acetylcysteine and Glioblastoma

acetylcysteine has been researched along with Glioblastoma in 24 studies

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (12.50)18.2507
2000's4 (16.67)29.6817
2010's15 (62.50)24.3611
2020's2 (8.33)2.80

Authors

AuthorsStudies
Chio, LM; Hsu, SS; Liang, WZ; Lin, YS1
Fang, F; Ji, Y; Li, H; Lu, Y; Qiu, P; Tang, H; Zhang, S1
da Silva, LCS; Dafre, AL; de Bem, AF; de Oliveira, KA; de Souza, LF; Farina, M; Nedel, CB; Schmitz, AE; Tasca, CI1
Hsu, SS; Jan, CR; Liang, WZ1
Li, F; Li, W; Song, D; Zhu, Y1
Cao, X; Chen, XZ; Deng, J; Hou, GQ; Li, SSC; Liu, AD; Ren, K; Wu, YS; Zhang, X1
Carra, E; Castagnola, P; Daga, A; Dono, M; Giaretti, W; Longo, L; Monteghirfo, S; Monticone, M; Stigliani, S; Taherian, R; Zupo, S1
Chi, SG; Chung, YG; Kang, SH; Park, DH; Park, KJ; Yu, MO1
Carpinelli, G; Castigli, E; Conte, C; Degrassi, F; Di Bari, M; Fiore, M; Iorio, E; Ricordy, R; Sciaccaluga, M; Tata, AM; Tombolillo, V1
Burant, CF; Davis, M; Dresser, J; Feng, FY; Kachman, M; Lawrence, TS; Lyssiotis, CA; Morgan, MA; Parsels, JD; Speers, C; Wahl, DR; Wernisch, S; Wilder-Romans, K; Zhao, L; Zhao, SG1
Barbarite, E; Gersey, ZC; Graham, RM; Komotar, RJ; Ohaeto, KC; Rodriguez, GA; Sanchez, A; Walters, WM1
Das, T; Finke, JH; Hilston, CM; Moon, C; Rayman, PA; Rini, BI; Sa, G; Tannenbaum, CS1
Dixit, D; Ghosh, S; Koul, N; Mishra, PK; Sen, E; Sharma, V1
Bergmann, M; Fassl, A; Gdynia, G; George, J; Kees, T; Keith, M; Kopitz, J; Roth, W; Schirmacher, P; Weber, AN; Wiestler, OD; Zentgraf, HW1
Castigli, E; Coaccioli, S; Corazzi, L; Davidescu, M; Macchioni, L; Marchetti, C; Migliorati, G; Roberti, R; Sciaccaluga, M1
Boumendjel, A; Boutonnat, J; Champelovier, P; Curri, V; Duchamp, E; Mininno, M; Nicolle, E1
Capasso, A; D'Acunto, CW; Festa, M; Masullo, M; Piacente, S; Pizza, C; Rossi, AG1
Cha, JH; Cha, SH; Cho, WH; Choi, CH; Choi, YJ1
Gao, H; Gao, R; Khan, M; Li, T; Ma, T; Rasul, A; Wang, N; Yi, F1
Broaddus, WC; Dent, P; Fisher, PB; Gopalkrishnan, RV; Grant, S; Lebedeva, IV; Lister, A; McKinstry, R; Mitchell, C; Qiao, L; Ramakrishnan, V; Sarkar, D; Sigmon, C; Su, ZZ; Yacoub, A1
Broaddus, WC; Curiel, DT; Dent, P; Fisher, PB; Gopalkrishnan, RV; Grant, S; Gupta, P; Hong, Y; James, CD; Lebedeva, IV; Mahasreshti, PJ; Mitchell, C; Rosenfeld, MR; Sauane, M; Su, ZZ; Yacoub, A1
Alvarez-Sala, R; Caballero, P; García Río, F; Pino, JM; Prados, C; Villamor, J1
Hirota, N; Iida, M; Kuribayashi, N; Matsumoto, K; Sakagami, H; Sunaga, S; Takeda, M1
Iida, T; Iwanaga, M; Kondo, T; Matsuo, T; Mori, K; Shibata, S; Urata, Y; Yasunaga, A1

