Page last updated: 2024-11-01

ofloxacin and Rheumatoid Arthritis

ofloxacin has been researched along with Rheumatoid Arthritis in 3 studies

Ofloxacin: A synthetic fluoroquinolone antibacterial agent that inhibits the supercoiling activity of bacterial DNA GYRASE, halting DNA REPLICATION.
9-fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid : An oxazinoquinoline that is 2,3-dihydro-7H-[1,4]oxazino[2,3,4-ij]quinolin-7-one substituted by methyl, carboxy, fluoro, and 4-methylpiperazin-1-yl groups at positions 3, 6, 9, and 10, respectively.
ofloxacin : A racemate comprising equimolar amounts of levofloxacin and dextrofloxacin. It is a synthetic fluoroquinolone antibacterial agent which inhibits the supercoiling activity of bacterial DNA gyrase, halting DNA replication.

Research Excerpts

ExcerptRelevanceReference
"In a 6-month, double-blind trial, we randomly assigned 76 patients with persistently active rheumatoid arthritis despite at least 6 months of methotrexate therapy at a stable dose of 15 to 25 mg per week to receive either levofloxacin (500 mg) or placebo orally once daily while continuing to receive methotrexate."9.12Levofloxacin treatment in patients with rheumatoid arthritis receiving methotrexate. ( Ogrendik, M, 2007)
"In a 6-month, double-blind trial, we randomly assigned 76 patients with persistently active rheumatoid arthritis despite at least 6 months of methotrexate therapy at a stable dose of 15 to 25 mg per week to receive either levofloxacin (500 mg) or placebo orally once daily while continuing to receive methotrexate."5.12Levofloxacin treatment in patients with rheumatoid arthritis receiving methotrexate. ( Ogrendik, M, 2007)
"We report the antiinflammatory effect and efficacy of preoperative treatment with ketorolac in a patient with rheumatoid arthritis having phacoemulsification."3.71Antiinflammatory effect of preoperative ketorolac in phacoemulsification. ( Caronia, RM; Donnenfeld, ED; Perry, HD, 2002)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chen, HW1
Lai, CC1
Tan, CK1
Caronia, RM1
Perry, HD1
Donnenfeld, ED1
Ogrendik, M1

Trials

1 trial available for ofloxacin and Rheumatoid Arthritis

ArticleYear
Levofloxacin treatment in patients with rheumatoid arthritis receiving methotrexate.
    Southern medical journal, 2007, Volume: 100, Issue:2

    Topics: Anti-Bacterial Agents; Antirheumatic Agents; Arthritis, Rheumatoid; Double-Blind Method; Drug Therap

2007

Other Studies

2 other studies available for ofloxacin and Rheumatoid Arthritis

ArticleYear
Arthritis caused by Mycobacterium terrae in a patient with rheumatoid arthritis.
    International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases, 2009, Volume: 13, Issue:4

    Topics: Adult; Anti-Bacterial Agents; Arthritis, Rheumatoid; Azithromycin; Drug Therapy, Combination; Ethamb

2009
Antiinflammatory effect of preoperative ketorolac in phacoemulsification.
    Journal of cataract and refractive surgery, 2002, Volume: 28, Issue:10

    Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Cataract; Drug Therapy, Combin

2002