menthol has been researched along with Glioblastoma in 2 studies
Menthol: A monoterpene cyclohexanol produced from mint oils.
Glioblastoma: A malignant form of astrocytoma histologically characterized by pleomorphism of cells, nuclear atypia, microhemorrhage, and necrosis. They may arise in any region of the central nervous system, with a predilection for the cerebral hemispheres, basal ganglia, and commissural pathways. Clinical presentation most frequently occurs in the fifth or sixth decade of life with focal neurologic signs or seizures.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This study examined the effect of menthol, an agonist for transient receptor potential melastatin 8 (TRPM8) ion channels, to increase intracellular Ca2+ concentration, [Ca2+]i, in human glioblastoma cells (DBTRG cells), which resulted in activation of the large-conductance Ca2+-activated K+ membrane ion channels (BK channels)." | 7.75 | Menthol increases human glioblastoma intracellular Ca2+, BK channel activity and cell migration. ( Bartley, JW; Wondergem, R, 2009) |
| "This study examined the effect of menthol, an agonist for transient receptor potential melastatin 8 (TRPM8) ion channels, to increase intracellular Ca2+ concentration, [Ca2+]i, in human glioblastoma cells (DBTRG cells), which resulted in activation of the large-conductance Ca2+-activated K+ membrane ion channels (BK channels)." | 3.75 | Menthol increases human glioblastoma intracellular Ca2+, BK channel activity and cell migration. ( Bartley, JW; Wondergem, R, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wondergem, R | 2 |
| Bartley, JW | 1 |
| Ecay, TW | 1 |
| Mahieu, F | 1 |
| Owsianik, G | 1 |
| Nilius, B | 1 |
2 other studies available for menthol and Glioblastoma
| Article | Year |
|---|---|
Menthol increases human glioblastoma intracellular Ca2+, BK channel activity and cell migration.
Topics: Brain Neoplasms; Calcium; Calcium Signaling; Cell Line, Tumor; Cell Movement; Glioblastoma; Humans; | 2009 |
HGF/SF and menthol increase human glioblastoma cell calcium and migration.
Topics: Boron Compounds; Calcium; Cell Movement; Central Nervous System Neoplasms; Glioblastoma; Hepatocyte | 2008 |