chlorambucil has been researched along with Glioblastoma in 3 studies
Chlorambucil: A nitrogen mustard alkylating agent used as antineoplastic for chronic lymphocytic leukemia, Hodgkin's disease, and others. Although it is less toxic than most other nitrogen mustards, it has been listed as a known carcinogen in the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (Merck Index, 11th ed)
chlorambucil : A monocarboxylic acid that is butanoic acid substituted at position 4 by a 4-[bis(2-chloroethyl)amino]phenyl group. A chemotherapy drug that can be used in combination with the antibody obinutuzumab for the treatment of chronic lymphocytic leukemia.
Glioblastoma: A malignant form of astrocytoma histologically characterized by pleomorphism of cells, nuclear atypia, microhemorrhage, and necrosis. They may arise in any region of the central nervous system, with a predilection for the cerebral hemispheres, basal ganglia, and commissural pathways. Clinical presentation most frequently occurs in the fifth or sixth decade of life with focal neurologic signs or seizures.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Twenty-one consecutive patients with histologically confirmed glioblastoma multiforme were treated with prednimustine (130 mg/m2 for 5 days every 3 weeks) adjuvant to surgery and radiation therapy." | 7.67 | Phase II trial of prednimustine in glioblastoma multiforme. ( Andersen, J; Christensen, L; Kongsholm, H, 1984) |
| "Twenty-one consecutive patients with histologically confirmed glioblastoma multiforme were treated with prednimustine (130 mg/m2 for 5 days every 3 weeks) adjuvant to surgery and radiation therapy." | 3.67 | Phase II trial of prednimustine in glioblastoma multiforme. ( Andersen, J; Christensen, L; Kongsholm, H, 1984) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Andersen, J | 1 |
| Christensen, L | 1 |
| Kongsholm, H | 1 |
| Mark, JB | 1 |
| Flanigan, S | 1 |
| Le Goff, P | 1 |
| Le Menn, G | 1 |
3 other studies available for chlorambucil and Glioblastoma
| Article | Year |
|---|---|
Phase II trial of prednimustine in glioblastoma multiforme.
Topics: Adolescent; Adult; Aged; Brain Neoplasms; Chlorambucil; Combined Modality Therapy; Drug Evaluation; | 1984 |
Chemotherapy of malignant brain tumors.
Topics: Brain Neoplasms; Carotid Arteries; Chemotherapy, Cancer, Regional Perfusion; Chlorambucil; Glioblast | 1966 |
[Cancer and immunosuppressive treatment. Apropos of 2 cases].
Topics: Arthritis, Rheumatoid; Autoimmune Diseases; Brain Neoplasms; Carcinoma, Squamous Cell; Chlorambucil; | 1974 |