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prazosin and Glioblastoma

prazosin has been researched along with Glioblastoma in 2 studies

Prazosin: A selective adrenergic alpha-1 antagonist used in the treatment of HEART FAILURE; HYPERTENSION; PHEOCHROMOCYTOMA; RAYNAUD DISEASE; PROSTATIC HYPERTROPHY; and URINARY RETENTION.
prazosin : A member of the class of piperazines that is piperazine substituted by a furan-2-ylcarbonyl group and a 4-amino-6,7-dimethoxyquinazolin-2-yl group at positions 1 and 4 respectively.

Glioblastoma: A malignant form of astrocytoma histologically characterized by pleomorphism of cells, nuclear atypia, microhemorrhage, and necrosis. They may arise in any region of the central nervous system, with a predilection for the cerebral hemispheres, basal ganglia, and commissural pathways. Clinical presentation most frequently occurs in the fifth or sixth decade of life with focal neurologic signs or seizures.

Research Excerpts

ExcerptRelevanceReference
"Glioblastoma multiforme is an aggressive form of human astrocytoma, with poor prognosis due to multi-drug resistance to a number of anticancer drugs."1.40Characterization of a multiple endogenously expressed adenosine triphosphate-binding cassette transporters using nuclear and cellular membrane affinity chromatography columns. ( Habicht, KL; Khadeer, MA; Moaddel, R; Shimmo, R; Singh, NS; Wainer, IW, 2014)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Habicht, KL1
Singh, NS1
Khadeer, MA1
Shimmo, R1
Wainer, IW1
Moaddel, R1
Assad Kahn, S1
Costa, SL1
Gholamin, S1
Nitta, RT1
Dubois, LG1
Fève, M1
Zeniou, M1
Coelho, PL1
El-Habr, E1
Cadusseau, J1
Varlet, P1
Mitra, SS1
Devaux, B1
Kilhoffer, MC1
Cheshier, SH1
Moura-Neto, V1
Haiech, J1
Junier, MP1
Chneiweiss, H1

Other Studies

2 other studies available for prazosin and Glioblastoma

ArticleYear
Characterization of a multiple endogenously expressed adenosine triphosphate-binding cassette transporters using nuclear and cellular membrane affinity chromatography columns.
    Journal of chromatography. A, 2014, Apr-25, Volume: 1339

    Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily

2014
The anti-hypertensive drug prazosin inhibits glioblastoma growth via the PKCδ-dependent inhibition of the AKT pathway.
    EMBO molecular medicine, 2016, Volume: 8, Issue:5

    Topics: Animals; Antihypertensive Agents; Antineoplastic Agents; Apoptosis; Cell Survival; Disease Models, A

2016