bioallethrin: RN given refers to (1R-(1alpha(S*),3beta))-isomer; see also record for ALLETHRIN which is cpd without isomeric designation [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
bioallethrin : A partly enantiopure variant of allethrin consisting of a mixture of two allethrin isomers (1R,trans;1R and 1R,trans;1S) in an approximate ratio of 1:1. Widely registered mosquito adulticide and spatial repellent. Bioallethrin is a synthetic pyrethroid used as a pesticide against household pest insects such as mosquitoes, houseflies and cockroaches. [Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]
| ID Source | ID |
|---|---|
| PubMed CID | 15558638 |
| CHEMBL ID | 1788403 |
| CHEBI ID | 39118 |
| CHEBI ID | 143255 |
| SCHEMBL ID | 411848 |
| MeSH ID | M0070027 |
| Synonym |
|---|
| bioaltrina |
| cyclopropanecarboxylic acid, 2,2-dimethyl-3-(2-methyl-1-propen-1-yl)-, 2-methyl-4-oxo-3-(2-propen-1-yl)-2-cyclopenten-1-yl ester |
| allethrin i |
| unii-0x03ii877m |
| ru 27436 |
| (rs)-3-allyl-2-methyl-4-oxocyclopent-2-enyl (+-)-cis,trans-chrysanthemate |
| bioallethrin [ban] |
| bioallethrin [bsi] |
| caswell no. 025 |
| 2-methyl-4-oxo-3-(2-propenyl)-2-cyclopenten-1-yl 2,2-dimethyl-3-(2-methyl-1-propenyl)cyclopropanecar |
| dl-2-allyl-4-hydroxy-3-methyl-2-cyclopenten-1-one ester of d-trans-2,2-dimethyl-3-(2-methylpropenyl) |
| bioaltrina [portuguese] |
| (rs)-3-allyl-2-methyl-4-oxocyclopent-2-enyl (1r,3r)-2,2-dimethyl-3-(2-methylprop-1-enyl)cyclopropanecarboxylate |
| (+-)-allerethonyl (+-)-cis,trans-chrysanthemate |
| einecs 209-542-4 |
| (+)-trans-chrysanthemumic acid ester of (+-)-allethrolone |
| 3-allyl-4-methyl-2-oxo-3-cyclopenten-1-yl ester of 2,2-dimethyl-3-(2-methylpropenyl)cyclopropanecarboxylic acid |
| epa pesticide chemical code 004001 |
| exthrin |
| wasp stopper cf |
| allethrin coil |
| esbiol tm intermediate 3336 |
| ccris 2494 |
| allethrin [bsi:iso] |
| allylrethronyl dl-cis-trans-chrysanthemate |
| ai3-17510 |
| nsc 11782 |
| 2-allyl-4-hydroxy-3-methyl-2-cyclopenten-1-one ester of chrysanthemummono-carboxylic acid |
| ent 17,510 |
| dl-2-allyl-4-hydroxy-3-methyl-2-cyclopenten-1-one ester of dl cis/trans 2,2-dimethyl-3-(2-methylpropenyl)-cyclopropanecarboxylic acid |
| cyclopropanecarboxylic acid, 2,2-dimethyl-3-(2-methyl-1-propenyl)-, 2-methyl-4-oxo-3-(2-propenyl)-2-cyclopentene-1-yl ester |
| cyclopropanecarboxylic acid, 2,2-dimethyl-3-(2-methylpropenyl)-, ester with 2-allyl-4-hydroxy-3-methyl-2-cyclopenten-1-one (van) |
| chrysanthemummonocarboxylic acid, 3-allyl-3-methyl-4-oxo-2-cyclopenten-1-yl ester |
| bioaletrina [portuguese] |
| 2,2-dimethyl-3-(2-methyl-1-propenyl)cyclopropanecarboxylic acid, ester with 2-allyl-4-hydroxy-3-methyl-2-cyclopenten-1-one |
