinyl Leukotrienes as Potential Pharmacological Targets for Cerebral Diseases.
Topics: Animals; Arthritis, Rheumatoid; Cardiovascular Diseases; Central Nervous System Diseases; Cysteine; Dermatitis, Atopic; Humans; Leukotrienes; Neurodegenerative Diseases | 2017 |
Cysteine cathepsins in extracellular matrix remodeling: Extracellular matrix degradation and beyond.
Topics: Arthritis, Rheumatoid; Cathepsins; Cysteine; Cysteine Endopeptidases; Extracellular Matrix; Heart Diseases; Humans; Inflammation; Lysosomes; Neoplasms; Proteolysis | 2019 |
[DMARDs (disease-modifying antirheumatic drugs)].
Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Cysteine; Humans; Japan; Methotrexate; Sulfasalazine; Tacrolimus | 2013 |
[DMARDs (Focusing on iguratimod)].
Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Chromones; Cysteine; Drug Discovery; Drug Interactions; Drug Substitution; Drug Therapy, Combination; Drugs, Generic; Female; Humans; Male; Ribonucleosides; Sulfasalazine; Sulfonamides; Tacrolimus | 2016 |
[Antirheumatic agents for treatment of rheumatoid arthritis].
Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Cysteine; Gold Sodium Thiomalate; Humans; Isoxazoles; Leflunomide; Methotrexate; Pharmacogenetics; Randomized Controlled Trials as Topic; Remission Induction; Sulfasalazine; Time Factors | 2008 |
[Effect of disease modifying anti-rheumatic drugs on radiographic progression in rheumatoid arthritis].
Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Cyclosporine; Cysteine; Disease Progression; Drug Therapy, Combination; Gold Sodium Thiomalate; Humans; Isoxazoles; Leflunomide; Methotrexate; Penicillamine; Radiography; Randomized Controlled Trials as Topic; Sulfasalazine; Tacrolimus | 2009 |
Bucillamine-induced yellow nail in Japanese patients with rheumatoid arthritis: two case reports and a review of 36 reported cases.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Cysteine; Female; Humans; Male; Yellow Nail Syndrome | 2013 |
[Treatment of rheumatic diseases: current status and future prospective. Topics: II. Immunosuppressant/antirheumatic drugs; 6. Bucillamine and gold (gold sodium thiomalate and auranofin)].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis, Rheumatoid; Auranofin; Cysteine; Gold Sodium Thiomalate | 2011 |
[ Bone and cartilage destruction in RA and its intervention. Disease-modifying antirheumatic drugs].
Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Bone and Bones; Cartilage; Clinical Trials as Topic; Cysteine; Humans; Isoxazoles; Joints; Leflunomide; Methotrexate; Sulfasalazine; Tacrolimus | 2012 |
[Bucillamine-induced dermatomyositis-like clinical features in a patient with rheumatoid arthritis].
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Cysteine; Dermatomyositis; Female; Humans | 2005 |
[Disease modifying anti-rheumatic drugs (DMARDs): an overview].
Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Benzopyrans; Cysteine; Evidence-Based Medicine; Gold Sodium Thiomalate; Humans; Isoxazoles; Leflunomide; Meta-Analysis as Topic; Methotrexate; Randomized Controlled Trials as Topic; Sulfasalazine; Sulfonamides | 2005 |
Bucillamine-induced toxic epidermal necrolysis and fixed drug eruption.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Biopsy, Needle; Cysteine; Drug Eruptions; Female; Follow-Up Studies; Humans; Immunohistochemistry; Long-Term Care; Middle Aged; Risk Assessment; Severity of Illness Index; Stevens-Johnson Syndrome | 2005 |
[Effective combination therapy of TNF antagonists with DMARDs].
Topics: Adalimumab; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antirheumatic Agents; Arthritis, Rheumatoid; Azathioprine; Cysteine; Drug Therapy, Combination; Etanercept; Humans; Hydroxychloroquine; Immunoglobulin G; Infliximab; Isoxazoles; Leflunomide; Methotrexate; Receptors, Tumor Necrosis Factor; Sulfasalazine; Tumor Necrosis Factor-alpha | 2007 |
A case with life-threatening interstitial pneumonia associated with bucillamine treatment.
Topics: Aged, 80 and over; Antioxidants; Arthritis, Rheumatoid; Cysteine; Female; Humans; Lung Diseases, Interstitial | 2008 |
Disease-modifying antirheumatic drugs, including methotrexate, gold, antimalarials, and D-penicillamine.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antimalarials; Antirheumatic Agents; Arthritis, Rheumatoid; Clinical Trials as Topic; Cysteine; Drug Therapy, Combination; Gold; Humans; Methotrexate; Penicillamine; Sulfasalazine | 1995 |
Disease-modifying antirheumatic drugs, including methotrexate, sulfasalazine, gold, antimalarials, and penicillamine.
Topics: Age Factors; Antimalarials; Arthritis, Rheumatoid; Clinical Trials as Topic; Cysteine; Digestive System; Gold; Humans; Liver; Methotrexate; Penicillamine; Sulfasalazine | 1994 |
[Drug-induced renal disorders in patients with rheumatoid arthritis].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis, Rheumatoid; Cyclosporine; Cysteine; Humans; Kidney Diseases; Methotrexate; ortho-Aminobenzoates | 1996 |
[A case of pulmonary infiltration with eosinophilia (PIE) syndrome induced by bucillamine treatment of rheumatoid arthritis].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Cysteine; Drug Eruptions; Female; Humans; Lung; Middle Aged; Pulmonary Eosinophilia | 2002 |
Bucillamine (a new therapeutic agent for rheumatoid arthritis) induced nephrotic syndrome: a report of two cases and review of the literature.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Cysteine; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Nephrotic Syndrome; Structure-Activity Relationship; Sulfhydryl Compounds | 1992 |
Management of early inflammatory arthritis. Genetic factors predicting persistent disease: the role of defective enzyme systems.
