Page last updated: 2024-11-08

cantharidin and Glioblastoma

cantharidin has been researched along with Glioblastoma in 3 studies

Cantharidin: A toxic compound, isolated from the Spanish fly or blistering beetle (Lytta (Cantharis) vesicatoria) and other insects. It is a potent and specific inhibitor of protein phosphatases 1 (PP1) and 2A (PP2A). This compound can produce severe skin inflammation, and is extremely toxic if ingested orally.
cantharidin : A monoterpenoid with an epoxy-bridged cyclic dicarboxylic anhydride structure secreted by many species of blister beetle, and most notably by the Spanish fly, Lytta vesicatoria. Natural toxin inhibitor of protein phosphatases 1 and 2A.

Glioblastoma: A malignant form of astrocytoma histologically characterized by pleomorphism of cells, nuclear atypia, microhemorrhage, and necrosis. They may arise in any region of the central nervous system, with a predilection for the cerebral hemispheres, basal ganglia, and commissural pathways. Clinical presentation most frequently occurs in the fifth or sixth decade of life with focal neurologic signs or seizures.

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (33.33)29.6817
2010's1 (33.33)24.3611
2020's1 (33.33)2.80

Authors

AuthorsStudies
Zhang, L1
Yu, J1
Pan, H1
Hu, P1
Hao, Y1
Cai, W1
Zhu, H1
Yu, AD1
Xie, X1
Ma, D1
Yuan, J1
Wang, CH2
Wu, HC2
Hsu, CW2
Chang, YW2
Ko, CY2
Hsu, TI2
Chuang, JY2
Tseng, TH2
Wang, SM2
Pitre, A1
Davis, N1
Paul, M1
Orr, AW1
Skalli, O1

Other Studies

3 other studies available for cantharidin and Glioblastoma

ArticleYear
Small molecule regulators of autophagy identified by an image-based high-throughput screen.
    Proceedings of the National Academy of Sciences of the United States of America, 2007, Nov-27, Volume: 104, Issue:48

    Topics: Autophagy; Calcium Channel Blockers; Cell Line, Tumor; Drug Evaluation, Preclinical; Fluspirilene; G

2007
Inhibition of MZF1/c-MYC Axis by Cantharidin Impairs Cell Proliferation in Glioblastoma.
    International journal of molecular sciences, 2022, Nov-25, Volume: 23, Issue:23

    Topics: Cantharidin; Cell Line, Tumor; Cell Proliferation; Gene Expression Regulation, Neoplastic; Glioblast

2022
Inhibition of MZF1/c-MYC Axis by Cantharidin Impairs Cell Proliferation in Glioblastoma.
    International journal of molecular sciences, 2022, Nov-25, Volume: 23, Issue:23

    Topics: Cantharidin; Cell Line, Tumor; Cell Proliferation; Gene Expression Regulation, Neoplastic; Glioblast

2022
Inhibition of MZF1/c-MYC Axis by Cantharidin Impairs Cell Proliferation in Glioblastoma.
    International journal of molecular sciences, 2022, Nov-25, Volume: 23, Issue:23

    Topics: Cantharidin; Cell Line, Tumor; Cell Proliferation; Gene Expression Regulation, Neoplastic; Glioblast

2022
Inhibition of MZF1/c-MYC Axis by Cantharidin Impairs Cell Proliferation in Glioblastoma.
    International journal of molecular sciences, 2022, Nov-25, Volume: 23, Issue:23

    Topics: Cantharidin; Cell Line, Tumor; Cell Proliferation; Gene Expression Regulation, Neoplastic; Glioblast

2022
Synemin promotes AKT-dependent glioblastoma cell proliferation by antagonizing PP2A.
    Molecular biology of the cell, 2012, Volume: 23, Issue:7

    Topics: Base Sequence; Cantharidin; Cell Line, Tumor; Cell Proliferation; Cyclin-Dependent Kinase Inhibitor

2012