Other Studies

24 other study(ies) available for acetylcysteine and Glioblastoma

ArticleYear
Evaluation of the mycotoxin patulin on cytotoxicity and oxidative stress in human glioblastoma cells and investigation of protective effect of the antioxidant N-acetylcysteine (NAC).
    Toxicon : official journal of the International Society on Toxinology, 2023, Jan-01, Volume: 221

    Topics: Acetylcysteine; Antioxidants; Glioblastoma; Humans; Oxidative Stress; Patulin; Reactive Oxygen Species

2023
A steroidal saponin form Paris vietnamensis (Takht.) reverses temozolomide resistance in glioblastoma cells via inducing apoptosis through ROS/PI3K/Akt pathway.
    Bioscience trends, 2020, May-21, Volume: 14, Issue:2

    Topics: Acetylcysteine; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Drug Resistance, Neoplasm; Free Radical Scavengers; Glioblastoma; Humans; Melanthiaceae; Phosphatidylinositol 3-Kinases; Reactive Oxygen Species; Rhizome; Saponins; Signal Transduction; Temozolomide

2020
Inhibition of reductase systems by 2-AAPA modulates peroxiredoxin oxidation and mitochondrial function in A172 glioblastoma cells.
    Toxicology in vitro : an international journal published in association with BIBRA, 2017, Volume: 42

    Topics: Acetylcysteine; Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Glioblastoma; Glutathione Reductase; Humans; Hydrogen Peroxide; Mitochondria; Peroxiredoxins; Thiocarbamates; Thioredoxin-Disulfide Reductase

2017
Evaluation of cytotoxicity of propofol and its related mechanism in glioblastoma cells and astrocytes.
    Environmental toxicology, 2017, Volume: 32, Issue:12

    Topics: Acetylcysteine; Amino Acid Chloromethyl Ketones; Animals; Antineoplastic Agents; Antioxidants; Apoptosis; Astrocytes; Caspase 3; Caspase 9; Caspase Inhibitors; Cell Cycle; Cell Cycle Checkpoints; Cell Line, Tumor; Glioblastoma; Humans; Propofol; Rats; Reactive Oxygen Species

2017
RETRACTED: Physcion 8-O-β-glucopyranosideregulates cell cycle, apoptosis, and invasion in glioblastoma cells through modulating Skp2.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2017, Volume: 95

    Topics: Acetylcysteine; Adenylate Kinase; Antineoplastic Agents; Apoptosis; Brain Neoplasms; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Emodin; Glioblastoma; Glucosides; Humans; Reactive Oxygen Species; S-Phase Kinase-Associated Proteins; TOR Serine-Threonine Kinases

2017
N-acetylcysteine decreases malignant characteristics of glioblastoma cells by inhibiting Notch2 signaling.
    Journal of experimental & clinical cancer research : CR, 2019, Jan-03, Volume: 38, Issue:1

    Topics: Acetylcysteine; Animals; Antiviral Agents; Disease Models, Animal; Glioblastoma; Humans; Mice; Receptor, Notch2; Signal Transduction; Transfection

2019
NAC, tiron and trolox impair survival of cell cultures containing glioblastoma tumorigenic initiating cells by inhibition of cell cycle progression.
    PloS one, 2014, Volume: 9, Issue:2

    Topics: 1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt; Acetylcysteine; Astrocytes; Cell Cycle; Cell Cycle Proteins; Cell Line; Cell Proliferation; Cell Survival; Chromans; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Glioblastoma; Humans; Reactive Oxygen Species; Signal Transduction; Tumor Cells, Cultured