Topics: Acetaminophen; Arthritis, Rheumatoid; Carbocysteine; Cysteine; Forecasting; Humans; Inactivation, Metabolic; Methylation; Methyltransferases; Oxidation-Reduction; Sulfates | 1992 |
"Yellow nail syndrome" and rheumatoid arthritis.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Cysteine; Female; Humans; Male; Middle Aged; Nail Diseases; Nails; Penicillamine; Syndrome | 1991 |
12 trial(s) available for cysteine and Rheumatoid Arthritis
Article | Year |
---|---|
Addition of another disease-modifying anti-rheumatic drug to methotrexate reduces the flare rate within 2 years after infliximab discontinuation in patients with rheumatoid arthritis: an open, randomized, controlled trial.
Topics: Adult; Aged; Antibodies, Monoclonal; Antirheumatic Agents; Arthritis, Rheumatoid; Cysteine; Disease Progression; Drug Therapy, Combination; Female; Humans; Infliximab; Male; Methotrexate; Middle Aged; Treatment Outcome; Young Adult | 2014 |
A comparative study of the effects of bucillamine and salazosulfapyridine in the treatment of rheumatoid arthritis.
Topics: Antirheumatic Agents; Arthritis, Rheumatoid; C-Reactive Protein; Cysteine; Drug Therapy, Combination; Female; Hand Strength; Health Status; Humans; Joints; Male; Middle Aged; Pain; Prednisolone; Severity of Illness Index; Sulfasalazine; Time Factors; Treatment Outcome | 2009 |
A multicentre trial of bucillamine in the treatment of early rheumatoid arthritis (SNOW study).
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis, Rheumatoid; Child; Cysteine; Early Diagnosis; Female; Humans; Male; Methotrexate; Middle Aged; Patient Dropouts; Remission Induction; Treatment Outcome; Young Adult | 2011 |
Efficacy and safety of additional use of tacrolimus in patients with early rheumatoid arthritis with inadequate response to DMARDs--a multicenter, double-blind, parallel-group trial.
Topics: Adult; Antirheumatic Agents; Arthritis, Rheumatoid; Cysteine; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Immunosuppressive Agents; Joints; Male; Methotrexate; Middle Aged; Severity of Illness Index; Sulfasalazine; Tacrolimus; Treatment Outcome | 2011 |
Clinical course of bucillamine-induced nephropathy in patients with rheumatoid arthritis.
Topics: Adult; Aged; Antirheumatic Agents; Arthritis, Rheumatoid; Cysteine; Disease Progression; Dose-Response Relationship, Drug; Female; Glomerulonephritis, Membranous; Humans; Kidney; Kidney Function Tests; Male; Middle Aged; Proteinuria | 2003 |
Efficacy profile of bucillamine in rheumatoid arthritis patients in a large observational cohort study, IORRA.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Cohort Studies; Cysteine; Drug Therapy, Combination; Female; Health Status; Humans; Joints; Male; Methotrexate; Middle Aged; Pain; Prednisolone; Prospective Studies; Remission Induction; Severity of Illness Index; Sulfasalazine | 2006 |
Efficacy of additive DMARD therapy in patients with rheumatoid arthritis. Double blind controlled trial using bucillamine and placebo with maintenance doses of gold sodium thiomalate.
Topics: Aged; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Child, Preschool; Cysteine; Double-Blind Method; Drug Combinations; Female; Gold Sodium Thiomalate; Humans; Life Tables; Male; Middle Aged; Placebos; Prospective Studies; Time Factors; Treatment Outcome | 1994 |
Comparison of clinical effects of bucillamine between additive combination and single administration study in rheumatoid arthritis.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Cysteine; Double-Blind Method; Drug Therapy, Combination; Humans | 1993 |
A comparison between bucillamine and D-penicillamine in the treatment of rheumatoid arthritis.
Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis, Rheumatoid; Cysteine; Female; Humans; Male; Middle Aged; Penicillamine | 1997 |
Homocysteine levels in patients with rheumatoid arthritis treated with low-dose methotrexate.
Topics: Arthritis, Rheumatoid; Cysteine; Double-Blind Method; Female; Folic Acid; Homocysteine; Humans; Male; Methotrexate | 1991 |
SA 96 (N-(2-mercapto-2-methylpropanoyl)-L-cysteine) in rheumatoid arthritis.
Topics: Adult; Aged; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Chemical and Drug Induced Liver Injury; Clinical Trials as Topic; Cysteine; Drug Eruptions; Elasticity; Female; Gold; Humans; Middle Aged; Penicillamine; Tensile Strength; Time Factors | 1986 |
Rheumatoid arthritis: supplemental L-cysteine in penicillamine treatment--a controlled study.
Topics: Adult; Aged; Arthritis, Rheumatoid; Clinical Trials as Topic; Cysteine; Female; Humans; Male; Middle Aged; Penicillamine | 1985 |
107 other study(ies) available for cysteine and Rheumatoid Arthritis
Article | Year |
---|---|
Bucillamine in the treatment of patients with mild to moderate COVID-19: an interview with Michael Frank.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Clinical Trials, Phase III as Topic; COVID-19; COVID-19 Drug Treatment; Cysteine; Drug Industry; Drug Repositioning; Gout; Humans | 2022 |
[Mechanism of active ingredients in Periploca forrestii compound against rheumatoid arthritis based on integrative metabolomics and network pharmacology].
Topics: Animals; Arthritis, Rheumatoid; Biomarkers; Chromatography, High Pressure Liquid; Cysteine; Cytidine Diphosphate Choline; Glycerophospholipids; Metabolomics; Methionine; Network Pharmacology; Periploca; Phosphorylcholine; Purines; Rats | 2023 |
A novel series of cysteine-dependent, allosteric inverse agonists of the nuclear receptor RORγt.
Topics: Allosteric Site; Animals; Arthritis, Rheumatoid; Cell Differentiation; Collagen; Cysteine; Disease Models, Animal; Humans; Hydroxycholesterols; Interleukin-17; Ligands; Mice; Molecular Dynamics Simulation; Mutagenesis; Nuclear Receptor Subfamily 1, Group F, Member 3; Protein Binding; Protein Conformation; Pyrimidines; Structure-Activity Relationship; Th17 Cells | 2020 |
S-Propargyl-Cysteine Remodels the Gut Microbiota to Alleviate Rheumatoid Arthritis by Regulating Bile Acid Metabolism.
