| Condition | Indicated | Relationship Strength | Studies | Trials |
|---|
Benign Neoplasms, Brain
[description not available] | 0 | 7.26 | 11 | 4 |
Glial Cell Tumors
[description not available] | 0 | 5.16 | 11 | 1 |
Brain Neoplasms
Neoplasms of the intracranial components of the central nervous system, including the cerebral hemispheres, basal ganglia, hypothalamus, thalamus, brain stem, and cerebellum. Brain neoplasms are subdivided into primary (originating from brain tissue) and secondary (i.e., metastatic) forms. Primary neoplasms are subdivided into benign and malignant forms. In general, brain tumors may also be classified by age of onset, histologic type, or presenting location in the brain. | 0 | 7.26 | 11 | 4 |
Glioma
Benign and malignant central nervous system neoplasms derived from glial cells (i.e., astrocytes, oligodendrocytes, and ependymocytes). Astrocytes may give rise to astrocytomas (ASTROCYTOMA) or glioblastoma multiforme (see GLIOBLASTOMA). Oligodendrocytes give rise to oligodendrogliomas (OLIGODENDROGLIOMA) and ependymocytes may undergo transformation to become EPENDYMOMA; CHOROID PLEXUS NEOPLASMS; or colloid cysts of the third ventricle. (From Escourolle et al., Manual of Basic Neuropathology, 2nd ed, p21) | 0 | 5.16 | 11 | 1 |
Astrocytoma, Grade IV
[description not available] | 0 | 5.21 | 4 | 3 |
Arachnoidal Cerebellar Sarcoma, Circumscribed
[description not available] | 0 | 1.98 | 1 | 0 |
Glioblastoma
A malignant form of astrocytoma histologically characterized by pleomorphism of cells, nuclear atypia, microhemorrhage, and necrosis. They may arise in any region of the central nervous system, with a predilection for the cerebral hemispheres, basal ganglia, and commissural pathways. Clinical presentation most frequently occurs in the fifth or sixth decade of life with focal neurologic signs or seizures. | 0 | 5.21 | 4 | 3 |
Medulloblastoma
A malignant neoplasm that may be classified either as a glioma or as a primitive neuroectodermal tumor of childhood (see NEUROECTODERMAL TUMOR, PRIMITIVE). The tumor occurs most frequently in the first decade of life with the most typical location being the cerebellar vermis. Histologic features include a high degree of cellularity, frequent mitotic figures, and a tendency for the cells to organize into sheets or form rosettes. Medulloblastoma have a high propensity to spread throughout the craniospinal intradural axis. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2060-1) | 0 | 1.98 | 1 | 0 |
HIV Coinfection
[description not available] | 0 | 3.37 | 1 | 1 |
Neutropenia
A decrease in the number of NEUTROPHILS found in the blood. | 0 | 5.47 | 4 | 4 |
HIV Infections
Includes the spectrum of human immunodeficiency virus infections that range from asymptomatic seropositivity, thru AIDS-related complex (ARC), to acquired immunodeficiency syndrome (AIDS). | 0 | 3.37 | 1 | 1 |
Diffuse Mixed Small and Large Cell Lymphoma
[description not available] | 0 | 4.7 | 2 | 1 |
T-Cell Lymphoma
[description not available] | 0 | 2.9 | 1 | 0 |
Lymphoma, Non-Hodgkin
Any of a group of malignant tumors of lymphoid tissue that differ from HODGKIN DISEASE, being more heterogeneous with respect to malignant cell lineage, clinical course, prognosis, and therapy. The only common feature among these tumors is the absence of giant REED-STERNBERG CELLS, a characteristic of Hodgkin's disease. | 0 | 4.7 | 2 | 1 |
