pentamidine has been researched along with Glioblastoma in 2 studies
Pentamidine: Antiprotozoal agent effective in trypanosomiasis, leishmaniasis, and some fungal infections; used in treatment of PNEUMOCYSTIS pneumonia in HIV-infected patients. It may cause diabetes mellitus, central nervous system damage, and other toxic effects.
pentamidine : A diether consisting of pentane-1,5-diol in which both hydroxyl hydrogens have been replaced by 4-amidinophenyl groups. A trypanocidal drug that is used for treatment of cutaneous leishmaniasis and Chagas disease.
Glioblastoma: A malignant form of astrocytoma histologically characterized by pleomorphism of cells, nuclear atypia, microhemorrhage, and necrosis. They may arise in any region of the central nervous system, with a predilection for the cerebral hemispheres, basal ganglia, and commissural pathways. Clinical presentation most frequently occurs in the fifth or sixth decade of life with focal neurologic signs or seizures.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Pentamidine treatment suppressed proliferation and stemness in glioma-initiating cell lines." | 5.91 | Therapeutic potential of pentamidine for glioma-initiating cells and glioma cells through multimodal antitumor effects. ( Hirai, N; Hirao, A; Ichinose, T; Jiapaer, S; Kinoshita, M; Kobayashi, M; Nakada, M; Sabit, H; Tamai, S; Tanaka, S, 2023) |
| "Pentamidine treatment suppressed proliferation and stemness in glioma-initiating cell lines." | 1.91 | Therapeutic potential of pentamidine for glioma-initiating cells and glioma cells through multimodal antitumor effects. ( Hirai, N; Hirao, A; Ichinose, T; Jiapaer, S; Kinoshita, M; Kobayashi, M; Nakada, M; Sabit, H; Tamai, S; Tanaka, S, 2023) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Tamai, S | 1 |
| Ichinose, T | 1 |
| Jiapaer, S | 1 |
| Hirai, N | 1 |
| Sabit, H | 1 |
| Tanaka, S | 1 |
| Kinoshita, M | 1 |
| Kobayashi, M | 1 |
| Hirao, A | 1 |
| Nakada, M | 1 |
| Thuringer, D | 1 |
| Chanteloup, G | 1 |
| Boucher, J | 1 |
| Pernet, N | 1 |
| Boudesco, C | 1 |
| Jego, G | 1 |
| Chatelier, A | 1 |
| Bois, P | 1 |
| Gobbo, J | 1 |
| Cronier, L | 1 |
| Solary, E | 1 |
| Garrido, C | 1 |
2 other studies available for pentamidine and Glioblastoma
| Article | Year |
|---|---|
Therapeutic potential of pentamidine for glioma-initiating cells and glioma cells through multimodal antitumor effects.
Topics: Animals; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Glioblastoma; Glioma; Hum | 2023 |
Modulation of the inwardly rectifying potassium channel Kir4.1 by the pro-invasive miR-5096 in glioblastoma cells.
Topics: Cell Movement; Cells, Cultured; Glioblastoma; Humans; MicroRNAs; Pentamidine; Potassium Channels, In | 2017 |