| Assay ID | Title | Year | Journal | Article |
|---|
| AID363280 | Inhibition of Escherichia coli thymidine phosphorylase | 2008 | European journal of medicinal chemistry, Jun, Volume: 43, Issue:6
| Xanthine oxidase-activated prodrugs of thymidine phosphorylase inhibitors. |
| AID1335972 | Inhibition of human placenta thymidine phosphorylase using [6-3H]dThd as substrate after 5 mins by scintillation counting method | 2016 | European journal of medicinal chemistry, Nov-29, Volume: 124 | Recent discovery of non-nucleobase thymidine phosphorylase inhibitors targeting cancer. |
| AID1402656 | Inhibition of thymidine phosphorylase (unknown origin) using thymidine as substrate after 1 hr by spectrophotometric analysis | 2018 | European journal of medicinal chemistry, Jan-20, Volume: 144 | Synthesis and biological evaluation of novel 1-(aryl-aldehyde-oxime)uracil derivatives as a new class of thymidine phosphorylase inhibitors. |
| AID1064689 | Inhibition of Escherichia coli thymidine phosphorylase using thymidine 5' mono phosphate as substrate after 10 mins by spectrophotometric analysis | 2014 | Bioorganic & medicinal chemistry, Feb-01, Volume: 22, Issue:3
| Synthesis and biological evaluation of novel oxadiazole derivatives: a new class of thymidine phosphorylase inhibitors as potential anti-tumor agents. |
| AID1587219 | Inhibition of human recombinant BACE-1 using 19F peptide as substrate measured after 5 hrs by fluorescence method | 2019 | European journal of medicinal chemistry, May-01, Volume: 169 | Advancement of multi-target drug discoveries and promising applications in the field of Alzheimer's disease. |
| AID757423 | Inhibition of recombinant Escherichia coli thymidine phosphorylase using thymidine as substrate by UV-spectrophotometric analysis | 2013 | European journal of medicinal chemistry, Jul, Volume: 65 | Synthesis of pyrazolo[1,5-a][1,3,5]triazine derivatives as inhibitors of thymidine phosphorylase. |
| AID1126865 | Cytotoxicity against human MDA-MB-231 cells assessed as cell viability at 25 to 100 uM after 72 hrs by MTT assay relative to control | 2014 | European journal of medicinal chemistry, May-06, Volume: 78 | Discovery of mixed type thymidine phosphorylase inhibitors endowed with antiangiogenic properties: synthesis, pharmacological evaluation and molecular docking study of 2-thioxo-pyrazolo[1,5-a][1,3,5]triazin-4-ones. Part II. |
| AID377599 | Inhibition of Escherichia coli thymidine phosphorylase by spectrophotometry | 2006 | Journal of natural products, Jun, Volume: 69, Issue:6
| Biotransformation of (-)-ambrox by cell suspension cultures of Actinidia deliciosa. |
| AID363293 | Inhibition of bovine xanthine oxidase using xanthine as a substrate | 2008 | European journal of medicinal chemistry, Jun, Volume: 43, Issue:6
| Xanthine oxidase-activated prodrugs of thymidine phosphorylase inhibitors. |
| AID757419 | Inhibition of Escherichia coli thymidine phosphorylase using thymidine as substrate by HPLC analysis | 2013 | European journal of medicinal chemistry, Jul, Volume: 65 | Synthesis of pyrazolo[1,5-a][1,3,5]triazine derivatives as inhibitors of thymidine phosphorylase. |
| AID1126864 | Inhibition of thymidine phosphorylase-mediated VEGF expression in human MDA-MB-231 cells at 100 uM by ELISA | 2014 | European journal of medicinal chemistry, May-06, Volume: 78 | Discovery of mixed type thymidine phosphorylase inhibitors endowed with antiangiogenic properties: synthesis, pharmacological evaluation and molecular docking study of 2-thioxo-pyrazolo[1,5-a][1,3,5]triazin-4-ones. Part II. |
| AID1055578 | Inhibition of Escherichia coli thymidine phosphorylase | 2013 | European journal of medicinal chemistry, , Volume: 70 | Fragment-based approach to the design of 5-chlorouracil-linked-pyrazolo[1,5-a][1,3,5]triazines as thymidine phosphorylase inhibitors. |
| AID1126863 | Inhibition of thymidine phosphorylase-mediated MMP-9 expression in human MDA-MB-231 cells at 100 uM by densitometric analysis | 2014 | European journal of medicinal chemistry, May-06, Volume: 78 | Discovery of mixed type thymidine phosphorylase inhibitors endowed with antiangiogenic properties: synthesis, pharmacological evaluation and molecular docking study of 2-thioxo-pyrazolo[1,5-a][1,3,5]triazin-4-ones. Part II. |
| AID211058 | Inhibitory activity against Escherichia coli thymidine phosphorylase | 2003 | Bioorganic & medicinal chemistry letters, Nov-03, Volume: 13, Issue:21
| Identification of a novel class of inhibitor of human and Escherichia coli thymidine phosphorylase by in silico screening. |
| AID213313 | Inhibition of Escherichia coli Thymidine Phosphorylase at a concentration of 100 uM after 60 minutes | 2000 | Journal of medicinal chemistry, Mar-09, Volume: 43, Issue:5
| Design, synthesis, and enzymatic evaluation of multisubstrate analogue inhibitors of Escherichia coli thymidine phosphorylase. |
| AID1587218 | Inhibition of human recombinant GSK-3beta using 19F peptide as substrate measured after 1.5 hrs by fluorescence method | 2019 | European journal of medicinal chemistry, May-01, Volume: 169 | Advancement of multi-target drug discoveries and promising applications in the field of Alzheimer's disease. |