Lymphoma, T-Cell
A group of heterogeneous lymphoid tumors representing malignant transformations of T-lymphocytes. | 0 | 2.9 | 1 | 0 |
Breast Cancer
[description not available] | 0 | 5.18 | 6 | 2 |
Breast Neoplasms
Tumors or cancer of the human BREAST. | 0 | 5.18 | 6 | 2 |
Experimental Leukemia
[description not available] | 0 | 4.68 | 2 | 1 |
Cancer of Stomach
[description not available] | 0 | 4.68 | 2 | 1 |
Acute Myelogenous Leukemia
[description not available] | 0 | 6.39 | 4 | 4 |
Stomach Neoplasms
Tumors or cancer of the STOMACH. | 0 | 4.68 | 2 | 1 |
Leukemia, Myeloid, Acute
Clonal expansion of myeloid blasts in bone marrow, blood, and other tissue. Myeloid leukemias develop from changes in cells that normally produce NEUTROPHILS; BASOPHILS; EOSINOPHILS; and MONOCYTES. | 0 | 6.39 | 4 | 4 |
Benign Neoplasms
[description not available] | 0 | 5.21 | 4 | 3 |
Neoplasms
New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms. | 0 | 5.21 | 4 | 3 |
Carcinoma, Anaplastic
[description not available] | 0 | 1.99 | 1 | 0 |
Cancer of Ovary
[description not available] | 0 | 1.99 | 1 | 0 |
Carcinoma
A malignant neoplasm made up of epithelial cells tending to infiltrate the surrounding tissues and give rise to metastases. It is a histological type of neoplasm and not a synonym for cancer. | 0 | 1.99 | 1 | 0 |
Ovarian Neoplasms
Tumors or cancer of the OVARY. These neoplasms can be benign or malignant. They are classified according to the tissue of origin, such as the surface EPITHELIUM, the stromal endocrine cells, and the totipotent GERM CELLS. | 0 | 1.99 | 1 | 0 |
Adenocarcinoma, Basal Cell
[description not available] | 0 | 1.99 | 1 | 0 |
Cancer of Colon
[description not available] | 0 | 1.99 | 1 | 0 |
Leukemia P388
An experimental lymphocytic leukemia originally induced in DBA/2 mice by painting with methylcholanthrene. | 0 | 2.67 | 3 | 0 |
Adenocarcinoma
A malignant epithelial tumor with a glandular organization. | 0 | 1.99 | 1 | 0 |
Colonic Neoplasms
Tumors or cancer of the COLON. | 0 | 1.99 | 1 | 0 |
Metastase
[description not available] | 0 | 4.34 | 2 | 2 |
Neoplasm Metastasis
The transfer of a neoplasm from one organ or part of the body to another remote from the primary site. | 0 | 4.34 | 2 | 2 |
Leukemia, Megakaryocytic
[description not available] | 0 | 1.99 | 1 | 0 |
Leukemia, Megakaryoblastic, Acute
An acute myeloid leukemia in which 20-30% of the bone marrow or peripheral blood cells are of megakaryocyte lineage. MYELOFIBROSIS or increased bone marrow RETICULIN is common. | 0 | 1.99 | 1 | 0 |
Granuloma, Hodgkin
[description not available] | 0 | 3.77 | 2 | 1 |
Leukocytopenia
[description not available] | 0 | 4.84 | 4 | 2 |
Thrombopenia
[description not available] | 0 | 3.77 | 2 | 1 |
Emesis
[description not available] | 0 | 5.21 | 4 | 3 |
Anorexia
The lack or loss of APPETITE accompanied by an aversion to food and the inability to eat. It is the defining characteristic of the disorder ANOREXIA NERVOSA. | 0 | 4.99 | 3 | 3 |
Hodgkin Disease
A malignant disease characterized by progressive enlargement of the lymph nodes, spleen, and general lymphoid tissue. In the classical variant, giant usually multinucleate Hodgkin's and REED-STERNBERG CELLS are present; in the nodular lymphocyte predominant variant, lymphocytic and histiocytic cells are seen. | 0 | 3.77 | 2 | 1 |
Leukopenia