2014
Reactive oxygen species production has a critical role in hypoxia-induced Stat3 activation and angiogenesis in human glioblastoma.
    Journal of neuro-oncology, 2015, Volume: 125, Issue:1

    Topics: Acetylcysteine; Brain Neoplasms; Cell Line, Tumor; Enzyme Inhibitors; Free Radical Scavengers; Gene Expression Regulation, Neoplastic; Glioblastoma; Humans; Hypoxia; NADPH Oxidase 4; NADPH Oxidases; Neovascularization, Pathologic; Reactive Oxygen Species; RNA, Messenger; RNA, Small Interfering; Signal Transduction; STAT3 Transcription Factor; Vascular Endothelial Growth Factor A

2015
Cytotoxic and genotoxic effects mediated by M2 muscarinic receptor activation in human glioblastoma cells.
    Neurochemistry international, 2015, Volume: 90

    Topics: Acetylcysteine; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Glioblastoma; Humans; Muscarinic Agonists; Receptor, Muscarinic M2; Receptors, Muscarinic

2015
Glioblastoma Therapy Can Be Augmented by Targeting IDH1-Mediated NADPH Biosynthesis.
    Cancer research, 2017, 02-15, Volume: 77, Issue:4

    Topics: Acetylcysteine; Animals; Brain Neoplasms; Cell Line, Tumor; Glioblastoma; Humans; Isocitrate Dehydrogenase; Male; Mice; NADP; Radiation Tolerance; Xenograft Model Antitumor Assays

2017
Curcumin decreases malignant characteristics of glioblastoma stem cells via induction of reactive oxygen species.
    BMC cancer, 2017, 02-04, Volume: 17, Issue:1

    Topics: Acetylcysteine; Adult; Antineoplastic Agents; Cell Proliferation; Cell Survival; Curcumin; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Free Radical Scavengers; Glioblastoma; Humans; Inhibitor of Apoptosis Proteins; Inhibitory Concentration 50; Mitogen-Activated Protein Kinases; Neoplastic Stem Cells; Oxidative Stress; Reactive Oxygen Species; STAT3 Transcription Factor; Survivin; Tumor Cells, Cultured

2017
GD3, an overexpressed tumor-derived ganglioside, mediates the apoptosis of activated but not resting T cells.
    Cancer research, 2009, Apr-01, Volume: 69, Issue:7

    Topics: Acetylcysteine; Antioxidants; Apoptosis; Carcinoma, Renal Cell; Caspase 8; Caspase 9; Caspase Inhibitors; Cell Line, Tumor; Cell Membrane Permeability; Cytochromes c; Gangliosides; Glioblastoma; Humans; Jurkat Cells; Kidney Neoplasms; Lymphocyte Activation; Mitochondrial Membranes; Reactive Oxygen Species; T-Lymphocytes

2009
Manumycin inhibits STAT3, telomerase activity, and growth of glioma cells by elevating intracellular reactive oxygen species generation.
    Free radical biology & medicine, 2009, Aug-15, Volume: 47, Issue:4

    Topics: Acetylcysteine; Apoptosis; Caspase 3; Cell Cycle; Cell Growth Processes; Cell Line, Tumor; Farnesyltranstransferase; Gene Expression Regulation; Glioblastoma; Glioma; Humans; Oxidative Stress; Phosphorylation; Poly(ADP-ribose) Polymerases; Polyenes; Polyunsaturated Alkamides; Proto-Oncogene Proteins p21(ras); Reactive Oxygen Species; RNA, Small Interfering; STAT3 Transcription Factor; Superoxide Dismutase; Superoxide Dismutase-1; Telomerase; Thioredoxins

2009
Danger signaling protein HMGB1 induces a distinct form of cell death accompanied by formation of giant mitochondria.
    Cancer research, 2010, Nov-01, Volume: 70, Issue:21

