Condition | Indicated | Relationship Strength | Studies | Trials |
ALS - Amyotrophic Lateral Sclerosis [description not available] | 0 | 2.61 | 2 | 0 |
Amyotrophic Lateral Sclerosis A degenerative disorder affecting upper MOTOR NEURONS in the brain and lower motor neurons in the brain stem and SPINAL CORD. Disease onset is usually after the age of 50 and the process is usually fatal within 3 to 6 years. Clinical manifestations include progressive weakness, atrophy, FASCICULATION, hyperreflexia, DYSARTHRIA, dysphagia, and eventual paralysis of respiratory function. Pathologic features include the replacement of motor neurons with fibrous ASTROCYTES and atrophy of anterior SPINAL NERVE ROOTS and corticospinal tracts. (From Adams et al., Principles of Neurology, 6th ed, pp1089-94) | 0 | 2.61 | 2 | 0 |
Degenerative Diseases, Central Nervous System [description not available] | 0 | 2.21 | 1 | 0 |
Neurodegenerative Diseases Hereditary and sporadic conditions which are characterized by progressive nervous system dysfunction. These disorders are often associated with atrophy of the affected central or peripheral nervous system structures. | 0 | 2.21 | 1 | 0 |
Kahler Disease [description not available] | 0 | 3 | 1 | 0 |
Multiple Myeloma A malignancy of mature PLASMA CELLS engaging in monoclonal immunoglobulin production. It is characterized by hyperglobulinemia, excess Bence-Jones proteins (free monoclonal IMMUNOGLOBULIN LIGHT CHAINS) in the urine, skeletal destruction, bone pain, and fractures. Other features include ANEMIA; HYPERCALCEMIA; and RENAL INSUFFICIENCY. | 0 | 8 | 1 | 0 |
Benign Neoplasms, Brain [description not available] | 0 | 2.11 | 1 | 0 |
Astrocytoma, Grade IV [description not available] | 0 | 2.11 | 1 | 0 |
Brain Neoplasms Neoplasms of the intracranial components of the central nervous system, including the cerebral hemispheres, basal ganglia, hypothalamus, thalamus, brain stem, and cerebellum. Brain neoplasms are subdivided into primary (originating from brain tissue) and secondary (i.e., metastatic) forms. Primary neoplasms are subdivided into benign and malignant forms. In general, brain tumors may also be classified by age of onset, histologic type, or presenting location in the brain. | 0 | 2.11 | 1 | 0 |
Glioblastoma A malignant form of astrocytoma histologically characterized by pleomorphism of cells, nuclear atypia, microhemorrhage, and necrosis. They may arise in any region of the central nervous system, with a predilection for the cerebral hemispheres, basal ganglia, and commissural pathways. Clinical presentation most frequently occurs in the fifth or sixth decade of life with focal neurologic signs or seizures. | 0 | 2.11 | 1 | 0 |
Diffuse Mixed Small and Large Cell Lymphoma [description not available] | 0 | 3.91 | 2 | 1 |
Lymphoma, Non-Hodgkin Any of a group of malignant tumors of lymphoid tissue that differ from HODGKIN DISEASE, being more heterogeneous with respect to malignant cell lineage, clinical course, prognosis, and therapy. The only common feature among these tumors is the absence of giant REED-STERNBERG CELLS, a characteristic of Hodgkin's disease. | 0 | 3.91 | 2 | 1 |
Disease Exacerbation [description not available] | 0 | 2.11 | 1 | 0 |
Disease Models, Animal Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases. | 0 | 2.11 | 1 | 0 |
Allergic Encephalomyelitis [description not available] | 0 | 2.11 | 1 | 0 |
Malignant Mesothelioma [description not available] | 0 | 3.03 | 1 | 0 |
Cancer of Lung [description not available] | 0 | 3.03 | 1 | 0 |
Peritoneal Carcinomatosis [description not available] | 0 | 3.03 | 1 | 0 |
Lung Neoplasms Tumors or cancer of the LUNG. | 0 | 3.03 | 1 | 0 |
Mesothelioma A tumor derived from mesothelial tissue (peritoneum, pleura, pericardium). It appears as broad sheets of cells, with some regions containing spindle-shaped, sarcoma-like cells and other regions showing adenomatous patterns. Pleural mesotheliomas have been linked to exposure to asbestos. (Dorland, 27th ed) | 0 | 3.03 | 1 | 0 |
Peritoneal Neoplasms Tumors or cancer of the PERITONEUM. | 0 | 3.03 | 1 | 0 |
Granulocytic Leukemia [description not available] | 0 | 2.07 | 1 | 0 |
Acute Disease Disease having a short and relatively severe course. | 0 | 2.07 | 1 | 0 |
Leukemia, Myeloid Form of leukemia characterized by an uncontrolled proliferation of the myeloid lineage and their precursors (MYELOID PROGENITOR CELLS) in the bone marrow and other sites. | 0 | 2.07 | 1 | 0 |