A decrease in the number of LEUKOCYTES in a blood sample below the normal range (LEUKOCYTE COUNT less than 4000). | 0 | 4.84 | 4 | 2 |
Nausea
An unpleasant sensation in the stomach usually accompanied by the urge to vomit. Common causes are early pregnancy, sea and motion sickness, emotional stress, intense pain, food poisoning, and various enteroviruses. | 0 | 5.65 | 5 | 4 |
Thrombocytopenia
A subnormal level of BLOOD PLATELETS. | 0 | 3.77 | 2 | 1 |
Vomiting
The forcible expulsion of the contents of the STOMACH through the MOUTH. | 0 | 5.21 | 4 | 3 |
Acute Lymphoid Leukemia
[description not available] | 0 | 4.99 | 3 | 3 |
Precursor Cell Lymphoblastic Leukemia-Lymphoma
A neoplasm characterized by abnormalities of the lymphoid cell precursors leading to excessive lymphoblasts in the marrow and other organs. It is the most common cancer in children and accounts for the vast majority of all childhood leukemias. | 0 | 4.99 | 3 | 3 |
Anticipatory Vomiting
[description not available] | 0 | 3.38 | 1 | 1 |
Leukemia, Lymphocytic, T Cell
[description not available] | 0 | 2 | 1 | 0 |
Leukemia, T-Cell
A malignant disease of the T-LYMPHOCYTES in the bone marrow, thymus, and/or blood. | 0 | 2 | 1 | 0 |
Granulocytic Leukemia
[description not available] | 0 | 3.38 | 1 | 1 |
Acute Disease
Disease having a short and relatively severe course. | 0 | 3.38 | 1 | 1 |
Leukemia, Myeloid
Form of leukemia characterized by an uncontrolled proliferation of the myeloid lineage and their precursors (MYELOID PROGENITOR CELLS) in the bone marrow and other sites. | 0 | 3.38 | 1 | 1 |
Local Neoplasm Recurrence
[description not available] | 0 | 4.35 | 2 | 2 |
Central Nervous System Disease
[description not available] | 0 | 3.38 | 1 | 1 |
Cholera Infantum
[description not available] | 0 | 3.38 | 1 | 1 |
Central Nervous System Diseases
Diseases of any component of the brain (including the cerebral hemispheres, diencephalon, brain stem, and cerebellum) or the spinal cord. | 0 | 3.38 | 1 | 1 |
Anaplastic Astrocytoma
[description not available] | 0 | 4.35 | 2 | 2 |
Astrocytoma
Neoplasms of the brain and spinal cord derived from glial cells which vary from histologically benign forms to highly anaplastic and malignant tumors. Fibrillary astrocytomas are the most common type and may be classified in order of increasing malignancy (grades I through IV). In the first two decades of life, astrocytomas tend to originate in the cerebellar hemispheres; in adults, they most frequently arise in the cerebrum and frequently undergo malignant transformation. (From Devita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2013-7; Holland et al., Cancer Medicine, 3d ed, p1082) | 0 | 4.35 | 2 | 2 |
Cardiomyopathies, Primary
[description not available] | 0 | 3.39 | 1 | 1 |
Anaplastic Oligodendroglioma
[description not available] | 0 | 3.39 | 1 | 1 |
Cardiomyopathies
A group of diseases in which the dominant feature is the involvement of the CARDIAC MUSCLE itself. Cardiomyopathies are classified according to their predominant pathophysiological features (DILATED CARDIOMYOPATHY; HYPERTROPHIC CARDIOMYOPATHY; RESTRICTIVE CARDIOMYOPATHY) or their etiological/pathological factors (CARDIOMYOPATHY, ALCOHOLIC; ENDOCARDIAL FIBROELASTOSIS). | 0 | 3.39 | 1 | 1 |
Oligodendroglioma