| AID213307 | Inhibition of Escherichia coli TPase at a concentration of 25 uM after 60 minutes | 2000 | Journal of medicinal chemistry, Mar-09, Volume: 43, Issue:5
| Design, synthesis, and enzymatic evaluation of multisubstrate analogue inhibitors of Escherichia coli thymidine phosphorylase. |
| AID363289 | Inhibition of human recombinant thymidine phosphorylase | 2008 | European journal of medicinal chemistry, Jun, Volume: 43, Issue:6
| Xanthine oxidase-activated prodrugs of thymidine phosphorylase inhibitors. |
| AID241389 | Inhibitory concentration against thymidine phosphorylase of Escherichia coli | 2005 | Journal of medicinal chemistry, Jan-27, Volume: 48, Issue:2
| Aminoimidazolylmethyluracil analogues as potent inhibitors of thymidine phosphorylase and their bioreductive nitroimidazolyl prodrugs. |
| AID241246 | Inhibition of Thymidine phosphorylase from Escherichia coli | 2004 | Bioorganic & medicinal chemistry letters, Nov-01, Volume: 14, Issue:21
| Synthesis and enzymatic evaluation of xanthine oxidase-activated prodrugs based on inhibitors of thymidine phosphorylase. |
| AID1126857 | Inhibition of human recombinant thymidine phosphorylase expressed in Escherichia coli assessed as conversion of thymidine to thymine after 4 to 20 mins by spectrophotometric analysis | 2014 | European journal of medicinal chemistry, May-06, Volume: 78 | Discovery of mixed type thymidine phosphorylase inhibitors endowed with antiangiogenic properties: synthesis, pharmacological evaluation and molecular docking study of 2-thioxo-pyrazolo[1,5-a][1,3,5]triazin-4-ones. Part II. |
| AID415489 | Inhibition of Escherichia coli thymidine phosphorylase | 2009 | Bioorganic & medicinal chemistry, Apr-15, Volume: 17, Issue:8
| Schiff bases of 3-formylchromone as thymidine phosphorylase inhibitors. |
| AID1497669 | Inhibition of Escherichia coli thymidine phosphorylase pretreated for 10 mins followed by substrate addition measured at 10 mins interval for 30 mins by spectrophotometric method | 2018 | Bioorganic & medicinal chemistry, 07-23, Volume: 26, Issue:12
| Rational design of bis-indolylmethane-oxadiazole hybrids as inhibitors of thymidine phosphorylase. |
| AID1623806 | Inhibition of thymidine phosphorylase (unknown origin) | 2019 | Journal of medicinal chemistry, 02-14, Volume: 62, Issue:3
| Design of Novel Inhibitors of Human Thymidine Phosphorylase: Synthesis, Enzyme Inhibition, in Vitro Toxicity, and Impact on Human Glioblastoma Cancer. |
| AID765733 | Inhibition of human recombinant thymidine phosphorylase expressed in Escherichia coli using thymidine as substrate after 4 to 20 mins by spectrophotometry | 2013 | European journal of medicinal chemistry, Sep, Volume: 67 | A structure-activity relationship study of 1,2,4-triazolo[1,5-a][1,3,5]triazin-5,7-dione and its 5-thioxo analogues on anti-thymidine phosphorylase and associated anti-angiogenic activities. |
| AID363292 | Inhibition of bovine xanthine oxidase using hypoxanthine as a substrate | 2008 | European journal of medicinal chemistry, Jun, Volume: 43, Issue:6
| Xanthine oxidase-activated prodrugs of thymidine phosphorylase inhibitors. |
| AID1802574 | Thymidine Phosphorylase Inhibition Assay from Article 10.1016/j.bioorg.2016.11.007: \\Thymidine esters as substrate analogue inhibitors of angiogenic enzyme thymidine phosphorylase in vitro.\\ | 2017 | Bioorganic chemistry, 02, Volume: 70 | Thymidine esters as substrate analogue inhibitors of angiogenic enzyme thymidine phosphorylase in vitro. |
| AID1802575 | Kinetic Assay from Article 10.1016/j.bioorg.2016.11.007: \\Thymidine esters as substrate analogue inhibitors of angiogenic enzyme thymidine phosphorylase in vitro.\\ | 2017 | Bioorganic chemistry, 02, Volume: 70 | Thymidine esters as substrate analogue inhibitors of angiogenic enzyme thymidine phosphorylase in vitro. |
| AID1801488 | Thymidine Phosphorylase Inhibition Assay from Article 10.1016/j.bioorg.2015.10.006: \\2-Arylquinazolin-4(3H)-ones: A novel class of thymidine phosphorylase inhibitors.\\ | 2015 | Bioorganic chemistry, Dec, Volume: 63 | 2-Arylquinazolin-4(3H)-ones: A novel class of thymidine phosphorylase inhibitors. |
| AID1801943 | Thymidine Phosphorylase Assay from Article 10.1016/j.bioorg.2016.07.010: \\In silico binding analysis and SAR elucidations of newly designed benzopyrazine analogs as potent inhibitors of thymidine phosphorylase.\\ | 2016 | Bioorganic chemistry, 10, Volume: 68 | In silico binding analysis and SAR elucidations of newly designed benzopyrazine analogs as potent inhibitors of thymidine phosphorylase. |
| AID1801047 | Thymidine Phosphorylase Inhibition Assay from Article 10.1016/j.bioorg.2015.04.003: \\Synthesis, thymidine phosphorylase inhibition and molecular modeling studies of 1,3,4-oxadiazole-2-thione derivatives.\\ | 2015 | Bioorganic chemistry, Jun, Volume: 60 | Synthesis, thymidine phosphorylase inhibition and molecular modeling studies of 1,3,4-oxadiazole-2-thione derivatives. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |