prazosin has been researched along with Glioblastoma in 2 studies
Prazosin: A selective adrenergic alpha-1 antagonist used in the treatment of HEART FAILURE; HYPERTENSION; PHEOCHROMOCYTOMA; RAYNAUD DISEASE; PROSTATIC HYPERTROPHY; and URINARY RETENTION.
prazosin : A member of the class of piperazines that is piperazine substituted by a furan-2-ylcarbonyl group and a 4-amino-6,7-dimethoxyquinazolin-2-yl group at positions 1 and 4 respectively.
Glioblastoma: A malignant form of astrocytoma histologically characterized by pleomorphism of cells, nuclear atypia, microhemorrhage, and necrosis. They may arise in any region of the central nervous system, with a predilection for the cerebral hemispheres, basal ganglia, and commissural pathways. Clinical presentation most frequently occurs in the fifth or sixth decade of life with focal neurologic signs or seizures.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Glioblastoma multiforme is an aggressive form of human astrocytoma, with poor prognosis due to multi-drug resistance to a number of anticancer drugs." | 1.40 | Characterization of a multiple endogenously expressed adenosine triphosphate-binding cassette transporters using nuclear and cellular membrane affinity chromatography columns. ( Habicht, KL; Khadeer, MA; Moaddel, R; Shimmo, R; Singh, NS; Wainer, IW, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Habicht, KL | 1 |
| Singh, NS | 1 |
| Khadeer, MA | 1 |
| Shimmo, R | 1 |
| Wainer, IW | 1 |
| Moaddel, R | 1 |
| Assad Kahn, S | 1 |
| Costa, SL | 1 |
| Gholamin, S | 1 |
| Nitta, RT | 1 |
| Dubois, LG | 1 |
| Fève, M | 1 |
| Zeniou, M | 1 |
| Coelho, PL | 1 |
| El-Habr, E | 1 |
| Cadusseau, J | 1 |
| Varlet, P | 1 |
| Mitra, SS | 1 |
| Devaux, B | 1 |
| Kilhoffer, MC | 1 |
| Cheshier, SH | 1 |
| Moura-Neto, V | 1 |
| Haiech, J | 1 |
| Junier, MP | 1 |
| Chneiweiss, H | 1 |
2 other studies available for prazosin and Glioblastoma
| Article | Year |
|---|---|
Characterization of a multiple endogenously expressed adenosine triphosphate-binding cassette transporters using nuclear and cellular membrane affinity chromatography columns.
Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily | 2014 |
The anti-hypertensive drug prazosin inhibits glioblastoma growth via the PKCδ-dependent inhibition of the AKT pathway.
Topics: Animals; Antihypertensive Agents; Antineoplastic Agents; Apoptosis; Cell Survival; Disease Models, A | 2016 |