| dl-3-allyl-2-methyl-4-oxocyclopent-2-enyl dl-cis trans chrysanthemate |
| d,l-2-allyl-4-hydroxy-3-methyl-2-cyclopenten-1-one-d,l-chrysanthemum monocarboxylate |
| pynamin-forte |
| 3-allyl-4-keto-2-methylcyclopentenyl chrysanthemummonocarboxylate |
| allethrine [iso-french] |
| binamin forte |
| depallethrin |
| 2-cyclopenten-1-one, 2-allyl-4-hydroxy-3-methyl-, 2,2-dimethyl-3-(2-methylpropenyl)cyclopropanecarboxylate |
| oms 3045 |
| bioallethrin |
| nsc-11782 |
| trans-allethrin |
| 2-methyl-4-oxo-3-(2-propenyl)-2-cyclopenten-1-yl trans-(+)-2,2-dimethyl-3-(2-methyl-1-propenyl)cyclopropanecarboxylate |
| 3-allyl-2-methyl-4-oxocyclopent-2-en-1-yl (1r,3r)-2,2-dimethyl-3-(2-methylprop-1-en-1-yl)cyclopropanecarboxylate |
| CHEBI:39118 , |
| 2-methyl-4-oxo-3-(prop-2-en-1-yl)cyclopent-2-en-1-yl (1r,3r)-2,2-dimethyl-3-(2-methylprop-1-en-1-yl)cyclopropanecarboxylate |
| 2,2-dimethyl-3-(2-methyl-1-propenyl)cyclopropanecarboxylic acid 2-methyl-4-oxo-3-(2-propenyl)-2-cyclopenten-1-yl ester |
| (+)-trans-allethrin |
| LMPR0102060007 |
| 2-methyl-4-oxo-3-(2-propen-1-yl)-2-cyclopenten-1-yl (1r,3r)-2,2-dimethyl-3-(2-methyl-1-propen-1-yl)cyclopropanecarboxylate |
| CHEBI:143255 , |
| 260359-57-7 |
| (rs)-3-allyl-2-methyl-4-oxocyclopent-2-enyl (1r)-trans-2,2-dimethyl-3-(2-methylprop-1-enyl)cyclopropanecarboxylate |
| g79dm7o471 , |
| cyclopropanecarboxylic acid, 2,2-dimethyl-3-(2-methyl-1-propenyl)-, 2-methyl-4-oxo-3-(2-propenyl)-2-cyclopenten-1-yl ester, (1r,3r)- |
| unii-g79dm7o471 |
| AKOS015965038 |
| SCHEMBL411848 |
| allethrin [iso] |
| 2-methyl-4-oxo-3-(2-propen-1-yl)-2-cyclopenten-1-yl 2,2-dimethyl-3-(2-methyl-1-propen-1-yl)cyclopropanecarboxylate |
| bioallethrin [mart.] |
| bioallethrin [who-dd] |
| DTXSID00180679 |
| CHEMBL1788403 |
| cyclopropanecarboxylic acid, 2,2-dimethyl-3-(2-methyl-1-propen-1-yl)-, 2-methyl-4-oxo-3-(2-propen-1-yl)-2-cyclopenten-1-yl ester, (1r,3r)-; cyclopropanecarboxylic acid, 2,2-dimethyl-3-(2-methyl-1-propenyl)-, 2-methyl-4-oxo-3-(2-propenyl)-2-cyclopenten-1-y |
| Q27118146 |
| cyclopropanecarboxylicacid, 2,2-dimethyl-3-(2-methyl-1-propen-1-yl)-,2-methyl-4-oxo-3-(2-propen-1-yl)-2-cyclopenten-1-yl ester, (1r,3r)- |
| (2-methyl-4-oxo-3-prop-2-enylcyclopent-2-en-1-yl) (1r,3r)-2,2-dimethyl-3-(2-methylprop-1-enyl)cyclopropane-1-carboxylate |
| cyclopropanecarboxylicacid,2,2-dimethyl-3-(2-methyl-1-propen-1-yl)-,2-methyl-4-oxo-3-(2-propen-1-yl)-2-cyclopenten-1-yl ester,(1r,3r)- |
| depallethrine |
| (rs)-3-allyl-2-methyl-4-oxocyclopent-2-enyl (1r)-trans-chrysanthemate |
| duocide (veterinary) |
| bioallethrin (mart.) |
Bioallethrin is an insecticide that is widely used to control mosquitoes, fleas and cockroaches. It was found to be a weak mutagen in the TA 100 and TA 98 strains of S. cerevisiae.
