Compounds > tetralol
Page last updated: 2024-12-05

tetralol

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

Tetralol is a synthetic compound with a tetralin ring structure and hydroxyl groups. It has been studied for its potential therapeutic applications, particularly as a beta-blocker and anti-inflammatory agent. Research suggests that tetralol may exhibit antioxidant and anti-proliferative properties. However, its clinical applications remain limited, and further research is required to fully understand its effects and potential benefits.'

tetralol: structure [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID10747
SCHEMBL ID291460
SCHEMBL ID13998125
MeSH IDM0071266

Synonyms (54)

Synonym
.beta.-tetralol
nsc-5669
1,3,4-tetrahydro-2-naphthol
tetralol
2-hydroxytetralin
wln: l66&tj hq
nsc5669
530-91-6
2-naphthalenol,2,3,4-tetrahydro-
2-naphthol,2,3,4-tetrahydro-
2-naphthalenol, 1,2,3,4-tetrahydro-
1,2,3,4-tetrahydro-2 naphthol
nsc44875
nsc-44875
1,2,3,4-tetrahydronaphthalen-2-ol
2-naphthol, 1,2,3,4-tetrahydro-
ai3-05563
nsc 44875
2-hydroxytetraline
tetrahydronaphthol-2
einecs 208-497-8
brn 2046968
ac-tetrahydro-beta-naphthol
hsdb 5679
2-tetralinol
beta-tetralol
1,2,3,4-tetrahydro-2-naphthol
AKOS005138106
1,2,3,4-tetrahydro-naphthalen-2-ol
EN300-69633
6ae2v413ji ,
unii-6ae2v413ji
3-06-00-02460 (beilstein handbook reference)
FT-0612640
tetralol [mi]
.beta.-tetralol [hsdb]
1,2,3,4-tetrahydro-2-naphthol, (+/-)-
2-hydroxy-1,2,3,4-tetrahydronaphthalene
ac-tetrahydro-.beta.-naphthol
2-tetralol
SCHEMBL291460
1,2,3,4-tetrahydro-2-napthol
1,2,3,4-tetrahydro-2-naphthalenol
T3763
SCHEMBL13998125
mfcd00045575
CS-W004310
SY056861
DS-11544
AMY6059
Q27264409
AB88871
DTXSID60870589
Z445987178
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (13)

TimeframeStudies, This Drug (%)All Drugs %
pre-19904 (30.77)18.7374
1990's1 (7.69)18.2507
2000's4 (30.77)29.6817
2010's2 (15.38)24.3611
2020's2 (15.38)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 25.67

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index25.67 (24.57)
Research Supply Index2.64 (2.92)
Research Growth Index4.97 (4.65)
Search Engine Demand Index26.67 (26.88)
Search Engine Supply Index2.00 (0.95)