Topics: Animals; Arthritis, Rheumatoid; Bile Acids and Salts; Cysteine; Gastrointestinal Microbiome; Male; Rats; Rats, Sprague-Dawley; RNA, Ribosomal, 16S | 2021 |
Cartilage oligomeric matrix protein forms protein complexes with synovial lubricin via non-covalent and covalent interactions.
Topics: Arthritis; Arthritis, Rheumatoid; Binding Sites; Cartilage Oligomeric Matrix Protein; Cartilage, Articular; Cysteine; Glycoproteins; Humans; Osteoarthritis; Protein Binding; Spondylarthritis; Synovial Fluid | 2017 |
Hyperplasia of Lymphoid Follicles and Lymphangiectasia in the Parietal Pleura in Bucillamine-induced Yellow Nail Syndrome.
Topics: Adrenal Cortex Hormones; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Cysteine; Female; Humans; Hyperplasia; Inflammation; Lymphangiectasis; Lymphedema; Pleurisy; Yellow Nail Syndrome | 2018 |
Bucillamine-induced Pneumonitis in a Patient with Rheumatoid Arthritis-associated Interstitial Pneumonia: A Case Report and Review of the Literature.
Topics: Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Bronchoalveolar Lavage Fluid; Cysteine; Dyspnea; Female; Humans; Hypoxia; Lung; Lung Diseases, Interstitial; Lymphocyte Count; Pneumonia; Tomography, X-Ray Computed | 2019 |
Bucillamine-induced Pneumonitis in a Patient with Rheumatoid Arthritis-associated Interstitial Pneumonia: A Case Report and Review of the Literature.
Topics: Arthritis, Rheumatoid; Cysteine; Humans; Lung Diseases, Interstitial; Patients; Pneumonia | 2019 |
Bucillamine-induced Pneumonitis in a Patient with Rheumatoid Arthritis-associated Interstitial Pneumonia: A Case Report and Review of the Literature - Reply.
Topics: Arthritis, Rheumatoid; Cysteine; Humans; Lung Diseases, Interstitial; Patients; Pneumonia | 2019 |
Effective treatment of a steroid-induced femoral neck fracture nonunion with a once-weekly administration of teriparatide in a rheumatoid patient: a case report.
Topics: Aged, 80 and over; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Bone Density Conservation Agents; Cysteine; Female; Femoral Neck Fractures; Fractures, Ununited; Glucocorticoids; Humans; Osteoporosis; Prednisolone; Teriparatide; Treatment Outcome | 2013 |
Bucillamine-induced pemphigus vulgaris.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Cysteine; Drug Eruptions; Female; Humans; Pemphigus | 2015 |
The usefulness of a new triple combination treatment utilizing methotrexate, salazosulfapyridine, and bucillamine in rheumatoid arthritis.
Topics: Adult; Aged; Antirheumatic Agents; Arthritis, Rheumatoid; Biological Products; Cysteine; Drug Therapy, Combination; Female; Humans; Japan; Male; Methotrexate; Middle Aged; Sulfasalazine; Treatment Outcome | 2016 |
S-propargyl-cysteine attenuates inflammatory response in rheumatoid arthritis by modulating the Nrf2-ARE signaling pathway.
Topics: Animals; Anti-Inflammatory Agents; Antioxidant Response Elements; Arthritis, Rheumatoid; Cell Line; Cell Movement; Cell Survival; Cysteine; Disease Models, Animal; Dose-Response Relationship, Drug; Humans; Male; NF-E2-Related Factor 2; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Signal Transduction; Up-Regulation | 2016 |
Systemic delivery of small interfering RNA targeting nuclear factor κB in mice with collagen-induced arthritis using arginine-histidine-cysteine based oligopeptide-modified polymer nanomicelles.
Topics: Animals; Arginine; Arthritis, Experimental; Arthritis, Rheumatoid; Collagen; Cysteine; Cytokines; Disease Models, Animal; Histidine; Inflammation; Male; Mice; Mice, Inbred DBA; Micelles; Nanoparticles; NF-kappa B; Oligopeptides; Polymers; RNA, Messenger; RNA, Small Interfering; Synovial Membrane; Synoviocytes; Transcription Factor RelA | 2016 |
The efficacy and safety of bucillamine as a second-line DMARD in the treatment of rheumatoid arthritis: a retrospective cohort study.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis, Rheumatoid; Cohort Studies; Cysteine; Female; Health Status; Humans; Joints; Male; Middle Aged; Remission Induction; Retrospective Studies; Severity of Illness Index; Treatment Outcome | 2008 |
[False-positive reaction of urinary ketone bodies caused by bucillamine].
Topics: Aged; Antirheumatic Agents; Arthritis, Rheumatoid; Biomarkers; Cysteine; False Positive Reactions; Female; Humans; Ketone Bodies; Male; Middle Aged | 2008 |
Etanercept improved primary biliary cirrhosis associated with rheumatoid arthritis.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis, Rheumatoid; Cysteine; Drug Therapy, Combination; Etanercept; Female; Humans; Immunoglobulin G; Liver Cirrhosis, Biliary; Methotrexate; Middle Aged; Prednisolone; Receptors, Tumor Necrosis Factor; Treatment Outcome; Withholding Treatment | 2009 |
Differential influences of bucillamine and methotrexate on the generation of fibroblast-like cells from bone marrow CD34+ cells of rheumatoid arthritis patients.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Antigens, CD34; Antirheumatic Agents; Arthritis, Rheumatoid; Bone Marrow Cells; Culture Media; Cysteine; Female; Fibroblasts; Fluorescent Antibody Technique; Humans; Ilium; Immunosuppressive Agents; Indicators and Reagents; Matrix Metalloproteinase 1; Methotrexate; Middle Aged; Stem Cells; Vimentin | 2009 |
The investigation of synovial genomic targets of bucillamine with microarray technique.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Cells, Cultured; Cysteine; Gene Expression Profiling; Gene Expression Regulation; Humans; Interleukin-1beta; Microarray Analysis; Molecular Sequence Data; Molecular Structure; Signal Transduction; Synovial Membrane | 2009 |
Radiographic repair in three Japanese patients with rheumatoid arthritis treated with bucillamine.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Arthrography; Bone and Bones; Cysteine; Disease Progression; Female; Humans; Joints; Male; Middle Aged; Recovery of Function; Severity of Illness Index; Treatment Outcome | 2009 |
Haloacetamidine-based inactivators of protein arginine deiminase 4 (PAD4): evidence that general acid catalysis promotes efficient inactivation.
