pinacidil has been researched along with Glioblastoma in 1 studies
Pinacidil: A guanidine that opens POTASSIUM CHANNELS producing direct peripheral vasodilatation of the ARTERIOLES. It reduces BLOOD PRESSURE and peripheral resistance and produces fluid retention. (Martindale The Extra Pharmacopoeia, 31st ed)
Glioblastoma: A malignant form of astrocytoma histologically characterized by pleomorphism of cells, nuclear atypia, microhemorrhage, and necrosis. They may arise in any region of the central nervous system, with a predilection for the cerebral hemispheres, basal ganglia, and commissural pathways. Clinical presentation most frequently occurs in the fifth or sixth decade of life with focal neurologic signs or seizures.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Goffin, E | 1 |
| Lamoral-Theys, D | 1 |
| Tajeddine, N | 1 |
| de Tullio, P | 1 |
| Mondin, L | 1 |
| Lefranc, F | 1 |
| Gailly, P | 1 |
| Rogister, B | 1 |
| Kiss, R | 1 |
| Pirotte, B | 1 |
1 other study available for pinacidil and Glioblastoma
| Article | Year |
|---|---|
N-Aryl-N'-(chroman-4-yl)ureas and thioureas display in vitro anticancer activity and selectivity on apoptosis-resistant glioblastoma cells: screening, synthesis of simplified derivatives, and structure-activity relationship analysis.
Topics: Antineoplastic Agents; Apoptosis; Astrocytes; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Drug | 2012 |