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alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid and Glioblastoma

alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid has been researched along with Glioblastoma in 3 studies

alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid: An IBOTENIC ACID homolog and glutamate agonist. The compound is the defining agonist for the AMPA subtype of glutamate receptors (RECEPTORS, AMPA). It has been used as a radionuclide imaging agent but is more commonly used as an experimental tool in cell biological studies.

Glioblastoma: A malignant form of astrocytoma histologically characterized by pleomorphism of cells, nuclear atypia, microhemorrhage, and necrosis. They may arise in any region of the central nervous system, with a predilection for the cerebral hemispheres, basal ganglia, and commissural pathways. Clinical presentation most frequently occurs in the fifth or sixth decade of life with focal neurologic signs or seizures.

Research Excerpts

ExcerptRelevanceReference
"The aim of the present study was to investigate the impacts of glyphosate herbicide on the survival and proliferation of glioblastoma cells and to explore the molecular mechanisms underlying such effects."8.31Glyphosate-induced glioblastoma cell proliferation: Unraveling the interplay of oxidative, inflammatory, proliferative, and survival signaling pathways. ( Bianco, CD; Dos Santos, DC; Kviecisnki, MR; Ourique, F; Pedrosa, RC; Zamoner, A, 2023)
"The aim of the present study was to investigate the impacts of glyphosate herbicide on the survival and proliferation of glioblastoma cells and to explore the molecular mechanisms underlying such effects."4.31Glyphosate-induced glioblastoma cell proliferation: Unraveling the interplay of oxidative, inflammatory, proliferative, and survival signaling pathways. ( Bianco, CD; Dos Santos, DC; Kviecisnki, MR; Ourique, F; Pedrosa, RC; Zamoner, A, 2023)
"Glioblastoma multiforme is the most undifferentiated type of brain tumor, and its prognosis is extremely poor."1.31Blockage of Ca(2+)-permeable AMPA receptors suppresses migration and induces apoptosis in human glioblastoma cells. ( Hagimura, N; Ishiuchi, S; Kurihara, H; Miwa, A; Nakazato, Y; Okado, H; Ozawa, S; Sasaki, T; Tamura, M; Tsuzuki, K; Yamada, N; Yoshida, Y, 2002)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (33.33)29.6817
2010's1 (33.33)24.3611
2020's1 (33.33)2.80

Authors

AuthorsStudies
Bianco, CD1
Ourique, F1
Dos Santos, DC1
Pedrosa, RC1
Kviecisnki, MR1
Zamoner, A1
Nandakumar, DN1
Ramaswamy, P1
Prasad, C1
Srinivas, D1
Goswami, K1
Ishiuchi, S1
Tsuzuki, K1
Yoshida, Y1
Yamada, N1
Hagimura, N1
Okado, H1
Miwa, A1
Kurihara, H1
Nakazato, Y1
Tamura, M1
Sasaki, T1
Ozawa, S1

Other Studies

3 other studies available for alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid and Glioblastoma

ArticleYear
Glyphosate-induced glioblastoma cell proliferation: Unraveling the interplay of oxidative, inflammatory, proliferative, and survival signaling pathways.
    Environmental pollution (Barking, Essex : 1987), 2023, Dec-01, Volume: 338

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Cell Proliferation; Glioblastoma; Glyphosa

2023
Glioblastoma invasion and NMDA receptors: A novel prospect.
    Physiology international, 2019, Sep-01, Volume: 106, Issue:3

    Topics: alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Cell Line, Tumor; Cell Movement; Dizocilpi

2019
Blockage of Ca(2+)-permeable AMPA receptors suppresses migration and induces apoptosis in human glioblastoma cells.
    Nature medicine, 2002, Volume: 8, Issue:9

    Topics: Adenoviridae; alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid; Animals; Apoptosis; Brain Ne

2002