2--carbodeoxyguanosine and Glioblastoma

2--carbodeoxyguanosine has been researched along with Glioblastoma* in 1 studies

Other Studies

1 other study(ies) available for 2--carbodeoxyguanosine and Glioblastoma

Article	Year
Multi-log cytotoxicity of carbocyclic 2'-deoxyguanosine in HSV-TK-expressing human tumor cells. Human gene therapy, 2002, Mar-01, Volume: 13, Issue:4 Ganciclovir (GCV) is widely used as a prodrug for selective activation in tumor cells expressing herpes simplex virus thymidine kinase (HSV-TK) because of its ability to induce multi-log cytotoxicity to HSV-TK-expressing as well as nonexpressing bystander cells. We now report that another substrate for HSV-TK, D-carbocyclic 2'-deoxyguanosine (CdG), induces multi-log cytotoxicity in HSV-TK-expressing and bystander cells at concentrations Topics: Antiviral Agents; Cell Death; Colonic Neoplasms; Deoxyguanosine; Enzyme Activation; Ganciclovir; Gene Transfer Techniques; Glioblastoma; Prodrugs; Simplexvirus; Thymidine Kinase; Tumor Cells, Cultured; Viral Proteins	2002

Article

Year

Multi-log cytotoxicity of carbocyclic 2'-deoxyguanosine in HSV-TK-expressing human tumor cells.

Human gene therapy, 2002, Mar-01, Volume: 13, Issue:4

Ganciclovir (GCV) is widely used as a prodrug for selective activation in tumor cells expressing herpes simplex virus thymidine kinase (HSV-TK) because of its ability to induce multi-log cytotoxicity to HSV-TK-expressing as well as nonexpressing bystander cells. We now report that another substrate for HSV-TK, D-carbocyclic 2'-deoxyguanosine (CdG), induces multi-log cytotoxicity in HSV-TK-expressing and bystander cells at concentrations

Topics: Antiviral Agents; Cell Death; Colonic Neoplasms; Deoxyguanosine; Enzyme Activation; Ganciclovir; Gene Transfer Techniques; Glioblastoma; Prodrugs; Simplexvirus; Thymidine Kinase; Tumor Cells, Cultured; Viral Proteins

2002