2--carbodeoxyguanosine has been researched along with Glioblastoma* in 1 studies
1 other study(ies) available for 2--carbodeoxyguanosine and Glioblastoma
Article | Year |
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Multi-log cytotoxicity of carbocyclic 2'-deoxyguanosine in HSV-TK-expressing human tumor cells.
Ganciclovir (GCV) is widely used as a prodrug for selective activation in tumor cells expressing herpes simplex virus thymidine kinase (HSV-TK) because of its ability to induce multi-log cytotoxicity to HSV-TK-expressing as well as nonexpressing bystander cells. We now report that another substrate for HSV-TK, D-carbocyclic 2'-deoxyguanosine (CdG), induces multi-log cytotoxicity in HSV-TK-expressing and bystander cells at concentrations Topics: Antiviral Agents; Cell Death; Colonic Neoplasms; Deoxyguanosine; Enzyme Activation; Ganciclovir; Gene Transfer Techniques; Glioblastoma; Prodrugs; Simplexvirus; Thymidine Kinase; Tumor Cells, Cultured; Viral Proteins | 2002 |