imidazole has been researched along with Glioblastoma in 1 studies
imidazole: RN given refers to parent cpd
1H-imidazole : An imidazole tautomer which has the migrating hydrogen at position 1.
Glioblastoma: A malignant form of astrocytoma histologically characterized by pleomorphism of cells, nuclear atypia, microhemorrhage, and necrosis. They may arise in any region of the central nervous system, with a predilection for the cerebral hemispheres, basal ganglia, and commissural pathways. Clinical presentation most frequently occurs in the fifth or sixth decade of life with focal neurologic signs or seizures.
| Excerpt | Relevance | Reference |
|---|---|---|
| " These new molecules displayed cytotoxic activities towards human glioblastoma cell lines, including the U251-MG cells that are highly resistant to the conventional chemotherapeutic agent Temozolomide." | 7.91 | Chemical modifications of imidazole-containing alkoxyamines increase C-ON bond homolysis rate: Effects on their cytotoxic properties in glioblastoma cells. ( Audran, G; Braguer, D; Brémond, P; Buric, D; Carré, M; Chacon, C; Marque, SRA; Yamasaki, T, 2019) |
| " These new molecules displayed cytotoxic activities towards human glioblastoma cell lines, including the U251-MG cells that are highly resistant to the conventional chemotherapeutic agent Temozolomide." | 3.91 | Chemical modifications of imidazole-containing alkoxyamines increase C-ON bond homolysis rate: Effects on their cytotoxic properties in glioblastoma cells. ( Audran, G; Braguer, D; Brémond, P; Buric, D; Carré, M; Chacon, C; Marque, SRA; Yamasaki, T, 2019) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Yamasaki, T | 1 |
| Buric, D | 1 |
| Chacon, C | 1 |
| Audran, G | 1 |
| Braguer, D | 1 |
| Marque, SRA | 1 |
| Carré, M | 1 |
| Brémond, P | 1 |
1 other study available for imidazole and Glioblastoma
| Article | Year |
|---|---|
Chemical modifications of imidazole-containing alkoxyamines increase C-ON bond homolysis rate: Effects on their cytotoxic properties in glioblastoma cells.
Topics: Amines; Antineoplastic Agents; Carbon; Cell Line, Tumor; Cell Survival; Glioblastoma; Half-Life; Hum | 2019 |