carbamazepine has been researched along with Glioblastoma in 6 studies
Carbamazepine: A dibenzazepine that acts as a sodium channel blocker. It is used as an anticonvulsant for the treatment of grand mal and psychomotor or focal SEIZURES. It may also be used in the management of BIPOLAR DISORDER, and has analgesic properties.
carbamazepine : A dibenzoazepine that is 5H-dibenzo[b,f]azepine carrying a carbamoyl substituent at the azepine nitrogen, used as an anticonvulsant.
Glioblastoma: A malignant form of astrocytoma histologically characterized by pleomorphism of cells, nuclear atypia, microhemorrhage, and necrosis. They may arise in any region of the central nervous system, with a predilection for the cerebral hemispheres, basal ganglia, and commissural pathways. Clinical presentation most frequently occurs in the fifth or sixth decade of life with focal neurologic signs or seizures.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Seizures are among the most common clinical signs in people with glioblastoma." | 3.01 | The complexities underlying epilepsy in people with glioblastoma. ( Cole, AJ; Dietrich, J; Sokolov, E, 2023) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (33.33) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 2 (33.33) | 24.3611 |
| 2020's | 1 (16.67) | 2.80 |
| Authors | Studies |
|---|---|
| Zmuda, F | 1 |
| Malviya, G | 1 |
| Blair, A | 1 |
| Boyd, M | 1 |
| Chalmers, AJ | 1 |
| Sutherland, A | 1 |
| Pimlott, SL | 1 |
| Sokolov, E | 1 |
| Dietrich, J | 1 |
| Cole, AJ | 1 |
| Guthrie, GD | 1 |
| Eljamel, S | 1 |
| Ducray, F | 1 |
| Colin, P | 1 |
| Cartalat-Carel, S | 1 |
| Pelissou-Guyotat, I | 1 |
| Mahla, K | 1 |
| Audra, P | 1 |
| Gaucherand, P | 1 |
| Honnorat, J | 1 |
| Trouillas, P | 1 |
| Stewart, JT | 1 |
| Ghosh, C | 1 |
| Lazarus, HM | 1 |
| Hewlett, JS | 1 |
| Creger, RJ | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Prospective Trial for Validation of the Role of Levetiracetam as a Sensitizer of Temozolomide in the Treatment of Newly Diagnosed Glioblastoma Patients[NCT02815410] | Phase 2 | 73 participants (Anticipated) | Interventional | 2016-07-31 | Not yet recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for carbamazepine and Glioblastoma
| Article | Year |
|---|---|
The complexities underlying epilepsy in people with glioblastoma.
Topics: Anticonvulsants; Carbamazepine; Epilepsies, Partial; Epilepsy; Epilepsy, Generalized; Glioblastoma; | 2023 |
Impact of particular antiepileptic drugs on the survival of patients with glioblastoma multiforme.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Brain Neoplasms; Carbamazepine; Cohort Studies; Female; Gl | 2013 |
1 trial available for carbamazepine and Glioblastoma
| Article | Year |
|---|---|
Fluctuation of serum phenytoin concentrations during autologous bone marrow transplant for primary central nervous system tumors.
Topics: Adult; Anticonvulsants; Astrocytoma; Bone Marrow Transplantation; Brain Neoplasms; Carbamazepine; Fe | 1992 |
3 other studies available for carbamazepine and Glioblastoma
| Article | Year |
|---|---|
Synthesis and Evaluation of a Radioiodinated Tracer with Specificity for Poly(ADP-ribose) Polymerase-1 (PARP-1) in Vivo.
Topics: Animals; Cell Line, Tumor; Enzyme Inhibitors; Glioblastoma; Humans; Iodine Radioisotopes; Mice; Mice | 2015 |
[Management of malignant gliomas diagnosed during pregnancy].
Topics: Abortion, Therapeutic; Adrenal Cortex Hormones; Adult; Algorithms; Anesthesia, General; Antineoplast | 2006 |
Treatment of coprophagia with carbamazepine.
Topics: Brain Neoplasms; Carbamazepine; Drug Therapy, Combination; Glioblastoma; Human Coprophagia; Humans; | 1995 |