hycanthone has been researched along with Glioblastoma in 1 studies
Hycanthone: Potentially toxic, but effective antischistosomal agent, it is a metabolite of LUCANTHONE.
hycanthone : A thioxanthen-9-one compound having a hydroxymethyl substituent at the 1-position and a 2-[(diethylamino)ethyl]amino substituent at the 4-position. It was formerly used (particularly as the monomethanesulfonic acid salt) as a schistosomicide for individual or mass treatement of infection with Schistosoma haematobium and S. mansoni, but due to its toxicity and concern about possible carcinogenicity, it has been replaced by other drugs such as praziquantel.
Glioblastoma: A malignant form of astrocytoma histologically characterized by pleomorphism of cells, nuclear atypia, microhemorrhage, and necrosis. They may arise in any region of the central nervous system, with a predilection for the cerebral hemispheres, basal ganglia, and commissural pathways. Clinical presentation most frequently occurs in the fifth or sixth decade of life with focal neurologic signs or seizures.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Naidu, MD | 1 |
| Agarwal, R | 1 |
| Pena, LA | 1 |
| Cunha, L | 1 |
| Mezei, M | 1 |
| Shen, M | 1 |
| Wilson, DM | 1 |
| Liu, Y | 1 |
| Sanchez, Z | 1 |
| Chaudhary, P | 1 |
| Wilson, SH | 1 |
| Waring, MJ | 1 |
1 other study available for hycanthone and Glioblastoma
| Article | Year |
|---|---|
Lucanthone and its derivative hycanthone inhibit apurinic endonuclease-1 (APE1) by direct protein binding.
Topics: Cell Line, Tumor; Circular Dichroism; DNA; DNA-(Apurinic or Apyrimidinic Site) Lyase; Glioblastoma; | 2011 |