perhexiline has been researched along with Glioblastoma in 1 studies
Perhexiline: 2-(2,2-Dicyclohexylethyl)piperidine. Coronary vasodilator used especially for angina of effort. It may cause neuropathy and hepatitis.
Glioblastoma: A malignant form of astrocytoma histologically characterized by pleomorphism of cells, nuclear atypia, microhemorrhage, and necrosis. They may arise in any region of the central nervous system, with a predilection for the cerebral hemispheres, basal ganglia, and commissural pathways. Clinical presentation most frequently occurs in the fifth or sixth decade of life with focal neurologic signs or seizures.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Perhexiline is a compound with a long clinical track record in angina treatment and commonly described as an FAO inhibitor." | 5.56 | Perhexiline Demonstrates FYN-mediated Antitumor Activity in Glioblastoma. ( Buelow, KL; Chinnaiyan, P; Graham, SF; Guastella, AR; Kant, S; Kesarwani, P; Kumar, P; Nakano, I, 2020) |
| "Perhexiline is a compound with a long clinical track record in angina treatment and commonly described as an FAO inhibitor." | 1.56 | Perhexiline Demonstrates FYN-mediated Antitumor Activity in Glioblastoma. ( Buelow, KL; Chinnaiyan, P; Graham, SF; Guastella, AR; Kant, S; Kesarwani, P; Kumar, P; Nakano, I, 2020) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (100.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kant, S | 1 |
| Kesarwani, P | 1 |
| Guastella, AR | 1 |
| Kumar, P | 1 |
| Graham, SF | 1 |
| Buelow, KL | 1 |
| Nakano, I | 1 |
| Chinnaiyan, P | 1 |
1 other study available for perhexiline and Glioblastoma
| Article | Year |
|---|---|
Perhexiline Demonstrates FYN-mediated Antitumor Activity in Glioblastoma.
Topics: Animals; Apoptosis; Brain Neoplasms; Calcium Channel Blockers; Cell Proliferation; Gene Expression R | 2020 |