meperidine has been researched along with Glioblastoma in 1 studies
Meperidine: A narcotic analgesic that can be used for the relief of most types of moderate to severe pain, including postoperative pain and the pain of labor. Prolonged use may lead to dependence of the morphine type; withdrawal symptoms appear more rapidly than with morphine and are of shorter duration.
pethidine : A piperidinecarboxylate ester that is piperidine which is substituted by a methyl group at position 1 and by phenyl and ethoxycarbonyl groups at position 4. It is an analgesic which is used for the treatment of moderate to severe pain, including postoperative pain and labour pain.
Glioblastoma: A malignant form of astrocytoma histologically characterized by pleomorphism of cells, nuclear atypia, microhemorrhage, and necrosis. They may arise in any region of the central nervous system, with a predilection for the cerebral hemispheres, basal ganglia, and commissural pathways. Clinical presentation most frequently occurs in the fifth or sixth decade of life with focal neurologic signs or seizures.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Meperidine (pethidine) is a µ-opioid receptor (MOR) agonist widely used in the treatment of cancer pain." | 6.82 | A hypothetical proposal to employ meperidine and tamoxifen in treatment of glioblastoma. Role of P-glycoprotein, ceramide and metabolic pathways. ( Altinoz, MA; Hacker, E; Ozpinar, A, 2022) |
| "Meperidine (pethidine) is a µ-opioid receptor (MOR) agonist widely used in the treatment of cancer pain." | 2.82 | A hypothetical proposal to employ meperidine and tamoxifen in treatment of glioblastoma. Role of P-glycoprotein, ceramide and metabolic pathways. ( Altinoz, MA; Hacker, E; Ozpinar, A, 2022) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (100.00) | 2.80 |
| Authors | Studies |
|---|---|
| Altinoz, MA | 1 |
| Ozpinar, A | 2 |
| Hacker, E | 1 |
1 review available for meperidine and Glioblastoma
| Article | Year |
|---|---|
A hypothetical proposal to employ meperidine and tamoxifen in treatment of glioblastoma. Role of P-glycoprotein, ceramide and metabolic pathways.
Topics: Apoptosis; ATP Binding Cassette Transporter, Subfamily B, Member 1; Ceramides; Glioblastoma; Humans; | 2022 |