Topics: Acids; Amidines; Arthritis, Rheumatoid; Catalysis; Catalytic Domain; Cysteine; Humans; Hydrogen-Ion Concentration; Hydrolases; Kinetics; Protein-Arginine Deiminase Type 4; Protein-Arginine Deiminases | 2010 |
Combined effects of bucillamine and etanercept on a rat type II collagen-induced arthritis model.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis, Experimental; Arthritis, Rheumatoid; Cysteine; Disease Models, Animal; Drug Synergism; Drug Therapy, Combination; Etanercept; Female; Granulocyte-Macrophage Colony-Stimulating Factor; Immunoglobulin G; Immunoglobulin M; Interleukin-1alpha; Interleukin-6; Rats; Rats, Inbred Lew; Receptors, Tumor Necrosis Factor | 2010 |
Organizing pneumonia in a patient with rheumatoid arthritis treated with etanercept.
Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Cryptogenic Organizing Pneumonia; Cysteine; Drug Therapy, Combination; Etanercept; Female; Humans; Immunoglobulin G; Methotrexate; Middle Aged; Radiography, Thoracic; Receptors, Tumor Necrosis Factor; Treatment Outcome | 2010 |
Bioinorganic and medicinal chemistry: aspects of gold(I)-protein complexes.
Topics: Arthritis, Rheumatoid; Binding Sites; Catalytic Domain; Chemistry, Pharmaceutical; Coordination Complexes; Cysteine; Glutathione Reductase; Gold; Humans; Protein Tyrosine Phosphatases; Proteins; Selenocysteine; Serum Albumin | 2011 |
Etanercept in combination with conventional disease-modifying antirheumatic drugs (DMARDs) in the treatment of rheumatoid arthritis patients intolerant to methotrexate.
Topics: Adult; Aged; Aged, 80 and over; Antirheumatic Agents; Arthritis, Rheumatoid; Cysteine; Drug Substitution; Drug Therapy, Combination; Etanercept; Female; Glucocorticoids; Humans; Immunoglobulin G; Joints; Male; Methotrexate; Middle Aged; Pain Measurement; Receptors, Tumor Necrosis Factor; Recovery of Function; Retrospective Studies; Severity of Illness Index; Sulfasalazine; Treatment Failure | 2012 |
Single-center, retrospective analysis of efficacy and safety of tacrolimus as a second-line DMARD in combination therapy and the risk factors contributing to adverse events in 115 patients with rheumatoid arthritis.
Topics: Adult; Aged; Antirheumatic Agents; Arthritis, Rheumatoid; Cysteine; Disease Progression; Drug Therapy, Combination; Female; Humans; Male; Methotrexate; Middle Aged; Retrospective Studies; Risk Factors; Severity of Illness Index; Sulfasalazine; Tacrolimus; Treatment Outcome | 2012 |
Recent trends in use of nonbiologic DMARDs and evaluation of their continuation rates in single and dual combination therapies in rheumatoid arthritis patients in Japan.
Topics: Adult; Antirheumatic Agents; Arthritis, Rheumatoid; Cysteine; Drug Therapy, Combination; Female; Humans; Japan; Male; Methotrexate; Practice Patterns, Physicians'; Severity of Illness Index; Sulfasalazine; Treatment Outcome | 2012 |
[Rheumatoid arthritis: progress in diagnosis and treatment. Topics: IV. Treatment; 2. Antirheumatic agents, 1) non-biologic agents].
Topics: Antirheumatic Agents; Arthritis, Rheumatoid; Cysteine; Female; Humans; Methotrexate; Sulfasalazine; Tacrolimus | 2012 |
Cysteine dioxygenase: modulation of expression in human cell lines by cytokines and control of sulphate production.
Topics: Antineoplastic Agents; Arthritis, Rheumatoid; Cell Line; Cysteine; Cysteine Dioxygenase; Dioxygenases; Humans; Inflammation; Liver; Neurons; Oxygenases; Sulfates; Transforming Growth Factor beta; Tumor Necrosis Factor-alpha | 2002 |
Gigantomastia induced by bucillamine.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Breast; Breast Diseases; Cysteine; Female; Humans; Hyperplasia; Hypertrophy; Mammaplasty; Treatment Outcome | 2002 |
Depolymerization of the 19S antibodies and the 22S rheumatoid factor.
Topics: Antibodies; Arthritis; Arthritis, Rheumatoid; Cysteine; Humans; Rheumatoid Factor | 1958 |
Moderate hyperhomocysteinaemia and immune activation in patients with rheumatoid arthritis.
Topics: Adult; Aged; Antigens, CD; Arthritis, Rheumatoid; Cysteine; Female; Homocysteine; Humans; Hyperhomocysteinemia; Male; Middle Aged; Receptors, Tumor Necrosis Factor; Receptors, Tumor Necrosis Factor, Type II; Vitamin B 12 | 2003 |
Patients with rheumatoid arthritis (RA) and proteinuria.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Cysteine; Humans; Proteinuria | 2004 |
[Examination of the escape phenomenon in disease modifying antirheumatic drugs].
Topics: Aged; Antirheumatic Agents; Arthritis, Rheumatoid; Blood Sedimentation; C-Reactive Protein; Cysteine; Drug Therapy, Combination; Female; Humans; Male; Methotrexate; Middle Aged; Phenylacetates; Recurrence; Secondary Prevention; Sulfasalazine | 2005 |
The inhibitory effect of disease-modifying anti-rheumatic drugs and steroids on gliostatin/platelet-derived endothelial cell growth factor production in human fibroblast-like synoviocytes.
Topics: Adrenal Cortex Hormones; Adult; Aged; Antirheumatic Agents; Arthritis, Rheumatoid; Cells; Cells, Cultured; Cysteine; Dexamethasone; Elbow; Female; Fibroblasts; Humans; Knee; Methotrexate; Middle Aged; Organogold Compounds; Orthopedic Procedures; Penicillamine; Phenylacetates; Sulfasalazine; Synovial Membrane; Thymidine Phosphorylase | 2005 |
Efficacy and safety of bucillamine, a D-penicillamine analogue, in patients with active rheumatoid arthritis.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; C-Reactive Protein; Cysteine; Female; Humans; Joints; Male; Methotrexate; Middle Aged; Retrospective Studies; Severity of Illness Index; Treatment Outcome | 2006 |
Outcome and treatment of bucillamine-induced nephropathy.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Cysteine; Drug Administration Schedule; Female; Glomerulonephritis, Membranous; Humans; Kidney; Male; Middle Aged; Proteinuria; Remission Induction | 2006 |
Bucillamine-induced pemphigus vulgaris in a patient with rheumatoid arthritis and polymyositis overlap syndrome.
Topics: Antioxidants; Arthritis; Arthritis, Rheumatoid; Biopsy; Cysteine; Female; Humans; Middle Aged; Pemphigus; Polymyositis; Skin; Syndrome | 2006 |
Radiographic appearance of bronchiolitis obliterans organizing pneumonia (BOOP) developing during Bucillamine treatment for rheumatoid arthritis.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Cryptogenic Organizing Pneumonia; Cysteine; Female; Humans; Lung; Radiography | 2006 |
Yellow nails under bucillamine therapy for rheumatoid arthritis: a report of two cases.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Cysteine; Female; Humans; Middle Aged; Nail Diseases; Pigmentation Disorders | 2007 |
Scientific basis for the efficacy of combined use of antirheumatic drugs against bone destruction in rheumatoid arthritis.
Topics: Animals; Antirheumatic Agents; Arthritis, Rheumatoid; Bone Resorption; Cell Differentiation; Cells, Cultured; Coculture Techniques; Cysteine; Dose-Response Relationship, Drug; Drug Therapy, Combination; Methotrexate; Mice; Mice, Inbred C57BL; NFATC Transcription Factors; Osteoclasts; RANK Ligand; Sulfasalazine | 2007 |
Ten years results of bucillamine in the treatment of rheumatoid arthritis.
Topics: Adult; Aged; Antirheumatic Agents; Arthritis, Rheumatoid; Cohort Studies; Cysteine; Female; Follow-Up Studies; Humans; Male; Middle Aged; Patient Dropouts; Severity of Illness Index; Treatment Outcome | 2007 |
A case of bucillamine-induced interstitial pneumonia with positive lymphocyte stimulation test for bucillamine using bronchoalveolar lavage lymphocytes.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Bronchoalveolar Lavage Fluid; Cysteine; Female; Humans; Lung; Lung Diseases, Interstitial; Lymphocyte Activation; Middle Aged; Radiography | 2007 |
Hemophagocytic syndrome associated with rheumatoid arthritis.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Cysteine; Female; Humans; Lymphohistiocytosis, Hemophagocytic; Middle Aged | 2007 |
Eosinophilic pneumonia (EP) associated with rheumatoid arthritis in which drug-induced eosinophilic pneumonia could be ruled out.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis, Rheumatoid; Cysteine; Diagnosis, Differential; Glucocorticoids; Humans; Male; Methotrexate; Prednisolone; Pulmonary Eosinophilia | 2008 |
D-Penicillamine induced toxicity in rheumatoid arthritis: the role of sulphoxidation status and HLA-DR3.
Topics: Adult; Aged; Arthritis, Rheumatoid; Biotransformation; Carbocysteine; Cysteine; Female; Histocompatibility Antigens Class II; HLA-DR3 Antigen; HLA-DR4 Antigen; Humans; Male; Middle Aged; Penicillamine; Risk | 1984 |
Studies on the metabolism of D-penicillamine and its interaction with probenecid in cystinuria and rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Cysteine; Cystinuria; Drug Therapy, Combination; Female; Humans; Male; Penicillamine; Pilot Projects; Probenecid; Time Factors | 1984 |
D-penicillamine in patients with rheumatoid arthritis. Serum levels, pharmacokinetic aspects, and correlation with clinical course and side effects.
Topics: Arthritis, Rheumatoid; Cysteine; Drug Administration Schedule; Humans; Intestinal Absorption; Kinetics; Penicillamine; Time Factors | 1984 |
Pharmacokinetics of the major metabolites of D-penicillamine in patients with rheumatoid arthritis.
Topics: Adult; Aged; Arthritis, Rheumatoid; Biotransformation; Chromatography, High Pressure Liquid; Cysteine; Dose-Response Relationship, Drug; Female; Humans; Metabolic Clearance Rate; Middle Aged; Penicillamine | 1984 |
Yellow nail induced by bucillamine.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Cysteine; Humans; Male; Nail Diseases | 1995 |
[Immunoglobulin and LST in RA patients treated with bucillamine].
Topics: Aged; Arthritis, Rheumatoid; Cysteine; Female; Humans; Immunoglobulins; Lymphocyte Activation; Male; Middle Aged | 1995 |
Plasma thiols, copper and rheumatoid arthritis.
Topics: Animals; Arthritis, Rheumatoid; Copper; Cysteine; Glutathione; Homocysteine; Humans; Methionine; Methotrexate; Models, Biological; Sulfhydryl Compounds | 1994 |
[A case of rheumatoid arthritis associated with agranulocytosis during bucillamine treatment].
Topics: Agranulocytosis; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Cysteine; Female; Humans; Middle Aged | 1994 |
Immunopharmacological evaluation of bucillamine in rheumatoid arthritis.
Topics: Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; CD4 Antigens; Cysteine; Female; Flow Cytometry; Hemagglutination Tests; Humans; Male; Middle Aged; T-Lymphocyte Subsets | 1993 |
Delayed-type skin allergic reaction in guinea pigs induced by anti-rheumatic compounds with sulfhydryl groups.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Cysteine; Dermatitis, Allergic Contact; Drug Hypersensitivity; Guinea Pigs; Humans; Hypersensitivity, Delayed; Immunochemistry; Male; Species Specificity; Structure-Activity Relationship; Sulfhydryl Compounds | 1993 |
[Immunoglobulin decrease accompanying adverse reactions with bucillamine].
