juglone has been researched along with Glioblastoma in 4 studies
juglone: structure
juglone : A hydroxy-1,4-naphthoquinone that is 1,4-naphthoquinone in which the hydrogen at position 5 has been replaced by a hydroxy group. A plant-derived 1,4-naphthoquinone with confirmed antibacterial and antitumor activities.
Glioblastoma: A malignant form of astrocytoma histologically characterized by pleomorphism of cells, nuclear atypia, microhemorrhage, and necrosis. They may arise in any region of the central nervous system, with a predilection for the cerebral hemispheres, basal ganglia, and commissural pathways. Clinical presentation most frequently occurs in the fifth or sixth decade of life with focal neurologic signs or seizures.
| Excerpt | Relevance | Reference |
|---|---|---|
| " In this paper, we present the effects of juglone alone and in combination with temozolomide on glioblastoma cells." | 5.91 | Juglone in Combination with Temozolomide Shows a Promising Epigenetic Therapeutic Effect on the Glioblastoma Cell Line. ( Barciszewska, AM; Belter, A; Gawrońska, I; Giel-Pietraszuk, M; Naskręt-Barciszewska, MZ, 2023) |
| "Juglone could inhibit the growth of TSCs in gliomas through the activation of ROS-p38-MAPK pathway in vitro, and the anti-glioma effect was validated in vivo, which offers a potential therapeutic agent to gliomas." | 5.46 | Juglone induces apoptosis of tumor stem-like cells through ROS-p38 pathway in glioblastoma. ( Chen, L; Hua, W; Mao, Y; Wu, J; Xu, Y; Zhang, H; Zhang, J; Zhang, Y; Zhu, W, 2017) |
| " In this paper, we present the effects of juglone alone and in combination with temozolomide on glioblastoma cells." | 1.91 | Juglone in Combination with Temozolomide Shows a Promising Epigenetic Therapeutic Effect on the Glioblastoma Cell Line. ( Barciszewska, AM; Belter, A; Gawrońska, I; Giel-Pietraszuk, M; Naskręt-Barciszewska, MZ, 2023) |
| "Juglone could inhibit the growth of TSCs in gliomas through the activation of ROS-p38-MAPK pathway in vitro, and the anti-glioma effect was validated in vivo, which offers a potential therapeutic agent to gliomas." | 1.46 | Juglone induces apoptosis of tumor stem-like cells through ROS-p38 pathway in glioblastoma. ( Chen, L; Hua, W; Mao, Y; Wu, J; Xu, Y; Zhang, H; Zhang, J; Zhang, Y; Zhu, W, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (75.00) | 24.3611 |
| 2020's | 1 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Barciszewska, AM | 1 |
| Belter, A | 1 |
| Gawrońska, I | 1 |
| Giel-Pietraszuk, M | 1 |
| Naskręt-Barciszewska, MZ | 1 |
| Wu, J | 1 |
| Zhang, H | 1 |
| Xu, Y | 1 |
| Zhang, J | 1 |
| Zhu, W | 1 |
| Zhang, Y | 1 |
| Chen, L | 1 |
| Hua, W | 1 |
| Mao, Y | 1 |
| Wang, J | 1 |
| Liu, K | 1 |
| Wang, XF | 1 |
| Sun, DJ | 1 |
| Meskelevicius, D | 1 |
| Sidlauskas, K | 1 |
| Bagdonaviciute, R | 1 |
| Liobikas, J | 1 |
| Majiene, D | 1 |
4 other studies available for juglone and Glioblastoma
| Article | Year |
|---|---|
Juglone in Combination with Temozolomide Shows a Promising Epigenetic Therapeutic Effect on the Glioblastoma Cell Line.
Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Drug Resistance, Neoplasm; Epi | 2023 |
Juglone induces apoptosis of tumor stem-like cells through ROS-p38 pathway in glioblastoma.
Topics: Animals; Antineoplastic Agents; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Survival; Gliobla | 2017 |
Juglone reduces growth and migration of U251 glioblastoma cells and disrupts angiogenesis.
Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Cell Growth Processes; Cell Line, Tumor; Cell Movem | 2017 |
Juglone Exerts Cytotoxic, Anti-proliferative and Anti-invasive Effects on Glioblastoma Multiforme in a Cell Culture Model.
Topics: Animals; Antineoplastic Agents; Cell Death; Cell Line, Tumor; Cell Proliferation; Cell Survival; Gli | 2016 |