| Excerpt | Reference | Relevance |
|---|---|---|
| "Bioallethrin is an insecticide that is widely used to control mosquitoes, fleas and cockroaches. " | ( Bioallethrin-induced generation of reactive species and oxidative damage in isolated human erythrocytes. Arif, A; Mahmood, R; Salam, S, 2020) | 3.44 |
| "Bioallethrin is a synthetic pesticide that is widely used to control insect pests. " | ( Bioallethrin enhances generation of ROS, damages DNA, impairs the redox system and causes mitochondrial dysfunction in human lymphocytes. Arif, A; Mahmood, R; Quds, R, 2021) | 3.51 |
| "Bioallethrin was found to be a weak mutagen in the TA 100 and TA 98 strains of S." | ( [The mutagenicity of some insecticides in the Salmonella/microsome test system]. Diril, N; Izbirak, A; Sümer, S, 1990) | 1 |
Bioallethrin treatment altered the specific activities of antioxidant enzymes and diminished the antioxidant power of cells. Treatment resulted in loss of cell viability (> 30% at 200 µM bioallethin)
| Excerpt | Reference | Relevance |
|---|---|---|
| "Bioallethrin-treated erythrocytes showed a significant increase in oxidative stress markers, like protein and lipid oxidation, accompanied by decrease in free amino groups and ratio of reduced to oxidized glutathione." | ( Esculin protects human blood cells from bioallethrin-induced toxicity: An ex vivo study. Arif, A; Mahmood, R; Quds, R; Salam, S, 2023) | 1.9 |
| "Bioallethrin treatment altered the specific activities of antioxidant enzymes and diminished the antioxidant power of cells." | ( Bioallethrin-induced generation of reactive species and oxidative damage in isolated human erythrocytes. Arif, A; Mahmood, R; Salam, S, 2020) | 2.72 |
| "Bioallethrin treatment resulted in loss of cell viability (> 30% at 200 µM bioallethrin)." | ( Bioallethrin enhances generation of ROS, damages DNA, impairs the redox system and causes mitochondrial dysfunction in human lymphocytes. Arif, A; Mahmood, R; Quds, R, 2021) | 2.79 |
| Excerpt | Reference | Relevance |
|---|---|---|
| "Bioallethrin, a household insecticide, is a member of the pyrethroid family and is known for its adverse effects on human health." | ( Esculin protects human blood cells from bioallethrin-induced toxicity: An ex vivo study. Arif, A; Mahmood, R; Quds, R; Salam, S, 2023) | 2.62 |
| Excerpt | Relevance | Reference |
|---|---|---|
| "To evaluate the efficacy and to determine the minimum effective dosage of four pediculicides against head louse infestation, as well as to select a safe, effective, practical, and cheap agent, 1,657 infested school children in 25 primary schools in Szu-Hu, Kou-Hu, and Ku-Keng Districts of Yunlin County were treated and 1,611 of them were examined." | ( Evaluation of efficacy of four pediculicides against head louse (Pediculus capitis) infestation. Chow, CY; Chuang, CH; Chung, WC; Fan, PC; Hsu, HM; Kuo, CL; Lin, CY, 1992) | 0.28 |
| " These results indicate that neonatal exposure to bioallethrin has the potential to increase susceptibility of the adult mouse to a new exposure at a dosage that does not have any effect in animals treated neonatally with vehicle." | ( Changes in behavior and muscarinic receptor density after neonatal and adult exposure to bioallethrin. Eriksson, P; Fredriksson, A; Talts, U, ) | 0.61 |
| "The present investigation was conducted to understand better possible confounding factors caused by direct dosing of neonatal mice during the pre-weaning developmental period." | ( Critical analysis of potential body temperature confounders on neurochemical endpoints caused by direct dosing and maternal separation in neonatal mice: a study of bioallethrin and deltamethrin interactions with temperature on brain muscarinic receptors. Pauluhn, J; Schmuck, G, ) | 0.33 |
| Class | Description |
|---|---|
| allethrin | |
| trans-allethrin | |
| [compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res] | |
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|---|---|
| pre-1990 | 3 (7.50) | 18.7374 |
| 1990's | 13 (32.50) | 18.2507 |
| 2000's | 12 (30.00) | 29.6817 |
| 2010's | 7 (17.50) | 24.3611 |
| 2020's | 5 (12.50) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.
| This Compound (34.36) All Compounds (24.57) |
| Publication Type | This drug (%) | All Drugs (%) |
|---|---|---|
| Trials | 1 (2.27%) | 5.53% |
| Reviews | 0 (0.00%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 1 (2.27%) | 0.25% |
| Other | 42 (95.45%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||