Page last updated: 2024-12-11

kla peptide

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

KLA peptide: a synthetic amphipathic peptide that disrupts mitochondrial membranes when internalized; has antineoplastic activity [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID9855364
CHEMBL ID414487
MeSH IDM0529454

Synonyms (4)

Synonym
CHEMBL414487
kla peptide
CS-0881798
HY-P5345
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Bioassays (5)

Assay IDTitleYearJournalArticle
AID70092Compound was evaluated for antibacterial activity against Escherichia coli1996Journal of medicinal chemistry, Aug-02, Volume: 39, Issue:16
De novo antimicrobial peptides with low mammalian cell toxicity.
AID207641Compound was evaluated for antibacterial activity against Staphylococcus aureus1996Journal of medicinal chemistry, Aug-02, Volume: 39, Issue:16
De novo antimicrobial peptides with low mammalian cell toxicity.
AID91128Compound was measured for sublethal concentrations (uM) in Human erythrocytes1996Journal of medicinal chemistry, Aug-02, Volume: 39, Issue:16
De novo antimicrobial peptides with low mammalian cell toxicity.
AID164409Compound was evaluated for antibacterial activity against Pseudomonas aeruginosa1996Journal of medicinal chemistry, Aug-02, Volume: 39, Issue:16
De novo antimicrobial peptides with low mammalian cell toxicity.
AID140051Compound was tested for sublethal concentrations in 3T3 mouse fibroblast lysis.1996Journal of medicinal chemistry, Aug-02, Volume: 39, Issue:16
De novo antimicrobial peptides with low mammalian cell toxicity.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (34)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's1 (2.94)18.2507
2000's2 (5.88)29.6817
2010's28 (82.35)24.3611
2020's3 (8.82)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 21.31

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index21.31 (24.57)
Research Supply Index3.61 (2.92)
Research Growth Index5.62 (4.65)
Search Engine Demand Index18.60 (26.88)
Search Engine Supply Index2.00 (0.95)

This Compound (21.31)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other36 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]