nitidine has been researched along with Glioblastoma in 3 studies
nitidine: RN given refers to parent cpd; synonym NSC 146397 refers to chloride; structure
Glioblastoma: A malignant form of astrocytoma histologically characterized by pleomorphism of cells, nuclear atypia, microhemorrhage, and necrosis. They may arise in any region of the central nervous system, with a predilection for the cerebral hemispheres, basal ganglia, and commissural pathways. Clinical presentation most frequently occurs in the fifth or sixth decade of life with focal neurologic signs or seizures.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Glioblastoma is the most aggressive and common intracranial malignant tumor, and the prognosis is still poor after various treatments." | 5.62 | Nitidine chloride suppresses epithelial-mesenchymal transition and stem cell-like properties in glioblastoma by regulating JAK2/STAT3 signaling. ( Guo, Y; Jia, M; Song, Y; Sun, Y; Wang, Y; Yu, P; Zhao, L, 2021) |
| "Glioblastoma is the most aggressive and common intracranial malignant tumor, and the prognosis is still poor after various treatments." | 1.62 | Nitidine chloride suppresses epithelial-mesenchymal transition and stem cell-like properties in glioblastoma by regulating JAK2/STAT3 signaling. ( Guo, Y; Jia, M; Song, Y; Sun, Y; Wang, Y; Yu, P; Zhao, L, 2021) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 1 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Jia, M | 1 |
| Wang, Y | 1 |
| Guo, Y | 1 |
| Yu, P | 1 |
| Sun, Y | 1 |
| Song, Y | 1 |
| Zhao, L | 1 |
| Deshpande, RP | 1 |
| Babu, PP | 1 |
| Liu, M | 1 |
| Wang, J | 2 |
| Qi, Q | 1 |
| Huang, B | 1 |
| Chen, A | 1 |
| Li, X | 1 |
3 other studies available for nitidine and Glioblastoma
| Article | Year |
|---|---|
Nitidine chloride suppresses epithelial-mesenchymal transition and stem cell-like properties in glioblastoma by regulating JAK2/STAT3 signaling.
Topics: Apoptosis; Benzophenanthridines; Brain Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferatio | 2021 |
pDok2, caspase 3 dependent glioma cell growth arrest by nitidine chloride.
Topics: Adaptor Proteins, Signal Transducing; Animals; Antineoplastic Agents; Benzophenanthridines; Brain Ne | 2018 |
Nitidine chloride inhibits the malignant behavior of human glioblastoma cells by targeting the PI3K/AKT/mTOR signaling pathway.
Topics: Animals; Apoptosis; Benzophenanthridines; Cell Line, Tumor; Cell Proliferation; Gene Expression Regu | 2016 |