5,5-dimethyl-1-pyrroline-1-oxide has been researched along with Glioblastoma in 1 studies
5,5-dimethyl-1-pyrroline-1-oxide: do not confuse with DMPO (4',5'-dihydroxy-7-methoxy-4-phenyl-5,2'-oxidocoumarin)
5,5-dimethyl-1-pyrroline N-oxide : A member of the class of 1-pyrroline nitrones (1-pyrroline N-oxides) resulting from the formal N-oxidation of 5,5-dimethyl-1-pyrroline. Used as a spin trap for the study of radicals formed by enzymatic acetaldehyde oxidation.
Glioblastoma: A malignant form of astrocytoma histologically characterized by pleomorphism of cells, nuclear atypia, microhemorrhage, and necrosis. They may arise in any region of the central nervous system, with a predilection for the cerebral hemispheres, basal ganglia, and commissural pathways. Clinical presentation most frequently occurs in the fifth or sixth decade of life with focal neurologic signs or seizures.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Electron spin resonance (ESR) analyses were performed to clarify whether glioblastoma cells scavenge hydroxyl radicals (*OH) generated by x-ray irradiation." | 3.72 | Reduction of nitroxides and radioprotective ability in glioblastoma cells. ( Anzai, K; Moritake, T; Nose, T; Ozawa, T; Tsuboi, K, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Moritake, T | 1 |
| Tsuboi, K | 1 |
| Anzai, K | 1 |
| Ozawa, T | 1 |
| Nose, T | 1 |
1 other study available for 5,5-dimethyl-1-pyrroline-1-oxide and Glioblastoma
| Article | Year |
|---|---|
Reduction of nitroxides and radioprotective ability in glioblastoma cells.
Topics: Cell Line, Tumor; Cell Survival; Cyclic N-Oxides; Electron Spin Resonance Spectroscopy; Free Radical | 2003 |