    Topics: Acetylcysteine; Animals; Apoptosis; Astrocytes; Blotting, Western; Cell Line, Tumor; Cell Nucleus; Cell Proliferation; Electrophoresis, Gel, Two-Dimensional; Female; Fluorescent Antibody Technique; Free Radical Scavengers; Glioblastoma; HMGB1 Protein; Humans; JNK Mitogen-Activated Protein Kinases; Membrane Potential, Mitochondrial; Mice; Mice, Nude; Mitochondria; Mitochondrial Proteins; Necrosis; Proteome; Reactive Oxygen Species; Signal Transduction; Tumor Cells, Cultured

2010
Mitochondrial dysfunction and effect of antiglycolytic bromopyruvic acid in GL15 glioblastoma cells.
    Journal of bioenergetics and biomembranes, 2011, Volume: 43, Issue:5

    Topics: Acetylcysteine; Adenosine Triphosphate; Apoptosis; Cell Line, Tumor; Cytochromes c; Enzyme Inhibitors; Free Radical Scavengers; Glioblastoma; Glycolysis; Humans; Membrane Potential, Mitochondrial; Mitochondria; Mitochondrial Membranes; Oxidation-Reduction; Proteolysis; Pyruvates; Reactive Oxygen Species

2011
Cytotoxicity of chalcone derivatives towards glioblastoma.
    Anticancer research, 2011, Volume: 31, Issue:10

    Topics: Acetylcysteine; Apoptosis; Cell Death; Cell Line, Tumor; Cell Proliferation; Cell Survival; Chalcone; Drug Screening Assays, Antitumor; Glioblastoma; Humans; Rhodamines; Spheroids, Cellular; Structure-Activity Relationship

2011
Xanthohumol induces apoptosis in human malignant glioblastoma cells by increasing reactive oxygen species and activating MAPK pathways.
    Journal of natural products, 2011, Dec-27, Volume: 74, Issue:12

    Topics: Acetylcysteine; Antineoplastic Agents; Apoptosis; Caspase 3; Caspase 9; Cyclohexenes; Cytochromes c; Dose-Response Relationship, Drug; Flavonoids; Glioblastoma; Humans; Imidazoles; Italy; Mitogen-Activated Protein Kinases; Molecular Structure; Poly(ADP-ribose) Polymerases; Propiophenones; Pyridines; Reactive Oxygen Species; Terpenes

2011
Allicin inhibits cell growth and induces apoptosis in U87MG human glioblastoma cells through an ERK-dependent pathway.
    Oncology reports, 2012, Volume: 28, Issue:1

    Topics: Acetylcysteine; Antineoplastic Agents; Antioxidants; Apoptosis; bcl-2-Associated X Protein; Butadienes; Caspases; Catalase; Cell Line, Tumor; Cell Proliferation; Cell Shape; Cell Survival; Disulfides; Extracellular Signal-Regulated MAP Kinases; Glioblastoma; Humans; Imidazoles; MAP Kinase Signaling System; Nitriles; Phosphorylation; Proto-Oncogene Proteins c-bcl-2; Pyridines; Sulfinic Acids

2012
Alantolactone induces apoptosis in glioblastoma cells via GSH depletion, ROS generation, and mitochondrial dysfunction.
    IUBMB life, 2012, Volume: 64, Issue:9

    Topics: Acetylcysteine; Active Transport, Cell Nucleus; Animals; Antineoplastic Agents; Antioxidants; Apoptosis; Blood-Brain Barrier; Brain Neoplasms; Cardiolipins; Cell Line, Tumor; Cell Proliferation; Cell Survival; Glioblastoma; Glutamate-Cysteine Ligase; Glutathione; Glutathione Transferase; Humans; Kidney; Lactones; Liver; Membrane Potential, Mitochondrial; Mice; Mitochondria; NF-kappa B; Oxidation-Reduction; Reactive Oxygen Species; Sesquiterpenes, Eudesmane; Tissue Distribution; Xenograft Model Antitumor Assays

