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2-amino-5-phosphonovalerate and Glioblastoma

2-amino-5-phosphonovalerate has been researched along with Glioblastoma in 1 studies

2-Amino-5-phosphonovalerate: The D-enantiomer is a potent and specific antagonist of NMDA glutamate receptors (RECEPTORS, N-METHYL-D-ASPARTATE). The L form is inactive at NMDA receptors but may affect the AP4 (2-amino-4-phosphonobutyrate; APB) excitatory amino acid receptors.

Glioblastoma: A malignant form of astrocytoma histologically characterized by pleomorphism of cells, nuclear atypia, microhemorrhage, and necrosis. They may arise in any region of the central nervous system, with a predilection for the cerebral hemispheres, basal ganglia, and commissural pathways. Clinical presentation most frequently occurs in the fifth or sixth decade of life with focal neurologic signs or seizures.

Research Excerpts

ExcerptRelevanceReference
"Ketamine is a potent anti-depressive agent."1.46Ketamine upregulates eNOS expression in human astroglial A172 cells: Possible role in its antidepressive properties. ( Ashkenazi, S; Berent, E; Weizman, A; Yuhas, Y, 2017)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Yuhas, Y1
Ashkenazi, S1
Berent, E1
Weizman, A1

Other Studies

1 other study available for 2-amino-5-phosphonovalerate and Glioblastoma

ArticleYear
Ketamine upregulates eNOS expression in human astroglial A172 cells: Possible role in its antidepressive properties.
    Journal of neuroimmunology, 2017, 04-15, Volume: 305

    Topics: Astrocytes; Cell Line, Transformed; Dose-Response Relationship, Drug; Enzyme Inhibitors; Excitatory

2017