Topics: Agammaglobulinemia; Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Cysteine; Female; Humans; Immunoglobulin A; Immunoglobulin G; Immunoglobulin M; Male; Middle Aged | 1993 |
[Analysis of the state of patients with rheumatoid arthritis using a personal computer].
Topics: Age Factors; Arthritis, Rheumatoid; Cysteine; Databases, Factual; Female; Gold Sodium Thiomalate; Humans; Male; Microcomputers; Middle Aged; Penicillamine; Quality of Life; Time Factors | 1993 |
The long-term use of D-penicillamine for treating rheumatoid arthritis: is continuous therapy necessary?
Topics: Adult; Aged; Aged, 80 and over; Arthritis, Rheumatoid; Chromatography, High Pressure Liquid; Clinical Protocols; Cysteine; Dose-Response Relationship, Drug; Female; Humans; Male; Middle Aged; Patient Compliance; Penicillamine; Time Factors | 1993 |
[Clinicopathological evaluation and treatment of bucillamine induced membranous nephropathy].
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Cysteine; Female; Glomerulonephritis, Membranous; Humans; Kidney; Male; Middle Aged | 1993 |
Immunosuppression by the disease modifying antirheumatic drug bucillamine: inhibition of human T lymphocyte function by bucillamine and its metabolites.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Catalase; Cysteine; Humans; Immunosuppressive Agents; In Vitro Techniques; Interleukin-2; Lymphocyte Activation; Molecular Structure; T-Lymphocytes | 1993 |
Regulation of B cell function by bucillamine, a novel disease-modifying antirheumatic drug.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; B-Lymphocytes; Copper; Cysteine; Depression, Chemical; Humans; Immunoglobulin M; Lymphocyte Activation; Penicillamine | 1993 |
[Bucillamin induced lung injury in rheumatoid arthritis].
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Cysteine; Diagnosis, Differential; Female; Humans; Lung Diseases; Male; Middle Aged; Tomography, X-Ray Computed | 1996 |
Bucillamine induced pulmonary injury occurs with immunoglobulin decrease.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Cysteine; Female; Humans; Immunoglobulin A; Immunoglobulin G; Immunoglobulin M; Immunoglobulins; Lung Diseases; Lung Diseases, Interstitial; Radiography | 1996 |
Generation of reactive oxygen species is required for bucillamine, a novel anti-rheumatic drug, to induce apoptosis in concert with copper.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Arthritis, Rheumatoid; Cell Line; Copper; Cysteine; Drug Synergism; Humans; Monocytes; Reactive Oxygen Species | 1997 |
Differential influences of gold sodium thiomalate and bucillamine on the generation of CD14+ monocyte-lineage cells from bone marrow of rheumatoid arthritis patients.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis, Rheumatoid; Bone Marrow; Bone Marrow Cells; Cell Lineage; Cysteine; Female; Gold Sodium Thiomalate; HLA-DR Antigens; Humans; Lipopolysaccharide Receptors; Male; Middle Aged; Monocytes | 1997 |
Induction of drug resistance to gold sodium thiomalate in a monocyte cell line, THP-1.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blotting, Western; Cell Line; Cysteine; Cytoplasm; Dose-Response Relationship, Drug; Drug Resistance; Fluorescent Antibody Technique, Indirect; Gold Sodium Thiomalate; Humans; Metallothionein; Monocytes; Sensitivity and Specificity | 1998 |
Drug eruption due to bucillamine.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Cysteine; Drug Eruptions; Female; Humans; Middle Aged; Patch Tests | 1998 |
Pharmacological effects of SA96 (bucillamine) and its metabolites as immunomodulating drugs--the disulfide structure of SA-96 metabolites plays a critical role in the pharmacological action of the drug.
Topics: Adjuvants, Immunologic; Adult; Aged; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis, Rheumatoid; Cells, Cultured; Cysteine; Disulfides; Female; Gas Chromatography-Mass Spectrometry; Humans; Interleukin-6; Interleukin-8; Male; Middle Aged; Penicillamine; Rats; Structure-Activity Relationship; Synovial Fluid | 1998 |
Increased plasma levels of homocysteine and other thiol compounds in rheumatoid arthritis women.
Topics: Adult; Amino Acids; Arthritis, Rheumatoid; Cysteine; Female; Folic Acid; Glutathione; Glycine; Homocysteine; Humans; Middle Aged; Vitamin B 12 | 1999 |
[A case of rheumatoid arthritis with bucillamine-induced myasthenia gravis treated by immunoadsorption therapy].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Cysteine; Female; Humans; Immunosorbent Techniques; Middle Aged; Myasthenia Gravis | 1999 |
The role of N-acetylcysteine in protecting synovial fluid biomolecules against radiolytically-mediated oxidative damage: a high field proton NMR study.
Topics: Acetylcysteine; Arthritis, Rheumatoid; Cysteine; Free Radicals; Gamma Rays; Humans; Knee Joint; Magnetic Resonance Spectroscopy; Oxidative Stress; Protons; Sulfhydryl Compounds; Synovial Fluid | 1999 |
Bucillamine suppresses human Th1 cell development by a hydrogen peroxide-independent mechanism.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis, Rheumatoid; CD4-Positive T-Lymphocytes; Cell Differentiation; Cells, Cultured; Cysteine; Flow Cytometry; Humans; Hydrogen Peroxide; Interferon-gamma; Interleukin-12; Interleukin-2; Interleukin-4; Leukocyte Common Antigens; Oxidants; Penicillamine; Th1 Cells | 2000 |
In vitro and in vivo inhibition of activation induced T cell apoptosis by bucillamine.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antibodies; Antirheumatic Agents; Apoptosis; Arthritis, Rheumatoid; B-Lymphocytes; CD3 Complex; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Cysteine; Dexamethasone; Enterotoxins; Flow Cytometry; Glucocorticoids; Hybridomas; In Vitro Techniques; Interleukin-2; Lymphocyte Activation; Mice; Mice, Inbred BALB C; Penicillamine; Reactive Oxygen Species; Superantigens; Thymus Gland | 2000 |
Increased MDR1 P-glycoprotein expression in methotrexate resistance: comment on the article by Yudoh et al.