2012
Melanoma differentiation-associated 7 (interleukin 24) inhibits growth and enhances radiosensitivity of glioma cells in vitro and in vivo.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2003, Aug-15, Volume: 9, Issue:9

    Topics: Acetylcysteine; Adenoviridae; Animals; Astrocytes; bcl-2-Associated X Protein; bcl-X Protein; Blotting, Western; Brain Neoplasms; Cell Division; Cell Line; Cell Line, Tumor; Cell Survival; Cells, Cultured; DNA Fragmentation; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Down-Regulation; Gene Transfer Techniques; Genes, Tumor Suppressor; Glioblastoma; Glioma; Glutathione Transferase; Humans; Interleukins; Necrosis; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Radiation-Sensitizing Agents; Rats; Rats, Inbred F344; Tetrazolium Salts; Thiazoles; Time Factors

2003
MDA-7 regulates cell growth and radiosensitivity in vitro of primary (non-established) human glioma cells.
    Cancer biology & therapy, 2004, Volume: 3, Issue:8

    Topics: Acetylcysteine; Adenoviridae; Adjuvants, Immunologic; Apoptosis; Astrocytes; bcl-2-Associated X Protein; bcl-X Protein; Brain Neoplasms; Caspase 8; Caspase 9; Caspase Inhibitors; Caspases; Cell Line, Tumor; Cell Proliferation; Colony-Forming Units Assay; Enzyme Activation; Enzyme Inhibitors; ErbB Receptors; Genes, erbB-1; Genes, Tumor Suppressor; Glioblastoma; Humans; Interleukins; JNK Mitogen-Activated Protein Kinases; MAP Kinase Kinase 4; Mitogen-Activated Protein Kinase Kinases; Phosphoric Monoester Hydrolases; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-bcl-2; PTEN Phosphohydrolase; Radiation Tolerance; Radiation-Sensitizing Agents; Tumor Cells, Cultured; Tumor Suppressor Protein p53; Tumor Suppressor Proteins

2004
Six cases of pulmonary alveolar proteinosis: presentation of unusual associations.
    Monaldi archives for chest disease = Archivio Monaldi per le malattie del torace, 1995, Volume: 50, Issue:1

    Topics: Acetylcysteine; Adult; Ambroxol; Biopsy; Brain Neoplasms; Bronchoalveolar Lavage Fluid; Child; Fanconi Syndrome; Female; Glioblastoma; Heart Septal Defects; Humans; Infant, Newborn; Lung; Male; Middle Aged; Oxygen Inhalation Therapy; Pulmonary Alveolar Proteinosis; Respiratory Function Tests; Tuberculosis, Pulmonary

1995
Effect of glutathione-modulating compounds on hydrogen-peroxide-induced cytotoxicity in human glioblastoma and glioma cell lines.
    Journal of cancer research and clinical oncology, 1997, Volume: 123, Issue:11-12

    Topics: Acetylcysteine; Buthionine Sulfoximine; Cell Survival; Dose-Response Relationship, Drug; Enzyme Inhibitors; Free Radical Scavengers; Glioblastoma; Glioma; Glutathione; Humans; Hydrogen Peroxide; Tumor Cells, Cultured

1997
Nuclear factor kappa B dependent induction of gamma glutamylcysteine synthetase by ionizing radiation in T98G human glioblastoma cells.
    Free radical biology & medicine, 1998, Volume: 24, Issue:7-8

    Topics: Acetylcysteine; Antioxidants; Base Sequence; Binding Sites; Buthionine Sulfoximine; DNA Damage; DNA, Neoplasm; Enzyme Induction; Glioblastoma; Glutamate-Cysteine Ligase; Glutathione; Humans; Luciferases; NF-kappa B; Oxidative Stress; Promoter Regions, Genetic; Radiation Tolerance; RNA, Messenger; RNA, Neoplasm; Transfection; Tumor Cells, Cultured

1998