Compounds > broparoestrol
Page last updated: 2024-11-10

broparoestrol

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Description

broparoestrol: non-steroid compound with estrogenic activity; RN given refers to cpd without isomeric designation; synonym LN 2299 refers to (cis)-isomer; LN 1643 refers to (trans)-isomer; structure in Merck Index, 9th ed, #1451 [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID3032769
SCHEMBL ID146181
MeSH IDM0045591

Synonyms (39)

Synonym
ln 1643
ethylene, 1-bromo-1,2-diphenyl-2-(p-ethylphenyl)-, (e)-
benzene, 1-(2-bromo-1,2-diphenylethenyl)-4-ethyl-, (e)-
bromo-1 (p-ethylphenyl)-2 diphenyl-1,2 ethylene (e) [french]
trans-broparestrol
(e)-1-bromo-1,2-diphenyl-2-(p-ethylphenyl)ethylene
(e)-1-(2-bromo-1,2-diphenylethenyl)-4-ethylbenzene
broparoestrol
1-[(e)-2-bromo-1,2-diphenylethenyl]-4-ethylbenzene
unii-7u06d381uq
longestrol
broparestrol [inn:dcf]
l.n. 107
broparestrol
7u06d381uq ,
1-bromo-2-p-(ethylphenyl)-1,2-diphenylethylene
479-68-5
ln 107
(e,z)-1-brom-2-(4-ethylphenyl)-1,2-diphenylethylen
einecs 207-537-1
broparestrolum
broparoestrolum
2-brom-1-(4-ethylphenyl)-1,2-diphenylethylen
broparestrolum [inn-latin]
broparestrol (e)-
unii-4f4uxv47yi
22393-62-0
4f4uxv47yi ,
bromo-1 (p-ethylphenyl)-2 diphenyl-1,2 ethylene (e)
SCHEMBL146181
ln-1643
(e)-broparestrol
1-(2-bromo-1,2-diphenylethenyl)-4-ethylbenzene, (e)-
ethylene, 1-bromo-2-(p-ethylphenyl)-1,2-diphenyl-, (e)-
broparestrol (e)-form [mi]
Q25091458
DTXSID201203500
(e)-(1-bromo-2-(4-ethylphenyl)ethene-1,2-diyl)dibenzene
AKOS040759886
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (6)

TimeframeStudies, This Drug (%)All Drugs %
pre-19905 (83.33)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (16.67)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other6 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
chloroquine
Chloroquine: The prototypical antimalarial agent with a mechanism that is not well understood. It has also been used to treat rheumatoid arthritis, systemic lupus erythematosus, and in the systemic therapy of amebic liver abscesses.. chloroquine : An aminoquinoline that is quinoline which is substituted at position 4 by a [5-(diethylamino)pentan-2-yl]amino group at at position 7 by chlorine. It is used for the treatment of malaria, hepatic amoebiasis, lupus erythematosus, light-sensitive skin eruptions, and rheumatoid arthritis.		2.0810aminoquinoline;
organochlorine compound;
secondary amino compound;
tertiary amino compound		anticoronaviral agent;
antimalarial;
antirheumatic drug;
autophagy inhibitor;
dermatologic drug
arginine
Arginine: An essential amino acid that is physiologically active in the L-form.. arginine : An alpha-amino acid that is glycine in which the alpha-is substituted by a 3-guanidinopropyl group.		2.0810arginine;
glutamine family amino acid;
L-alpha-amino acid;
proteinogenic amino acid		biomarker;
Escherichia coli metabolite;
micronutrient;
mouse metabolite;
nutraceutical
azacitidine
Azacitidine: A pyrimidine analogue that inhibits DNA methyltransferase, impairing DNA methylation. It is also an antimetabolite of cytidine, incorporated primarily into RNA. Azacytidine has been used as an antineoplastic agent.. 5-azacytidine : An N-glycosyl-1,3,5-triazine that is 4-amino-1,3,5-triazin-2(1H)-one substituted by a beta-D-ribofuranosyl residue via an N-glycosidic linkage. An antineoplastic agent, it is used in the treatment of myeloid leukaemia.		2.0810N-glycosyl-1,3,5-triazine;
nucleoside analogue		antineoplastic agent
decitabine
[no description available]		2.08102'-deoxyribonucleoside
stilbenes
Stilbenes: Organic compounds that contain 1,2-diphenylethylene as a functional group.. trans-stilbene : The trans-isomer of stilbene.		3.2260stilbene
tamoxifen
[no description available]		6.9610stilbenoid;
tertiary amino compound		angiogenesis inhibitor;
antineoplastic agent;
bone density conservation agent;
EC 1.2.3.1 (aldehyde oxidase) inhibitor;
EC 2.7.11.13 (protein kinase C) inhibitor;
estrogen antagonist;
estrogen receptor antagonist;
estrogen receptor modulator
ConditionIndicatedRelationship StrengthStudiesTrials
Astrocytoma, Grade IV
[description not available]		02.0810
Central Nervous System Neoplasm
[description not available]		02.0810
Glioblastoma
A malignant form of astrocytoma histologically characterized by pleomorphism of cells, nuclear atypia, microhemorrhage, and necrosis. They may arise in any region of the central nervous system, with a predilection for the cerebral hemispheres, basal ganglia, and commissural pathways. Clinical presentation most frequently occurs in the fifth or sixth decade of life with focal neurologic signs or seizures.		02.0810
Central Nervous System Neoplasms
Benign and malignant neoplastic processes that arise from or secondarily involve the brain, spinal cord, or meninges.		02.0810
Experimental Mammary Neoplasms
[description not available]		02.3620
Breast Cancer
[description not available]		01.9610
Experimental Neoplasms
[description not available]		01.9610
Breast Neoplasms
Tumors or cancer of the human BREAST.		01.9610