This Compound (25.67)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other13 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
naphthalene
[no description available]		6.9210naphthalenes;
ortho-fused bicyclic arene		apoptosis inhibitor;
carcinogenic agent;
environmental contaminant;
mouse metabolite;
plant metabolite;
volatile oil component
octopamine
Octopamine: An alpha-adrenergic sympathomimetic amine, biosynthesized from tyramine in the CNS and platelets and also in invertebrate nervous systems. It is used to treat hypotension and as a cardiotonic. The natural D(-) form is more potent than the L(+) form in producing cardiovascular adrenergic responses. It is also a neurotransmitter in some invertebrates.. octopamine : A member of the class of phenylethanolamines that is phenol which is substituted at the para- position by a 2-amino-1-hydroxyethyl group. A biogenic phenylethanolamine which has been found to act as a neurotransmitter, neurohormone or neuromodulator in invertebrates.		2.0210phenylethanolamines;
tyramines		neurotransmitter
sk&f 29661
1,2,3,4-tetrahydroisoquinoline-7-sulfonamide: structure		2.0210
glutamine
Glutamine: A non-essential amino acid present abundantly throughout the body and is involved in many metabolic processes. It is synthesized from GLUTAMIC ACID and AMMONIA. It is the principal carrier of NITROGEN in the body and is an important energy source for many cells.. L-glutamine : An optically active form of glutamine having L-configuration.. glutamine : An alpha-amino acid that consists of butyric acid bearing an amino substituent at position 2 and a carbamoyl substituent at position 4.		2.0210amino acid zwitterion;
glutamine family amino acid;
glutamine;
L-alpha-amino acid;
polar amino acid zwitterion;
proteinogenic amino acid		EC 1.14.13.39 (nitric oxide synthase) inhibitor;
Escherichia coli metabolite;
human metabolite;
metabolite;
micronutrient;
mouse metabolite;
nutraceutical;
Saccharomyces cerevisiae metabolite
tetralin
tetralin: structure given in first source. tetralin : An ortho-fused bicyclic hydrocarbon that is 1,2,3,4-tetrahydro derivative of naphthalene.		2.4120ortho-fused bicyclic hydrocarbon;
tetralins
2-naphthol
2-naphthol: RN given refers to parent cpd. 2-naphthol : A naphthol carrying a hydroxy group at position 2.. naphthols : Any hydroxynaphthalene derivative that has a single hydroxy substituent.		1.9910naphtholantinematodal drug;
genotoxin;
human urinary metabolite;
human xenobiotic metabolite;
mouse metabolite;
radical scavenger
actinorhodin
actinorhodin: structure. actinorhodin : A member of the class of benzoisochromanequinone that is produced by Streptomyces coelicolor A3(2) and exhibits antibiotic activity.		2.0810
lignans
Lignans: A class of dibenzylbutane derivatives which occurs in higher plants and in fluids (bile, serum, urine, etc.) in man and other animals. These compounds, which have a potential anti-cancer role, can be synthesized in vitro by human fecal flora. (From Singleton & Sainsbury, Dictionary of Microbiology and Molecular Biology, 2d ed)		7.0310
betadex
beta-Cyclodextrins: Cyclic GLUCANS consisting of seven (7) glucopyranose units linked by 1,4-glycosidic bonds.		2.0210cyclodextrin
nadp
[no description available]		2.0810
mdl 100907
Serotonin 5-HT2 Receptor Antagonists: Drugs that bind to but do not activate SEROTONIN 5-HT2 RECEPTORS, thereby blocking the actions of SEROTONIN or SEROTONIN 5-HT2 RECEPTOR AGONISTS. Included under this heading are antagonists for one or more specific 5-HT2 receptor subtypes.		2.110
nnc 55-0396
NNC 55-0396: a calcium channel blocker with high selectivity for CaV3 channels over high voltage activated channels; structure in first source. NNC 55-0396 dihydrochloride : The dihydrochloride salt of NNC 55-0396. It is a stable analogue of mibefradil and a highly selective T-type calcium channel blocker.		2.4110hydrochlorideangiogenesis inhibitor;
antineoplastic agent;
apoptosis inducer;
neuroprotective agent;
potassium channel blocker;
T-type calcium channel blocker
ConditionIndicatedRelationship StrengthStudiesTrials
Astrocytoma, Grade IV
[description not available]		02.4110
Glioblastoma
A malignant form of astrocytoma histologically characterized by pleomorphism of cells, nuclear atypia, microhemorrhage, and necrosis. They may arise in any region of the central nervous system, with a predilection for the cerebral hemispheres, basal ganglia, and commissural pathways. Clinical presentation most frequently occurs in the fifth or sixth decade of life with focal neurologic signs or seizures.		07.4110
Cataract, Membranous
[description not available]		02.3320
Cataract
Partial or complete opacity on or in the lens or capsule of one or both eyes, impairing vision or causing blindness. The many kinds of cataract are classified by their morphology (size, shape, location) or etiology (cause and time of occurrence). (Dorland, 27th ed)		02.3320
Body Weight
The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms.		02.0310
Encephalopathy, Toxic
[description not available]		02.0310
Pink Eye
[description not available]		01.9210
Conjunctivitis
INFLAMMATION of the CONJUNCTIVA.		01.9210