A relatively slow-growing glioma that is derived from oligodendrocytes and tends to occur in the cerebral hemispheres, thalamus, or lateral ventricle. They may present at any age, but are most frequent in the third to fifth decades, with an earlier incidence peak in the first decade. Histologically, these tumors are encapsulated, relatively avascular, and tend to form cysts and microcalcifications. Neoplastic cells tend to have small round nuclei surrounded by unstained nuclei. The tumors may vary from well-differentiated to highly anaplastic forms. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, p2052; Adams et al., Principles of Neurology, 6th ed, p655) | 0 | 3.39 | 1 | 1 |
Nervous System Disorders
[description not available] | 0 | 2 | 1 | 0 |
Nervous System Diseases
Diseases of the central and peripheral nervous system. This includes disorders of the brain, spinal cord, cranial nerves, peripheral nerves, nerve roots, autonomic nervous system, neuromuscular junction, and muscle. | 0 | 2 | 1 | 0 |
Body Weight
The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms. | 0 | 2 | 1 | 0 |
Brain Swelling
[description not available] | 0 | 2 | 1 | 0 |
Disease Models, Animal
Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases. | 0 | 2 | 1 | 0 |
Brain Edema
Increased intracellular or extracellular fluid in brain tissue. Cytotoxic brain edema (swelling due to increased intracellular fluid) is indicative of a disturbance in cell metabolism, and is commonly associated with hypoxic or ischemic injuries (see HYPOXIA, BRAIN). An increase in extracellular fluid may be caused by increased brain capillary permeability (vasogenic edema), an osmotic gradient, local blockages in interstitial fluid pathways, or by obstruction of CSF flow (e.g., obstructive HYDROCEPHALUS). (From Childs Nerv Syst 1992 Sep; 8(6):301-6) | 0 | 2 | 1 | 0 |
Cancer of Lung
[description not available] | 0 | 2.38 | 2 | 0 |
Lung Neoplasms
Tumors or cancer of the LUNG. | 0 | 2.38 | 2 | 0 |
Granulocytic Leukemia, Chronic
[description not available] | 0 | 2.38 | 2 | 0 |
Leukemia, Myelogenous, Chronic, BCR-ABL Positive
Clonal hematopoetic disorder caused by an acquired genetic defect in PLURIPOTENT STEM CELLS. It starts in MYELOID CELLS of the bone marrow, invades the blood and then other organs. The condition progresses from a stable, more indolent, chronic phase (LEUKEMIA, MYELOID, CHRONIC PHASE) lasting up to 7 years, to an advanced phase composed of an accelerated phase (LEUKEMIA, MYELOID, ACCELERATED PHASE) and BLAST CRISIS. | 0 | 2.38 | 2 | 0 |
Cardiac Diseases
[description not available] | 0 | 1.97 | 1 | 0 |
Heart Diseases
Pathological conditions involving the HEART including its structural and functional abnormalities. | 0 | 1.97 | 1 | 0 |
Carcinoma, Non-Small Cell Lung
[description not available] | 0 | 1.97 | 1 | 0 |
Carcinoma, Non-Small-Cell Lung
A heterogeneous aggregate of at least three distinct histological types of lung cancer, including SQUAMOUS CELL CARCINOMA; ADENOCARCINOMA; and LARGE CELL CARCINOMA. They are dealt with collectively because of their shared treatment strategy. | 0 | 1.97 | 1 | 0 |
Leukemia L 1210
[description not available] | 0 | 1.97 | 1 | 0 |
Experimental Neoplasms
[description not available] | 0 | 1.97 | 1 | 0 |
Benign Meningeal Neoplasms
[description not available] | 0 | 1.97 | 1 | 0 |
Meningeal Neoplasms
Benign and malignant neoplastic processes that arise from or secondarily involve the meningeal coverings of the brain and spinal cord. | 0 | 1.97 | 1 | 0 |