Topics: Antirheumatic Agents; Arthritis, Rheumatoid; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cysteine; Drug Interactions; Drug Resistance, Multiple; Humans; Methotrexate; Sulfasalazine; Th1 Cells | 2000 |
Imbalance in production between vascular endothelial growth factor and endostatin in patients with rheumatoid arthritis.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Collagen; Cysteine; Drug Therapy, Combination; Endostatins; Endothelial Growth Factors; Enzyme-Linked Immunosorbent Assay; Fibroblast Growth Factor 2; Humans; Lymphokines; Middle Aged; Osteoarthritis; Peptide Fragments; Prednisolone; Sulfasalazine; Synovial Fluid; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors | 2000 |
Effects of combinations of anti-rheumatic drugs on the production of vascular endothelial growth factor and basic fibroblast growth factor in cultured synoviocytes and patients with rheumatoid arthritis.
Topics: Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis, Rheumatoid; C-Reactive Protein; Cells, Cultured; Cysteine; Dexamethasone; Drug Synergism; Drug Therapy, Combination; Endothelial Growth Factors; Fibroblast Growth Factor 2; Gold Sodium Thiomalate; Humans; In Vitro Techniques; Lipopolysaccharides; Lymphokines; Methotrexate; Sulfasalazine; Synovial Membrane; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors | 2000 |
[A case of drug-induced interstitial pneumonitis in rheumatoid arthritis treated with bucillamine].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Cysteine; Female; Humans; Lung Diseases, Interstitial; Lymphocyte Activation; Middle Aged; Thoracic Surgery, Video-Assisted | 2001 |
Feedback control of the arachidonate cascade in rheumatoid synoviocytes by 15-deoxy-Delta(12,14)-prostaglandin J2.
Topics: Arachidonic Acid; Arthritis, Rheumatoid; Chromans; Cyclooxygenase 2; Cysteine; Dinoprostone; Feedback; Humans; Isoenzymes; Leukotriene Antagonists; Leukotriene B4; Leukotrienes; Membrane Proteins; Prostaglandin D2; Prostaglandin-Endoperoxide Synthases; Receptors, Cytoplasmic and Nuclear; Synovial Membrane; Thiazoles; Thiazolidinediones; Transcription Factors; Troglitazone | 2001 |
A case of BOOP developed during bucillamine treatment for rheumatoid.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Biopsy, Needle; Cryptogenic Organizing Pneumonia; Cysteine; Follow-Up Studies; Humans; Male; Middle Aged; Radiography, Thoracic; Risk Assessment; Tomography, X-Ray Computed | 2001 |
Bucillamine induces membranous glomerulonephritis.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Cysteine; Dose-Response Relationship, Drug; Female; Glomerulonephritis, Membranous; Humans; Male; Middle Aged; Proteinuria | 2002 |
[A case of rheumatoid arthritis complicated with a pneumonitis during concomitant treatment with methotrexate and bucillamine].
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Antirheumatic Agents; Arthritis, Rheumatoid; Cysteine; Female; Humans; Methotrexate; Pneumonia | 2002 |
The inhibitory effect of D-penicillamine on human lymphocyte cultures stimulated by phytohaemagglutinin, the antagonistic action of L-cysteine and synergistic inhibition by copper sulphate.
Topics: Adult; Arthritis, Rheumatoid; Blood; Cells, Cultured; Copper; Culture Media; Cysteine; Drug Synergism; Humans; Lymphocyte Activation; Penicillamine; Phytohemagglutinins | 1979 |
Blood levels and side-effects of D-penicillamine.
Topics: Arthritis, Rheumatoid; Copper; Cysteine; Humans; Kinetics; Penicillamine | 1979 |
Proceedings: Antiarthritic properties of cystein derivatives in comparison with D-penicillamin in rats.
Topics: Animals; Arthritis, Rheumatoid; Cysteine; Elasticity; Female; Freund's Adjuvant; Penicillamine; Rats; Tendons | 1975 |
[A case of bucillamine-induced pneumonitis].
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Bronchoalveolar Lavage Fluid; Cysteine; Female; Gold Sodium Thiomalate; Lung; Pneumonia | 1992 |
A case of rapidly progressive glomerulonephritis associated with bucillamine-treated rheumatoid arthritis.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Biopsy; Cysteine; Female; Glomerulonephritis; Humans; Kidney; Microscopy, Electron; Middle Aged; Time Factors | 1992 |
Bucillamine inhibits T cell adhesion to human endothelial cells.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Catalase; Cell Adhesion; Cell Communication; Cells, Cultured; Copper; Copper Sulfate; Cysteine; Endothelium, Vascular; Humans; Hydrogen Peroxide; Interferon-gamma; Recombinant Proteins; Superoxide Dismutase; T-Lymphocytes; Umbilical Veins | 1992 |
[Lung injury associated with bucillamine therapy].
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Cysteine; Female; Humans; Male; Middle Aged; Pulmonary Fibrosis | 1992 |
Clinicopathological findings of bucillamine-induced nephrotic syndrome in patients with rheumatoid arthritis.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Biopsy; Cysteine; Female; Fluorescent Antibody Technique; Glomerulonephritis, Membranous; Humans; Kidney; Male; Microscopy, Electron; Middle Aged; Nephrotic Syndrome | 1991 |
[A case of rheumatoid arthritis developing pemphigus-like skin lesion during treatment with bucillamine].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Cysteine; Drug Eruptions; Female; Humans; Middle Aged; Pemphigus | 1991 |
[Membranous glomerulonephritis probably related to bucillamine therapy in two patients with rheumatoid arthritis].
Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Complement C3; Cysteine; Female; Glomerulonephritis, Membranous; Humans; Immunoglobulin G; Kidney; Male; Middle Aged | 1991 |
[Bucillamine-associated membranous nephropathy in a patient with rheumatoid arthritis].
