Page last updated: 2024-10-25

dapi and Glioblastoma

dapi has been researched along with Glioblastoma in 6 studies

DAPI: RN given refers to parent cpd.

Glioblastoma: A malignant form of astrocytoma histologically characterized by pleomorphism of cells, nuclear atypia, microhemorrhage, and necrosis. They may arise in any region of the central nervous system, with a predilection for the cerebral hemispheres, basal ganglia, and commissural pathways. Clinical presentation most frequently occurs in the fifth or sixth decade of life with focal neurologic signs or seizures.

Research Excerpts

ExcerptRelevanceReference
"The sanguinarine treatment induced the proteolytic activation of caspases and ICAD/DFF45, which was associated with the modulation of the Bcl-2 family, concomitant degradation of poly(ADP ribose) polymerase and phospholipase C-gamma1 protein, and DNA fragmentation."5.34Induction of apoptosis by sanguinarine in C6 rat glioblastoma cells is associated with the modulation of the Bcl-2 family and activation of caspases through downregulation of extracellular signal-regulated kinase and Akt. ( Choi, BT; Choi, YH; Han, MH; Kim, GY; Kim, SO; Kwon, TK; Lee, WH, 2007)
"The sanguinarine treatment induced the proteolytic activation of caspases and ICAD/DFF45, which was associated with the modulation of the Bcl-2 family, concomitant degradation of poly(ADP ribose) polymerase and phospholipase C-gamma1 protein, and DNA fragmentation."1.34Induction of apoptosis by sanguinarine in C6 rat glioblastoma cells is associated with the modulation of the Bcl-2 family and activation of caspases through downregulation of extracellular signal-regulated kinase and Akt. ( Choi, BT; Choi, YH; Han, MH; Kim, GY; Kim, SO; Kwon, TK; Lee, WH, 2007)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (50.00)29.6817
2010's3 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ning, D1
Duong, B1
Thomas, G1
Qiao, Y1
Ma, L1
Wen, Q1
Su, M1
Lu, HF1
Wang, HL1
Chuang, YY1
Tang, YJ1
Yang, JS1
Ma, YS1
Chiang, JH1
Lu, CC1
Yang, JL1
Lai, TY1
Wu, CC1
Chung, JG1
Wang, ZX1
Chen, YY1
Li, BA1
Tan, GW1
Liu, XY1
Shen, SH1
Zhu, HW1
Wang, HD1
Kalev, I1
Kaasik, A1
Zarkovski, A1
Mikelsaar, AV1
Louie, MC1
Revenko, AS1
Zou, JX1
Yao, J1
Chen, HW1
Han, MH1
Kim, SO1
Kim, GY1
Kwon, TK1
Choi, BT1
Lee, WH1
Choi, YH1

Other Studies

6 other studies available for dapi and Glioblastoma

ArticleYear
Mechanical and Morphological Analysis of Cancer Cells on Nanostructured Substrates.
    Langmuir : the ACS journal of surfaces and colloids, 2016, Mar-22, Volume: 32, Issue:11

    Topics: Acrylic Resins; Actins; Animals; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Survival;

2016
Danthron induced apoptosis through mitochondria- and caspase-3-dependent pathways in human brain glioblastoma multiforms GBM 8401 cells.
    Neurochemical research, 2010, Volume: 35, Issue:3

    Topics: Anthraquinones; Apoptosis; Blotting, Western; Brain Neoplasms; Calcium; Caspase 3; Caspase 8; Caspas

2010
Decreased pygopus 2 expression suppresses glioblastoma U251 cell growth.
    Journal of neuro-oncology, 2010, Volume: 100, Issue:1

    Topics: Adult; Analysis of Variance; beta Catenin; Brain Neoplasms; Bromodeoxyuridine; Cell Cycle; Cell Line

2010
Chemokine receptor CCR5 expression in in vitro differentiating human fetal neural stem/progenitor and glioblastoma cells.
    Neuroscience letters, 2006, Feb-06, Volume: 394, Issue:1

    Topics: Brain; Cell Differentiation; Cells, Cultured; Fetus; Gene Expression; Glial Fibrillary Acidic Protei

2006
Direct control of cell cycle gene expression by proto-oncogene product ACTR, and its autoregulation underlies its transforming activity.
    Molecular and cellular biology, 2006, Volume: 26, Issue:10

    Topics: Acetyltransferases; Adenoviridae; Blotting, Western; Breast Neoplasms; Cell Cycle; Cell Cycle Protei

2006
Induction of apoptosis by sanguinarine in C6 rat glioblastoma cells is associated with the modulation of the Bcl-2 family and activation of caspases through downregulation of extracellular signal-regulated kinase and Akt.
    Anti-cancer drugs, 2007, Volume: 18, Issue:8

    Topics: Alkaloids; Animals; Annexin A5; Apoptosis; Benzophenanthridines; Blotting, Western; Caspases; Cell L

2007