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Cysteine; Female; Glomerulonephritis, Membranous; Humans | 1990 |
Decrease in disease activity and concomitant increase in the percentage of peripheral blood suppressor T-cells in rheumatoid arthritis by a newly synthesized slow-acting anti-rheumatic drug (Bucillamine).
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Cysteine; Female; Flow Cytometry; Fluorescent Antibody Technique; Humans; Immunoglobulin G; Leukocyte Count; Middle Aged; T-Lymphocytes, Regulatory; Time Factors | 1989 |
A case of bullous pemphigoid induced by tiobutarit (D-penicillamine analogue).
Topics: Anti-Inflammatory Agents; Arthritis, Rheumatoid; Cysteine; Female; Humans; Middle Aged; Pemphigoid, Bullous; Skin Diseases, Vesiculobullous | 1989 |
Biochemical and clinical changes occurring during the treatment of rheumatoid arthritis with novel antirheumatoid drugs.
Topics: Adult; Aged; Arthritis, Rheumatoid; Blood Viscosity; Captopril; Cysteine; Female; Humans; Male; Middle Aged; Penicillamine; Sulfasalazine; Sulfates; Zinc; Zinc Sulfate | 1985 |
The use of D-penicillamine in patients with rheumatoid arthritis undergoing hemodialysis.
Topics: Arthritis, Rheumatoid; Cysteine; Female; Humans; Kidney Failure, Chronic; Male; Middle Aged; Penicillamine; Renal Dialysis; Time Factors | 1986 |
Methylcysteine in rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Cysteine; Humans | 1986 |
A method for detecting Ig rheumatoid factors in seronegative rheumatoid arthritis.
Topics: Absorption; Animals; Antigens; Arthritis, Rheumatoid; Cysteine; Erythrocytes; gamma-Globulins; Hemagglutination Tests; Humans; Immunodiffusion; Immunoglobulin G; Immunoglobulins; Immunologic Techniques; Peptides; Polymers; Rabbits; Rheumatoid Factor; Serologic Tests | 1974 |
Presence of a gelatin-specific proteinase and its latent form in human leucocytes.
Topics: Arthritis, Rheumatoid; Chloromercuribenzoates; Chromatography, Gel; Chromatography, Ion Exchange; Collagen; Cysteine; Dithiothreitol; Edetic Acid; Electrophoresis, Polyacrylamide Gel; Enzyme Activation; Gelatin; Humans; Hydrogen-Ion Concentration; Hydroxyproline; Iodoacetates; Isoflurophate; Kinetics; Leukocytes; Peptide Hydrolases; Structure-Activity Relationship; Synovial Fluid; Temperature; Trypsin Inhibitors; Viscosity | 1974 |
The influence of DL-cysteine on adenyl cyclase activity in rat thymocytes.
Topics: Adenylyl Cyclases; Animals; Arthritis, Rheumatoid; Cysteine; Disease Models, Animal; Epinephrine; Freund's Adjuvant; Injections, Intraperitoneal; Male; Rats; Rats, Inbred Strains; Thymus Gland; Time Factors | 1974 |
Catecholamines in the lymphatic organs in rats with postadjuvant polyarthritis and after treatment with DL-cysteine hydrochloride.
Topics: Adrenal Glands; Animals; Arthritis, Rheumatoid; Catecholamines; Cysteine; Epinephrine; Female; Kidney; Liver; Lymph Nodes; Lymphatic System; Norepinephrine; Rats; Spleen; Thymus Gland; Time Factors | 1973 |
Dermal connective tissue permeability in rheumatoid arthritics.
Topics: Adult; Animals; Arthritis, Rheumatoid; Ascorbic Acid; Carbamates; Cell Membrane Permeability; Connective Tissue; Cysteine; Dye Dilution Technique; Ethanol; Humans; Hyaluronic Acid; Injections, Intradermal; Isotonic Solutions; Penicillamine; Prednisone; Rats; Skin; Sodium Salicylate; Thiourea | 1966 |
Serum sulfhydryl levels and rheumatoid factors in rheumatoid arthritis.
Topics: Adult; Arthritis, Rheumatoid; Cysteine; Female; Glutathione; Hemagglutination Tests; Humans; Immunoglobulin M; Lupus Erythematosus, Systemic; Male; Nephritis; Nephrotic Syndrome; Rheumatic Diseases; Rheumatic Fever; Rheumatoid Factor; Sulfhydryl Compounds; Synovial Fluid | 1970 |
The molybdate urine test in determination of the activity of rheumatoid arthritis.
Topics: Arthritis, Rheumatoid; Cell Division; Cysteine; Humans; Indicators and Reagents; Molybdenum; Oxidation-Reduction; Quaternary Ammonium Compounds; Urine | 1970 |
Inhibition of heat-induced denaturation of serum proteins by mixtures of nonsteroidal anti-inflammatory agents and amino acids.
Topics: Amino Acids; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Cysteine; Depression, Chemical; Flufenamic Acid; Fluorine; Histamine; Histidine; Hot Temperature; Indomethacin; ortho-Aminobenzoates; Phenylalanine; Phenylbutazone; Protein Denaturation; Serine; Serum Albumin, Bovine; Solutions; Tryptophan; Tyrosine | 1968 |
Effects of SH-compounds on rheumatoid factors in rheumatoid arthritis.
Topics: Animals; Arthritis, Rheumatoid; Blood Protein Electrophoresis; Cysteine; Hemagglutination Tests; Humans; Injections; Joints; Penicillamine; Rabbits; Rheumatoid Factor; Serologic Tests; Sulfhydryl Compounds; Synovial Fluid; Ultracentrifugation; Viscosity | 1969 |
Effects of lysosomal collagenolytic enzymes, anti-inflammatory drugs and other substances on some properties of insoluble collagen.
Topics: Animals; Anti-Inflammatory Agents; Arthritis, Rheumatoid; Cathepsins; Collagen; Copper; Cysteine; Hydroxyproline; In Vitro Techniques; Lathyrism; Liver; Lysosomes; Mucoproteins; Penicillamine; Phenylacetates; Phenylbutazone; Rats; Solubility | 1969 |